Characteristic . | Total n = 98 . |
---|---|
Age, median (range), y | 62.5 (20–85) |
Sex, No. (%) | … |
Male | 33 (33.7) |
Female | 65 (66.3) |
Race, No. (%) | … |
White | 84 (85.7) |
Black or African American | 8 (8.2) |
Other or not reported | 6 (6.1) |
Body mass index, median (range), kg/m2 | 26.33 (16.37–41.78) |
Weight >90 kg, No. (%) | 28 (28.6) |
Albumin, median (range), g/dL | 3.1 (1.7–4.8) |
Albumin ≤3 g/dL, No. (%) | 47 (48.0) |
Albumin >3 g/dL, No. (%) | 51 (52.0) |
Malignancy, No. (%) | … |
Acute myeloid leukemia | 47 (48.0) |
Myelodysplastic syndrome | 15 (15.3) |
Lymphoma | 9 (9.2) |
Myeloproliferative neoplasms | 6 (6.1) |
Acute lymphocytic leukemia | 4 (4.1) |
Multiple myeloma | 1 (1.0) |
Other | 17 (17.3) |
Stem cell transplant and cellular therapies | … |
Allogeneic | 49 (50.0) |
Chimeric antigen receptor–T therapy | 10 (10.2) |
Stem cell+ CAR-T therapy | 2 (2.0) |
Acute gastrointestinal graft-vs-host disease, No. (%) | 10 (10.2) |
Interacting drug—any, No. (%) | 82 (83.7) |
Proton pump inhibitor, No. (%) | 51 (52.0) |
Diarrhea, No. (%) | 21 (21.4) |
Indication for posaconazole, No. (%) | … |
Treatment | 76 (77.6) |
Prophylaxis | 22 (22.4) |
Infections definition, No. (%) | … |
Possible | 44 (44.9) |
Probable | 24 (24.5) |
Proven | 5 (5.1) |
Not applicable (prophylaxis or undefined) | 25 (25.5) |
Infection site, No. (%) | … |
Pulmonary | 62 (63.3) |
Rhino-cerebral | 7 (7.1) |
Cutaneous | 5 (5.1) |
Other | 2 (2.0) |
Not applicable (prophylaxis) | 22 (22.4) |
Organism isolated, No. (%) | 28 (28.6) |
Characteristic . | Total n = 98 . |
---|---|
Age, median (range), y | 62.5 (20–85) |
Sex, No. (%) | … |
Male | 33 (33.7) |
Female | 65 (66.3) |
Race, No. (%) | … |
White | 84 (85.7) |
Black or African American | 8 (8.2) |
Other or not reported | 6 (6.1) |
Body mass index, median (range), kg/m2 | 26.33 (16.37–41.78) |
Weight >90 kg, No. (%) | 28 (28.6) |
Albumin, median (range), g/dL | 3.1 (1.7–4.8) |
Albumin ≤3 g/dL, No. (%) | 47 (48.0) |
Albumin >3 g/dL, No. (%) | 51 (52.0) |
Malignancy, No. (%) | … |
Acute myeloid leukemia | 47 (48.0) |
Myelodysplastic syndrome | 15 (15.3) |
Lymphoma | 9 (9.2) |
Myeloproliferative neoplasms | 6 (6.1) |
Acute lymphocytic leukemia | 4 (4.1) |
Multiple myeloma | 1 (1.0) |
Other | 17 (17.3) |
Stem cell transplant and cellular therapies | … |
Allogeneic | 49 (50.0) |
Chimeric antigen receptor–T therapy | 10 (10.2) |
Stem cell+ CAR-T therapy | 2 (2.0) |
Acute gastrointestinal graft-vs-host disease, No. (%) | 10 (10.2) |
Interacting drug—any, No. (%) | 82 (83.7) |
Proton pump inhibitor, No. (%) | 51 (52.0) |
Diarrhea, No. (%) | 21 (21.4) |
Indication for posaconazole, No. (%) | … |
Treatment | 76 (77.6) |
Prophylaxis | 22 (22.4) |
Infections definition, No. (%) | … |
Possible | 44 (44.9) |
Probable | 24 (24.5) |
Proven | 5 (5.1) |
Not applicable (prophylaxis or undefined) | 25 (25.5) |
Infection site, No. (%) | … |
Pulmonary | 62 (63.3) |
Rhino-cerebral | 7 (7.1) |
Cutaneous | 5 (5.1) |
Other | 2 (2.0) |
Not applicable (prophylaxis) | 22 (22.4) |
Organism isolated, No. (%) | 28 (28.6) |
Characteristic . | Total n = 98 . |
