Table 3 Open in new tab HR-PQCT I vs...

	Left radius	Left tibia
	Mean ± SD	Mean ± SD	HR-PQCT I—HR-PQCT II [95% CI]	HR-PQCT I—HR-PQCT II [95% CI]	R²	Mean ± SD	Mean ± SD	HR-PQCT I—HR-PQCT II [95% CI]	HR-PQCT I—HR-PQCT II [95% CI]	R²
BV/TV	0.203 ± 0.044	0.169 ± 0.047	0.034^b [−0.005, 0.072]	16.6 [−2.2, 35.5]	0.73	0.228 ± 0.042	0.181 ± 0.050	0.047^b [0.007, 0.088]	20.7 [3.0, 38.5]	0.73
pBV/TV	0.073 ± 0.032	0.111 ± 0.043	−0.038^b [−0.070, −0.006]	−52.3 [−96.0, −8.5]	0.83	0.084 ± 0.029	0.133 ± 0.047	−0.049 [−0.084, −0.014]^b	−58.6 [−100.1, −17.2]	0.83
rBV/TV	0.130 ± 0.021	0.058 ± 0.015	0.072^b [0.056, 0.088]	55.4 [43.4, 67.5]	0.48	0.145 ± 0.026	0.048 ± 0.012	0.096^b [0.079, 0.114]	66.5 [54.4, 78.7]	0.37
aBV/TV	0.079 ± 0.025	0.105 ± 0.036	−0.026^b [−0.052, 0.000]	−32.9 [−65.8, −0.1]	0.80	0.084 ± 0.021	0.123 ± 0.044	−0.039^b [−0.069, −0.009]	−46.6 [−83.0, −10.3]	0.84
pBV/BV	0.347 ± 0.095	0.643 ± 0.101	−0.296^b [0.213, 0.379]	−85.4 [−109.3, −61.5]	0.68	0.361 ± 0.087	0.716 ± 0.093	−0.356^b [−0.435, −0.276]	−98.5 [−120.5, −76.6]	0.70
rBV/BV	0.653 ± 0.095	0.357 ± 0.0101	0.296^b [−0.304, -0.021]	45.3 [32.6, 58.0]	0.68	0.639 ± 0.087	0.284 ± 0.093	0.356^b [0.76, 0.435]	55.6 [43.2, 68.0]	0.70
pTb.N	1.213 ± 0.171	1.376 ± 0.165	−0.162^b [−0.304, −0.021]	−13.4 [−25.0, −1.7]	0.82	1.305 ± 0.123	1.393 ± 0.128	−0.088^b [−0.198, 0.023]	−6.7 [−15.2, 1.8]	0.62
rTb.N	1.638 ± 0.105	1.394 ± 0.118	0.244^b [0.150, 0.338]	14.9 [9.1, 20.6]	0.60	1.762 ± 0.130	1.275 ± 0.101	0.487^b [0.384, 0.589]	27.6 [21.8, 33.4]	0.33
pTb.Th	0.223 ± 0.008	0.212 ± 0.009	0.011 [−0.001, 0.023]	4.9 [−0.6, 10.4]	0.44	0.222 ± 0.011	0.220 ± 0.015	0.001^a [−0.010, 0.013]	0.6 [−4.5, 5.8]	0.77
rTb.Th	0.223 ± 0.007	0.189 ± 0.011	0.034^b [0.026, 0.042]	15.2 [11.9, 18.6]	0.47	0.217 ± 0.005	0.197 ± 0.011	0.020^b [0.012, 0.027]	9.0 [5.7, 12.4]	0.53
pTb.S	0.171 ± 0.012	0.193 ± 0.026	−0.022^b [−0.039, −0.005]	−12.6 [−22.5, −2.7]	0.40	0.162 ± 0.011	0.212 ± 0.028	−0.050^a [−0.069, −0.031]	−31.0 [−42.6, −19.3]	0.66
rTb.l	0.699 ± 0.034	0.681 ± 0.024	0.018^b [−0.007, 0.042]	2.6 [−0.9, 6.0]	0.70	0.658 ± 0.016	0.686 ± 0.016	−0.029^a [−0.043, −0.015]	−4.4 [−6.5, −2.2]	0.70
R-R Junc.D^c	2.050 ± 0.430	0.939 ± 0.323	1.111^b [0.791, 1.432]	54.2 [38.6, 69.8]	0.54	2.554 ± 0.583	0.638 ± 0.216	1.916^b [1.528, 2.303]	75.0 [59.8, 90.2]	0.35
P-R Junc.D^c	2.297 ± 0.752	2.758 ± 0.754	−0.461^a [−1.095, 0.173]	−20.1 [−47.7, 7.5]	0.63	2.947 ± 0.651	2.435 ± 0.485	0.512^a [0.007, 1.017]	17.4 [0.2, 34.5]	0.10
P-P Junc.D^c	1.185 ± 0.459	1.905 ± 0.622	−0.721^b [−1.181, −0.261]	−60.8 [−99.7, −22.0]	0.80	1.487 ± 0.385	1.898 ± 0.439	−0.411^b [−0.774, −0.048]	−27.7 [−52.1, −3.2]	0.55
PR Ratio	0.565 ± 0.245	2.038 ± 0.945	−1.473^b [−2.054, −0.892]	−260.9 [−363.8, −158.0]	0.78	0.593 ± 0.223	2.869 ± 1.165	−2.276^b [−3.015, −1.537]	−383.6 [−508.2, −259.1]	0.64
PR N Ratio	0.740 ± 0.089	0.989 ± 0.112	−0.249^b [−0.334, −0.164]	−33.6 [−45.1, −22.1]	0.84	0.744 ± 0.081	1.097 ± 0.115	−0.353^b [−0.441, −0.265]	−47.4 [−59.3, −35.6]	0.64

