| . | 1 h group (n = 407) . | 2 h group (n = 394) . |
|---|---|---|
| Baseline characteristics | ||
| Age, years | 72.0 (58.0–82.0) | 72.0 (57.3–81.8) |
| Female | 179 (44.0) | 175 (44.4) |
| Chest pain | 357 (87.7) | 345 (87.6) |
| Time from symptom onset, h | 1.5 (1.0–3.0) | 1.5 (1.0–3.0) |
| Risk factors | ||
| Hypertension | 284 (69.8) | 275 (69.8) |
| Hyperlipidemia | 215 (52.8) | 209 (53.0) |
| Diabetes mellitus | 110 (27.0) | 105 (26.6) |
| Family history of premature CADa | 77 (19.0) | 73 (18.6) |
| Current smokinga | 73 (18.0) | 71 (18.1) |
| Previous MIa | 41 (10.1) | 38 (9.7) |
| Previous VSA | 43 (10.6) | 43 (10.9) |
| Previous PCI | 78 (19.2) | 75 (19.0) |
| Medical history risk | ||
| Highly suspicious | 116 (28.5) | 113 (28.7) |
| Moderately suspicious | 215 (52.8) | 207 (52.5) |
| Slightly suspicious | 76 (18.7) | 74 (18.8) |
| ECG findings | ||
| New ST depression | 25 (6.1) | 23 (5.8) |
| New T-wave inversion | 22 (5.4) | 20 (5.1) |
| Physiological parameters | ||
| Systolic BP, mmHg | 143 (126–162) | 143 (127–163) |
| Diastolic BP, mmHg | 83 (75–94) | 84 (75–94) |
| Heart rate, bpm | 75 (67–86) | 75 (67–85) |
| Creatinine clearanceb,c | 63.2 (43.5–93.4) | 63.1 (43.5–93.5) |
| Hs-cTnI concentration at presentation, ng/l | ||
| Type 1 MI | 62.0 (16.0–432.0) | 62.0 (16.0–432.0) |
| Type 2 MI | 32.0 (13.8–47.8) | 32.0 (13.8–47.8) |
| MI due to coronary vasospasm | 17.0 (8.0–40.0) | 17.0 (8.0–40.0) |
| no MI | 4.0 (2.0–8.5) | 4.0 (2.0–8.5) |
| Risk scores | ||
| ADAPT | 1 (1–3) | 1 (1–3) |
| EDACS | 19 (14–22) | 19 (14–22) |
| GRACE | 91 (63–108) | 95 (69–115) |
| HEART | 4 (3–5) | 4 (3–5) |
| . | 1 h group (n = 407) . | 2 h group (n = 394) . |
|---|---|---|
| Baseline characteristics | ||
| Age, years | 72.0 (58.0–82.0) | 72.0 (57.3–81.8) |
| Female | 179 (44.0) | 175 (44.4) |
| Chest pain | 357 (87.7) | 345 (87.6) |
| Time from symptom onset, h | 1.5 (1.0–3.0) | 1.5 (1.0–3.0) |
| Risk factors | ||
| Hypertension | 284 (69.8) | 275 (69.8) |
| Hyperlipidemia | 215 (52.8) | 209 (53.0) |
| Diabetes mellitus | 110 (27.0) | 105 (26.6) |
| Family history of premature CADa | 77 (19.0) | 73 (18.6) |
| Current smokinga | 73 (18.0) | 71 (18.1) |
| Previous MIa | 41 (10.1) | 38 (9.7) |
| Previous VSA | 43 (10.6) | 43 (10.9) |
| Previous PCI | 78 (19.2) | 75 (19.0) |
| Medical history risk | ||
| Highly suspicious | 116 (28.5) | 113 (28.7) |
| Moderately suspicious | 215 (52.8) | 207 (52.5) |
| Slightly suspicious | 76 (18.7) | 74 (18.8) |
| ECG findings | ||
| New ST depression | 25 (6.1) | 23 (5.8) |
| New T-wave inversion | 22 (5.4) | 20 (5.1) |
| Physiological parameters | ||
| Systolic BP, mmHg | 143 (126–162) | 143 (127–163) |
| Diastolic BP, mmHg | 83 (75–94) | 84 (75–94) |
| Heart rate, bpm | 75 (67–86) | 75 (67–85) |
| Creatinine clearanceb,c | 63.2 (43.5–93.4) | 63.1 (43.5–93.5) |
| Hs-cTnI concentration at presentation, ng/l | ||
| Type 1 MI | 62.0 (16.0–432.0) | 62.0 (16.0–432.0) |
| Type 2 MI | 32.0 (13.8–47.8) | 32.0 (13.8–47.8) |
| MI due to coronary vasospasm | 17.0 (8.0–40.0) | 17.0 (8.0–40.0) |
| no MI | 4.0 (2.0–8.5) | 4.0 (2.0–8.5) |
| Risk scores | ||
| ADAPT | 1 (1–3) | 1 (1–3) |
| EDACS | 19 (14–22) | 19 (14–22) |
| GRACE | 91 (63–108) | 95 (69–115) |
| HEART | 4 (3–5) | 4 (3–5) |
Values are median (interquartile range) or n (%).
Data missing in one patient.
ml/min/1.73 m2.
Data missing in two patients.