---|---|
Age, median (range), y | 62.5 (20–85) |
Sex, No. (%) | … |
Male | 33 (33.7) |
Female | 65 (66.3) |
Race, No. (%) | … |
White | 84 (85.7) |
Black or African American | 8 (8.2) |
Other or not reported | 6 (6.1) |
Body mass index, median (range), kg/m2 | 26.33 (16.37–41.78) |
Weight >90 kg, No. (%) | 28 (28.6) |
Albumin, median (range), g/dL | 3.1 (1.7–4.8) |
Albumin ≤3 g/dL, No. (%) | 47 (48.0) |
Albumin >3 g/dL, No. (%) | 51 (52.0) |
Malignancy, No. (%) | … |
Acute myeloid leukemia | 47 (48.0) |
Myelodysplastic syndrome | 15 (15.3) |
Lymphoma | 9 (9.2) |
Myeloproliferative neoplasms | 6 (6.1) |
Acute lymphocytic leukemia | 4 (4.1) |
Multiple myeloma | 1 (1.0) |
Other | 17 (17.3) |
Stem cell transplant and cellular therapies | … |
Allogeneic | 49 (50.0) |
Chimeric antigen receptor–T therapy | 10 (10.2) |
Stem cell+ CAR-T therapy | 2 (2.0) |
Acute gastrointestinal graft-vs-host disease, No. (%) | 10 (10.2) |
Interacting drug—any, No. (%) | 82 (83.7) |
Proton pump inhibitor, No. (%) | 51 (52.0) |
Diarrhea, No. (%) | 21 (21.4) |
Indication for posaconazole, No. (%) | … |
Treatment | 76 (77.6) |
Prophylaxis | 22 (22.4) |
Infections definition, No. (%) | … |
Possible | 44 (44.9) |
Probable | 24 (24.5) |
Proven | 5 (5.1) |
Not applicable (prophylaxis or undefined) | 25 (25.5) |
Infection site, No. (%) | … |
Pulmonary | 62 (63.3) |
Rhino-cerebral | 7 (7.1) |
Cutaneous | 5 (5.1) |
Other | 2 (2.0) |
Not applicable (prophylaxis) | 22 (22.4) |
Organism isolated, No. (%) | 28 (28.6) |
Characteristic . | Total n = 98 . |
---|---|
Age, median (range), y | 62.5 (20–85) |
Sex, No. (%) | … |
Male | 33 (33.7) |
Female | 65 (66.3) |
Race, No. (%) | … |
White | 84 (85.7) |
Black or African American | 8 (8.2) |
Other or not reported | 6 (6.1) |
Body mass index, median (range), kg/m2 | 26.33 (16.37–41.78) |
Weight >90 kg, No. (%) | 28 (28.6) |
Albumin, median (range), g/dL | 3.1 (1.7–4.8) |
Albumin ≤3 g/dL, No. (%) | 47 (48.0) |
Albumin >3 g/dL, No. (%) | 51 (52.0) |
Malignancy, No. (%) | … |
Acute myeloid leukemia | 47 (48.0) |
Myelodysplastic syndrome | 15 (15.3) |
Lymphoma | 9 (9.2) |
Myeloproliferative neoplasms | 6 (6.1) |
Acute lymphocytic leukemia | 4 (4.1) |
Multiple myeloma | 1 (1.0) |
Other | 17 (17.3) |
Stem cell transplant and cellular therapies | … |
Allogeneic | 49 (50.0) |
Chimeric antigen receptor–T therapy | 10 (10.2) |
Stem cell+ CAR-T therapy | 2 (2.0) |
Acute gastrointestinal graft-vs-host disease, No. (%) | 10 (10.2) |
Interacting drug—any, No. (%) | 82 (83.7) |
Proton pump inhibitor, No. (%) | 51 (52.0) |
Diarrhea, No. (%) | 21 (21.4) |
Indication for posaconazole, No. (%) | … |
Treatment | 76 (77.6) |
Prophylaxis | 22 (22.4) |
Infections definition, No. (%) | … |
Possible | 44 (44.9) |
Probable | 24 (24.5) |
Proven | 5 (5.1) |
Not applicable (prophylaxis or undefined) | 25 (25.5) |
Infection site, No. (%) | … |
Pulmonary | 62 (63.3) |
Rhino-cerebral | 7 (7.1) |
Cutaneous | 5 (5.1) |
Other | 2 (2.0) |
Not applicable (prophylaxis) | 22 (22.4) |
Organism isolated, No. (%) | 28 (28.6) |
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