Table 1.

Grading of Recommendations Assessment, Development and Evaluation Evidence Profile: N95/Surgical Mask Compared With No Personal Protective Equipment (No Mask) or Infrequent PPE (Inconsistent Use of Mask)

Certainty AssessmentNo. of PatientsEffectCertainty
No. of StudiesStudy DesignRisk of BiasInconsistencyIndirectnessImprecisionOther ConsiderationsN95No Personal Protective EquipmentRelative (95% CI)Absolute (95% CI)
Severe acute respiratory syndrome infection
5 [20–24]ObservationalNot seriousNot seriousNot serious aNot seriousStrong association b9/163 (5.5%)86/234 (36.8%)Odds ratio 0.12 (.06 –.26)302 fewer per 1000 (from 334 fewer to 236 fewer)⨁⨁⨁◯ Moderate
Certainty AssessmentNo. of PatientsEffectCertainty
No. of StudiesStudy DesignRisk of BiasInconsistencyIndirectnessImprecisionOther ConsiderationsN95No Personal Protective EquipmentRelative (95% CI)Absolute (95% CI)
Severe acute respiratory syndrome infection
5 [20–24]ObservationalNot seriousNot seriousNot serious aNot seriousStrong association b9/163 (5.5%)86/234 (36.8%)Odds ratio 0.12 (.06 –.26)302 fewer per 1000 (from 334 fewer to 236 fewer)⨁⨁⨁◯ Moderate

Abbreviation: CI, confidence interval.

aAlthough the studies reported on the severe acute respiratory syndrome outbreak, given the similarities between severe acute respiratory syndrome coronavirus 1 and severe acute respiratory syndrome coronavirus 2, we did not rate down for indirectness.

bThe evidence was rated up for large magnitude of effect.

Table 1.

Grading of Recommendations Assessment, Development and Evaluation Evidence Profile: N95/Surgical Mask Compared With No Personal Protective Equipment (No Mask) or Infrequent PPE (Inconsistent Use of Mask)

Certainty AssessmentNo. of PatientsEffectCertainty
No. of StudiesStudy DesignRisk of BiasInconsistencyIndirectnessImprecisionOther ConsiderationsN95No Personal Protective EquipmentRelative (95% CI)Absolute (95% CI)
Severe acute respiratory syndrome infection
5 [20–24]ObservationalNot seriousNot seriousNot serious aNot seriousStrong association b9/163 (5.5%)86/234 (36.8%)Odds ratio 0.12 (.06 –.26)302 fewer per 1000 (from 334 fewer to 236 fewer)⨁⨁⨁◯ Moderate
Certainty AssessmentNo. of PatientsEffectCertainty
No. of StudiesStudy DesignRisk of BiasInconsistencyIndirectnessImprecisionOther ConsiderationsN95No Personal Protective EquipmentRelative (95% CI)Absolute (95% CI)
Severe acute respiratory syndrome infection
5 [20–24]ObservationalNot seriousNot seriousNot serious aNot seriousStrong association b9/163 (5.5%)86/234 (36.8%)Odds ratio 0.12 (.06 –.26)302 fewer per 1000 (from 334 fewer to 236 fewer)⨁⨁⨁◯ Moderate

Abbreviation: CI, confidence interval.

aAlthough the studies reported on the severe acute respiratory syndrome outbreak, given the similarities between severe acute respiratory syndrome coronavirus 1 and severe acute respiratory syndrome coronavirus 2, we did not rate down for indirectness.

bThe evidence was rated up for large magnitude of effect.

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