BP, blood pressure; CABG, coronary artery bypass grafting; CAD, coronary artery disease; MI, myocardial infarction; PCI, percutaneous coronary intervention; VSA, vasospastic angina.
| . | 1 h group (n = 407) . | 2 h group (n = 394) . |
|---|---|---|
| Baseline characteristics | ||
| Age, years | 72.0 (58.0–82.0) | 72.0 (57.3–81.8) |
| Female | 179 (44.0) | 175 (44.4) |
| Chest pain | 357 (87.7) | 345 (87.6) |
| Time from symptom onset, h | 1.5 (1.0–3.0) | 1.5 (1.0–3.0) |
| Risk factors | ||
| Hypertension | 284 (69.8) | 275 (69.8) |
| Hyperlipidemia | 215 (52.8) | 209 (53.0) |
| Diabetes mellitus | 110 (27.0) | 105 (26.6) |
| Family history of premature CADa | 77 (19.0) | 73 (18.6) |
| Current smokinga | 73 (18.0) | 71 (18.1) |
| Previous MIa | 41 (10.1) | 38 (9.7) |
| Previous VSA | 43 (10.6) | 43 (10.9) |
| Previous PCI | 78 (19.2) | 75 (19.0) |
| Medical history risk | ||
| Highly suspicious | 116 (28.5) | 113 (28.7) |
| Moderately suspicious | 215 (52.8) | 207 (52.5) |
| Slightly suspicious | 76 (18.7) | 74 (18.8) |
| ECG findings | ||
| New ST depression | 25 (6.1) | 23 (5.8) |
| New T-wave inversion | 22 (5.4) | 20 (5.1) |
| Physiological parameters | ||
| Systolic BP, mmHg | 143 (126–162) | 143 (127–163) |
| Diastolic BP, mmHg | 83 (75–94) | 84 (75–94) |
| Heart rate, bpm | 75 (67–86) | 75 (67–85) |
| Creatinine clearanceb,c | 63.2 (43.5–93.4) | 63.1 (43.5–93.5) |
| Hs-cTnI concentration at presentation, ng/l | ||
| Type 1 MI | 62.0 (16.0–432.0) | 62.0 (16.0–432.0) |
| Type 2 MI | 32.0 (13.8–47.8) | 32.0 (13.8–47.8) |
| MI due to coronary vasospasm | 17.0 (8.0–40.0) | 17.0 (8.0–40.0) |
| no MI | 4.0 (2.0–8.5) | 4.0 (2.0–8.5) |
| Risk scores | ||
| ADAPT | 1 (1–3) | 1 (1–3) |
| EDACS | 19 (14–22) | 19 (14–22) |
| GRACE | 91 (63–108) | 95 (69–115) |
| HEART | 4 (3–5) | 4 (3–5) |
| . | 1 h group (n = 407) . | 2 h group (n = 394) . |
|---|---|---|
| Baseline characteristics | ||
| Age, years | 72.0 (58.0–82.0) | 72.0 (57.3–81.8) |
| Female | 179 (44.0) | 175 (44.4) |
| Chest pain | 357 (87.7) | 345 (87.6) |
| Time from symptom onset, h | 1.5 (1.0–3.0) | 1.5 (1.0–3.0) |
| Risk factors | ||
| Hypertension | 284 (69.8) | 275 (69.8) |
| Hyperlipidemia | 215 (52.8) | 209 (53.0) |
| Diabetes mellitus | 110 (27.0) | 105 (26.6) |
| Family history of premature CADa | 77 (19.0) | 73 (18.6) |
| Current smokinga | 73 (18.0) | 71 (18.1) |
| Previous MIa | 41 (10.1) | 38 (9.7) |
| Previous VSA | 43 (10.6) | 43 (10.9) |
| Previous PCI | 78 (19.2) | 75 (19.0) |
| Medical history risk | ||
| Highly suspicious | 116 (28.5) | 113 (28.7) |
| Moderately suspicious | 215 (52.8) | 207 (52.5) |
| Slightly suspicious | 76 (18.7) | 74 (18.8) |
| ECG findings | ||
| New ST depression | 25 (6.1) | 23 (5.8) |
| New T-wave inversion | 22 (5.4) | 20 (5.1) |
| Physiological parameters | ||
| Systolic BP, mmHg | 143 (126–162) | 143 (127–163) |
| Diastolic BP, mmHg | 83 (75–94) | 84 (75–94) |
| Heart rate, bpm | 75 (67–86) | 75 (67–85) |
| Creatinine clearanceb,c | 63.2 (43.5–93.4) | 63.1 (43.5–93.5) |
| Hs-cTnI concentration at presentation, ng/l | ||
| Type 1 MI | 62.0 (16.0–432.0) | 62.0 (16.0–432.0) |
| Type 2 MI | 32.0 (13.8–47.8) | 32.0 (13.8–47.8) |
| MI due to coronary vasospasm | 17.0 (8.0–40.0) | 17.0 (8.0–40.0) |
| no MI | 4.0 (2.0–8.5) | 4.0 (2.0–8.5) |
| Risk scores | ||
| ADAPT | 1 (1–3) | 1 (1–3) |
| EDACS | 19 (14–22) | 19 (14–22) |
| GRACE | 91 (63–108) | 95 (69–115) |
| HEART | 4 (3–5) | 4 (3–5) |
Values are median (interquartile range) or n (%).
Data missing in one patient.
ml/min/1.73 m2.
Data missing in two patients.
BP, blood pressure; CABG, coronary artery bypass grafting; CAD, coronary artery disease; MI, myocardial infarction; PCI, percutaneous coronary intervention; VSA, vasospastic angina.
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