Left radius

Left tibia

HR-PQCT I^c

HR-PQCT II^c

Absolute difference

% Difference

Coefficient of determination

HR-PQCT I^c

HR-PQCT II^c

Absolute Difference

% Difference

Coefficient of determination

Mean ± SD

HR-PQCT I—HR-PQCT II [95% CI]

R²

Mean ± SD

HR-PQCT I—HR-PQCT II [95% CI]

R²

BV/TV

0.203 ± 0.044

0.169 ± 0.047

0.034^b
[−0.005, 0.072]

16.6 [−2.2, 35.5]

0.73

0.228 ± 0.042

0.181 ± 0.050

0.047^b [0.007, 0.088]

20.7 [3.0, 38.5]

0.73

pBV/TV

0.073 ± 0.032

0.111 ± 0.043

−0.038^b
[−0.070, −0.006]

−52.3 [−96.0, −8.5]

0.83

0.084 ± 0.029

0.133 ± 0.047

−0.049
[−0.084, −0.014]^b

−58.6 [−100.1, −17.2]

0.83

rBV/TV

0.130 ± 0.021

0.058 ± 0.015

0.072^b [0.056, 0.088]

55.4 [43.4, 67.5]

0.48

0.145 ± 0.026

0.048 ± 0.012

0.096^b [0.079, 0.114]

66.5 [54.4, 78.7]

0.37

aBV/TV

0.079 ± 0.025

0.105 ± 0.036

−0.026^b
[−0.052, 0.000]

−32.9 [−65.8, −0.1]

0.80

0.084 ± 0.021

0.123 ± 0.044

−0.039^b
[−0.069, −0.009]

−46.6 [−83.0, −10.3]

0.84

pBV/BV

0.347 ± 0.095

0.643 ± 0.101

−0.296^b [0.213, 0.379]

−85.4 [−109.3, −61.5]

0.68

0.361 ± 0.087

0.716 ± 0.093

−0.356^b
[−0.435, −0.276]

−98.5 [−120.5, −76.6]

0.70

rBV/BV

0.653 ± 0.095

0.357 ± 0.0101

0.296^b
[−0.304,
-0.021]

45.3 [32.6, 58.0]

0.68

0.639 ± 0.087

0.284 ± 0.093

0.356^b [0.76, 0.435]

55.6 [43.2, 68.0]

0.70

pTb.N

1.213 ± 0.171

1.376 ± 0.165

−0.162^b
[−0.304, −0.021]

−13.4 [−25.0, −1.7]

0.82

1.305 ± 0.123

1.393 ± 0.128

−0.088^b
[−0.198, 0.023]

−6.7 [−15.2, 1.8]

0.62

rTb.N

1.638 ± 0.105

1.394 ± 0.118

0.244^b [0.150, 0.338]

14.9 [9.1, 20.6]

0.60

1.762 ± 0.130

1.275 ± 0.101

0.487^b [0.384, 0.589]

27.6 [21.8, 33.4]

0.33

pTb.Th

0.223 ± 0.008

0.212 ± 0.009

0.011 [−0.001, 0.023]

4.9 [−0.6, 10.4]

