Table 1.

Sick day rules of the German Society of Endocrinology.

Adults
Slight injury, straining evening events, activity exceeding the usualPossibly add 5-10 mg HC
Infection with mild to moderate illness without fever or significant distress (severe physical stress), severe pain, significant stress (bereavement, exam, wedding), dental procedures, minor outpatient proceduresDouble daily dose, possibly add 5-10 mg HC in the evening
Acute illness and/or fever with severe feeling of illnessTriple daily dose or alternatively 30-20-10 mg HC (at daily dose ≤ 20 mg).
Urgently seek medical help!
Persistent vomiting/diarrhoea or high fever (>39 °C) with severe feeling of illness100 mg HC (or other GC) as a self-injection i.m., s.c., or i.v.
Seek medical attention immediately!
Children
Mild mental or physical stress eg, competition, tournament, long hiking tour, long exam such as Abi exam or final exam, light dental treatment (eg, filling), emotional stress (bereavement, wedding)Additional intake of a single dose, such as the midday or evening dose corresponding to the event
Mild infection with temperature < 38.5 °C and mild feeling of illnessDouble daily dose
Illness with fever > 38.5 °C>38.5 °C triple daily dose, >39.5 °C quadruple daily dose, dose increase until recovery, then return to standard dose within 1-2 days
In case of severe feeling of illness (regardless of temperature), reduction of general condition or change of consciousness, shock, traumai.m. or s.c. application of HC: Infants: 25 mg, nursery and primary school age: 50 mg, adolescents: 100 mg (alternative: Suppositories, not for diarrhoea!) seek medical attention after injection. Possibly continuation of HC therapy 100 mg/m2/24 h i.v. and IV therapy with NaCl 0.9%, glucose)
If oral intake is not possible (eg, due to gastrointestinal infection with vomiting)i.m. or s.c. application of HC: Infants: 25 mg, nursery and primary school age: 50 mg, adolescents: 100 mg (alternative: GC Suppository,100 mg, not for diarrhoea!
Seek medical attention after injection!
Adults
Slight injury, straining evening events, activity exceeding the usualPossibly add 5-10 mg HC
Infection with mild to moderate illness without fever or significant distress (severe physical stress), severe pain, significant stress (bereavement, exam, wedding), dental procedures, minor outpatient proceduresDouble daily dose, possibly add 5-10 mg HC in the evening
Acute illness and/or fever with severe feeling of illnessTriple daily dose or alternatively 30-20-10 mg HC (at daily dose ≤ 20 mg).
Urgently seek medical help!
Persistent vomiting/diarrhoea or high fever (>39 °C) with severe feeling of illness100 mg HC (or other GC) as a self-injection i.m., s.c., or i.v.
Seek medical attention immediately!
Children
Mild mental or physical stress eg, competition, tournament, long hiking tour, long exam such as Abi exam or final exam, light dental treatment (eg, filling), emotional stress (bereavement, wedding)Additional intake of a single dose, such as the midday or evening dose corresponding to the event
Mild infection with temperature < 38.5 °C and mild feeling of illnessDouble daily dose
Illness with fever > 38.5 °C>38.5 °C triple daily dose, >39.5 °C quadruple daily dose, dose increase until recovery, then return to standard dose within 1-2 days
In case of severe feeling of illness (regardless of temperature), reduction of general condition or change of consciousness, shock, traumai.m. or s.c. application of HC: Infants: 25 mg, nursery and primary school age: 50 mg, adolescents: 100 mg (alternative: Suppositories, not for diarrhoea!) seek medical attention after injection. Possibly continuation of HC therapy 100 mg/m2/24 h i.v. and IV therapy with NaCl 0.9%, glucose)
If oral intake is not possible (eg, due to gastrointestinal infection with vomiting)i.m. or s.c. application of HC: Infants: 25 mg, nursery and primary school age: 50 mg, adolescents: 100 mg (alternative: GC Suppository,100 mg, not for diarrhoea!
Seek medical attention after injection!

Abbreviations: GC, glucocorticoid; HC, hydrocortisone; i.m., intramuscular; i.v., intravenous; NaCl, sodium chloride; s.c., subcutaneous.

