| Variable . | All patients, n = 176 . | Patients with events, n = 67 . | Patients without events, n = 109 . | P-value . |
|---|---|---|---|---|
| Heart rate, mean ± SD, bpm | 70 ± 13 | 70 ± 14 | 69 ± 13 | 0.40 |
| Mean arterial pressure, mean ± SD, mmHg | 86 ± 11 | 84 ± 13 | 87 ± 12 | 0.69 |
| Left chambers | ||||
| LV-EDV index, mean ± SD, mL/m2 | 43 ± 16 | 46 ± 17 | 41 ± 15 | 0.10 |
| LV-ESV index, mean ± SD, mL/m2 | 16 ± 9 | 19 ± 11 | 14 ± 7 | 0.12 |
| LV SV, mean ± SD, mL/m2 | 28 ± 10 | 27 ± 10 | 29 ± 10 | 0.41 |
| LV ejection fraction, mean ± SD, % | 63 ± 9 | 62 ± 10 | 64 ± 9 | 0.20 |
| LV-GLS, mean ± SD, % | −19.5 ± 4 | −17.7 ± 5 | −18.9 ± 4 | 0.10 |
| LA volume, mL/m2, median (IQR) | 57 (37–87) | 70 (37–90) | 53 (36–72) | 0.24 |
| Average E/é, mean ± SD | 10 ± 4 | 10 ± 4 | 10 ± 4 | 0.40 |
| Right ventricle | ||||
| RV-basal diameter, mean ± SD, mm | 44 ± 7 | 47 ± 7 | 43 ± 8 | 0.007 |
| RV-mid diameter, mean ± SD, mm | 35 ± 8 | 37 ± 8 | 34 ± 8 | 0.007 |
| PASP, mean ± SD, mmHg | 39 ± 12 | 40 ± 12 | 39 ± 12 | 0.47 |
| RV end-diastolic area, mean ± SD, cm2 | 22 ± 6 | 25 ± 7 | 20 ± 6 | <0.001 |
| RV end-systolic area, mean ± SD, cm2 | 12 ± 4 | 14 ± 4 | 11 ± 4 | 0.002 |
| RV FAC, mean ± SD,% | 44 ± 13 | 43 ± 16 | 45 ± 8 | 0.41 |
| TAPSE, mean ± SD, mm | 20.6 ± 4 | 20.6 ± 4 | 20.7 ± 4 | 0.97 |
| TAPSE/PASP | 0.58 ± 0.23 | 0.57 ± 0.20 | 0.59 ± 0.25 | 0.42 |
| S′wave TDI, mean ± SD, cm/s | 10.3 ± 2 | 10.1 ± 2 | 10.6 ± 2 | 0.20 |
| TEI index, mean ± SD | 65.6 ± 22 | 67 ± 25 | 64 ± 15 | 0.48 |
| RV-FWLS, mean ± SD, % | −21.3 ± 6 | −16.9 ± 5 | −24 ± 5 | <0.001 |
| RV-GLS, mean ± SD, % | −18.1 ± 5 | −14.6 ± 5 | −20.2 ± 4 | <0.001 |
| STREI index, mean ± SD, % | 55.7 ± 17 | 43.2 ± 13 | 63.3 ± 15 | <0.001 |
| Right atrium | ||||
| RA area, mean ± SD, cm2 | 30 ± 13 | 32 ± 10 | 29 ± 13 | 0.23 |
| RA volume, median (IQR), mL/m2 | 60 (41–83) | 66 (50–98) | 53 (37–79) | 0.001 |
| IVC diameter mean ± SD (mm) | 20 ± 6 | 24 ± 6 | 20 ± 6 | 0.002 |
| Estimated RAP (IVC) | 8 (3–15) | 8 (8–15) | 8 (3–8) | 0.01 |
| RASr, median (IQR), % | 11 (7–16) | 8.7 (6–13) | 13 (10–19) | <0.001 |
| RASct, mean ± SD, % | −1.5 ± 9 | −2.8 ± 8 | −2.7 ± 6.7 | 0.40 |
| Tricuspid regurgitation | ||||
| Tricuspid annulus, mean ± SD, mm | 40 ± 7 | 41 ± 6 | 39 ± 7 | 0.23 |
| TR biplane vena contracta, mean ± SD, mm | 9.5 ± 4 | 10.1 ± 4 | 8 ± 3 | 0.001 |
| ERO, median (IQR), cm2 | 0.47 (0.35–0.67) | 0.54 (0.37–0.73) | 0.42 (0.33–0.58) | 0.001 |
| TR regurgitant volume, median (IQR), mL | 37 (29–51) | 42 (32–55) | 35 (28–43) | 0.006 |
| Variable . | All patients, n = 176 . | Patients with events, n = 67 . | Patients without events, n = 109 . | P-value . |
|---|---|---|---|---|
| Heart rate, mean ± SD, bpm | 70 ± 13 | 70 ± 14 | 69 ± 13 | 0.40 |
| Mean arterial pressure, mean ± SD, mmHg | 86 ± 11 | 84 ± 13 | 87 ± 12 | 0.69 |
| Left chambers | ||||
