Table 2.
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Frequency of alterations in the subcellular compartments of neural cells in the forebrain and midbrain of Gallus domesticus E10 embryos exposed to pyriproxyfen.

Forebrain
Midbrain
Cell structureAlterations0.00 mg/l0.01 mg/l10 mg/l0.00 mg/l0.01 mg/l10 mg/l
Cell membranesMembrane dilatation+++++++++
Membrane rupture++++++++++
Cytoplasmic vacuolation+++++++++++
MitochondriaMembrane dilatation+++++++++++
Loss of cristae++++++++++
NucleusPerinuclear space dilatation++++++++++++++
Endoplasmic reticulumCisternae dilatation++++++++++++
Golgi bodiesCisternae dilatation-++++++++
Forebrain
Midbrain
Cell structureAlterations0.00 mg/l0.01 mg/l10 mg/l0.00 mg/l0.01 mg/l10 mg/l
Cell membranesMembrane dilatation+++++++++
Membrane rupture++++++++++
Cytoplasmic vacuolation+++++++++++
MitochondriaMembrane dilatation+++++++++++
Loss of cristae++++++++++
NucleusPerinuclear space dilatation++++++++++++++
Endoplasmic reticulumCisternae dilatation++++++++++++
Golgi bodiesCisternae dilatation-++++++++

Frequency: − (0%), + (1%–25%), ++ (26%–50%), +++ (51%–75%), ++++ (76%–100%); n = 3 brains/12 micrographs per brain vesicle/PPF concentration.

Table 2.
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Frequency of alterations in the subcellular compartments of neural cells in the forebrain and midbrain of Gallus domesticus E10 embryos exposed to pyriproxyfen.

Forebrain
Midbrain
Cell structureAlterations0.00 mg/l0.01 mg/l10 mg/l0.00 mg/l0.01 mg/l10 mg/l
Cell membranesMembrane dilatation+++++++++
Membrane rupture++++++++++
Cytoplasmic vacuolation+++++++++++
MitochondriaMembrane dilatation+++++++++++
Loss of cristae++++++++++
NucleusPerinuclear space dilatation++++++++++++++
Endoplasmic reticulumCisternae dilatation++++++++++++
Golgi bodiesCisternae dilatation-++++++++
Forebrain
Midbrain
Cell structureAlterations0.00 mg/l0.01 mg/l10 mg/l0.00 mg/l0.01 mg/l10 mg/l
Cell membranesMembrane dilatation+++++++++
Membrane rupture++++++++++
Cytoplasmic vacuolation+++++++++++
MitochondriaMembrane dilatation+++++++++++
Loss of cristae++++++++++
NucleusPerinuclear space dilatation++++++++++++++
Endoplasmic reticulumCisternae dilatation++++++++++++
Golgi bodiesCisternae dilatation-++++++++

Frequency: − (0%), + (1%–25%), ++ (26%–50%), +++ (51%–75%), ++++ (76%–100%); n = 3 brains/12 micrographs per brain vesicle/PPF concentration.

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