Table 1.

Patient Baseline Characteristics, Indications, and Infection Sites

CharacteristicTotal n = 98
Age, median (range), y62.5 (20–85)
Sex, No. (%)
 Male33 (33.7)
 Female65 (66.3)
Race, No. (%)
 White84 (85.7)
 Black or African American8 (8.2)
 Other or not reported6 (6.1)
Body mass index, median (range), kg/m226.33 (16.37–41.78)
Weight >90 kg, No. (%)28 (28.6)
Albumin, median (range), g/dL3.1 (1.7–4.8)
 Albumin ≤3 g/dL, No. (%)47 (48.0)
 Albumin >3 g/dL, No. (%)51 (52.0)
Malignancy, No. (%)
 Acute myeloid leukemia47 (48.0)
 Myelodysplastic syndrome15 (15.3)
 Lymphoma9 (9.2)
 Myeloproliferative neoplasms6 (6.1)
 Acute lymphocytic leukemia4 (4.1)
 Multiple myeloma1 (1.0)
 Other17 (17.3)
Stem cell transplant and cellular therapies
 Allogeneic49 (50.0)
 Chimeric antigen receptor–T therapy10 (10.2)
 Stem cell+ CAR-T therapy2 (2.0)
Acute gastrointestinal graft-vs-host disease, No. (%)10 (10.2)
Interacting drug—any, No. (%)82 (83.7)
 Proton pump inhibitor, No. (%)51 (52.0)
Diarrhea, No. (%)21 (21.4)
Indication for posaconazole, No. (%)
 Treatment76 (77.6)
 Prophylaxis22 (22.4)
Infections definition, No. (%)
 Possible44 (44.9)
 Probable24 (24.5)
 Proven5 (5.1)
 Not applicable (prophylaxis or undefined)25 (25.5)
Infection site, No. (%)
 Pulmonary62 (63.3)
 Rhino-cerebral7 (7.1)
 Cutaneous5 (5.1)
 Other2 (2.0)
 Not applicable (prophylaxis)22 (22.4)
Organism isolated, No. (%)28 (28.6)
CharacteristicTotal n = 98
Age, median (range), y62.5 (20–85)
Sex, No. (%)
 Male33 (33.7)
 Female65 (66.3)
Race, No. (%)
 White84 (85.7)
 Black or African American8 (8.2)
 Other or not reported6 (6.1)
Body mass index, median (range), kg/m226.33 (16.37–41.78)
Weight >90 kg, No. (%)28 (28.6)
Albumin, median (range), g/dL3.1 (1.7–4.8)
 Albumin ≤3 g/dL, No. (%)47 (48.0)
 Albumin >3 g/dL, No. (%)51 (52.0)
Malignancy, No. (%)
 Acute myeloid leukemia47 (48.0)
 Myelodysplastic syndrome15 (15.3)
 Lymphoma9 (9.2)
 Myeloproliferative neoplasms6 (6.1)
 Acute lymphocytic leukemia4 (4.1)
 Multiple myeloma1 (1.0)
 Other17 (17.3)
Stem cell transplant and cellular therapies
 Allogeneic49 (50.0)
 Chimeric antigen receptor–T therapy10 (10.2)
 Stem cell+ CAR-T therapy2 (2.0)
Acute gastrointestinal graft-vs-host disease, No. (%)10 (10.2)
Interacting drug—any, No. (%)82 (83.7)
 Proton pump inhibitor, No. (%)51 (52.0)
Diarrhea, No. (%)21 (21.4)
Indication for posaconazole, No. (%)
 Treatment76 (77.6)
 Prophylaxis22 (22.4)
Infections definition, No. (%)
 Possible44 (44.9)
 Probable24 (24.5)
 Proven5 (5.1)
 Not applicable (prophylaxis or undefined)25 (25.5)
Infection site, No. (%)
 Pulmonary62 (63.3)
 Rhino-cerebral7 (7.1)
 Cutaneous5 (5.1)
 Other2 (2.0)
 Not applicable (prophylaxis)22 (22.4)
Organism isolated, No. (%)28 (28.6)
Table 1.

