Table 2:

Variables associated with TmP/GFR in a multivariable model.

Baseline valuesβ (95% CI)P-value
Age, years0.002 (0.00; 0.004).1
Male sex–0.2 (–0.2; –0.1)<.001
BMI, kg/m2–0.002 (–0.007; 0.002).3
PKD1 genotype0.01 (–0.03; 0.06).6
eGFR, mL/min/1.73 m20.002 (0.001; 0.004)<.001
htTKV, mL/m0.05 (–0.04; 0.13).3
Tolvaptan treatment0.02 (–0.05; 0.08).6
Diuretic treatment–0.04 (–0.09; 0.01).2
25-OH vitamin D, nmol/mL–0.01 (–0.1–0.08).8
PTH, pmol/mL–0.2 (–0.3; –0.06).002
Serum calcium, mmol/dL0.4 (–0.8; 1.5).6
Plasma copeptin, pmol/L–0.08 (–0.1; –0.08).03
FGF-23, RU/mL0.1 (0.03; 0.2).01
Proteinuria (g/24 h)0.01 (–0.08; 0.08)1.0
Urea excretion (mmol/24 h)–0.00 (–0.00; 0.000).3
Baseline valuesβ (95% CI)P-value
Age, years0.002 (0.00; 0.004).1
Male sex–0.2 (–0.2; –0.1)<.001
BMI, kg/m2–0.002 (–0.007; 0.002).3
PKD1 genotype0.01 (–0.03; 0.06).6
eGFR, mL/min/1.73 m20.002 (0.001; 0.004)<.001
htTKV, mL/m0.05 (–0.04; 0.13).3
Tolvaptan treatment0.02 (–0.05; 0.08).6
Diuretic treatment–0.04 (–0.09; 0.01).2
25-OH vitamin D, nmol/mL–0.01 (–0.1–0.08).8
PTH, pmol/mL–0.2 (–0.3; –0.06).002
Serum calcium, mmol/dL0.4 (–0.8; 1.5).6
Plasma copeptin, pmol/L–0.08 (–0.1; –0.08).03
FGF-23, RU/mL0.1 (0.03; 0.2).01
Proteinuria (g/24 h)0.01 (–0.08; 0.08)1.0
Urea excretion (mmol/24 h)–0.00 (–0.00; 0.000).3

Log transformation performed in non-normally distributed variables: htTKV, 25-OH vitamin D, PTH, serum calcium, plasma copeptin, FGF-23 and proteinuria.

Bold values means significant difference with p < 0.05.

Table 2:

Variables associated with TmP/GFR in a multivariable model.

Baseline valuesβ (95% CI)P-value
Age, years0.002 (0.00; 0.004).1
Male sex–0.2 (–0.2; –0.1)<.001
BMI, kg/m2–0.002 (–0.007; 0.002).3
PKD1 genotype0.01 (–0.03; 0.06).6
eGFR, mL/min/1.73 m20.002 (0.001; 0.004)<.001
htTKV, mL/m0.05 (–0.04; 0.13).3
Tolvaptan treatment0.02 (–0.05; 0.08).6
Diuretic treatment–0.04 (–0.09; 0.01).2
25-OH vitamin D, nmol/mL–0.01 (–0.1–0.08).8
PTH, pmol/mL–0.2 (–0.3; –0.06).002
Serum calcium, mmol/dL0.4 (–0.8; 1.5).6
Plasma copeptin, pmol/L–0.08 (–0.1; –0.08).03
FGF-23, RU/mL0.1 (0.03; 0.2).01
Proteinuria (g/24 h)0.01 (–0.08; 0.08)1.0
Urea excretion (mmol/24 h)–0.00 (–0.00; 0.000).3
Baseline valuesβ (95% CI)P-value
Age, years0.002 (0.00; 0.004).1
Male sex–0.2 (–0.2; –0.1)<.001
BMI, kg/m2–0.002 (–0.007; 0.002).3
PKD1 genotype0.01 (–0.03; 0.06).6
eGFR, mL/min/1.73 m20.002 (0.001; 0.004)<.001
htTKV, mL/m0.05 (–0.04; 0.13).3
Tolvaptan treatment0.02 (–0.05; 0.08).6
Diuretic treatment–0.04 (–0.09; 0.01).2
25-OH vitamin D, nmol/mL–0.01 (–0.1–0.08).8
PTH, pmol/mL–0.2 (–0.3; –0.06).002
Serum calcium, mmol/dL0.4 (–0.8; 1.5).6
Plasma copeptin, pmol/L–0.08 (–0.1; –0.08).03
FGF-23, RU/mL0.1 (0.03; 0.2).01
Proteinuria (g/24 h)0.01 (–0.08; 0.08)1.0
Urea excretion (mmol/24 h)–0.00 (–0.00; 0.000).3

Log transformation performed in non-normally distributed variables: htTKV, 25-OH vitamin D, PTH, serum calcium, plasma copeptin, FGF-23 and proteinuria.

Bold values means significant difference with p < 0.05.

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