0.44

0.222 ± 0.011

0.220 ± 0.015

0.001^a
[−0.010, 0.013]

0.6 [−4.5, 5.8]

0.77

rTb.Th

0.223 ± 0.007

0.189 ± 0.011

0.034^b [0.026, 0.042]

15.2 [11.9, 18.6]

0.47

0.217 ± 0.005

0.197 ± 0.011

0.020^b [0.012, 0.027]

9.0 [5.7, 12.4]

0.53

pTb.S

0.171 ± 0.012

0.193 ± 0.026

−0.022^b
[−0.039, −0.005]

−12.6 [−22.5, −2.7]

0.40

0.162 ± 0.011

0.212 ± 0.028

−0.050^a
[−0.069, −0.031]

−31.0 [−42.6, −19.3]

0.66

rTb.l

0.699 ± 0.034

0.681 ± 0.024

0.018^b
[−0.007, 0.042]

2.6 [−0.9, 6.0]

0.70

0.658 ± 0.016

0.686 ± 0.016

−0.029^a
[−0.043, −0.015]

−4.4 [−6.5, −2.2]

0.70

R-R Junc.D^c

2.050 ± 0.430

0.939 ± 0.323

1.111^b [0.791, 1.432]

54.2 [38.6, 69.8]

0.54

2.554 ± 0.583

0.638 ± 0.216

1.916^b [1.528, 2.303]

75.0 [59.8, 90.2]

0.35

P-R Junc.D^c

2.297 ± 0.752

2.758 ± 0.754

−0.461^a
[−1.095, 0.173]

−20.1 [−47.7, 7.5]

0.63

2.947 ± 0.651

2.435 ± 0.485

0.512^a [0.007, 1.017]

17.4 [0.2, 34.5]

0.10

P-P Junc.D^c

1.185 ± 0.459

1.905 ± 0.622

−0.721^b
[−1.181, −0.261]

−60.8 [−99.7, −22.0]

0.80

1.487 ± 0.385

1.898 ± 0.439

−0.411^b
[−0.774, −0.048]

−27.7 [−52.1, −3.2]

0.55

PR Ratio

0.565 ± 0.245

2.038 ± 0.945

−1.473^b
[−2.054, −0.892]

−260.9
[−363.8, −158.0]

0.78

0.593 ± 0.223

2.869 ± 1.165

−2.276^b
[−3.015, −1.537]

−383.6
[−508.2, −259.1]

0.64

PR N Ratio

0.740 ± 0.089

0.989 ± 0.112

−0.249^b
[−0.334, −0.164]

−33.6 [−45.1, −22.1]

0.84

0.744 ± 0.081

1.097 ± 0.115

−0.353^b
[−0.441, −0.265]

−47.4 [−59.3, −35.6]

