Table 3
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Cox multivariable models—deaths or HF in patients under medical management

aHR (95% CI)P-value
Model clinical + conventional echo χ² = 47.1; P < 0.001
Age1.04 (1.01–1.08)0.024
NYHA Class ≥31.55 (1.12–3.69)0.019
Mean gradient1.03 (1.01–1.04)0.002
LVEF0.97 (0.96–0.99)0.027
RV dysfunction1.43 (0.71–2.8)0.316
Model clinical + conventional echo + LV GLS χ² = 51.6; P < 0.001
Age1.04 (1.01–1.08)0.02
NYHA Class ≥31.72 (0.96–3.1)0.068
Mean gradient1.02 (1.01–1.04)0.016
LVEF0.98 (0.97–1.02)0.955
RV dysfunction0.61 (0.39–2.5)0.556
LV GLS0.95 (0.88–1.03)0.015
Model clinical + conventional echo + LV GLS + PALS χ² = 56.4; P < 0.001
Age1.04 (1.01–1.08)0.104
NYHA Class ≥31.72 (0.94–2.9)0.098
Mean gradient1.02 (1.01–1.04)0.008
LVEF0.99 (0.97–1.02)0.671
RV dysfunction1.16 (0.57–2.4)0.629
LV GLS0.95 (0.86–1.05)0.311
PALS0.95 (0.91–0.99)0.017
aHR (95% CI)P-value
Model clinical + conventional echo χ² = 47.1; P < 0.001
Age1.04 (1.01–1.08)0.024
NYHA Class ≥31.55 (1.12–3.69)0.019
Mean gradient1.03 (1.01–1.04)0.002
LVEF0.97 (0.96–0.99)0.027
RV dysfunction1.43 (0.71–2.8)0.316
Model clinical + conventional echo + LV GLS χ² = 51.6; P < 0.001
Age1.04 (1.01–1.08)0.02
NYHA Class ≥31.72 (0.96–3.1)0.068
Mean gradient1.02 (1.01–1.04)0.016
LVEF0.98 (0.97–1.02)0.955
RV dysfunction0.61 (0.39–2.5)0.556
LV GLS0.95 (0.88–1.03)0.015
Model clinical + conventional echo + LV GLS + PALS χ² = 56.4; P < 0.001
Age1.04 (1.01–1.08)0.104
NYHA Class ≥31.72 (0.94–2.9)0.098
Mean gradient1.02 (1.01–1.04)0.008
LVEF0.99 (0.97–1.02)0.671
RV dysfunction1.16 (0.57–2.4)0.629
LV GLS0.95 (0.86–1.05)0.311
PALS0.95 (0.91–0.99)0.017

Bold values represent p < 0.05 (statistical significant).

aHR, adjusted hazard ratio; LV GLS, left ventricle global longitudinal strain; LVEF, left ventricle ejection fraction; NYHA, New York heart association; PALS, peak atrial longitudinal strain; RV, right ventricle.

Table 3
Open in new tab

Cox multivariable models—deaths or HF in patients under medical management

aHR (95% CI)P-value
Model clinical + conventional echo χ² = 47.1; P < 0.001
Age1.04 (1.01–1.08)0.024
NYHA Class ≥31.55 (1.12–3.69)0.019
Mean gradient1.03 (1.01–1.04)0.002
LVEF0.97 (0.96–0.99)0.027
RV dysfunction1.43 (0.71–2.8)0.316
Model clinical + conventional echo + LV GLS χ² = 51.6; P < 0.001
Age1.04 (1.01–1.08)0.02
NYHA Class ≥31.72 (0.96–3.1)0.068
Mean gradient1.02 (1.01–1.04)0.016
LVEF0.98 (0.97–1.02)0.955
RV dysfunction0.61 (0.39–2.5)0.556
LV GLS0.95 (0.88–1.03)0.015
Model clinical + conventional echo + LV GLS + PALS χ² = 56.4; P < 0.001
Age1.04 (1.01–1.08)0.104
NYHA Class ≥31.72 (0.94–2.9)0.098
Mean gradient1.02 (1.01–1.04)0.008
LVEF0.99 (0.97–1.02)0.671
RV dysfunction1.16 (0.57–2.4)0.629
LV GLS0.95 (0.86–1.05)0.311
PALS0.95 (0.91–0.99)0.017
aHR (95% CI)P-value
Model clinical + conventional echo χ² = 47.1; P < 0.001
Age1.04 (1.01–1.08)0.024
NYHA Class ≥31.55 (1.12–3.69)0.019
Mean gradient1.03 (1.01–1.04)0.002
LVEF0.97 (0.96–0.99)0.027
RV dysfunction1.43 (0.71–2.8)0.316
Model clinical + conventional echo + LV GLS χ² = 51.6; P < 0.001
Age1.04 (1.01–1.08)0.02
NYHA Class ≥31.72 (0.96–3.1)0.068
Mean gradient1.02 (1.01–1.04)0.016
LVEF0.98 (0.97–1.02)0.955
RV dysfunction0.61 (0.39–2.5)0.556
LV GLS0.95 (0.88–1.03)0.015
Model clinical + conventional echo + LV GLS + PALS χ² = 56.4; P < 0.001
Age1.04 (1.01–1.08)0.104
NYHA Class ≥31.72 (0.94–2.9)0.098
Mean gradient1.02 (1.01–1.04)0.008
LVEF0.99 (0.97–1.02)0.671
RV dysfunction1.16 (0.57–2.4)0.629
LV GLS0.95 (0.86–1.05)0.311
PALS0.95 (0.91–0.99)0.017

Bold values represent p < 0.05 (statistical significant).

aHR, adjusted hazard ratio; LV GLS, left ventricle global longitudinal strain; LVEF, left ventricle ejection fraction; NYHA, New York heart association; PALS, peak atrial longitudinal strain; RV, right ventricle.

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