Table 1: Open in new tab Clinical...

Parameters	All patients (n = 1170)	Females (n = 288)	Males (n = 882)	P-value
Preoperative features
Age (years), mean ± SD	66.7 ± 12	68 ± 14	66 ± 11	<.001
BMI (kg/m²), mean ± SD	27 ± 4.6	26 ± 6	27 ± 4	<.0001
Diabetes, n (%)	306 (26)	62 (22)	244 (28)	.04
Hypertension, n (%)	668 (57)	166 (58)	502 (58)	.83
PVD, n (%)	108 (9)	14 (5)	94 (11)	<.001
COPD, n (%)	126 (11)	35 (12)	91 (10)	.39
PAH, n (%)	157 (13.4	51 (18)	106 (12)	.02
EuroSCORE II, mean ± SD	2.6 ± 3.6	3.2 ± 3.4	2.4 ± 3.7	<.0001
LVEF (%), mean ± SD	56 ± 11	59 ± 9	55 ± 11	<.0001
Serum creatinine (μmol/l), mean ± SD	93 ± 36	80 ± 34	97 ± 35	<.0001
eGFR (ml/min.1.73 m²), mean ± SD	74 ± 21	72 ± 23	75 ± 20	.03
Kidney graft recipients, n (%)	13 (1)	5 (2)	8 (1)	.27
Perioperative features
Surgery, n (%)				<.0001
CAB	441 (38)	67 (23)	374 (42)
Valvular	374 (32)	137 (48)	237 (27)
Combined	176 (15)	30 (10)	146 (17)
Thoracic aorta	145 (12)	37 (13)	108 (12)
Myocardium	34 (3)	17 (6)	17 (2)
Previous cardiac surgery, n (%)	80 (7)	30 (10)	50 (6)	<.01
CBP time (min), mean ± SD	87 ± 36	81 ± 40	89 ± 35	<.0001
RBC transfusion, n (%)	150 (13)	74 (26)	76 (9)	<.0001
Mean ± SD	0.3 ± 0.9	0.6 ± 1.2	0.2 ± 0.7	<.0001
Vasoactive agents, n (%)	1083 (93)	272 (94)	811 (92)	.15
Postoperative features
SAPS II score, mean ± SD	33 ± 12	34 ± 12	32 ± 11	<.01
RBC transfusion, n (%)	306 (26)	100 (35)	206 (23)	<.001
Mean ± SD	0.7 ± 1.8	0.9 ± 2.1	0.7 ± 1.7	.001
Vasoactive agents, n (%)	727 (62)	181 (63)	541 (61)	.65
CVP (mmHg), mean ± SD	12.3 ± 5.5	12.3 ± 7.4	12.3 ± 4.8	.48
Infection, n (%)	195 (17)	34 (12)	161 (18)	<.01
Iodinated contrast agents, n (%)	32 (3)	8 (3)	24 (3)	.96
Fluid infusion day 1
ml, mean ± SD	1182 ± 716	1205 ± 713	1174 ± 718	.53
ml/kg, mean ± SD	16 ± 11	19 ± 13	15 ± 10	<.0001
ICU stay (days), mean ± SD	4.8 ± 6	4.7 ± 4.7	4.8 ± 6.3	.29
Outcomes
AKI KDIGO stage, n (%)				.99
0	875 (74)	214 (74)	661 (75)
1	160 (14)	39 (14)	121 (14)
2	92 (8)	24 (8)	68 (8)
3	43 (4)	11 (4)	32 (4)
RRT, n (%)	32 (3)	10 (3)	22 (2)	.52
In-hospital mortality, n (%)	38 (3)	13 (4.5)	25 (2.8)	.18

Parameters

All patients (n = 1170)

Females (n = 288)

Males (n = 882)

P-value

Preoperative features

Age (years), mean ± SD

66.7 ± 12

68 ± 14

66 ± 11

<.001

BMI (kg/m²), mean ± SD

27 ± 4.6

26 ± 6

27 ± 4

<.0001

Diabetes, n (%)

306 (26)

62 (22)

244 (28)

.04

Hypertension, n (%)

668 (57)

166 (58)

502 (58)

.83

PVD, n (%)

108 (9)

14 (5)

94 (11)

<.001

COPD, n (%)

126 (11)

35 (12)

91 (10)

.39

PAH, n (%)

157 (13.4

51 (18)

106 (12)

