Correlation Coefficients Between Different Viral Biomarkers in 96 Patients Receiving Antiviral Prophylaxis
| . | pgRNA, log10 copies/mL . | HBcrAg, log10 U/mL . | HBsAg, log10 IU/mL . | HBeAg, log10 PEIU/mL . |
|---|---|---|---|---|
| Baseline (n = 96) | ||||
| HBV DNA, log10 IU/mL | 0.353 (P < .000) | 0.324 (P = .001) | 0.314 (P = .002) | 0.207 (P = .043) |
| pgRNA, log10 copies/mL | … | 0.523 (P < .000) | 0.456 (P < .000) | 0.259 (P = .011) |
| HBcrAg, log10 U/mL | … | … | 0.490 (P < .000) | 0.513 (P < .000) |
| HBsAg, log10 IU/mL | … | … | … | 0.538 (P < .000) |
| Near delivery (n = 96) | ||||
| HBV DNA, log10 IU/mL | 0.300 (P = .003) | 0.182 (P = .076) | 0.374 (P < .000) | 0.263 (P = .010) |
| pgRNA, log10 copies/mL | … | 0.652 (P < .000) | 0.581 (P < .000) | 0.471 (P < .000) |
| HBcrAg, log10 U/mL | … | … | 0.475 (P < .000) | 0.660 (P < .000) |
| HBsAg, log10 IU/mL | … | … | … | 0.583 (P < .000) |
| Postpartum (n = 39) | ||||
| HBV DNA, log10 IU/mL | 0.332 (P = .039) | 0.173 (P = .291) | 0.332 (P = .039) | 0.332 (P = .039) |
| pgRNA, log10 copies/mL | … | 0.799 (P < .000) | 0.810 (P < .000) | 0.636 (P < .000) |
| HBcrAg, log10 U/mL | … | … | 0.627 (P < .000) | 0.739 (P < .000) |
| HBsAg, log10 IU/mL | … | … | … | 0.627 (P < .000) |
| . | pgRNA, log10 copies/mL . | HBcrAg, log10 U/mL . | HBsAg, log10 IU/mL . | HBeAg, log10 PEIU/mL . |
|---|---|---|---|---|
| Baseline (n = 96) | ||||
| HBV DNA, log10 IU/mL | 0.353 (P < .000) | 0.324 (P = .001) | 0.314 (P = .002) | 0.207 (P = .043) |
| pgRNA, log10 copies/mL | … | 0.523 (P < .000) | 0.456 (P < .000) | 0.259 (P = .011) |
| HBcrAg, log10 U/mL | … | … | 0.490 (P < .000) | 0.513 (P < .000) |
| HBsAg, log10 IU/mL | … | … | … | 0.538 (P < .000) |
| Near delivery (n = 96) | ||||
| HBV DNA, log10 IU/mL | 0.300 (P = .003) | 0.182 (P = .076) | 0.374 (P < .000) | 0.263 (P = .010) |
| pgRNA, log10 copies/mL | … | 0.652 (P < .000) | 0.581 (P < .000) | 0.471 (P < .000) |
| HBcrAg, log10 U/mL | … | … | 0.475 (P < .000) | 0.660 (P < .000) |
| HBsAg, log10 IU/mL | … | … | … | 0.583 (P < .000) |
| Postpartum (n = 39) | ||||
| HBV DNA, log10 IU/mL | 0.332 (P = .039) | 0.173 (P = .291) | 0.332 (P = .039) | 0.332 (P = .039) |
| pgRNA, log10 copies/mL | … | 0.799 (P < .000) | 0.810 (P < .000) | 0.636 (P < .000) |
| HBcrAg, log10 U/mL | … | … | 0.627 (P < .000) | 0.739 (P < .000) |
| HBsAg, log10 IU/mL | … | … | … | 0.627 (P < .000) |
Correlation coefficients were calculated by Spearman's test; P = P value of correlation t test.
Abbreviations: HBcrAg, hepatitis B core-related antigen; HBeAg, hepatitis B e antigen; HBsAg, hepatitis B surface antigen; HBV, hepatitis B virus; pgRNA, pregenomic RNA.
