Table 1.

Importance factor for the reversibility of damage in subcellular compartments of the brain of Gallus domesticus embryos exposed to pyriproxyfen

Importance factor and damage reversibilitySubcellular compartments alterationsReferences
(1) Easily reversible
  • Dilatation of endoplasmic reticulum cisterns

  • Dilatation of Golgi cisterns

  • Dilatation of cell membranes

Whetsell and Bunge (1969); Escande-Geraud et al. (1988); Boissy et al. (1991); Radulescu et al. (2007)
(2) Generally reversible
  • Cytoplasmic vacuolization

  • Dilatation of mitochondrial membrane

  • Dilatation of perinuclear space

Hackenbrock (1966); Henics and Wheatley (1999); Shaiken and Opekun (2014)
(3) Irreversible
  • Cell membrane rupture

  • Loss of mitochondrial cristae

Röth et al. (1980); Misfeld et al. (1998)
Importance factor and damage reversibilitySubcellular compartments alterationsReferences
(1) Easily reversible
  • Dilatation of endoplasmic reticulum cisterns

  • Dilatation of Golgi cisterns

  • Dilatation of cell membranes

Whetsell and Bunge (1969); Escande-Geraud et al. (1988); Boissy et al. (1991); Radulescu et al. (2007)
(2) Generally reversible
  • Cytoplasmic vacuolization

  • Dilatation of mitochondrial membrane

  • Dilatation of perinuclear space

Hackenbrock (1966); Henics and Wheatley (1999); Shaiken and Opekun (2014)
(3) Irreversible
  • Cell membrane rupture

  • Loss of mitochondrial cristae

Röth et al. (1980); Misfeld et al. (1998)
Table 1.

Importance factor for the reversibility of damage in subcellular compartments of the brain of Gallus domesticus embryos exposed to pyriproxyfen

Importance factor and damage reversibilitySubcellular compartments alterationsReferences
(1) Easily reversible
  • Dilatation of endoplasmic reticulum cisterns

  • Dilatation of Golgi cisterns

  • Dilatation of cell membranes

Whetsell and Bunge (1969); Escande-Geraud et al. (1988); Boissy et al. (1991); Radulescu et al. (2007)
(2) Generally reversible
  • Cytoplasmic vacuolization

  • Dilatation of mitochondrial membrane

  • Dilatation of perinuclear space

Hackenbrock (1966); Henics and Wheatley (1999); Shaiken and Opekun (2014)
(3) Irreversible
  • Cell membrane rupture

  • Loss of mitochondrial cristae

Röth et al. (1980); Misfeld et al. (1998)
Importance factor and damage reversibilitySubcellular compartments alterationsReferences
(1) Easily reversible
  • Dilatation of endoplasmic reticulum cisterns

  • Dilatation of Golgi cisterns

  • Dilatation of cell membranes

Whetsell and Bunge (1969); Escande-Geraud et al. (1988); Boissy et al. (1991); Radulescu et al. (2007)
(2) Generally reversible
  • Cytoplasmic vacuolization

  • Dilatation of mitochondrial membrane

  • Dilatation of perinuclear space

Hackenbrock (1966); Henics and Wheatley (1999); Shaiken and Opekun (2014)
(3) Irreversible
  • Cell membrane rupture

  • Loss of mitochondrial cristae

Röth et al. (1980); Misfeld et al. (1998)
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