Characteristics of 23 Johns Hopkins Hospital Emergency Department Patients With High-Titer Syphilis Infection (Rapid Plasma Reagin Titer ≥1:8) in a Seroprevalence Study of 1951 Patients, January–February 2022
| Subject . | Woman of Reproductive Age . | Has PCP . | HIV Status . | RPR Titer . | Chief Complaint . | ED Primary Diagnosis . |
|---|---|---|---|---|---|---|
| 1 | Yes | Yes | Positive | 1:8 | Not STI/syphilis-related | Non-syphilis |
| 2 | No | Yes | Negative | 1:8 | Not STI/syphilis-related | Non-syphilis |
| 3 | NA | No | Negative | 1:8 | Not STI/syphilis-related | Non-syphilis |
| 4 | NA | Yes | Positive | 1:8 | Not STI/syphilis-related | Non-syphilis |
| 5 | NA | No | Negative | 1:8 | Not STI/syphilis-related | Non-syphilis |
| 6 | NA | No | Negative | 1:8 | Not STI/syphilis-related | Non-syphilis |
| 7 | NA | No | Positive | 1:16 | Not STI/syphilis-related | Non-syphilis |
| 8 | NA | No | Negative | 1:16 | Not STI/syphilis-related | Non-syphilis |
| 9 | NA | Yes | Negative | 1:16 | Not STI/syphilis-related | Non-syphilis |
| 10 | NA | No | Negative | 1:16 | Not STI/syphilis-related | Non-syphilis |
| 11 | NA | No | Negative | 1:16 | Possible STI/syphilis-related | Non-syphilis |
| 12 | Yes | Yes | Negative | 1:32 | Possible STI/syphilis-related | Exposure to syphilis |
| 13 | NA | No | Positive | 1:32 | Not STI/syphilis-related | Non-syphilis |
| 14 | Yes | No | Negative | 1:64 | Not STI/syphilis-related | Non-syphilis |
| 15 | NA | No | Negative | 1:64 | Not STI/syphilis-related | Non-syphilis |
| 16 | NA | No | Negative | 1:64 | Possible STI/syphilis-related | Non-syphilis |
| 17 | NA | No | Negative | 1:128 | Not STI/syphilis-related | Non-syphilis |
| 18 | Yes | No | Negative | 1:128 | Not STI/syphilis-related | Neurosyphilis |
| 19 | Yes | No | Negative | 1:128 | Not STI/syphilis-related | Non-syphilis |
| 20 | Yes | No | Negative | 1:128 | Not STI/syphilis-related | Non-syphilis |
| 21 | NA | No | Positive | 1:256 | Not STI/syphilis-related | Non-syphilis |
| 22 | Yes | No | Negative | 1:256 | Not STI/syphilis-related | Non-syphilis |
| 23 | Yes | No | Negative | 1:256 | Not STI/syphilis-related | Non-syphilis |
| Subject . | Woman of Reproductive Age . | Has PCP . | HIV Status . | RPR Titer . | Chief Complaint . | ED Primary Diagnosis . |
|---|---|---|---|---|---|---|
| 1 | Yes | Yes | Positive | 1:8 | Not STI/syphilis-related | Non-syphilis |
| 2 | No | Yes | Negative | 1:8 | Not STI/syphilis-related | Non-syphilis |
| 3 | NA | No | Negative | 1:8 | Not STI/syphilis-related | Non-syphilis |
| 4 | NA | Yes | Positive | 1:8 | Not STI/syphilis-related | Non-syphilis |
| 5 | NA | No | Negative | 1:8 | Not STI/syphilis-related | Non-syphilis |
| 6 | NA | No | Negative | 1:8 | Not STI/syphilis-related | Non-syphilis |
| 7 | NA | No | Positive | 1:16 | Not STI/syphilis-related | Non-syphilis |
| 8 | NA | No | Negative | 1:16 | Not STI/syphilis-related | Non-syphilis |
| 9 | NA | Yes | Negative | 1:16 | Not STI/syphilis-related | Non-syphilis |
| 10 | NA | No | Negative | 1:16 | Not STI/syphilis-related | Non-syphilis |