.02

EuroSCORE II, mean ± SD

2.6 ± 3.6

3.2 ± 3.4

2.4 ± 3.7

<.0001

LVEF (%), mean ± SD

56 ± 11

59 ± 9

55 ± 11

<.0001

Serum creatinine (μmol/l), mean ± SD

93 ± 36

80 ± 34

97 ± 35

<.0001

eGFR (ml/min.1.73 m²), mean ± SD

74 ± 21

72 ± 23

75 ± 20

.03

Kidney graft recipients, n (%)

13 (1)

5 (2)

8 (1)

.27

Perioperative features

Surgery, n (%)

<.0001

CAB

441 (38)

67 (23)

374 (42)

Valvular

374 (32)

137 (48)

237 (27)

Combined

176 (15)

30 (10)

146 (17)

Thoracic aorta

145 (12)

37 (13)

108 (12)

Myocardium

34 (3)

17 (6)

17 (2)

Previous cardiac surgery, n (%)

80 (7)

30 (10)

50 (6)

<.01

CBP time (min), mean ± SD

87 ± 36

81 ± 40

89 ± 35

<.0001

RBC transfusion, n (%)

150 (13)

74 (26)

76 (9)

<.0001

Mean ± SD

0.3 ± 0.9

0.6 ± 1.2

0.2 ± 0.7

<.0001

Vasoactive agents, n (%)

1083 (93)

272 (94)

811 (92)

.15

Postoperative features

SAPS II score, mean ± SD

33 ± 12

34 ± 12

32 ± 11

<.01

RBC transfusion, n (%)

306 (26)

100 (35)

206 (23)

<.001

Mean ± SD

0.7 ± 1.8

0.9 ± 2.1

0.7 ± 1.7

.001

Vasoactive agents, n (%)

727 (62)

181 (63)

541 (61)

.65

CVP (mmHg), mean ± SD

12.3 ± 5.5

12.3 ± 7.4

12.3 ± 4.8

.48

Infection, n (%)

195 (17)

34 (12)

161 (18)

<.01

Iodinated contrast agents, n (%)

32 (3)

8 (3)

24 (3)

.96

Fluid infusion day 1

ml, mean ± SD

1182 ± 716

1205 ± 713

1174 ± 718

.53

ml/kg, mean ± SD

16 ± 11

19 ± 13

15 ± 10

<.0001

ICU stay (days), mean ± SD

4.8 ± 6

4.7 ± 4.7

4.8 ± 6.3

.29

Outcomes

AKI KDIGO stage, n (%)

.99

875 (74)

214 (74)

661 (75)

160 (14)

39 (14)

121 (14)

92 (8)

24 (8)

68 (8)

43 (4)

11 (4)

32 (4)

RRT, n (%)

32 (3)

10 (3)

22 (2)

.52

In-hospital mortality, n (%)

38 (3)

13 (4.5)

25 (2.8)

.18

Parameters	All patients (n = 1170)	Females (n = 288)	Males (n = 882)	P-value
Preoperative features
Age (years), mean ± SD	66.7 ± 12	68 ± 14	66 ± 11	<.001
BMI (kg/m²), mean ± SD	27 ± 4.6	26 ± 6	27 ± 4	<.0001
Diabetes, n (%)	306 (26)	62 (22)	244 (28)	.04
Hypertension, n (%)	668 (57)	166 (58)	502 (58)	.83
PVD, n (%)	108 (9)	14 (5)	94 (11)	<.001
COPD, n (%)	126 (11)	35 (12)	91 (10)	.39
PAH, n (%)	157 (13.4	51 (18)	106 (12)	.02
EuroSCORE II, mean ± SD	2.6 ± 3.6	3.2 ± 3.4	2.4 ± 3.7	<.0001
LVEF (%), mean ± SD	56 ± 11	59 ± 9	55 ± 11	<.0001
Serum creatinine (μmol/l), mean ± SD	93 ± 36	80 ± 34	97 ± 35	<.0001
eGFR (ml/min.1.73 m²), mean ± SD	74 ± 21	72 ± 23	75 ± 20	.03
Kidney graft recipients, n (%)	13 (1)	5 (2)	8 (1)	.27
Perioperative features
Surgery, n (%)				<.0001
CAB	441 (38)	67 (23)	374 (42)
Valvular	374 (32)	137 (48)	237 (27)
Combined	176 (15)	30 (10)	146 (17)
Thoracic aorta	145 (12)	37 (13)	108 (12)
Myocardium	34 (3)	17 (6)	17 (2)
Previous cardiac surgery, n (%)	80 (7)	30 (10)	50 (6)	<.01
CBP time (min), mean ± SD	87 ± 36	81 ± 40	89 ± 35	<.0001
RBC transfusion, n (%)	150 (13)	74 (26)	76 (9)	<.0001
Mean ± SD	0.3 ± 0.9	0.6 ± 1.2	0.2 ± 0.7	<.0001
Vasoactive agents, n (%)	1083 (93)	272 (94)	811 (92)	.15
Postoperative features
SAPS II score, mean ± SD	33 ± 12	34 ± 12	32 ± 11	<.01
RBC transfusion, n (%)	306 (26)	100 (35)	206 (23)	<.001
Mean ± SD	0.7 ± 1.8	0.9 ± 2.1	0.7 ± 1.7	.001
Vasoactive agents, n (%)	727 (62)	181 (63)	541 (61)	.65
CVP (mmHg), mean ± SD	12.3 ± 5.5	12.3 ± 7.4	12.3 ± 4.8	.48
Infection, n (%)	195 (17)	34 (12)	161 (18)	<.01
Iodinated contrast agents, n (%)	32 (3)	8 (3)	24 (3)	.96
Fluid infusion day 1
ml, mean ± SD	1182 ± 716	1205 ± 713	1174 ± 718	.53
ml/kg, mean ± SD	16 ± 11	19 ± 13	15 ± 10	<.0001
ICU stay (days), mean ± SD	4.8 ± 6	4.7 ± 4.7	4.8 ± 6.3	.29
Outcomes
AKI KDIGO stage, n (%)				.99
0	875 (74)	214 (74)	661 (75)
1	160 (14)	39 (14)	121 (14)
2	92 (8)	24 (8)	68 (8)
3	43 (4)	11 (4)	32 (4)
RRT, n (%)	32 (3)	10 (3)	22 (2)	.52
In-hospital mortality, n (%)	38 (3)	13 (4.5)	25 (2.8)	.18

