Table 3.

Multivariate Model for Overall Survival From Initiation of Pulsed Reduced-Dose Rate

VariableHR95% CIP-value
KPS (< 80, n = 9; vs. ≥ 80, n = 49)163.9–65.6<.001
1p191 codeletion status (Co-deleted, n = 16; vs. non-co-deleted, n = 20)0.30.1–0.7.004
Histologic grade transformation (remain grade 2, n = 18; vs. transformed to grade 3 or 4, n = 40)4.21.7–10.4.002
Time from diagnosis to first progression (< 5 years, n = 28; vs. ≥ 5 years, n = 30)3.11.3–7.1.008
VariableHR95% CIP-value
KPS (< 80, n = 9; vs. ≥ 80, n = 49)163.9–65.6<.001
1p191 codeletion status (Co-deleted, n = 16; vs. non-co-deleted, n = 20)0.30.1–0.7.004
Histologic grade transformation (remain grade 2, n = 18; vs. transformed to grade 3 or 4, n = 40)4.21.7–10.4.002
Time from diagnosis to first progression (< 5 years, n = 28; vs. ≥ 5 years, n = 30)3.11.3–7.1.008
Table 3.

Multivariate Model for Overall Survival From Initiation of Pulsed Reduced-Dose Rate

VariableHR95% CIP-value
KPS (< 80, n = 9; vs. ≥ 80, n = 49)163.9–65.6<.001
1p191 codeletion status (Co-deleted, n = 16; vs. non-co-deleted, n = 20)0.30.1–0.7.004
Histologic grade transformation (remain grade 2, n = 18; vs. transformed to grade 3 or 4, n = 40)4.21.7–10.4.002
Time from diagnosis to first progression (< 5 years, n = 28; vs. ≥ 5 years, n = 30)3.11.3–7.1.008
VariableHR95% CIP-value
KPS (< 80, n = 9; vs. ≥ 80, n = 49)163.9–65.6<.001
1p191 codeletion status (Co-deleted, n = 16; vs. non-co-deleted, n = 20)0.30.1–0.7.004
Histologic grade transformation (remain grade 2, n = 18; vs. transformed to grade 3 or 4, n = 40)4.21.7–10.4.002
Time from diagnosis to first progression (< 5 years, n = 28; vs. ≥ 5 years, n = 30)3.11.3–7.1.008
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