Endocrine parameters in participants who received follitropin delta (safety analysis set).
| Mean . | GnRH agonist protocol . | GnRH antagonist protocol . |
|---|---|---|
| n = 202 . | n = 204 . | |
| Oestradiol, pmol/l | ||
| Stimulation Day 1 | 34.9 (34.9–89.6) | 155.6 (121.3–198.9 |
| Stimulation Day 6 | 899.5 (438.1–1482.7) | 2408.7 (1426.8–3678.1) |
| End of stimulation | 6846.6 (4794.7–9584.7) | 5645.9 (3782.9–8023.6) |
| Oocyte retrieval | 3174.1 (2041.6–4471.2) | 2861.9 (1766.3–4091.2) |
| Progesterone, nmol/l | ||
| Stimulation Day 1 | 0.8 (0.8–2.0) | 1.9 (0.8–2.9) |
| Stimulation Day 6 | 1.8 (0.8–2.4) | 2.4 (1.7–3.4) |
| End of stimulation | 2.8 (2.1–3.9) | 2.9 (2.3–4.3) |
| Oocyte retrieval | 23.9 (16.3–32.6) | 23.8 (17.1–32.3) |
| Mean . | GnRH agonist protocol . | GnRH antagonist protocol . |
|---|---|---|
| n = 202 . | n = 204 . | |
| Oestradiol, pmol/l | ||
| Stimulation Day 1 | 34.9 (34.9–89.6) | 155.6 (121.3–198.9 |
| Stimulation Day 6 | 899.5 (438.1–1482.7) | 2408.7 (1426.8–3678.1) |
| End of stimulation | 6846.6 (4794.7–9584.7) | 5645.9 (3782.9–8023.6) |
| Oocyte retrieval | 3174.1 (2041.6–4471.2) | 2861.9 (1766.3–4091.2) |
| Progesterone, nmol/l | ||
| Stimulation Day 1 | 0.8 (0.8–2.0) | 1.9 (0.8–2.9) |
| Stimulation Day 6 | 1.8 (0.8–2.4) | 2.4 (1.7–3.4) |
| End of stimulation | 2.8 (2.1–3.9) | 2.9 (2.3–4.3) |
| Oocyte retrieval | 23.9 (16.3–32.6) | 23.8 (17.1–32.3) |
Data are median (interquartile range).
Progesterone values below LLOQ (<1.59 nmol/l) are set to LLOQ/2, i.e. 0.79 nmol/l rounded off to 0.8 nmol/l. Oestradiol values below LLOQ (<69.8 pmol/l) are set to LLOQ/2, i.e. 34.9 pmol/l.
LLOQ, lower limit of quantification.
Endocrine parameters in participants who received follitropin delta (safety analysis set).
| Mean . | GnRH agonist protocol . | GnRH antagonist protocol . |
|---|---|---|
| n = 202 . | n = 204 . | |
| Oestradiol, pmol/l | ||
| Stimulation Day 1 | 34.9 (34.9–89.6) | 155.6 (121.3–198.9 |
| Stimulation Day 6 | 899.5 (438.1–1482.7) | 2408.7 (1426.8–3678.1) |
| End of stimulation | 6846.6 (4794.7–9584.7) | 5645.9 (3782.9–8023.6) |
| Oocyte retrieval | 3174.1 (2041.6–4471.2) | 2861.9 (1766.3–4091.2) |
| Progesterone, nmol/l | ||
| Stimulation Day 1 | 0.8 (0.8–2.0) | 1.9 (0.8–2.9) |
| Stimulation Day 6 | 1.8 (0.8–2.4) | 2.4 (1.7–3.4) |
| End of stimulation | 2.8 (2.1–3.9) | 2.9 (2.3–4.3) |
| Oocyte retrieval | 23.9 (16.3–32.6) | 23.8 (17.1–32.3) |
| Mean . | GnRH agonist protocol . | GnRH antagonist protocol . |
|---|---|---|
| n = 202 . | n = 204 . | |
| Oestradiol, pmol/l | ||
| Stimulation Day 1 | 34.9 (34.9–89.6) | 155.6 (121.3–198.9 |
| Stimulation Day 6 | 899.5 (438.1–1482.7) | 2408.7 (1426.8–3678.1) |
| End of stimulation | 6846.6 (4794.7–9584.7) | 5645.9 (3782.9–8023.6) |
| Oocyte retrieval | 3174.1 (2041.6–4471.2) | 2861.9 (1766.3–4091.2) |
| Progesterone, nmol/l | ||
| Stimulation Day 1 | 0.8 (0.8–2.0) | 1.9 (0.8–2.9) |
| Stimulation Day 6 | 1.8 (0.8–2.4) | 2.4 (1.7–3.4) |
| End of stimulation | 2.8 (2.1–3.9) | 2.9 (2.3–4.3) |
| Oocyte retrieval | 23.9 (16.3–32.6) | 23.8 (17.1–32.3) |
Data are median (interquartile range).
Progesterone values below LLOQ (<1.59 nmol/l) are set to LLOQ/2, i.e. 0.79 nmol/l rounded off to 0.8 nmol/l. Oestradiol values below LLOQ (<69.8 pmol/l) are set to LLOQ/2, i.e. 34.9 pmol/l.
LLOQ, lower limit of quantification.
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