Patient Baseline Characteristics, Indications, and Infection Sites

CharacteristicTotal n = 98
Age, median (range), y62.5 (20–85)
Sex, No. (%)
 Male33 (33.7)
 Female65 (66.3)
Race, No. (%)
 White84 (85.7)
 Black or African American8 (8.2)
 Other or not reported6 (6.1)
Body mass index, median (range), kg/m226.33 (16.37–41.78)
Weight >90 kg, No. (%)28 (28.6)
Albumin, median (range), g/dL3.1 (1.7–4.8)
 Albumin ≤3 g/dL, No. (%)47 (48.0)
 Albumin >3 g/dL, No. (%)51 (52.0)
Malignancy, No. (%)
 Acute myeloid leukemia47 (48.0)
 Myelodysplastic syndrome15 (15.3)
 Lymphoma9 (9.2)
 Myeloproliferative neoplasms6 (6.1)
 Acute lymphocytic leukemia4 (4.1)
 Multiple myeloma1 (1.0)
 Other17 (17.3)
Stem cell transplant and cellular therapies
 Allogeneic49 (50.0)
 Chimeric antigen receptor–T therapy10 (10.2)
 Stem cell+ CAR-T therapy2 (2.0)
Acute gastrointestinal graft-vs-host disease, No. (%)10 (10.2)
Interacting drug—any, No. (%)82 (83.7)
 Proton pump inhibitor, No. (%)51 (52.0)
Diarrhea, No. (%)21 (21.4)
Indication for posaconazole, No. (%)
 Treatment76 (77.6)
 Prophylaxis22 (22.4)
Infections definition, No. (%)
 Possible44 (44.9)
 Probable24 (24.5)
 Proven5 (5.1)
 Not applicable (prophylaxis or undefined)25 (25.5)
Infection site, No. (%)
 Pulmonary62 (63.3)
 Rhino-cerebral7 (7.1)
 Cutaneous5 (5.1)
 Other2 (2.0)
 Not applicable (prophylaxis)22 (22.4)
Organism isolated, No. (%)28 (28.6)
CharacteristicTotal n = 98
Age, median (range), y62.5 (20–85)
Sex, No. (%)
 Male33 (33.7)
 Female65 (66.3)
Race, No. (%)
 White84 (85.7)
 Black or African American8 (8.2)
 Other or not reported6 (6.1)
Body mass index, median (range), kg/m226.33 (16.37–41.78)
Weight >90 kg, No. (%)28 (28.6)
Albumin, median (range), g/dL3.1 (1.7–4.8)
 Albumin ≤3 g/dL, No. (%)47 (48.0)
 Albumin >3 g/dL, No. (%)51 (52.0)
Malignancy, No. (%)
 Acute myeloid leukemia47 (48.0)
 Myelodysplastic syndrome15 (15.3)
 Lymphoma9 (9.2)
 Myeloproliferative neoplasms6 (6.1)
 Acute lymphocytic leukemia4 (4.1)
 Multiple myeloma1 (1.0)
 Other17 (17.3)
Stem cell transplant and cellular therapies
 Allogeneic49 (50.0)
 Chimeric antigen receptor–T therapy10 (10.2)
 Stem cell+ CAR-T therapy2 (2.0)
Acute gastrointestinal graft-vs-host disease, No. (%)10 (10.2)
Interacting drug—any, No. (%)82 (83.7)
 Proton pump inhibitor, No. (%)51 (52.0)
Diarrhea, No. (%)21 (21.4)
Indication for posaconazole, No. (%)
 Treatment76 (77.6)
 Prophylaxis22 (22.4)
Infections definition, No. (%)
 Possible44 (44.9)
 Probable24 (24.5)
 Proven5 (5.1)
 Not applicable (prophylaxis or undefined)25 (25.5)
Infection site, No. (%)
 Pulmonary62 (63.3)
 Rhino-cerebral7 (7.1)
 Cutaneous5 (5.1)
 Other2 (2.0)
 Not applicable (prophylaxis)22 (22.4)
Organism isolated, No. (%)28 (28.6)
Close
This Feature Is Available To Subscribers Only

Sign In or Create an Account

Close

This PDF is available to Subscribers Only

View Article Abstract & Purchase Options

For full access to this pdf, sign in to an existing account, or purchase an annual subscription.

Close