| 11 | NA | No | Negative | 1:16 | Possible STI/syphilis-related | Non-syphilis |
| 12 | Yes | Yes | Negative | 1:32 | Possible STI/syphilis-related | Exposure to syphilis |
| 13 | NA | No | Positive | 1:32 | Not STI/syphilis-related | Non-syphilis |
| 14 | Yes | No | Negative | 1:64 | Not STI/syphilis-related | Non-syphilis |
| 15 | NA | No | Negative | 1:64 | Not STI/syphilis-related | Non-syphilis |
| 16 | NA | No | Negative | 1:64 | Possible STI/syphilis-related | Non-syphilis |
| 17 | NA | No | Negative | 1:128 | Not STI/syphilis-related | Non-syphilis |
| 18 | Yes | No | Negative | 1:128 | Not STI/syphilis-related | Neurosyphilis |
| 19 | Yes | No | Negative | 1:128 | Not STI/syphilis-related | Non-syphilis |
| 20 | Yes | No | Negative | 1:128 | Not STI/syphilis-related | Non-syphilis |
| 21 | NA | No | Positive | 1:256 | Not STI/syphilis-related | Non-syphilis |
| 22 | Yes | No | Negative | 1:256 | Not STI/syphilis-related | Non-syphilis |
| 23 | Yes | No | Negative | 1:256 | Not STI/syphilis-related | Non-syphilis |
Abbreviations: ED, emergency department; HIV, human immunodeficiency virus; NA, not applicable, patient was male; PCP, primary care physician; RPR, rapid plasma reagin; STI, sexually transmitted infection. Bold text in the table indicates which of the screening variables would have applied to identify this patient for syphilis screening. Bold and italic text in the table indicates possible syphilis-related ED chief complaint and syphilis-related ED diagnosis.
Characteristics of 23 Johns Hopkins Hospital Emergency Department Patients With High-Titer Syphilis Infection (Rapid Plasma Reagin Titer ≥1:8) in a Seroprevalence Study of 1951 Patients, January–February 2022
| Subject . | Woman of Reproductive Age . | Has PCP . | HIV Status . | RPR Titer . | Chief Complaint . | ED Primary Diagnosis . |
|---|---|---|---|---|---|---|
| 1 | Yes | Yes | Positive | 1:8 | Not STI/syphilis-related | Non-syphilis |
| 2 | No | Yes | Negative | 1:8 | Not STI/syphilis-related | Non-syphilis |
| 3 | NA | No | Negative | 1:8 | Not STI/syphilis-related | Non-syphilis |
| 4 | NA | Yes | Positive | 1:8 | Not STI/syphilis-related | Non-syphilis |
| 5 | NA | No | Negative | 1:8 | Not STI/syphilis-related | Non-syphilis |
| 6 | NA | No | Negative | 1:8 | Not STI/syphilis-related | Non-syphilis |
| 7 | NA | No | Positive | 1:16 | Not STI/syphilis-related | Non-syphilis |
| 8 | NA | No | Negative | 1:16 | Not STI/syphilis-related | Non-syphilis |
| 9 | NA | Yes | Negative | 1:16 | Not STI/syphilis-related | Non-syphilis |
| 10 | NA | No | Negative | 1:16 | Not STI/syphilis-related | Non-syphilis |
| 11 | NA | No | Negative | 1:16 | Possible STI/syphilis-related | Non-syphilis |
| 12 | Yes | Yes | Negative | 1:32 | Possible STI/syphilis-related | Exposure to syphilis |
| 13 | NA | No | Positive | 1:32 | Not STI/syphilis-related | Non-syphilis |
| 14 | Yes | No | Negative | 1:64 | Not STI/syphilis-related | Non-syphilis |
| 15 | NA | No | Negative | 1:64 | Not STI/syphilis-related | Non-syphilis |
