Crude odds ratio and risk ratio of early anti-TNF therapy for sustained steroid-free mild or inactive disease without treatment intensification at one year by paediatric Crohn’s disease risk groups.
| Subgroup . | OR . | 95% CI . | p-value . | RR . | 95% CI . | p-value . |
|---|---|---|---|---|---|---|
| Mild/inactive disease at diagnosis | 3.86 | 1.27–11.72 | 0.02 | 2.91 | 0.92–9.11 | 0.07 |
| Moderate/severe disease at diagnosis | 7.22 | 3.45–15.13 | <0.001 | 5.50 | 2.51–12.05 | <0.001 |
| No POPO | 4.63 | 1.03–20.87 | 0.046 | 3.41 | 0.54–21.7 | 0.19 |
| Any POPO | 6.66 | 3.48–12.72 | <0.001 | 5.05 | 2.45–10.43 | <0.001 |
| Subgroup . | OR . | 95% CI . | p-value . | RR . | 95% CI . | p-value . |
|---|---|---|---|---|---|---|
| Mild/inactive disease at diagnosis | 3.86 | 1.27–11.72 | 0.02 | 2.91 | 0.92–9.11 | 0.07 |
| Moderate/severe disease at diagnosis | 7.22 | 3.45–15.13 | <0.001 | 5.50 | 2.51–12.05 | <0.001 |
| No POPO | 4.63 | 1.03–20.87 | 0.046 | 3.41 | 0.54–21.7 | 0.19 |
| Any POPO | 6.66 | 3.48–12.72 | <0.001 | 5.05 | 2.45–10.43 | <0.001 |
TNF, tumour necrosis factor; OR, odds ratio; CI, confidence interval; RR, relative risk; POPO, predictor of poor outcome.
Crude odds ratio and risk ratio of early anti-TNF therapy for sustained steroid-free mild or inactive disease without treatment intensification at one year by paediatric Crohn’s disease risk groups.
| Subgroup . | OR . | 95% CI . | p-value . | RR . | 95% CI . | p-value . |
|---|---|---|---|---|---|---|
| Mild/inactive disease at diagnosis | 3.86 | 1.27–11.72 | 0.02 | 2.91 | 0.92–9.11 | 0.07 |
| Moderate/severe disease at diagnosis | 7.22 | 3.45–15.13 | <0.001 | 5.50 | 2.51–12.05 | <0.001 |
| No POPO | 4.63 | 1.03–20.87 | 0.046 | 3.41 | 0.54–21.7 | 0.19 |
| Any POPO | 6.66 | 3.48–12.72 | <0.001 | 5.05 | 2.45–10.43 | <0.001 |
| Subgroup . | OR . | 95% CI . | p-value . | RR . | 95% CI . | p-value . |
|---|---|---|---|---|---|---|
| Mild/inactive disease at diagnosis | 3.86 | 1.27–11.72 | 0.02 | 2.91 | 0.92–9.11 | 0.07 |
| Moderate/severe disease at diagnosis | 7.22 | 3.45–15.13 | <0.001 | 5.50 | 2.51–12.05 | <0.001 |
| No POPO | 4.63 | 1.03–20.87 | 0.046 | 3.41 | 0.54–21.7 | 0.19 |
| Any POPO | 6.66 | 3.48–12.72 | <0.001 | 5.05 | 2.45–10.43 | <0.001 |
TNF, tumour necrosis factor; OR, odds ratio; CI, confidence interval; RR, relative risk; POPO, predictor of poor outcome.
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