Table 1.

Summary of the physico-chemical characteristics of the reference nanoparticles used in the study.

Au5nma
RLS-03
Au30nma
RLS-10
SiO2a
RLS-01-02
WC/Co
#5561HW
BaSO4b
NM-220
CeO2b
NM-212
Core compositionGoldGoldSilicon dioxideTungsten carbide-cobalt (8%.wt Co)Barium Sulfate (Barite)Cerium Dioxide (Cerianite)
Primary particle size by TEM (nm)4.83220<200 nm31.513.7
MorphologySphericalSphericalSphericalIrregular, some sphericalIrregular, some sphericalIrregular, edged, not spherical
Hydrodynamic diameter (nm). Data are presented as the mean ± the standard deviation591.2 ± 99.4720.2 ± 292.668.1 ± 6.51253 ± 43441 ± 3 (at 10 µg/ml)392 ± 116 (at 10 µg/ml)
PDI0.40.50.50.7610.5
Zeta potential (mV)−11.6 ± 3.9−4.81 ± 0.6−11.4 ± 0.5−10.3 ± 1.2−11.6 ± 0.8−10.7 ± 1.0
Surface area (m2/g)n.t.n.t.n.t.5–833.027.0
Au5nma
RLS-03
Au30nma
RLS-10
SiO2a
RLS-01-02
WC/Co
#5561HW
BaSO4b
NM-220
CeO2b
NM-212
Core compositionGoldGoldSilicon dioxideTungsten carbide-cobalt (8%.wt Co)Barium Sulfate (Barite)Cerium Dioxide (Cerianite)
Primary particle size by TEM (nm)4.83220<200 nm31.513.7
MorphologySphericalSphericalSphericalIrregular, some sphericalIrregular, some sphericalIrregular, edged, not spherical
Hydrodynamic diameter (nm). Data are presented as the mean ± the standard deviation591.2 ± 99.4720.2 ± 292.668.1 ± 6.51253 ± 43441 ± 3 (at 10 µg/ml)392 ± 116 (at 10 µg/ml)
PDI0.40.50.50.7610.5
Zeta potential (mV)−11.6 ± 3.9−4.81 ± 0.6−11.4 ± 0.5−10.3 ± 1.2−11.6 ± 0.8−10.7 ± 1.0
Surface area (m2/g)n.t.n.t.n.t.5–833.027.0

aFull physico-chemical characterization data has been published by the JRC in 2018 (9).

bFull physico-chemical characterization data was published in 2021 (14).

n.t., not tested.

The primary particle size and surface area of WC/Co nanoparticles was provided by the manufacturer (NanoAmor).

Table 1.

Summary of the physico-chemical characteristics of the reference nanoparticles used in the study.

Au5nma
RLS-03
Au30nma
RLS-10
SiO2a
RLS-01-02
WC/Co
#5561HW
BaSO4b
NM-220
CeO2b
NM-212
Core compositionGoldGoldSilicon dioxideTungsten carbide-cobalt (8%.wt Co)Barium Sulfate (Barite)Cerium Dioxide (Cerianite)
Primary particle size by TEM (nm)4.83220<200 nm31.513.7
MorphologySphericalSphericalSphericalIrregular, some sphericalIrregular, some sphericalIrregular, edged, not spherical
Hydrodynamic diameter (nm). Data are presented as the mean ± the standard deviation591.2 ± 99.4720.2 ± 292.668.1 ± 6.51253 ± 43441 ± 3 (at 10 µg/ml)392 ± 116 (at 10 µg/ml)
PDI0.40.50.50.7610.5
Zeta potential (mV)−11.6 ± 3.9−4.81 ± 0.6−11.4 ± 0.5−10.3 ± 1.2−11.6 ± 0.8−10.7 ± 1.0
Surface area (m2/g)n.t.n.t.n.t.5–833.027.0
Au5nma
RLS-03
Au30nma
RLS-10
SiO2a
RLS-01-02
WC/Co
#5561HW
BaSO4b
NM-220
CeO2b
NM-212
Core compositionGoldGoldSilicon dioxideTungsten carbide-cobalt (8%.wt Co)Barium Sulfate (Barite)Cerium Dioxide (Cerianite)
Primary particle size by TEM (nm)4.83220<200 nm31.513.7
MorphologySphericalSphericalSphericalIrregular, some sphericalIrregular, some sphericalIrregular, edged, not spherical
Hydrodynamic diameter (nm). Data are presented as the mean ± the standard deviation591.2 ± 99.4720.2 ± 292.668.1 ± 6.51253 ± 43441 ± 3 (at 10 µg/ml)392 ± 116 (at 10 µg/ml)
PDI0.40.50.50.7610.5
Zeta potential (mV)−11.6 ± 3.9−4.81 ± 0.6−11.4 ± 0.5−10.3 ± 1.2−11.6 ± 0.8−10.7 ± 1.0
Surface area (m2/g)n.t.n.t.n.t.5–833.027.0

aFull physico-chemical characterization data has been published by the JRC in 2018 (9).

bFull physico-chemical characterization data was published in 2021 (14).

n.t., not tested.

The primary particle size and surface area of WC/Co nanoparticles was provided by the manufacturer (NanoAmor).

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