0.64

	Left radius	Left tibia
	Mean ± SD	Mean ± SD	HR-PQCT I—HR-PQCT II [95% CI]	HR-PQCT I—HR-PQCT II [95% CI]	R²	Mean ± SD	Mean ± SD	HR-PQCT I—HR-PQCT II [95% CI]	HR-PQCT I—HR-PQCT II [95% CI]	R²
BV/TV	0.203 ± 0.044	0.169 ± 0.047	0.034^b [−0.005, 0.072]	16.6 [−2.2, 35.5]	0.73	0.228 ± 0.042	0.181 ± 0.050	0.047^b [0.007, 0.088]	20.7 [3.0, 38.5]	0.73
pBV/TV	0.073 ± 0.032	0.111 ± 0.043	−0.038^b [−0.070, −0.006]	−52.3 [−96.0, −8.5]	0.83	0.084 ± 0.029	0.133 ± 0.047	−0.049 [−0.084, −0.014]^b	−58.6 [−100.1, −17.2]	0.83
rBV/TV	0.130 ± 0.021	0.058 ± 0.015	0.072^b [0.056, 0.088]	55.4 [43.4, 67.5]	0.48	0.145 ± 0.026	0.048 ± 0.012	0.096^b [0.079, 0.114]	66.5 [54.4, 78.7]	0.37
aBV/TV	0.079 ± 0.025	0.105 ± 0.036	−0.026^b [−0.052, 0.000]	−32.9 [−65.8, −0.1]	0.80	0.084 ± 0.021	0.123 ± 0.044	−0.039^b [−0.069, −0.009]	−46.6 [−83.0, −10.3]	0.84
pBV/BV	0.347 ± 0.095	0.643 ± 0.101	−0.296^b [0.213, 0.379]	−85.4 [−109.3, −61.5]	0.68	0.361 ± 0.087	0.716 ± 0.093	−0.356^b [−0.435, −0.276]	−98.5 [−120.5, −76.6]	0.70
rBV/BV	0.653 ± 0.095	0.357 ± 0.0101	0.296^b [−0.304, -0.021]	45.3 [32.6, 58.0]	0.68	0.639 ± 0.087	0.284 ± 0.093	0.356^b [0.76, 0.435]	55.6 [43.2, 68.0]	0.70
pTb.N	1.213 ± 0.171	1.376 ± 0.165	−0.162^b [−0.304, −0.021]	−13.4 [−25.0, −1.7]	0.82	1.305 ± 0.123	1.393 ± 0.128	−0.088^b [−0.198, 0.023]	−6.7 [−15.2, 1.8]	0.62
rTb.N	1.638 ± 0.105	1.394 ± 0.118	0.244^b [0.150, 0.338]	14.9 [9.1, 20.6]	0.60	1.762 ± 0.130	1.275 ± 0.101	0.487^b [0.384, 0.589]	27.6 [21.8, 33.4]	0.33
pTb.Th	0.223 ± 0.008	0.212 ± 0.009	0.011 [−0.001, 0.023]	4.9 [−0.6, 10.4]	0.44	0.222 ± 0.011	0.220 ± 0.015	0.001^a [−0.010, 0.013]	0.6 [−4.5, 5.8]	0.77
rTb.Th	0.223 ± 0.007	0.189 ± 0.011	0.034^b [0.026, 0.042]	15.2 [11.9, 18.6]	0.47	0.217 ± 0.005	0.197 ± 0.011	0.020^b [0.012, 0.027]	9.0 [5.7, 12.4]	0.53
pTb.S	0.171 ± 0.012	0.193 ± 0.026	−0.022^b [−0.039, −0.005]	−12.6 [−22.5, −2.7]	0.40	0.162 ± 0.011	0.212 ± 0.028	−0.050^a [−0.069, −0.031]	−31.0 [−42.6, −19.3]	0.66
rTb.l	0.699 ± 0.034	0.681 ± 0.024	0.018^b [−0.007, 0.042]	2.6 [−0.9, 6.0]	0.70	0.658 ± 0.016	0.686 ± 0.016	−0.029^a [−0.043, −0.015]	−4.4 [−6.5, −2.2]	0.70
R-R Junc.D^c	2.050 ± 0.430	0.939 ± 0.323	1.111^b [0.791, 1.432]	54.2 [38.6, 69.8]	0.54	2.554 ± 0.583	0.638 ± 0.216	1.916^b [1.528, 2.303]	75.0 [59.8, 90.2]	0.35
P-R Junc.D^c	2.297 ± 0.752	2.758 ± 0.754	−0.461^a [−1.095, 0.173]	−20.1 [−47.7, 7.5]	0.63	2.947 ± 0.651	2.435 ± 0.485	0.512^a [0.007, 1.017]	17.4 [0.2, 34.5]	0.10
P-P Junc.D^c	1.185 ± 0.459	1.905 ± 0.622	−0.721^b [−1.181, −0.261]	−60.8 [−99.7, −22.0]	0.80	1.487 ± 0.385	1.898 ± 0.439	−0.411^b [−0.774, −0.048]	−27.7 [−52.1, −3.2]	0.55
PR Ratio	0.565 ± 0.245	2.038 ± 0.945	−1.473^b [−2.054, −0.892]	−260.9 [−363.8, −158.0]	0.78	0.593 ± 0.223	2.869 ± 1.165	−2.276^b [−3.015, −1.537]	−383.6 [−508.2, −259.1]	0.64
PR N Ratio	0.740 ± 0.089	0.989 ± 0.112	−0.249^b [−0.334, −0.164]	−33.6 [−45.1, −22.1]	0.84	0.744 ± 0.081	1.097 ± 0.115	−0.353^b [−0.441, −0.265]	−47.4 [−59.3, −35.6]	0.64

Left radius

Left tibia

HR-PQCT I^c

HR-PQCT II^c

Absolute difference

% Difference

Coefficient of determination

HR-PQCT I^c

HR-PQCT II^c

Absolute Difference

% Difference

Coefficient of determination

Mean ± SD

HR-PQCT I—HR-PQCT II [95% CI]

R²

Mean ± SD

HR-PQCT I—HR-PQCT II [95% CI]