Table 1:

Open in new tab

Clinical characteristics according to sex.

Parameters	All patients (n = 1170)	Females (n = 288)	Males (n = 882)	P-value
Preoperative features
Age (years), mean ± SD	66.7 ± 12	68 ± 14	66 ± 11	<.001
BMI (kg/m²), mean ± SD	27 ± 4.6	26 ± 6	27 ± 4	<.0001
Diabetes, n (%)	306 (26)	62 (22)	244 (28)	.04
Hypertension, n (%)	668 (57)	166 (58)	502 (58)	.83
PVD, n (%)	108 (9)	14 (5)	94 (11)	<.001
COPD, n (%)	126 (11)	35 (12)	91 (10)	.39
PAH, n (%)	157 (13.4	51 (18)	106 (12)	.02
EuroSCORE II, mean ± SD	2.6 ± 3.6	3.2 ± 3.4	2.4 ± 3.7	<.0001
LVEF (%), mean ± SD	56 ± 11	59 ± 9	55 ± 11	<.0001
Serum creatinine (μmol/l), mean ± SD	93 ± 36	80 ± 34	97 ± 35	<.0001
eGFR (ml/min.1.73 m²), mean ± SD	74 ± 21	72 ± 23	75 ± 20	.03
Kidney graft recipients, n (%)	13 (1)	5 (2)	8 (1)	.27
Perioperative features
Surgery, n (%)				<.0001
CAB	441 (38)	67 (23)	374 (42)
Valvular	374 (32)	137 (48)	237 (27)
Combined	176 (15)	30 (10)	146 (17)
Thoracic aorta	145 (12)	37 (13)	108 (12)
Myocardium	34 (3)	17 (6)	17 (2)
Previous cardiac surgery, n (%)	80 (7)	30 (10)	50 (6)	<.01
CBP time (min), mean ± SD	87 ± 36	81 ± 40	89 ± 35	<.0001
RBC transfusion, n (%)	150 (13)	74 (26)	76 (9)	<.0001
Mean ± SD	0.3 ± 0.9	0.6 ± 1.2	0.2 ± 0.7	<.0001
Vasoactive agents, n (%)	1083 (93)	272 (94)	811 (92)	.15
Postoperative features
SAPS II score, mean ± SD	33 ± 12	34 ± 12	32 ± 11	<.01
RBC transfusion, n (%)	306 (26)	100 (35)	206 (23)	<.001
Mean ± SD	0.7 ± 1.8	0.9 ± 2.1	0.7 ± 1.7	.001
Vasoactive agents, n (%)	727 (62)	181 (63)	541 (61)	.65
CVP (mmHg), mean ± SD	12.3 ± 5.5	12.3 ± 7.4	12.3 ± 4.8	.48
Infection, n (%)	195 (17)	34 (12)	161 (18)	<.01
Iodinated contrast agents, n (%)	32 (3)	8 (3)	24 (3)	.96
Fluid infusion day 1
ml, mean ± SD	1182 ± 716	1205 ± 713	1174 ± 718	.53
ml/kg, mean ± SD	16 ± 11	19 ± 13	15 ± 10	<.0001
ICU stay (days), mean ± SD	4.8 ± 6	4.7 ± 4.7	4.8 ± 6.3	.29
Outcomes
AKI KDIGO stage, n (%)				.99
0	875 (74)	214 (74)	661 (75)
1	160 (14)	39 (14)	121 (14)
2	92 (8)	24 (8)	68 (8)
3	43 (4)	11 (4)	32 (4)
RRT, n (%)	32 (3)	10 (3)	22 (2)	.52
In-hospital mortality, n (%)	38 (3)	13 (4.5)	25 (2.8)	.18