| 16 | NA | No | Negative | 1:64 | Possible STI/syphilis-related | Non-syphilis |
| 17 | NA | No | Negative | 1:128 | Not STI/syphilis-related | Non-syphilis |
| 18 | Yes | No | Negative | 1:128 | Not STI/syphilis-related | Neurosyphilis |
| 19 | Yes | No | Negative | 1:128 | Not STI/syphilis-related | Non-syphilis |
| 20 | Yes | No | Negative | 1:128 | Not STI/syphilis-related | Non-syphilis |
| 21 | NA | No | Positive | 1:256 | Not STI/syphilis-related | Non-syphilis |
| 22 | Yes | No | Negative | 1:256 | Not STI/syphilis-related | Non-syphilis |
| 23 | Yes | No | Negative | 1:256 | Not STI/syphilis-related | Non-syphilis |
| Subject . | Woman of Reproductive Age . | Has PCP . | HIV Status . | RPR Titer . | Chief Complaint . | ED Primary Diagnosis . |
|---|---|---|---|---|---|---|
| 1 | Yes | Yes | Positive | 1:8 | Not STI/syphilis-related | Non-syphilis |
| 2 | No | Yes | Negative | 1:8 | Not STI/syphilis-related | Non-syphilis |
| 3 | NA | No | Negative | 1:8 | Not STI/syphilis-related | Non-syphilis |
| 4 | NA | Yes | Positive | 1:8 | Not STI/syphilis-related | Non-syphilis |
| 5 | NA | No | Negative | 1:8 | Not STI/syphilis-related | Non-syphilis |
| 6 | NA | No | Negative | 1:8 | Not STI/syphilis-related | Non-syphilis |
| 7 | NA | No | Positive | 1:16 | Not STI/syphilis-related | Non-syphilis |
| 8 | NA | No | Negative | 1:16 | Not STI/syphilis-related | Non-syphilis |
| 9 | NA | Yes | Negative | 1:16 | Not STI/syphilis-related | Non-syphilis |
| 10 | NA | No | Negative | 1:16 | Not STI/syphilis-related | Non-syphilis |
| 11 | NA | No | Negative | 1:16 | Possible STI/syphilis-related | Non-syphilis |
| 12 | Yes | Yes | Negative | 1:32 | Possible STI/syphilis-related | Exposure to syphilis |
| 13 | NA | No | Positive | 1:32 | Not STI/syphilis-related | Non-syphilis |
| 14 | Yes | No | Negative | 1:64 | Not STI/syphilis-related | Non-syphilis |
| 15 | NA | No | Negative | 1:64 | Not STI/syphilis-related | Non-syphilis |
| 16 | NA | No | Negative | 1:64 | Possible STI/syphilis-related | Non-syphilis |
| 17 | NA | No | Negative | 1:128 | Not STI/syphilis-related | Non-syphilis |
| 18 | Yes | No | Negative | 1:128 | Not STI/syphilis-related | Neurosyphilis |
| 19 | Yes | No | Negative | 1:128 | Not STI/syphilis-related | Non-syphilis |
| 20 | Yes | No | Negative | 1:128 | Not STI/syphilis-related | Non-syphilis |
| 21 | NA | No | Positive | 1:256 | Not STI/syphilis-related | Non-syphilis |
| 22 | Yes | No | Negative | 1:256 | Not STI/syphilis-related | Non-syphilis |
| 23 | Yes | No | Negative | 1:256 | Not STI/syphilis-related | Non-syphilis |
Abbreviations: ED, emergency department; HIV, human immunodeficiency virus; NA, not applicable, patient was male; PCP, primary care physician; RPR, rapid plasma reagin; STI, sexually transmitted infection. Bold text in the table indicates which of the screening variables would have applied to identify this patient for syphilis screening. Bold and italic text in the table indicates possible syphilis-related ED chief complaint and syphilis-related ED diagnosis.
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