R²

BV/TV

0.203 ± 0.044

0.169 ± 0.047

0.034^b
[−0.005, 0.072]

16.6 [−2.2, 35.5]

0.73

0.228 ± 0.042

0.181 ± 0.050

0.047^b [0.007, 0.088]

20.7 [3.0, 38.5]

0.73

pBV/TV

0.073 ± 0.032

0.111 ± 0.043

−0.038^b
[−0.070, −0.006]

−52.3 [−96.0, −8.5]

0.83

0.084 ± 0.029

0.133 ± 0.047

−0.049
[−0.084, −0.014]^b

−58.6 [−100.1, −17.2]

0.83

rBV/TV

0.130 ± 0.021

0.058 ± 0.015

0.072^b [0.056, 0.088]

55.4 [43.4, 67.5]

0.48

0.145 ± 0.026

0.048 ± 0.012

0.096^b [0.079, 0.114]

66.5 [54.4, 78.7]

0.37

aBV/TV

0.079 ± 0.025

0.105 ± 0.036

−0.026^b
[−0.052, 0.000]

−32.9 [−65.8, −0.1]

0.80

0.084 ± 0.021

0.123 ± 0.044

−0.039^b
[−0.069, −0.009]

−46.6 [−83.0, −10.3]

0.84

pBV/BV

0.347 ± 0.095

0.643 ± 0.101

−0.296^b [0.213, 0.379]

−85.4 [−109.3, −61.5]

0.68

0.361 ± 0.087

0.716 ± 0.093

−0.356^b
[−0.435, −0.276]

−98.5 [−120.5, −76.6]

0.70

rBV/BV

0.653 ± 0.095

0.357 ± 0.0101

0.296^b
[−0.304,
-0.021]

45.3 [32.6, 58.0]

0.68

0.639 ± 0.087

0.284 ± 0.093

0.356^b [0.76, 0.435]

55.6 [43.2, 68.0]

0.70

pTb.N

1.213 ± 0.171

1.376 ± 0.165

−0.162^b
[−0.304, −0.021]

−13.4 [−25.0, −1.7]

0.82

1.305 ± 0.123

1.393 ± 0.128

−0.088^b
[−0.198, 0.023]

−6.7 [−15.2, 1.8]

0.62

rTb.N

1.638 ± 0.105

1.394 ± 0.118

0.244^b [0.150, 0.338]

14.9 [9.1, 20.6]

0.60

1.762 ± 0.130

1.275 ± 0.101

0.487^b [0.384, 0.589]

27.6 [21.8, 33.4]

0.33

pTb.Th

0.223 ± 0.008

0.212 ± 0.009

0.011 [−0.001, 0.023]

4.9 [−0.6, 10.4]

0.44

0.222 ± 0.011

0.220 ± 0.015

0.001^a
[−0.010, 0.013]

0.6 [−4.5, 5.8]

0.77

rTb.Th

0.223 ± 0.007

0.189 ± 0.011

0.034^b [0.026, 0.042]

15.2 [11.9, 18.6]

0.47

0.217 ± 0.005

0.197 ± 0.011

0.020^b [0.012, 0.027]

9.0 [5.7, 12.4]

0.53

pTb.S

0.171 ± 0.012

0.193 ± 0.026

−0.022^b
[−0.039, −0.005]

−12.6 [−22.5, −2.7]

0.40

0.162 ± 0.011

0.212 ± 0.028

−0.050^a
[−0.069, −0.031]

−31.0 [−42.6, −19.3]

0.66

rTb.l

0.699 ± 0.034

0.681 ± 0.024

0.018^b
[−0.007, 0.042]

2.6 [−0.9, 6.0]

0.70

0.658 ± 0.016

0.686 ± 0.016

−0.029^a
[−0.043, −0.015]

−4.4 [−6.5, −2.2]

0.70

R-R Junc.D^c

2.050 ± 0.430

0.939 ± 0.323

1.111^b [0.791, 1.432]

54.2 [38.6, 69.8]

0.54

2.554 ± 0.583

0.638 ± 0.216

1.916^b [1.528, 2.303]

75.0 [59.8, 90.2]

0.35

P-R Junc.D^c

2.297 ± 0.752

2.758 ± 0.754

−0.461^a
[−1.095, 0.173]

−20.1 [−47.7, 7.5]

0.63

2.947 ± 0.651

2.435 ± 0.485

0.512^a [0.007, 1.017]

17.4 [0.2, 34.5]