Parameters	All patients (n = 1170)	Females (n = 288)	Males (n = 882)	P-value
Preoperative features
Age (years), mean ± SD	66.7 ± 12	68 ± 14	66 ± 11	<.001
BMI (kg/m²), mean ± SD	27 ± 4.6	26 ± 6	27 ± 4	<.0001
Diabetes, n (%)	306 (26)	62 (22)	244 (28)	.04
Hypertension, n (%)	668 (57)	166 (58)	502 (58)	.83
PVD, n (%)	108 (9)	14 (5)	94 (11)	<.001
COPD, n (%)	126 (11)	35 (12)	91 (10)	.39
PAH, n (%)	157 (13.4	51 (18)	106 (12)	.02
EuroSCORE II, mean ± SD	2.6 ± 3.6	3.2 ± 3.4	2.4 ± 3.7	<.0001
LVEF (%), mean ± SD	56 ± 11	59 ± 9	55 ± 11	<.0001
Serum creatinine (μmol/l), mean ± SD	93 ± 36	80 ± 34	97 ± 35	<.0001
eGFR (ml/min.1.73 m²), mean ± SD	74 ± 21	72 ± 23	75 ± 20	.03
Kidney graft recipients, n (%)	13 (1)	5 (2)	8 (1)	.27
Perioperative features
Surgery, n (%)				<.0001
CAB	441 (38)	67 (23)	374 (42)
Valvular	374 (32)	137 (48)	237 (27)
Combined	176 (15)	30 (10)	146 (17)
Thoracic aorta	145 (12)	37 (13)	108 (12)
Myocardium	34 (3)	17 (6)	17 (2)
Previous cardiac surgery, n (%)	80 (7)	30 (10)	50 (6)	<.01
CBP time (min), mean ± SD	87 ± 36	81 ± 40	89 ± 35	<.0001
RBC transfusion, n (%)	150 (13)	74 (26)	76 (9)	<.0001
Mean ± SD	0.3 ± 0.9	0.6 ± 1.2	0.2 ± 0.7	<.0001
Vasoactive agents, n (%)	1083 (93)	272 (94)	811 (92)	.15
Postoperative features
SAPS II score, mean ± SD	33 ± 12	34 ± 12	32 ± 11	<.01
RBC transfusion, n (%)	306 (26)	100 (35)	206 (23)	<.001
Mean ± SD	0.7 ± 1.8	0.9 ± 2.1	0.7 ± 1.7	.001
Vasoactive agents, n (%)	727 (62)	181 (63)	541 (61)	.65
CVP (mmHg), mean ± SD	12.3 ± 5.5	12.3 ± 7.4	12.3 ± 4.8	.48
Infection, n (%)	195 (17)	34 (12)	161 (18)	<.01
Iodinated contrast agents, n (%)	32 (3)	8 (3)	24 (3)	.96
Fluid infusion day 1
ml, mean ± SD	1182 ± 716	1205 ± 713	1174 ± 718	.53
ml/kg, mean ± SD	16 ± 11	19 ± 13	15 ± 10	<.0001
ICU stay (days), mean ± SD	4.8 ± 6	4.7 ± 4.7	4.8 ± 6.3	.29
Outcomes
AKI KDIGO stage, n (%)				.99
0	875 (74)	214 (74)	661 (75)
1	160 (14)	39 (14)	121 (14)
2	92 (8)	24 (8)	68 (8)
3	43 (4)	11 (4)	32 (4)
RRT, n (%)	32 (3)	10 (3)	22 (2)	.52
In-hospital mortality, n (%)	38 (3)	13 (4.5)	25 (2.8)	.18

COPD: chronic obstructive pulmonary disease; CVP, central venous pressure; PVD: peripheral vascular disease; PAH: pulmonary arterial hypertension.

This Feature Is Available To Subscribers Only