Table 1

Baseline clinical and laboratory data characteristics

CharacteristicsAllSRAFP-values (AF vs. SR)
n = 23n = 16n = 7
Age (years)76 ± 576 ± 576 ± 60.8667
Male, n (%)23 (100)16 (100)7 (100)1.0000
Hypertension, n (%)17 (74)12 (75)5 (71)1.0000
Diabetes Mellitus, n (%)8 (34)4 (25)4 (57)0.1819
Dyslipidaemia, n (%)6 (26)5 (31)1 (14)0.6214
Obesity, n (%)4 (17)4 (25)0 (0)0.2727
BMI (kg/m2)22.6 ± 2.522.8 ± 622.2 ± 1.60.5034
NYHA class II, n (%)15 (65)12 (75)3 (43)0.1819
NYHA class III, n (%)8 (35)4 (25)4 (57)0.1819
SBP (mmHg)118 ± 20124 ± 20106 ± 140.0817
DBP (mmHg)73 ± 1476 ± 1467 ± 110.1238
Heart rate (/min)69 ± 967 ± 974 ± 80.0944
Hb (g/dL)13.8 ± 1.214.3 ± 1.313.8 ± 1.20.4824
eGFR (mL/min/1.73m2)46 ± 1448 ± 1143 ± 190.1923
AST (IU/L)24 (19–27)24 (19–27)23 (17–31)0.9466
ALT (IU/L)17 (10–19)17 (11–20)12 (9–18)0.2538
CK (IU/L)94 (68–160)98 (70–167)71 (40–156)0.2421
Hs-TnT (ng/mL)0.064 (0.042–0.099)0.062 (0.039–0.094)0.066 (0.053–0.105)0.4828
LDL-C (mg/dL)92 ± 3190 ± 3099 ± 330.5697
NT-proBNP (pg/mL)1898 (832–3291)1697 (762–1981)3533 (2284–7168)0.0177
ACEi/ARB, n (%)11 (58)7 (48)4 (57)0.6668
Beta blocker, n (%)15 (65)8 (50)7 (100)0.0520
MRA, n (%)8 (34)6 (38)2 (29)1.0000
Diuretics, n (%)11 (48)6 (38)5 (71)0.1930
ARNI, n (%)2 (9)2 (13)0 (0)1.0000
SGLT2I, n (%)5 (22)4 (25)1 (14)1.0000
CCB, n (%)3 (13)0 (0)3 (19)0.5257
CharacteristicsAllSRAFP-values (AF vs. SR)
n = 23n = 16n = 7
Age (years)76 ± 576 ± 576 ± 60.8667
Male, n (%)23 (100)16 (100)7 (100)1.0000
Hypertension, n (%)17 (74)12 (75)5 (71)1.0000
Diabetes Mellitus, n (%)8 (34)4 (25)4 (57)0.1819
Dyslipidaemia, n (%)6 (26)5 (31)1 (14)0.6214
Obesity, n (%)4 (17)4 (25)0 (0)0.2727
BMI (kg/m2)22.6 ± 2.522.8 ± 622.2 ± 1.60.5034
NYHA class II, n (%)15 (65)12 (75)3 (43)0.1819
NYHA class III, n (%)8 (35)4 (25)4 (57)0.1819
SBP (mmHg)118 ± 20124 ± 20106 ± 140.0817
DBP (mmHg)73 ± 1476 ± 1467 ± 110.1238
Heart rate (/min)69 ± 967 ± 974 ± 80.0944
Hb (g/dL)13.8 ± 1.214.3 ± 1.313.8 ± 1.20.4824
eGFR (mL/min/1.73m2)46 ± 1448 ± 1143 ± 190.1923
AST (IU/L)24 (19–27)24 (19–27)23 (17–31)0.9466
ALT (IU/L)17 (10–19)17 (11–20)12 (9–18)0.2538
CK (IU/L)94 (68–160)98 (70–167)71 (40–156)0.2421
Hs-TnT (ng/mL)0.064 (0.042–0.099)0.062 (0.039–0.094)0.066 (0.053–0.105)0.4828
LDL-C (mg/dL)92 ± 3190 ± 3099 ± 330.5697
NT-proBNP (pg/mL)1898 (832–3291)1697 (762–1981)3533 (2284–7168)0.0177
ACEi/ARB, n (%)11 (58)7 (48)4 (57)0.6668
Beta blocker, n (%)15 (65)8 (50)7 (100)0.0520
MRA, n (%)8 (34)6 (38)2 (29)1.0000
Diuretics, n (%)11 (48)6 (38)5 (71)0.1930
ARNI, n (%)2 (9)2 (13)0 (0)1.0000
SGLT2I, n (%)5 (22)4 (25)1 (14)1.0000
CCB, n (%)3 (13)0 (0)3 (19)0.5257

ACEI, angiotensin-converting enzyme inhibitor; ALT, alanine aminotransferase; ARB, angiotensin II receptor blocker; ARNI, angiotensin receptor neprilysin inhibitor; AST, aspartate aminotransferase; BMI, body mass index; CCB, calcium channel blocker; CK, creatine kinase; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; Hb, haemoglobin; Hs-TnT, high-sensitivity troponin T; LDL-C, low-density lipoprotein cholesterol; MRA, mineralocorticoid receptor antagonist; NT-proBNP, N-terminal pro–B-type natriuretic peptide; NYHA, New York Heart Association; SBP, systolic blood pressure; SGLT2, sodium-glucose co-transporter 2.

