Demographic and Volume Data of the 2 Different Clusters in the Training and Test Datasets. Uncorrected P-Values. All significant values are bold and highlighted with an asterisk (*).
| Parameter . | . | Training Set . | Test Set . | ||||
|---|---|---|---|---|---|---|---|
| . | Cluster 1 . | Cluster 2 . | P-value . | Cluster 1 . | Cluster 2 . | P-value . | |
| Total no. of patients . | . | 96 . | 135 . | NA . | 17 . | 41 . | NA . |
| Sex [n (%)] | Female | 41 (43) | 65 (48) | 0.41 | 4 (24) | 19 (46) | 0.12 |
| Age [y] | Mean ± std. | 60 ± 15 | 62 ± 12 | 0.47 | 63 ± 12 | 62 ± 10 | 0.77 |
| MGMT status [n (%)] | Methylated | 35 (36) | 64 (47) | 0.1 | 6 (35) | 15 (37) | 0.93 |
| Preoperative ECOG [n (%)] | ECOG ≤ 2 | 91 (95) | 130 (96) | 0.58 | 17 (100) | 37 (90) | 0.18 |
| First-line therapy [n (%)] | Radiochemo therapy | 63 (66) | 86 (64) | 0.13 | 10 (59) | 20 (49) | 0.55 |
| Radiotherapy alone | 16 (17) | 18 (13) | 3 (18) | 6 (15) | |||
| Chemotherapy alone | 4 (4) | 6 (4) | 2 (12) | 2 (5) | |||
| Resection alone | 4 (4) | 1 (1) | 0 (0) | 0 (0) | |||
| BSC | 1 (1) | 0 (0) | 0 (0) | 1 (2) | |||
| Missing | 8 (8) | 24 (18) | 2 (12) | 12 (29) | |||
| Tumor volume [cm3 (mean ± std.)] | Whole volume | 92 ± 58 | 75 ± 59 | 0.02* | 92 ± 67 | 78 ± 47 | 0.61 |
| Edema volume | 65 ± 44 | 49 ± 41 | 0.003* | 70 ± 51 | 49 ± 34 | 0.19 | |
| Contrast volume | 18 ± 18 | 20 ± 21 | 0.27 | 14 ± 15 | 20 ± 23 | 0.19 | |
| Necrosis volume | 9.4 ± 12 | 6.7 ± 10 | 0.45 | 8.3 ± 14 | 8.3 ± 13 | 0.5 | |
| Parameter . | . | Training Set . | Test Set . | ||||
|---|---|---|---|---|---|---|---|
| . | Cluster 1 . | Cluster 2 . | P-value . | Cluster 1 . | Cluster 2 . | P-value . | |
| Total no. of patients . | . | 96 . | 135 . | NA . | 17 . | 41 . | NA . |
| Sex [n (%)] | Female | 41 (43) | 65 (48) | 0.41 | 4 (24) | 19 (46) | 0.12 |
| Age [y] | Mean ± std. | 60 ± 15 | 62 ± 12 | 0.47 | 63 ± 12 | 62 ± 10 | 0.77 |
| MGMT status [n (%)] | Methylated | 35 (36) | 64 (47) | 0.1 | 6 (35) | 15 (37) | 0.93 |
| Preoperative ECOG [n (%)] | ECOG ≤ 2 | 91 (95) | 130 (96) | 0.58 | 17 (100) | 37 (90) | 0.18 |
| First-line therapy [n (%)] | Radiochemo therapy | 63 (66) | 86 (64) | 0.13 | 10 (59) | 20 (49) | 0.55 |
| Radiotherapy alone | 16 (17) | 18 (13) | 3 (18) | 6 (15) | |||
| Chemotherapy alone | 4 (4) | 6 (4) | 2 (12) | 2 (5) | |||
| Resection alone | 4 (4) | 1 (1) | 0 (0) | 0 (0) | |||
| BSC | 1 (1) | 0 (0) | 0 (0) | 1 (2) | |||
| Missing | 8 (8) | 24 (18) | 2 (12) | 12 (29) | |||
| Tumor volume [cm3 (mean ± std.)] | Whole volume | 92 ± 58 | 75 ± 59 | 0.02* | 92 ± 67 | 78 ± 47 | 0.61 |
| Edema volume | 65 ± 44 | 49 ± 41 | 0.003* | 70 ± 51 | 49 ± 34 | 0.19 | |
| Contrast volume | 18 ± 18 | 20 ± 21 | 0.27 | 14 ± 15 | 20 ± 23 | 0.19 | |
| Necrosis volume | 9.4 ± 12 | 6.7 ± 10 | 0.45 | 8.3 ± 14 | 8.3 ± 13 | 0.5 | |
Demographic and Volume Data of the 2 Different Clusters in the Training and Test Datasets. Uncorrected P-Values. All significant values are bold and highlighted with an asterisk (*).
