Multivariable associations between soluble urokinase plasminogen activator receptor levels and the demographic, clinical, and behavioural characteristics of the cohort
| . | % Estimates . |
|---|---|
| Age | −0.004 (−0.1, 0.1) P = 0.99 |
| Male sex | −13 (−15.5, −10.4) P < 0.0001 |
| White race | 4 (0.8, 7.4) P = 0.01 |
| Educationa | 9 (6.3, 11.8) P < 0.0001 |
| Hypertension | −0.4 (−3.5, 2.8) P = 0.79 |
| Diabetes | 7.5 (4.6, 10.4) P < 0.0001 |
| Previous MI | −0.07 (−3.1, 3.1) P = 0.97 |
| Obstructive CADb | 0.8 (−2.2, 3.9) P = 0.6 |
| EF | −0.2 (−0.3, −0.1) P < 0.0001 |
| Current/former smoker | 1.2 (−1.5, 3.9) P = 0.38 |
| Alcohol consumption | −0.8 (−2.6, 1.1) P = 0.4 |
| BMI | −0.1 (−0.3, 0.1) P = 0.38 |
| eGFR | −0.8 (−0.9, −0.8) P < 0.0001 |
| Hs-CRPc | 0.05 (0.04, 0.06) P < 0.0001 |
| Total cholesterol | −0.07 (−0.2, 0.08) P = 0.37 |
| LDL-cholesterol | −0.003 (−0.2, 0.2) P = 0.97 |
| HDL-cholesterol | −0.2 (−0.4, −0.03) P = 0.02 |
| Triglycerides | −0.004 (−0.03, 0.03) P = 0.8 |
| . | % Estimates . |
|---|---|
| Age | −0.004 (−0.1, 0.1) P = 0.99 |
| Male sex | −13 (−15.5, −10.4) P < 0.0001 |
| White race | 4 (0.8, 7.4) P = 0.01 |
| Educationa | 9 (6.3, 11.8) P < 0.0001 |
| Hypertension | −0.4 (−3.5, 2.8) P = 0.79 |
| Diabetes | 7.5 (4.6, 10.4) P < 0.0001 |
| Previous MI | −0.07 (−3.1, 3.1) P = 0.97 |
| Obstructive CADb | 0.8 (−2.2, 3.9) P = 0.6 |
| EF | −0.2 (−0.3, −0.1) P < 0.0001 |
| Current/former smoker | 1.2 (−1.5, 3.9) P = 0.38 |
| Alcohol consumption | −0.8 (−2.6, 1.1) P = 0.4 |
| BMI | −0.1 (−0.3, 0.1) P = 0.38 |
| eGFR | −0.8 (−0.9, −0.8) P < 0.0001 |
| Hs-CRPc | 0.05 (0.04, 0.06) P < 0.0001 |
| Total cholesterol | −0.07 (−0.2, 0.08) P = 0.37 |
| LDL-cholesterol | −0.003 (−0.2, 0.2) P = 0.97 |
| HDL-cholesterol | −0.2 (−0.4, −0.03) P = 0.02 |
| Triglycerides | −0.004 (−0.03, 0.03) P = 0.8 |
MI, myocardial infarction; CAD, coronary artery disease; EF, ejection fraction; BMI, body mass index; eGFR, estimated glomerular filtration rate.
aEducation low vs. high. Low educational qualification is defined as elementary/middle school, some high school, or high-school graduate as having the highest educational qualification. High educational qualification is defined as some college education, a college degree, graduate education, or a degree as the highest educational qualification.
bObstructive CAD defined as ≥50% stenosis in ≥1 epicardial artery.
cThe association between 1% higher in hs-CRP and suPAR levels in %.
Multivariable associations between soluble urokinase plasminogen activator receptor levels and the demographic, clinical, and behavioural characteristics of the cohort
| . | % Estimates . |
|---|---|
| Age | −0.004 (−0.1, 0.1) P = 0.99 |
| Male sex | −13 (−15.5, −10.4) P < 0.0001 |
| White race | 4 (0.8, 7.4) P = 0.01 |
| Educationa | 9 (6.3, 11.8) P < 0.0001 |
| Hypertension | −0.4 (−3.5, 2.8) P = 0.79 |
| Diabetes | 7.5 (4.6, 10.4) P < 0.0001 |
| Previous MI | −0.07 (−3.1, 3.1) P = 0.97 |
| Obstructive CADb | 0.8 (−2.2, 3.9) P = 0.6 |
| EF | −0.2 (−0.3, −0.1) P < 0.0001 |
| Current/former smoker | 1.2 (−1.5, 3.9) P = 0.38 |
| Alcohol consumption | −0.8 (−2.6, 1.1) P = 0.4 |
| BMI | −0.1 (−0.3, 0.1) P = 0.38 |
| eGFR | −0.8 (−0.9, −0.8) P < 0.0001 |
| Hs-CRPc | 0.05 (0.04, 0.06) P < 0.0001 |
| Total cholesterol | −0.07 (−0.2, 0.08) P = 0.37 |
| LDL-cholesterol | −0.003 (−0.2, 0.2) P = 0.97 |
| HDL-cholesterol | −0.2 (−0.4, −0.03) P = 0.02 |
| Triglycerides | −0.004 (−0.03, 0.03) P = 0.8 |
| . | % Estimates . |
|---|---|
| Age | −0.004 (−0.1, 0.1) P = 0.99 |
| Male sex | −13 (−15.5, −10.4) P < 0.0001 |
| White race | 4 (0.8, 7.4) P = 0.01 |
| Educationa | 9 (6.3, 11.8) P < 0.0001 |
| Hypertension | −0.4 (−3.5, 2.8) P = 0.79 |
| Diabetes | 7.5 (4.6, 10.4) P < 0.0001 |
| Previous MI | −0.07 (−3.1, 3.1) P = 0.97 |
| Obstructive CADb | 0.8 (−2.2, 3.9) P = 0.6 |
| EF | −0.2 (−0.3, −0.1) P < 0.0001 |
| Current/former smoker | 1.2 (−1.5, 3.9) P = 0.38 |
| Alcohol consumption | −0.8 (−2.6, 1.1) P = 0.4 |
| BMI | −0.1 (−0.3, 0.1) P = 0.38 |
| eGFR | −0.8 (−0.9, −0.8) P < 0.0001 |
| Hs-CRPc | 0.05 (0.04, 0.06) P < 0.0001 |
| Total cholesterol | −0.07 (−0.2, 0.08) P = 0.37 |
| LDL-cholesterol | −0.003 (−0.2, 0.2) P = 0.97 |
| HDL-cholesterol | −0.2 (−0.4, −0.03) P = 0.02 |
| Triglycerides | −0.004 (−0.03, 0.03) P = 0.8 |
MI, myocardial infarction; CAD, coronary artery disease; EF, ejection fraction; BMI, body mass index; eGFR, estimated glomerular filtration rate.
aEducation low vs. high. Low educational qualification is defined as elementary/middle school, some high school, or high-school graduate as having the highest educational qualification. High educational qualification is defined as some college education, a college degree, graduate education, or a degree as the highest educational qualification.
bObstructive CAD defined as ≥50% stenosis in ≥1 epicardial artery.
cThe association between 1% higher in hs-CRP and suPAR levels in %.
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