Table 2.

Lung cancer risk among participants in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study

Explanatory variablesRR (95% CI)
Smoking behavior
 Not smoking1.00 (Referent)
 Trying to quita1.09 (0.80 to 1.47)
 Smokingb1.14 (1.04 to 1.25)
Baseline cigarettes per dayc1.13 (1.07 to 1.19)
Rate of change cigarettes per dayd1.25 (1.11 to 1.40)
Intervention
 Placebo1.00 (Referent)
 Alpha-tocopherol1.06 (0.78 to 1.43)
 Beta-carotene1.15 (0.85 to 1.55)
 Alpha-tocopherol plus beta-carotene1.09 (0.80 to 1.49)
Education
 High school or less1.00 (Referent)
 College0.73 (0.59 to 0.91)
 College graduate0.40 (0.20 to 0.78)
Age, y1.15 (1.12 to 1.17)
Age at smoking initiation, y0.91 (0.88 to 0.94)
Explanatory variablesRR (95% CI)
Smoking behavior
 Not smoking1.00 (Referent)
 Trying to quita1.09 (0.80 to 1.47)
 Smokingb1.14 (1.04 to 1.25)
Baseline cigarettes per dayc1.13 (1.07 to 1.19)
Rate of change cigarettes per dayd1.25 (1.11 to 1.40)
Intervention
 Placebo1.00 (Referent)
 Alpha-tocopherol1.06 (0.78 to 1.43)
 Beta-carotene1.15 (0.85 to 1.55)
 Alpha-tocopherol plus beta-carotene1.09 (0.80 to 1.49)
Education
 High school or less1.00 (Referent)
 College0.73 (0.59 to 0.91)
 College graduate0.40 (0.20 to 0.78)
Age, y1.15 (1.12 to 1.17)
Age at smoking initiation, y0.91 (0.88 to 0.94)
a

Risk ratio corresponds to a change of 20% in the proportion of visits when men were trying to quit. CI = confidence interval; RR = risk ratio.

b

Risk ratio corresponds to a change of 20% in the proportion of visits when men smoked.

c

Risk ratio corresponds to an increase of 5 cigarettes per day in the baseline smoking intensity.

d

Risk ratio corresponds to an increase in smoking intensity at a rate of 5 cigarettes per day per intervention year.

Table 2.

Lung cancer risk among participants in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study

Explanatory variablesRR (95% CI)
Smoking behavior
 Not smoking1.00 (Referent)
 Trying to quita1.09 (0.80 to 1.47)
 Smokingb1.14 (1.04 to 1.25)
Baseline cigarettes per dayc1.13 (1.07 to 1.19)
Rate of change cigarettes per dayd1.25 (1.11 to 1.40)
Intervention
 Placebo1.00 (Referent)
 Alpha-tocopherol1.06 (0.78 to 1.43)
 Beta-carotene1.15 (0.85 to 1.55)
 Alpha-tocopherol plus beta-carotene1.09 (0.80 to 1.49)
Education
 High school or less1.00 (Referent)
 College0.73 (0.59 to 0.91)
 College graduate0.40 (0.20 to 0.78)
Age, y1.15 (1.12 to 1.17)
Age at smoking initiation, y0.91 (0.88 to 0.94)
Explanatory variablesRR (95% CI)
Smoking behavior
 Not smoking1.00 (Referent)
 Trying to quita1.09 (0.80 to 1.47)
 Smokingb1.14 (1.04 to 1.25)
Baseline cigarettes per dayc1.13 (1.07 to 1.19)
Rate of change cigarettes per dayd1.25 (1.11 to 1.40)
Intervention
 Placebo1.00 (Referent)
 Alpha-tocopherol1.06 (0.78 to 1.43)
 Beta-carotene1.15 (0.85 to 1.55)
 Alpha-tocopherol plus beta-carotene1.09 (0.80 to 1.49)
Education
 High school or less1.00 (Referent)
 College0.73 (0.59 to 0.91)
 College graduate0.40 (0.20 to 0.78)
Age, y1.15 (1.12 to 1.17)
Age at smoking initiation, y0.91 (0.88 to 0.94)
a

Risk ratio corresponds to a change of 20% in the proportion of visits when men were trying to quit. CI = confidence interval; RR = risk ratio.

b

Risk ratio corresponds to a change of 20% in the proportion of visits when men smoked.

c

Risk ratio corresponds to an increase of 5 cigarettes per day in the baseline smoking intensity.

d

Risk ratio corresponds to an increase in smoking intensity at a rate of 5 cigarettes per day per intervention year.

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