Relative Risk and Number Needed to Harm With Invasive Fungal Infections in Patients With Chronic Lmphocytic Leukemia on a Bruton Tyrosine Kinase Inhibitor at 5 Years
| Invasive Fungal Infection . | Episodesa, No. (%) . | Relative Risk (95% CI) . | NNH . |
|---|---|---|---|
| Pneumocystis jirovecii pneumonia | 29 (0.5%) | 2.1 (1.1 - 4.0) | 358 |
| Cryptococcosis | 16 (0.3%) | 1.6 (0.7 - 3.5) | 894 |
| Aspergillosis | 10 (0.2%) | 0.5 (0.2 - 1.1) | 536b |
| Invasive candidiasis | 189 (3.5%) | 1.3 (1.1 - 1.6) | 120 |
| Invasive Fungal Infection . | Episodesa, No. (%) . | Relative Risk (95% CI) . | NNH . |
|---|---|---|---|
| Pneumocystis jirovecii pneumonia | 29 (0.5%) | 2.1 (1.1 - 4.0) | 358 |
| Cryptococcosis | 16 (0.3%) | 1.6 (0.7 - 3.5) | 894 |
| Aspergillosis | 10 (0.2%) | 0.5 (0.2 - 1.1) | 536b |
| Invasive candidiasis | 189 (3.5%) | 1.3 (1.1 - 1.6) | 120 |
Abbreviation: NNH, number needed to harm.
aAmong 5358 matched patients with chronic lymphocytic leukemia on a Bruton tyrosine kinase inhibitor.
bNumber needed to treat.
Relative Risk and Number Needed to Harm With Invasive Fungal Infections in Patients With Chronic Lmphocytic Leukemia on a Bruton Tyrosine Kinase Inhibitor at 5 Years
| Invasive Fungal Infection . | Episodesa, No. (%) . | Relative Risk (95% CI) . | NNH . |
|---|---|---|---|
| Pneumocystis jirovecii pneumonia | 29 (0.5%) | 2.1 (1.1 - 4.0) | 358 |
| Cryptococcosis | 16 (0.3%) | 1.6 (0.7 - 3.5) | 894 |
| Aspergillosis | 10 (0.2%) | 0.5 (0.2 - 1.1) | 536b |
| Invasive candidiasis | 189 (3.5%) | 1.3 (1.1 - 1.6) | 120 |
| Invasive Fungal Infection . | Episodesa, No. (%) . | Relative Risk (95% CI) . | NNH . |
|---|---|---|---|
| Pneumocystis jirovecii pneumonia | 29 (0.5%) | 2.1 (1.1 - 4.0) | 358 |
| Cryptococcosis | 16 (0.3%) | 1.6 (0.7 - 3.5) | 894 |
| Aspergillosis | 10 (0.2%) | 0.5 (0.2 - 1.1) | 536b |
| Invasive candidiasis | 189 (3.5%) | 1.3 (1.1 - 1.6) | 120 |
Abbreviation: NNH, number needed to harm.
aAmong 5358 matched patients with chronic lymphocytic leukemia on a Bruton tyrosine kinase inhibitor.
bNumber needed to treat.
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