Adjusted relationships between baseline RVol, LAV, and RVol/LAV ratio and HF hospitalization according to treatment
| . | GDMT alone . | TEER plus GDMT . | ||||
|---|---|---|---|---|---|---|
| . | Adjusted HRa [95% CI] . | P-value . | AIC . | Adjusted HR* [95% CI] . | P-value . | AIC . |
| Model 1: RVol/LAV ratio | 1.77 [1.20, 2.63] | 0.004 | 1147 | 0.68 [0.39, 1.18] | 0.17 | 606 |
| Model 2: RVol, per 10 mL | 1.03 [0.93, 1.14] | 0.59 | 1153 | 0.99 [0.86, 1.14] | 0.87 | 608 |
| Model 3: LAV, per 10 mL | 1.05 [1.00, 1.09] | 0.06 | 1150 | 0.97 [0.90, 1.04] | 0.42 | 607 |
| . | GDMT alone . | TEER plus GDMT . | ||||
|---|---|---|---|---|---|---|
| . | Adjusted HRa [95% CI] . | P-value . | AIC . | Adjusted HR* [95% CI] . | P-value . | AIC . |
| Model 1: RVol/LAV ratio | 1.77 [1.20, 2.63] | 0.004 | 1147 | 0.68 [0.39, 1.18] | 0.17 | 606 |
| Model 2: RVol, per 10 mL | 1.03 [0.93, 1.14] | 0.59 | 1153 | 0.99 [0.86, 1.14] | 0.87 | 608 |
| Model 3: LAV, per 10 mL | 1.05 [1.00, 1.09] | 0.06 | 1150 | 0.97 [0.90, 1.04] | 0.42 | 607 |
AIC, Akaike Information Criterion; CI, confidence interval; GDMT, guideline-directed medical therapy; HF, heart failure; HR, hazard ratio; LAV, left atrial volume; RVol, regurgitant volume; TEER, transcatheter edge-to-edge therapy.
aAdjusted for age, sex, diabetes, hypertension, history of atrial fibrillation/flutter, estimated glomerular filtration rate, left ventricular ejection fraction, left ventricular global longitudinal strain, left ventricular end-diastolic volume, and right ventricular systolic pressure.
Adjusted relationships between baseline RVol, LAV, and RVol/LAV ratio and HF hospitalization according to treatment
| . | GDMT alone . | TEER plus GDMT . | ||||
|---|---|---|---|---|---|---|
| . | Adjusted HRa [95% CI] . | P-value . | AIC . | Adjusted HR* [95% CI] . | P-value . | AIC . |
| Model 1: RVol/LAV ratio | 1.77 [1.20, 2.63] | 0.004 | 1147 | 0.68 [0.39, 1.18] | 0.17 | 606 |
| Model 2: RVol, per 10 mL | 1.03 [0.93, 1.14] | 0.59 | 1153 | 0.99 [0.86, 1.14] | 0.87 | 608 |
| Model 3: LAV, per 10 mL | 1.05 [1.00, 1.09] | 0.06 | 1150 | 0.97 [0.90, 1.04] | 0.42 | 607 |
| . | GDMT alone . | TEER plus GDMT . | ||||
|---|---|---|---|---|---|---|
| . | Adjusted HRa [95% CI] . | P-value . | AIC . | Adjusted HR* [95% CI] . | P-value . | AIC . |
| Model 1: RVol/LAV ratio | 1.77 [1.20, 2.63] | 0.004 | 1147 | 0.68 [0.39, 1.18] | 0.17 | 606 |
| Model 2: RVol, per 10 mL | 1.03 [0.93, 1.14] | 0.59 | 1153 | 0.99 [0.86, 1.14] | 0.87 | 608 |
| Model 3: LAV, per 10 mL | 1.05 [1.00, 1.09] | 0.06 | 1150 | 0.97 [0.90, 1.04] | 0.42 | 607 |
AIC, Akaike Information Criterion; CI, confidence interval; GDMT, guideline-directed medical therapy; HF, heart failure; HR, hazard ratio; LAV, left atrial volume; RVol, regurgitant volume; TEER, transcatheter edge-to-edge therapy.
aAdjusted for age, sex, diabetes, hypertension, history of atrial fibrillation/flutter, estimated glomerular filtration rate, left ventricular ejection fraction, left ventricular global longitudinal strain, left ventricular end-diastolic volume, and right ventricular systolic pressure.
This PDF is available to Subscribers Only
View Article Abstract & Purchase OptionsFor full access to this pdf, sign in to an existing account, or purchase an annual subscription.
