| Regions of high-grade glioma morphology (%: variant allelic fraction) . | Regions of epithelial differentiation (%: variant allelic fraction) . |
|---|---|
| TERT variant (c.-124C > T), 36% | TERT variant (c.-124C > T), 52% |
| CDK4 amplification (21.0 copies) | CDK4 amplification (25.0 copies) |
| Gain of chromosome 7 | Gain of chromosome 7 |
| Loss of chromosome 10 | Loss of chromosome 10 |
| EGFR variant (c.2320G > A), 24% | No EGFR variant |
| EGFR amplification (73.0 copies) | No EGFR amplification |
| MDM2 amplification (35.0 copies) | No MDM2 amplification |
| No TP53 variant | TP53 variant (c.724T > A), 61% |
| No fusion transcript | FGFR3::TACC3 fusion |
| Methylation class “glioblastoma, IDH wild type” (0.99) | Methylation class “brain” (0.96), subclass “glioblastoma” (0.8) |
| Regions of high-grade glioma morphology (%: variant allelic fraction) . | Regions of epithelial differentiation (%: variant allelic fraction) . |
|---|---|
| TERT variant (c.-124C > T), 36% | TERT variant (c.-124C > T), 52% |
| CDK4 amplification (21.0 copies) | CDK4 amplification (25.0 copies) |
| Gain of chromosome 7 | Gain of chromosome 7 |
| Loss of chromosome 10 | Loss of chromosome 10 |
| EGFR variant (c.2320G > A), 24% | No EGFR variant |
| EGFR amplification (73.0 copies) | No EGFR amplification |
| MDM2 amplification (35.0 copies) | No MDM2 amplification |
| No TP53 variant | TP53 variant (c.724T > A), 61% |
| No fusion transcript | FGFR3::TACC3 fusion |
| Methylation class “glioblastoma, IDH wild type” (0.99) | Methylation class “brain” (0.96), subclass “glioblastoma” (0.8) |
| Regions of high-grade glioma morphology (%: variant allelic fraction) . | Regions of epithelial differentiation (%: variant allelic fraction) . |
|---|---|
| TERT variant (c.-124C > T), 36% | TERT variant (c.-124C > T), 52% |
| CDK4 amplification (21.0 copies) | CDK4 amplification (25.0 copies) |
| Gain of chromosome 7 | Gain of chromosome 7 |
| Loss of chromosome 10 | Loss of chromosome 10 |
| EGFR variant (c.2320G > A), 24% | No EGFR variant |
| EGFR amplification (73.0 copies) | No EGFR amplification |
| MDM2 amplification (35.0 copies) | No MDM2 amplification |
| No TP53 variant | TP53 variant (c.724T > A), 61% |
| No fusion transcript | FGFR3::TACC3 fusion |
| Methylation class “glioblastoma, IDH wild type” (0.99) | Methylation class “brain” (0.96), subclass “glioblastoma” (0.8) |
| Regions of high-grade glioma morphology (%: variant allelic fraction) . | Regions of epithelial differentiation (%: variant allelic fraction) . |
|---|---|
| TERT variant (c.-124C > T), 36% | TERT variant (c.-124C > T), 52% |
| CDK4 amplification (21.0 copies) | CDK4 amplification (25.0 copies) |
| Gain of chromosome 7 | Gain of chromosome 7 |
| Loss of chromosome 10 | Loss of chromosome 10 |
| EGFR variant (c.2320G > A), 24% | No EGFR variant |
| EGFR amplification (73.0 copies) | No EGFR amplification |
| MDM2 amplification (35.0 copies) | No MDM2 amplification |
| No TP53 variant | TP53 variant (c.724T > A), 61% |
| No fusion transcript | FGFR3::TACC3 fusion |
| Methylation class “glioblastoma, IDH wild type” (0.99) | Methylation class “brain” (0.96), subclass “glioblastoma” (0.8) |
This PDF is available to Subscribers Only
View Article Abstract & Purchase OptionsFor full access to this pdf, sign in to an existing account, or purchase an annual subscription.
