Table 4

Cox multivariable models—deaths or HF

aHR (95% CI)P-value
Model clinical + echo conventional χ² = 34.7; P < 0.001
Age1.05 (1.01–1.08)0.006
NYHA Class ≥31.72 (1.08–2.75)0.02
Mean gradient1.00 (0.98–1.01)0.694
LVEF0.98 (0.96–0.99)0.010
RV dysfunction0.88 (0.47–1.64)0.696
Model clinical + echo conventional + LV GLS χ² = 41.0; P < 0.001
Age1.04 (1.01–1.08)0.008
NYHA Class ≥31.55 (0.93–2.40)0.095
Mean gradient0.99 (0.98–1.01)0.538
LVEF1.00 (0.99–1.01)0.820
RV dysfunction0.78 (0.42–1.45)0.424
LV GLS0.90 (0.85–0.97)0.007
Model clinical + echo conventional + LV GLS + PALS χ² = 44.9; P < 0.001
Age1.04 (1.01–1.07)0.03
NYHA Class ≥31.42 (0.89–2.23)0.095
Mean gradient0.99 (0.98–1.01)0.538
LVEF0.99 (0.97–1.01)0.820
RV dysfunction0.72 (0.39–1.34)0.291
LV GLS0.95 (0.88–1.03)0.299
PALS0.96 (0.93–0.99)0.031
aHR (95% CI)P-value
Model clinical + echo conventional χ² = 34.7; P < 0.001
Age1.05 (1.01–1.08)0.006
NYHA Class ≥31.72 (1.08–2.75)0.02
Mean gradient1.00 (0.98–1.01)0.694
LVEF0.98 (0.96–0.99)0.010
RV dysfunction0.88 (0.47–1.64)0.696
Model clinical + echo conventional + LV GLS χ² = 41.0; P < 0.001
Age1.04 (1.01–1.08)0.008
NYHA Class ≥31.55 (0.93–2.40)0.095
Mean gradient0.99 (0.98–1.01)0.538
LVEF1.00 (0.99–1.01)0.820
RV dysfunction0.78 (0.42–1.45)0.424
LV GLS0.90 (0.85–0.97)0.007
Model clinical + echo conventional + LV GLS + PALS χ² = 44.9; P < 0.001
Age1.04 (1.01–1.07)0.03
NYHA Class ≥31.42 (0.89–2.23)0.095
Mean gradient0.99 (0.98–1.01)0.538
LVEF0.99 (0.97–1.01)0.820
RV dysfunction0.72 (0.39–1.34)0.291
LV GLS0.95 (0.88–1.03)0.299
PALS0.96 (0.93–0.99)0.031

Bold values represent p <0.05 (statistical significant).

aHR, adjusted hazard ratio; LV GLS, left ventricle global longitudinal strain; LVEF, left ventricle ejection fraction; NYHA, New York heart association; PALS, peak atrial longitudinal strain; RV, right ventricle.

Table 4

Cox multivariable models—deaths or HF

aHR (95% CI)P-value
Model clinical + echo conventional χ² = 34.7; P < 0.001
Age1.05 (1.01–1.08)0.006
NYHA Class ≥31.72 (1.08–2.75)0.02
Mean gradient1.00 (0.98–1.01)0.694
LVEF0.98 (0.96–0.99)0.010
RV dysfunction0.88 (0.47–1.64)0.696
Model clinical + echo conventional + LV GLS χ² = 41.0; P < 0.001
Age1.04 (1.01–1.08)0.008
NYHA Class ≥31.55 (0.93–2.40)0.095
Mean gradient0.99 (0.98–1.01)0.538
LVEF1.00 (0.99–1.01)0.820
RV dysfunction0.78 (0.42–1.45)0.424
LV GLS0.90 (0.85–0.97)0.007
Model clinical + echo conventional + LV GLS + PALS χ² = 44.9; P < 0.001
Age1.04 (1.01–1.07)0.03
NYHA Class ≥31.42 (0.89–2.23)0.095
Mean gradient0.99 (0.98–1.01)0.538
LVEF0.99 (0.97–1.01)0.820
RV dysfunction0.72 (0.39–1.34)0.291
LV GLS0.95 (0.88–1.03)0.299
PALS0.96 (0.93–0.99)0.031
aHR (95% CI)P-value
Model clinical + echo conventional χ² = 34.7; P < 0.001
Age1.05 (1.01–1.08)0.006
NYHA Class ≥31.72 (1.08–2.75)0.02
Mean gradient1.00 (0.98–1.01)0.694
LVEF0.98 (0.96–0.99)0.010
RV dysfunction0.88 (0.47–1.64)0.696
Model clinical + echo conventional + LV GLS χ² = 41.0; P < 0.001
Age1.04 (1.01–1.08)0.008
NYHA Class ≥31.55 (0.93–2.40)0.095
Mean gradient0.99 (0.98–1.01)0.538
LVEF1.00 (0.99–1.01)0.820
RV dysfunction0.78 (0.42–1.45)0.424
LV GLS0.90 (0.85–0.97)0.007
Model clinical + echo conventional + LV GLS + PALS χ² = 44.9; P < 0.001
Age1.04 (1.01–1.07)0.03
NYHA Class ≥31.42 (0.89–2.23)0.095
Mean gradient0.99 (0.98–1.01)0.538
LVEF0.99 (0.97–1.01)0.820
RV dysfunction0.72 (0.39–1.34)0.291
LV GLS0.95 (0.88–1.03)0.299
PALS0.96 (0.93–0.99)0.031

Bold values represent p <0.05 (statistical significant).

aHR, adjusted hazard ratio; LV GLS, left ventricle global longitudinal strain; LVEF, left ventricle ejection fraction; NYHA, New York heart association; PALS, peak atrial longitudinal strain; RV, right ventricle.

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