| Parameter . | . | Training Set . | Test Set . | ||||
|---|---|---|---|---|---|---|---|
| . | Cluster 1 . | Cluster 2 . | P-value . | Cluster 1 . | Cluster 2 . | P-value . | |
| Total no. of patients . | . | 96 . | 135 . | NA . | 17 . | 41 . | NA . |
| Sex [n (%)] | Female | 41 (43) | 65 (48) | 0.41 | 4 (24) | 19 (46) | 0.12 |
| Age [y] | Mean ± std. | 60 ± 15 | 62 ± 12 | 0.47 | 63 ± 12 | 62 ± 10 | 0.77 |
| MGMT status [n (%)] | Methylated | 35 (36) | 64 (47) | 0.1 | 6 (35) | 15 (37) | 0.93 |
| Preoperative ECOG [n (%)] | ECOG ≤ 2 | 91 (95) | 130 (96) | 0.58 | 17 (100) | 37 (90) | 0.18 |
| First-line therapy [n (%)] | Radiochemo therapy | 63 (66) | 86 (64) | 0.13 | 10 (59) | 20 (49) | 0.55 |
| Radiotherapy alone | 16 (17) | 18 (13) | 3 (18) | 6 (15) | |||
| Chemotherapy alone | 4 (4) | 6 (4) | 2 (12) | 2 (5) | |||
| Resection alone | 4 (4) | 1 (1) | 0 (0) | 0 (0) | |||
| BSC | 1 (1) | 0 (0) | 0 (0) | 1 (2) | |||
| Missing | 8 (8) | 24 (18) | 2 (12) | 12 (29) | |||
| Tumor volume [cm3 (mean ± std.)] | Whole volume | 92 ± 58 | 75 ± 59 | 0.02* | 92 ± 67 | 78 ± 47 | 0.61 |
| Edema volume | 65 ± 44 | 49 ± 41 | 0.003* | 70 ± 51 | 49 ± 34 | 0.19 | |
| Contrast volume | 18 ± 18 | 20 ± 21 | 0.27 | 14 ± 15 | 20 ± 23 | 0.19 | |
| Necrosis volume | 9.4 ± 12 | 6.7 ± 10 | 0.45 | 8.3 ± 14 | 8.3 ± 13 | 0.5 | |
| Parameter . | . | Training Set . | Test Set . | ||||
|---|---|---|---|---|---|---|---|
| . | Cluster 1 . | Cluster 2 . | P-value . | Cluster 1 . | Cluster 2 . | P-value . | |
| Total no. of patients . | . | 96 . | 135 . | NA . | 17 . | 41 . | NA . |
| Sex [n (%)] | Female | 41 (43) | 65 (48) | 0.41 | 4 (24) | 19 (46) | 0.12 |
| Age [y] | Mean ± std. | 60 ± 15 | 62 ± 12 | 0.47 | 63 ± 12 | 62 ± 10 | 0.77 |
| MGMT status [n (%)] | Methylated | 35 (36) | 64 (47) | 0.1 | 6 (35) | 15 (37) | 0.93 |
| Preoperative ECOG [n (%)] | ECOG ≤ 2 | 91 (95) | 130 (96) | 0.58 | 17 (100) | 37 (90) | 0.18 |
| First-line therapy [n (%)] | Radiochemo therapy | 63 (66) | 86 (64) | 0.13 | 10 (59) | 20 (49) | 0.55 |
| Radiotherapy alone | 16 (17) | 18 (13) | 3 (18) | 6 (15) | |||
| Chemotherapy alone | 4 (4) | 6 (4) | 2 (12) | 2 (5) | |||
| Resection alone | 4 (4) | 1 (1) | 0 (0) | 0 (0) | |||
| BSC | 1 (1) | 0 (0) | 0 (0) | 1 (2) | |||
| Missing | 8 (8) | 24 (18) | 2 (12) | 12 (29) | |||
| Tumor volume [cm3 (mean ± std.)] | Whole volume | 92 ± 58 | 75 ± 59 | 0.02* | 92 ± 67 | 78 ± 47 | 0.61 |
| Edema volume | 65 ± 44 | 49 ± 41 | 0.003* | 70 ± 51 | 49 ± 34 | 0.19 | |
| Contrast volume | 18 ± 18 | 20 ± 21 | 0.27 | 14 ± 15 | 20 ± 23 | 0.19 | |
| Necrosis volume | 9.4 ± 12 | 6.7 ± 10 | 0.45 | 8.3 ± 14 | 8.3 ± 13 | 0.5 | |
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