| Total number of patients | 1162 |
| Males, n (%) | 791 (68.1) |
| Females, n (%) | 371 (31.9) |
| Age (years), mean ± SD | 70.2 ± 13.5 |
| Body surface area (m2), mean ± SD | 1.99 ± 0.28 |
| Bicuspid, n (%) | 257 (22.1) |
| Marfan—connective tissue disorders, n (%) | 36 (3.1) |
| Family history | |
| Proven | 248 (21.3) |
| Likely | 75 (6.5) |
| Possible | 51 (4.4) |
| Unknown | 136 (11.7) |
| None | 652 (56.1) |
| Previous cardiac surgeries, n (%) | |
| CABG | 37 (3.2) |
| AVR | 64 (5.5) |
| MVR | 13 (1.1) |
| CABG + AVR | 17 (1.4) |
| AVR + MVR | 2 (0.02) |
| CABG + AVR + MVR | 2 (0.02) |
| Hypertension, n (%) | 716 (61.6) |
| Diabetes mellitus, n (%) | 178 (15.3) |
| Endpoints, n (%) | |
| Acute type A dissection | 120 (10.3) |
| Rupture | 2 (0.2) |
| Ascending aorta death | 8 (0.7) |
| Composite endpoint 1 | 130 (11.2) |
| Unknown or other cause of death | 119 (10.2) |
| Composite endpoint 2 | 249 (21.4) |
| Surgery, pre-emptive | 545 (46.9) |
| Total number of patients | 1162 |
| Males, n (%) | 791 (68.1) |
| Females, n (%) | 371 (31.9) |
| Age (years), mean ± SD | 70.2 ± 13.5 |
| Body surface area (m2), mean ± SD | 1.99 ± 0.28 |
| Bicuspid, n (%) | 257 (22.1) |
| Marfan—connective tissue disorders, n (%) | 36 (3.1) |
| Family history | |
| Proven | 248 (21.3) |
| Likely | 75 (6.5) |
| Possible | 51 (4.4) |
| Unknown | 136 (11.7) |
| None | 652 (56.1) |
| Previous cardiac surgeries, n (%) | |
| CABG | 37 (3.2) |
| AVR | 64 (5.5) |
| MVR | 13 (1.1) |
| CABG + AVR | 17 (1.4) |
| AVR + MVR | 2 (0.02) |
| CABG + AVR + MVR | 2 (0.02) |
| Hypertension, n (%) | 716 (61.6) |
| Diabetes mellitus, n (%) | 178 (15.3) |
| Endpoints, n (%) | |
| Acute type A dissection | 120 (10.3) |
| Rupture | 2 (0.2) |
| Ascending aorta death | 8 (0.7) |
| Composite endpoint 1 | 130 (11.2) |
| Unknown or other cause of death | 119 (10.2) |
| Composite endpoint 2 | 249 (21.4) |
| Surgery, pre-emptive | 545 (46.9) |
Composite endpoint 1 consists of acute type A dissection, rupture and ascending aorta-related death; and Composite endpoint 2 of acute type A dissection, rupture and all cause death data are provided as mean ± SD or number (percentage).
AVR: aortic valve replacement; CABG: coronary artery bypass grafting; MVR: mitral valve replacement; SD: standard deviation.
| Total number of patients | 1162 |
| Males, n (%) | 791 (68.1) |
| Females, n (%) | 371 (31.9) |
| Age (years), mean ± SD | 70.2 ± 13.5 |
| Body surface area (m2), mean ± SD | 1.99 ± 0.28 |
| Bicuspid, n (%) | 257 (22.1) |
| Marfan—connective tissue disorders, n (%) | 36 (3.1) |
| Family history | |
| Proven | 248 (21.3) |
| Likely | 75 (6.5) |
| Possible | 51 (4.4) |
| Unknown | 136 (11.7) |
| None | 652 (56.1) |
| Previous cardiac surgeries, n (%) | |
| CABG | 37 (3.2) |
| AVR | 64 (5.5) |
| MVR | 13 (1.1) |
| CABG + AVR | 17 (1.4) |
| AVR + MVR | 2 (0.02) |
| CABG + AVR + MVR | 2 (0.02) |
| Hypertension, n (%) | 716 (61.6) |
| Diabetes mellitus, n (%) | 178 (15.3) |
| Endpoints, n (%) | |
| Acute type A dissection | 120 (10.3) |
| Rupture | 2 (0.2) |
| Ascending aorta death | 8 (0.7) |
| Composite endpoint 1 | 130 (11.2) |
| Unknown or other cause of death | 119 (10.2) |
| Composite endpoint 2 | 249 (21.4) |
| Surgery, pre-emptive | 545 (46.9) |
| Total number of patients | 1162 |
| Males, n (%) | 791 (68.1) |
| Females, n (%) | 371 (31.9) |
| Age (years), mean ± SD | 70.2 ± 13.5 |
| Body surface area (m2), mean ± SD | 1.99 ± 0.28 |
| Bicuspid, n (%) | 257 (22.1) |
| Marfan—connective tissue disorders, n (%) | 36 (3.1) |
| Family history | |
| Proven | 248 (21.3) |
| Likely | 75 (6.5) |
| Possible | 51 (4.4) |
| Unknown | 136 (11.7) |
| None | 652 (56.1) |
| Previous cardiac surgeries, n (%) | |
| CABG | 37 (3.2) |
| AVR | 64 (5.5) |
| MVR | 13 (1.1) |
| CABG + AVR | 17 (1.4) |
| AVR + MVR | 2 (0.02) |
| CABG + AVR + MVR | 2 (0.02) |
| Hypertension, n (%) | 716 (61.6) |
| Diabetes mellitus, n (%) | 178 (15.3) |
| Endpoints, n (%) | |
| Acute type A dissection | 120 (10.3) |
| Rupture | 2 (0.2) |
| Ascending aorta death | 8 (0.7) |
| Composite endpoint 1 | 130 (11.2) |
| Unknown or other cause of death | 119 (10.2) |
| Composite endpoint 2 | 249 (21.4) |
| Surgery, pre-emptive | 545 (46.9) |
Composite endpoint 1 consists of acute type A dissection, rupture and ascending aorta-related death; and Composite endpoint 2 of acute type A dissection, rupture and all cause death data are provided as mean ± SD or number (percentage).
AVR: aortic valve replacement; CABG: coronary artery bypass grafting; MVR: mitral valve replacement; SD: standard deviation.
This PDF is available to Subscribers Only
View Article Abstract & Purchase OptionsFor full access to this pdf, sign in to an existing account, or purchase an annual subscription.