0.10

P-P Junc.D^c

1.185 ± 0.459

1.905 ± 0.622

−0.721^b
[−1.181, −0.261]

−60.8 [−99.7, −22.0]

0.80

1.487 ± 0.385

1.898 ± 0.439

−0.411^b
[−0.774, −0.048]

−27.7 [−52.1, −3.2]

0.55

PR Ratio

0.565 ± 0.245

2.038 ± 0.945

−1.473^b
[−2.054, −0.892]

−260.9
[−363.8, −158.0]

0.78

0.593 ± 0.223

2.869 ± 1.165

−2.276^b
[−3.015, −1.537]

−383.6
[−508.2, −259.1]

0.64

PR N Ratio

0.740 ± 0.089

0.989 ± 0.112

−0.249^b
[−0.334, −0.164]

−33.6 [−45.1, −22.1]

0.84

0.744 ± 0.081

1.097 ± 0.115

−0.353^b
[−0.441, −0.265]

−47.4 [−59.3, −35.6]

0.64

Table 3

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HR-PQCT I vs HR-PQCT II ITS morphological parameters in the distal radius and tibia with difference and correlation coefficients calculated.

	Left radius					Left tibia
	HR-PQCT I^c	HR-PQCT II^c	Absolute difference	% Difference	Coefficient of determination	HR-PQCT I^c	HR-PQCT II^c	Absolute Difference	% Difference	Coefficient of determination
	Mean ± SD	Mean ± SD	HR-PQCT I—HR-PQCT II [95% CI]	HR-PQCT I—HR-PQCT II [95% CI]	R²	Mean ± SD	Mean ± SD	HR-PQCT I—HR-PQCT II [95% CI]	HR-PQCT I—HR-PQCT II [95% CI]	R²
BV/TV	0.203 ± 0.044	0.169 ± 0.047	0.034^b [−0.005, 0.072]	16.6 [−2.2, 35.5]	0.73	0.228 ± 0.042	0.181 ± 0.050	0.047^b [0.007, 0.088]	20.7 [3.0, 38.5]	0.73
pBV/TV	0.073 ± 0.032	0.111 ± 0.043	−0.038^b [−0.070, −0.006]	−52.3 [−96.0, −8.5]	0.83	0.084 ± 0.029	0.133 ± 0.047	−0.049 [−0.084, −0.014]^b	−58.6 [−100.1, −17.2]	0.83
rBV/TV	0.130 ± 0.021	0.058 ± 0.015	0.072^b [0.056, 0.088]	55.4 [43.4, 67.5]	0.48	0.145 ± 0.026	0.048 ± 0.012	0.096^b [0.079, 0.114]	66.5 [54.4, 78.7]	0.37
aBV/TV	0.079 ± 0.025	0.105 ± 0.036	−0.026^b [−0.052, 0.000]	−32.9 [−65.8, −0.1]	0.80	0.084 ± 0.021	0.123 ± 0.044	−0.039^b [−0.069, −0.009]	−46.6 [−83.0, −10.3]	0.84
pBV/BV	0.347 ± 0.095	0.643 ± 0.101	−0.296^b [0.213, 0.379]	−85.4 [−109.3, −61.5]	0.68	0.361 ± 0.087	0.716 ± 0.093	−0.356^b [−0.435, −0.276]	−98.5 [−120.5, −76.6]	0.70