Correlation Coefficients Between Different Viral Biomarkers in 96 Patients Receiving Antiviral Prophylaxis
| . | pgRNA, log10 copies/mL . | HBcrAg, log10 U/mL . | HBsAg, log10 IU/mL . | HBeAg, log10 PEIU/mL . |
|---|---|---|---|---|
| Baseline (n = 96) | ||||
| HBV DNA, log10 IU/mL | 0.353 (P < .000) | 0.324 (P = .001) | 0.314 (P = .002) | 0.207 (P = .043) |
| pgRNA, log10 copies/mL | … | 0.523 (P < .000) | 0.456 (P < .000) | 0.259 (P = .011) |
| HBcrAg, log10 U/mL | … | … | 0.490 (P < .000) | 0.513 (P < .000) |
| HBsAg, log10 IU/mL | … | … | … | 0.538 (P < .000) |
| Near delivery (n = 96) | ||||
| HBV DNA, log10 IU/mL | 0.300 (P = .003) | 0.182 (P = .076) | 0.374 (P < .000) | 0.263 (P = .010) |
| pgRNA, log10 copies/mL | … | 0.652 (P < .000) | 0.581 (P < .000) | 0.471 (P < .000) |
| HBcrAg, log10 U/mL | … | … | 0.475 (P < .000) | 0.660 (P < .000) |
| HBsAg, log10 IU/mL | … | … | … | 0.583 (P < .000) |
| Postpartum (n = 39) | ||||
| HBV DNA, log10 IU/mL | 0.332 (P = .039) | 0.173 (P = .291) | 0.332 (P = .039) | 0.332 (P = .039) |
| pgRNA, log10 copies/mL | … | 0.799 (P < .000) | 0.810 (P < .000) | 0.636 (P < .000) |
| HBcrAg, log10 U/mL | … | … | 0.627 (P < .000) | 0.739 (P < .000) |
| HBsAg, log10 IU/mL | … | … | … | 0.627 (P < .000) |
| . | pgRNA, log10 copies/mL . | HBcrAg, log10 U/mL . | HBsAg, log10 IU/mL . | HBeAg, log10 PEIU/mL . |
|---|---|---|---|---|
| Baseline (n = 96) | ||||
| HBV DNA, log10 IU/mL | 0.353 (P < .000) | 0.324 (P = .001) | 0.314 (P = .002) | 0.207 (P = .043) |
| pgRNA, log10 copies/mL | … | 0.523 (P < .000) | 0.456 (P < .000) | 0.259 (P = .011) |
| HBcrAg, log10 U/mL | … | … | 0.490 (P < .000) | 0.513 (P < .000) |
| HBsAg, log10 IU/mL | … | … | … | 0.538 (P < .000) |
| Near delivery (n = 96) | ||||
| HBV DNA, log10 IU/mL | 0.300 (P = .003) | 0.182 (P = .076) | 0.374 (P < .000) | 0.263 (P = .010) |
| pgRNA, log10 copies/mL | … | 0.652 (P < .000) | 0.581 (P < .000) | 0.471 (P < .000) |
| HBcrAg, log10 U/mL | … | … | 0.475 (P < .000) | 0.660 (P < .000) |
| HBsAg, log10 IU/mL | … | … | … | 0.583 (P < .000) |
| Postpartum (n = 39) | ||||
| HBV DNA, log10 IU/mL | 0.332 (P = .039) | 0.173 (P = .291) | 0.332 (P = .039) | 0.332 (P = .039) |
| pgRNA, log10 copies/mL | … | 0.799 (P < .000) | 0.810 (P < .000) | 0.636 (P < .000) |
| HBcrAg, log10 U/mL | … | … | 0.627 (P < .000) | 0.739 (P < .000) |
| HBsAg, log10 IU/mL | … | … | … | 0.627 (P < .000) |
Correlation coefficients were calculated by Spearman's test; P = P value of correlation t test.
Abbreviations: HBcrAg, hepatitis B core-related antigen; HBeAg, hepatitis B e antigen; HBsAg, hepatitis B surface antigen; HBV, hepatitis B virus; pgRNA, pregenomic RNA.
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