Table 1.

Human oocyte maturation-related proteome.

Young group
AMA group
Low in MII vs GVHigh in MII vs GVLow in MII vs GVHigh in MII vs GV
TranslationYBOX2, RS14, RL10A, RS16, RS9, RS17, RS8, RS20, KS6A3NDYBOX2, RSSA, ZAR1, CAPR2, RL23A, PATL2, RL8, RL24, RS18ND
Microtubule cytoskeletonFLNA, DCTN1, GCP3, TBB5TACC3, ACTL8, PCNA, MP2K1, NUDC2, TBCANDACTL8, PCNA, MP2K1, TBB8B, TBA4B
Cell cycle (meiosis)H18SPDLY, AURKA, WEE2, BUB1BH18SPDLY, AURKA, BUB1B, WEE2, REEP4
Young group
AMA group
Low in MII vs GVHigh in MII vs GVLow in MII vs GVHigh in MII vs GV
TranslationYBOX2, RS14, RL10A, RS16, RS9, RS17, RS8, RS20, KS6A3NDYBOX2, RSSA, ZAR1, CAPR2, RL23A, PATL2, RL8, RL24, RS18ND
Microtubule cytoskeletonFLNA, DCTN1, GCP3, TBB5TACC3, ACTL8, PCNA, MP2K1, NUDC2, TBCANDACTL8, PCNA, MP2K1, TBB8B, TBA4B
Cell cycle (meiosis)H18SPDLY, AURKA, WEE2, BUB1BH18SPDLY, AURKA, BUB1B, WEE2, REEP4

ND, non-detected; AMA, advanced maternal age; GV, germinal vesicle; MII, metaphase II; Young: 18–30 years; AMA: 37–43 years.

Table 1.

Human oocyte maturation-related proteome.

Young group
AMA group
Low in MII vs GVHigh in MII vs GVLow in MII vs GVHigh in MII vs GV
TranslationYBOX2, RS14, RL10A, RS16, RS9, RS17, RS8, RS20, KS6A3NDYBOX2, RSSA, ZAR1, CAPR2, RL23A, PATL2, RL8, RL24, RS18ND
Microtubule cytoskeletonFLNA, DCTN1, GCP3, TBB5TACC3, ACTL8, PCNA, MP2K1, NUDC2, TBCANDACTL8, PCNA, MP2K1, TBB8B, TBA4B
Cell cycle (meiosis)H18SPDLY, AURKA, WEE2, BUB1BH18SPDLY, AURKA, BUB1B, WEE2, REEP4
Young group
AMA group
Low in MII vs GVHigh in MII vs GVLow in MII vs GVHigh in MII vs GV
TranslationYBOX2, RS14, RL10A, RS16, RS9, RS17, RS8, RS20, KS6A3NDYBOX2, RSSA, ZAR1, CAPR2, RL23A, PATL2, RL8, RL24, RS18ND
Microtubule cytoskeletonFLNA, DCTN1, GCP3, TBB5TACC3, ACTL8, PCNA, MP2K1, NUDC2, TBCANDACTL8, PCNA, MP2K1, TBB8B, TBA4B
Cell cycle (meiosis)H18SPDLY, AURKA, WEE2, BUB1BH18SPDLY, AURKA, BUB1B, WEE2, REEP4

ND, non-detected; AMA, advanced maternal age; GV, germinal vesicle; MII, metaphase II; Young: 18–30 years; AMA: 37–43 years.

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