rBV/BV	0.653 ± 0.095	0.357 ± 0.0101	0.296^b [−0.304, -0.021]	45.3 [32.6, 58.0]	0.68	0.639 ± 0.087	0.284 ± 0.093	0.356^b [0.76, 0.435]	55.6 [43.2, 68.0]	0.70
pTb.N	1.213 ± 0.171	1.376 ± 0.165	−0.162^b [−0.304, −0.021]	−13.4 [−25.0, −1.7]	0.82	1.305 ± 0.123	1.393 ± 0.128	−0.088^b [−0.198, 0.023]	−6.7 [−15.2, 1.8]	0.62
rTb.N	1.638 ± 0.105	1.394 ± 0.118	0.244^b [0.150, 0.338]	14.9 [9.1, 20.6]	0.60	1.762 ± 0.130	1.275 ± 0.101	0.487^b [0.384, 0.589]	27.6 [21.8, 33.4]	0.33
pTb.Th	0.223 ± 0.008	0.212 ± 0.009	0.011 [−0.001, 0.023]	4.9 [−0.6, 10.4]	0.44	0.222 ± 0.011	0.220 ± 0.015	0.001^a [−0.010, 0.013]	0.6 [−4.5, 5.8]	0.77
rTb.Th	0.223 ± 0.007	0.189 ± 0.011	0.034^b [0.026, 0.042]	15.2 [11.9, 18.6]	0.47	0.217 ± 0.005	0.197 ± 0.011	0.020^b [0.012, 0.027]	9.0 [5.7, 12.4]	0.53
pTb.S	0.171 ± 0.012	0.193 ± 0.026	−0.022^b [−0.039, −0.005]	−12.6 [−22.5, −2.7]	0.40	0.162 ± 0.011	0.212 ± 0.028	−0.050^a [−0.069, −0.031]	−31.0 [−42.6, −19.3]	0.66
rTb.l	0.699 ± 0.034	0.681 ± 0.024	0.018^b [−0.007, 0.042]	2.6 [−0.9, 6.0]	0.70	0.658 ± 0.016	0.686 ± 0.016	−0.029^a [−0.043, −0.015]	−4.4 [−6.5, −2.2]	0.70
R-R Junc.D^c	2.050 ± 0.430	0.939 ± 0.323	1.111^b [0.791, 1.432]	54.2 [38.6, 69.8]	0.54	2.554 ± 0.583	0.638 ± 0.216	1.916^b [1.528, 2.303]	75.0 [59.8, 90.2]	0.35
P-R Junc.D^c	2.297 ± 0.752	2.758 ± 0.754	−0.461^a [−1.095, 0.173]	−20.1 [−47.7, 7.5]	0.63	2.947 ± 0.651	2.435 ± 0.485	0.512^a [0.007, 1.017]	17.4 [0.2, 34.5]	0.10
P-P Junc.D^c	1.185 ± 0.459	1.905 ± 0.622	−0.721^b [−1.181, −0.261]	−60.8 [−99.7, −22.0]	0.80	1.487 ± 0.385	1.898 ± 0.439	−0.411^b [−0.774, −0.048]	−27.7 [−52.1, −3.2]	0.55
PR Ratio	0.565 ± 0.245	2.038 ± 0.945	−1.473^b [−2.054, −0.892]	−260.9 [−363.8, −158.0]	0.78	0.593 ± 0.223	2.869 ± 1.165	−2.276^b [−3.015, −1.537]	−383.6 [−508.2, −259.1]	0.64
PR N Ratio	0.740 ± 0.089	0.989 ± 0.112	−0.249^b [−0.334, −0.164]	−33.6 [−45.1, −22.1]	0.84	0.744 ± 0.081	1.097 ± 0.115	−0.353^b [−0.441, −0.265]	−47.4 [−59.3, −35.6]	0.64