Table 1.

Sick day rules of the German Society of Endocrinology.

Adults
Slight injury, straining evening events, activity exceeding the usualPossibly add 5-10 mg HC
Infection with mild to moderate illness without fever or significant distress (severe physical stress), severe pain, significant stress (bereavement, exam, wedding), dental procedures, minor outpatient proceduresDouble daily dose, possibly add 5-10 mg HC in the evening
Acute illness and/or fever with severe feeling of illnessTriple daily dose or alternatively 30-20-10 mg HC (at daily dose ≤ 20 mg).
Urgently seek medical help!
Persistent vomiting/diarrhoea or high fever (>39 °C) with severe feeling of illness100 mg HC (or other GC) as a self-injection i.m., s.c., or i.v.
Seek medical attention immediately!
Children
Mild mental or physical stress eg, competition, tournament, long hiking tour, long exam such as Abi exam or final exam, light dental treatment (eg, filling), emotional stress (bereavement, wedding)Additional intake of a single dose, such as the midday or evening dose corresponding to the event
Mild infection with temperature < 38.5 °C and mild feeling of illnessDouble daily dose
Illness with fever > 38.5 °C>38.5 °C triple daily dose, >39.5 °C quadruple daily dose, dose increase until recovery, then return to standard dose within 1-2 days
In case of severe feeling of illness (regardless of temperature), reduction of general condition or change of consciousness, shock, traumai.m. or s.c. application of HC: Infants: 25 mg, nursery and primary school age: 50 mg, adolescents: 100 mg (alternative: Suppositories, not for diarrhoea!) seek medical attention after injection. Possibly continuation of HC therapy 100 mg/m2/24 h i.v. and IV therapy with NaCl 0.9%, glucose)
If oral intake is not possible (eg, due to gastrointestinal infection with vomiting)i.m. or s.c. application of HC: Infants: 25 mg, nursery and primary school age: 50 mg, adolescents: 100 mg (alternative: GC Suppository,100 mg, not for diarrhoea!
Seek medical attention after injection!
Adults
Slight injury, straining evening events, activity exceeding the usualPossibly add 5-10 mg HC
Infection with mild to moderate illness without fever or significant distress (severe physical stress), severe pain, significant stress (bereavement, exam, wedding), dental procedures, minor outpatient proceduresDouble daily dose, possibly add 5-10 mg HC in the evening
Acute illness and/or fever with severe feeling of illnessTriple daily dose or alternatively 30-20-10 mg HC (at daily dose ≤ 20 mg).
Urgently seek medical help!
Persistent vomiting/diarrhoea or high fever (>39 °C) with severe feeling of illness100 mg HC (or other GC) as a self-injection i.m., s.c., or i.v.
Seek medical attention immediately!
Children
Mild mental or physical stress eg, competition, tournament, long hiking tour, long exam such as Abi exam or final exam, light dental treatment (eg, filling), emotional stress (bereavement, wedding)Additional intake of a single dose, such as the midday or evening dose corresponding to the event
Mild infection with temperature < 38.5 °C and mild feeling of illnessDouble daily dose
Illness with fever > 38.5 °C>38.5 °C triple daily dose, >39.5 °C quadruple daily dose, dose increase until recovery, then return to standard dose within 1-2 days
In case of severe feeling of illness (regardless of temperature), reduction of general condition or change of consciousness, shock, traumai.m. or s.c. application of HC: Infants: 25 mg, nursery and primary school age: 50 mg, adolescents: 100 mg (alternative: Suppositories, not for diarrhoea!) seek medical attention after injection. Possibly continuation of HC therapy 100 mg/m2/24 h i.v. and IV therapy with NaCl 0.9%, glucose)
If oral intake is not possible (eg, due to gastrointestinal infection with vomiting)i.m. or s.c. application of HC: Infants: 25 mg, nursery and primary school age: 50 mg, adolescents: 100 mg (alternative: GC Suppository,100 mg, not for diarrhoea!
Seek medical attention after injection!

Abbreviations: GC, glucocorticoid; HC, hydrocortisone; i.m., intramuscular; i.v., intravenous; NaCl, sodium chloride; s.c., subcutaneous.

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