Table 4 Open in new tab Univariable and...

Variable	Univariable models	Multivariable models
Prediction of RV ejection fraction
RV amyloid	−3.61	−5.27 to −1.95	<0.001	−4.15	−7.44 to −0.87	0.014
LV amyloid	−1.81	−2.87 to −0.75	0.001	0.44	−1.59–2.48	0.667
Lung amyloid	−0.59	−1.44–0.26	0.171	−0.12	−0.96–0.71	0.771
Prediction of RV free wall longitudinal strain
RV amyloid	2.84	2.07–3.62	<0.001	3.13	1.59–4.66	<0.001
LV amyloid	1.45	0.93–1.97	<0.001	−0.29	−1.24–0.66	0.551
Lung amyloid	0.49	0.08–0.89	0.018	0.19	−0.15–0.54	0.268

Variable	Univariable models	Multivariable models
Prediction of RV ejection fraction
RV amyloid	−3.61	−5.27 to −1.95	<0.001	−4.15	−7.44 to −0.87	0.014
LV amyloid	−1.81	−2.87 to −0.75	0.001	0.44	−1.59–2.48	0.667
Lung amyloid	−0.59	−1.44–0.26	0.171	−0.12	−0.96–0.71	0.771
Prediction of RV free wall longitudinal strain
RV amyloid	2.84	2.07–3.62	<0.001	3.13	1.59–4.66	<0.001
LV amyloid	1.45	0.93–1.97	<0.001	−0.29	−1.24–0.66	0.551
Lung amyloid	0.49	0.08–0.89	0.018	0.19	−0.15–0.54	0.268

Table 4

Univariable and multivariable-adjusted predictors of RV function

Variable	Univariable models			Multivariable models
	Coefficient	95% confidence interval	P-value	Coefficient	95% confidence interval	P-value
Prediction of RV ejection fraction
RV amyloid	−3.61	−5.27 to −1.95	<0.001	−4.15	−7.44 to −0.87	0.014
LV amyloid	−1.81	−2.87 to −0.75	0.001	0.44	−1.59–2.48	0.667
Lung amyloid	−0.59	−1.44–0.26	0.171	−0.12	−0.96–0.71	0.771
Prediction of RV free wall longitudinal strain
RV amyloid	2.84	2.07–3.62	<0.001	3.13	1.59–4.66	<0.001
LV amyloid	1.45	0.93–1.97	<0.001	−0.29	−1.24–0.66	0.551
Lung amyloid	0.49	0.08–0.89	0.018	0.19	−0.15–0.54	0.268

Variable	Univariable models			Multivariable models
	Coefficient	95% confidence interval	P-value	Coefficient	95% confidence interval	P-value
Prediction of RV ejection fraction
RV amyloid	−3.61	−5.27 to −1.95	<0.001	−4.15	−7.44 to −0.87	0.014
LV amyloid	−1.81	−2.87 to −0.75	0.001	0.44	−1.59–2.48	0.667
Lung amyloid	−0.59	−1.44–0.26	0.171	−0.12	−0.96–0.71	0.771
Prediction of RV free wall longitudinal strain
RV amyloid	2.84	2.07–3.62	<0.001	3.13	1.59–4.66	<0.001
LV amyloid	1.45	0.93–1.97	<0.001	−0.29	−1.24–0.66	0.551
Lung amyloid	0.49	0.08–0.89	0.018	0.19	−0.15–0.54	0.268

RV, LV, and lung amyloid burden were measured on ¹⁸F-florbetapir PET/CT, RV ejection fraction on MRI, and RV free wall longitudinal strain on echocardiography. Models were fit using linear regression. Each multivariable model included RV, LV, and lung amyloid.

LV, left ventricular; RV, right ventricular.

This Feature Is Available To Subscribers Only