	Left radius					Left tibia
	HR-PQCT I^c	HR-PQCT II^c	Absolute difference	% Difference	Coefficient of determination	HR-PQCT I^c	HR-PQCT II^c	Absolute Difference	% Difference	Coefficient of determination
	Mean ± SD	Mean ± SD	HR-PQCT I—HR-PQCT II [95% CI]	HR-PQCT I—HR-PQCT II [95% CI]	R²	Mean ± SD	Mean ± SD	HR-PQCT I—HR-PQCT II [95% CI]	HR-PQCT I—HR-PQCT II [95% CI]	R²
BV/TV	0.203 ± 0.044	0.169 ± 0.047	0.034^b [−0.005, 0.072]	16.6 [−2.2, 35.5]	0.73	0.228 ± 0.042	0.181 ± 0.050	0.047^b [0.007, 0.088]	20.7 [3.0, 38.5]	0.73
pBV/TV	0.073 ± 0.032	0.111 ± 0.043	−0.038^b [−0.070, −0.006]	−52.3 [−96.0, −8.5]	0.83	0.084 ± 0.029	0.133 ± 0.047	−0.049 [−0.084, −0.014]^b	−58.6 [−100.1, −17.2]	0.83
rBV/TV	0.130 ± 0.021	0.058 ± 0.015	0.072^b [0.056, 0.088]	55.4 [43.4, 67.5]	0.48	0.145 ± 0.026	0.048 ± 0.012	0.096^b [0.079, 0.114]	66.5 [54.4, 78.7]	0.37
aBV/TV	0.079 ± 0.025	0.105 ± 0.036	−0.026^b [−0.052, 0.000]	−32.9 [−65.8, −0.1]	0.80	0.084 ± 0.021	0.123 ± 0.044	−0.039^b [−0.069, −0.009]	−46.6 [−83.0, −10.3]	0.84
pBV/BV	0.347 ± 0.095	0.643 ± 0.101	−0.296^b [0.213, 0.379]	−85.4 [−109.3, −61.5]	0.68	0.361 ± 0.087	0.716 ± 0.093	−0.356^b [−0.435, −0.276]	−98.5 [−120.5, −76.6]	0.70
rBV/BV	0.653 ± 0.095	0.357 ± 0.0101	0.296^b [−0.304, -0.021]	45.3 [32.6, 58.0]	0.68	0.639 ± 0.087	0.284 ± 0.093	0.356^b [0.76, 0.435]	55.6 [43.2, 68.0]	0.70
pTb.N	1.213 ± 0.171	1.376 ± 0.165	−0.162^b [−0.304, −0.021]	−13.4 [−25.0, −1.7]	0.82	1.305 ± 0.123	1.393 ± 0.128	−0.088^b [−0.198, 0.023]	−6.7 [−15.2, 1.8]	0.62
rTb.N	1.638 ± 0.105	1.394 ± 0.118	0.244^b [0.150, 0.338]	14.9 [9.1, 20.6]	0.60	1.762 ± 0.130	1.275 ± 0.101	0.487^b [0.384, 0.589]	27.6 [21.8, 33.4]	0.33
pTb.Th	0.223 ± 0.008	0.212 ± 0.009	0.011 [−0.001, 0.023]	4.9 [−0.6, 10.4]	0.44	0.222 ± 0.011	0.220 ± 0.015	0.001^a [−0.010, 0.013]	0.6 [−4.5, 5.8]	0.77
rTb.Th	0.223 ± 0.007	0.189 ± 0.011	0.034^b [0.026, 0.042]	15.2 [11.9, 18.6]	0.47	0.217 ± 0.005	0.197 ± 0.011	0.020^b [0.012, 0.027]	9.0 [5.7, 12.4]	0.53
pTb.S	0.171 ± 0.012	0.193 ± 0.026	−0.022^b [−0.039, −0.005]	−12.6 [−22.5, −2.7]	0.40	0.162 ± 0.011	0.212 ± 0.028	−0.050^a [−0.069, −0.031]	−31.0 [−42.6, −19.3]	0.66
rTb.l	0.699 ± 0.034	0.681 ± 0.024	0.018^b [−0.007, 0.042]	2.6 [−0.9, 6.0]	0.70	0.658 ± 0.016	0.686 ± 0.016	−0.029^a [−0.043, −0.015]	−4.4 [−6.5, −2.2]	0.70
R-R Junc.D^c	2.050 ± 0.430	0.939 ± 0.323	1.111^b [0.791, 1.432]	54.2 [38.6, 69.8]	0.54	2.554 ± 0.583	0.638 ± 0.216	1.916^b [1.528, 2.303]	75.0 [59.8, 90.2]	0.35
P-R Junc.D^c	2.297 ± 0.752	2.758 ± 0.754	−0.461^a [−1.095, 0.173]	−20.1 [−47.7, 7.5]	0.63	2.947 ± 0.651	2.435 ± 0.485	0.512^a [0.007, 1.017]	17.4 [0.2, 34.5]	0.10
P-P Junc.D^c	1.185 ± 0.459	1.905 ± 0.622	−0.721^b [−1.181, −0.261]	−60.8 [−99.7, −22.0]	0.80	1.487 ± 0.385	1.898 ± 0.439	−0.411^b [−0.774, −0.048]	−27.7 [−52.1, −3.2]	0.55
PR Ratio	0.565 ± 0.245	2.038 ± 0.945	−1.473^b [−2.054, −0.892]	−260.9 [−363.8, −158.0]	0.78	0.593 ± 0.223	2.869 ± 1.165	−2.276^b [−3.015, −1.537]	−383.6 [−508.2, −259.1]	0.64
PR N Ratio	0.740 ± 0.089	0.989 ± 0.112	−0.249^b [−0.334, −0.164]	−33.6 [−45.1, −22.1]	0.84	0.744 ± 0.081	1.097 ± 0.115	−0.353^b [−0.441, −0.265]	−47.4 [−59.3, −35.6]	0.64

^aP< .05, ^bP < .0001; Abbreviations: ^cHR-pQCT, high-resolution peripheral quantitative computed tomography; P-P Junc.D, plate-to-plate junction density; P-R Junc.D, plate-to-rod junction density; R-R Junc.D, rod-to-rod junction density.

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