Table 1

Baseline clinical and laboratory data characteristics

CharacteristicsAllSRAFP-values (AF vs. SR)
n = 23n = 16n = 7
Age (years)76 ± 576 ± 576 ± 60.8667
Male, n (%)23 (100)16 (100)7 (100)1.0000
Hypertension, n (%)17 (74)12 (75)5 (71)1.0000
Diabetes Mellitus, n (%)8 (34)4 (25)4 (57)0.1819
Dyslipidaemia, n (%)6 (26)5 (31)1 (14)0.6214
Obesity, n (%)4 (17)4 (25)0 (0)0.2727
BMI (kg/m2)22.6 ± 2.522.8 ± 622.2 ± 1.60.5034
NYHA class II, n (%)15 (65)12 (75)3 (43)0.1819
NYHA class III, n (%)8 (35)4 (25)4 (57)0.1819
SBP (mmHg)118 ± 20124 ± 20106 ± 140.0817
DBP (mmHg)73 ± 1476 ± 1467 ± 110.1238
Heart rate (/min)69 ± 967 ± 974 ± 80.0944
Hb (g/dL)13.8 ± 1.214.3 ± 1.313.8 ± 1.20.4824
eGFR (mL/min/1.73m2)46 ± 1448 ± 1143 ± 190.1923
AST (IU/L)24 (19–27)24 (19–27)23 (17–31)0.9466
ALT (IU/L)17 (10–19)17 (11–20)12 (9–18)0.2538
CK (IU/L)94 (68–160)98 (70–167)71 (40–156)0.2421
Hs-TnT (ng/mL)0.064 (0.042–0.099)0.062 (0.039–0.094)0.066 (0.053–0.105)0.4828
LDL-C (mg/dL)92 ± 3190 ± 3099 ± 330.5697
NT-proBNP (pg/mL)1898 (832–3291)1697 (762–1981)3533 (2284–7168)0.0177
ACEi/ARB, n (%)11 (58)7 (48)4 (57)0.6668
Beta blocker, n (%)15 (65)8 (50)7 (100)0.0520
MRA, n (%)8 (34)6 (38)2 (29)1.0000
Diuretics, n (%)11 (48)6 (38)5 (71)0.1930
ARNI, n (%)2 (9)2 (13)0 (0)1.0000
SGLT2I, n (%)5 (22)4 (25)1 (14)1.0000
CCB, n (%)3 (13)0 (0)3 (19)0.5257
CharacteristicsAllSRAFP-values (AF vs. SR)
n = 23n = 16n = 7
Age (years)76 ± 576 ± 576 ± 60.8667
Male, n (%)23 (100)16 (100)7 (100)1.0000
Hypertension, n (%)17 (74)12 (75)5 (71)1.0000
Diabetes Mellitus, n (%)8 (34)4 (25)4 (57)0.1819
Dyslipidaemia, n (%)6 (26)5 (31)1 (14)0.6214
Obesity, n (%)4 (17)4 (25)0 (0)0.2727
BMI (kg/m2)22.6 ± 2.522.8 ± 622.2 ± 1.60.5034
NYHA class II, n (%)15 (65)12 (75)3 (43)0.1819
NYHA class III, n (%)8 (35)4 (25)4 (57)0.1819
SBP (mmHg)118 ± 20124 ± 20106 ± 140.0817
DBP (mmHg)73 ± 1476 ± 1467 ± 110.1238
Heart rate (/min)69 ± 967 ± 974 ± 80.0944
Hb (g/dL)13.8 ± 1.214.3 ± 1.313.8 ± 1.20.4824
eGFR (mL/min/1.73m2)46 ± 1448 ± 1143 ± 190.1923
AST (IU/L)24 (19–27)24 (19–27)23 (17–31)0.9466
ALT (IU/L)17 (10–19)17 (11–20)12 (9–18)0.2538
CK (IU/L)94 (68–160)98 (70–167)71 (40–156)0.2421
Hs-TnT (ng/mL)0.064 (0.042–0.099)0.062 (0.039–0.094)0.066 (0.053–0.105)0.4828
LDL-C (mg/dL)92 ± 3190 ± 3099 ± 330.5697
NT-proBNP (pg/mL)1898 (832–3291)1697 (762–1981)3533 (2284–7168)0.0177
ACEi/ARB, n (%)11 (58)7 (48)4 (57)0.6668
Beta blocker, n (%)15 (65)8 (50)7 (100)0.0520
MRA, n (%)8 (34)6 (38)2 (29)1.0000
Diuretics, n (%)11 (48)6 (38)5 (71)0.1930
ARNI, n (%)2 (9)2 (13)0 (0)1.0000
SGLT2I, n (%)5 (22)4 (25)1 (14)1.0000
CCB, n (%)3 (13)0 (0)3 (19)0.5257

ACEI, angiotensin-converting enzyme inhibitor; ALT, alanine aminotransferase; ARB, angiotensin II receptor blocker; ARNI, angiotensin receptor neprilysin inhibitor; AST, aspartate aminotransferase; BMI, body mass index; CCB, calcium channel blocker; CK, creatine kinase; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; Hb, haemoglobin; Hs-TnT, high-sensitivity troponin T; LDL-C, low-density lipoprotein cholesterol; MRA, mineralocorticoid receptor antagonist; NT-proBNP, N-terminal pro–B-type natriuretic peptide; NYHA, New York Heart Association; SBP, systolic blood pressure; SGLT2, sodium-glucose co-transporter 2.

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