| LV-EDV index, mean ± SD, mL/m2 | 43 ± 16 | 46 ± 17 | 41 ± 15 | 0.10 |
| LV-ESV index, mean ± SD, mL/m2 | 16 ± 9 | 19 ± 11 | 14 ± 7 | 0.12 |
| LV SV, mean ± SD, mL/m2 | 28 ± 10 | 27 ± 10 | 29 ± 10 | 0.41 |
| LV ejection fraction, mean ± SD, % | 63 ± 9 | 62 ± 10 | 64 ± 9 | 0.20 |
| LV-GLS, mean ± SD, % | −19.5 ± 4 | −17.7 ± 5 | −18.9 ± 4 | 0.10 |
| LA volume, mL/m2, median (IQR) | 57 (37–87) | 70 (37–90) | 53 (36–72) | 0.24 |
| Average E/é, mean ± SD | 10 ± 4 | 10 ± 4 | 10 ± 4 | 0.40 |
| Right ventricle | ||||
| RV-basal diameter, mean ± SD, mm | 44 ± 7 | 47 ± 7 | 43 ± 8 | 0.007 |
| RV-mid diameter, mean ± SD, mm | 35 ± 8 | 37 ± 8 | 34 ± 8 | 0.007 |
| PASP, mean ± SD, mmHg | 39 ± 12 | 40 ± 12 | 39 ± 12 | 0.47 |
| RV end-diastolic area, mean ± SD, cm2 | 22 ± 6 | 25 ± 7 | 20 ± 6 | <0.001 |
| RV end-systolic area, mean ± SD, cm2 | 12 ± 4 | 14 ± 4 | 11 ± 4 | 0.002 |
| RV FAC, mean ± SD,% | 44 ± 13 | 43 ± 16 | 45 ± 8 | 0.41 |
| TAPSE, mean ± SD, mm | 20.6 ± 4 | 20.6 ± 4 | 20.7 ± 4 | 0.97 |
| TAPSE/PASP | 0.58 ± 0.23 | 0.57 ± 0.20 | 0.59 ± 0.25 | 0.42 |
| S′wave TDI, mean ± SD, cm/s | 10.3 ± 2 | 10.1 ± 2 | 10.6 ± 2 | 0.20 |
| TEI index, mean ± SD | 65.6 ± 22 | 67 ± 25 | 64 ± 15 | 0.48 |
| RV-FWLS, mean ± SD, % | −21.3 ± 6 | −16.9 ± 5 | −24 ± 5 | <0.001 |
| RV-GLS, mean ± SD, % | −18.1 ± 5 | −14.6 ± 5 | −20.2 ± 4 | <0.001 |
| STREI index, mean ± SD, % | 55.7 ± 17 | 43.2 ± 13 | 63.3 ± 15 | <0.001 |
| Right atrium | ||||
| RA area, mean ± SD, cm2 | 30 ± 13 | 32 ± 10 | 29 ± 13 | 0.23 |
| RA volume, median (IQR), mL/m2 | 60 (41–83) | 66 (50–98) | 53 (37–79) | 0.001 |
| IVC diameter mean ± SD (mm) | 20 ± 6 | 24 ± 6 | 20 ± 6 | 0.002 |
| Estimated RAP (IVC) | 8 (3–15) | 8 (8–15) | 8 (3–8) | 0.01 |
| RASr, median (IQR), % | 11 (7–16) | 8.7 (6–13) | 13 (10–19) | <0.001 |
| RASct, mean ± SD, % | −1.5 ± 9 | −2.8 ± 8 | −2.7 ± 6.7 | 0.40 |
| Tricuspid regurgitation | ||||
| Tricuspid annulus, mean ± SD, mm | 40 ± 7 | 41 ± 6 | 39 ± 7 | 0.23 |
| TR biplane vena contracta, mean ± SD, mm | 9.5 ± 4 | 10.1 ± 4 | 8 ± 3 | 0.001 |
| ERO, median (IQR), cm2 | 0.47 (0.35–0.67) | 0.54 (0.37–0.73) | 0.42 (0.33–0.58) | 0.001 |
| TR regurgitant volume, median (IQR), mL | 37 (29–51) | 42 (32–55) | 35 (28–43) | 0.006 |
LV, left ventricle; LV-EDV, left ventricle end-diastolic volume; LV-ESV, left ventricle end-systolic volume; LV-SV, left ventricle stroke volume; LV-GLS, left ventricle global longitudinal strain; LA, left atrium; PASP, pulmonary artery systolic pressure; TDI, Tissue Doppler imaging; RV-GLS, right ventricle global longitudinal strain, IVC, Inferior Vena Cava; RAP, right atrial pressure; RASct, right atrial contractile strain.
| Variable . | All patients, n = 176 . | Patients with events, n = 67 . | Patients without events, n = 109 . | P-value . |
|---|---|---|---|---|
| Heart rate, mean ± SD, bpm | 70 ± 13 | 70 ± 14 | 69 ± 13 | 0.40 |
| Mean arterial pressure, mean ± SD, mmHg | 86 ± 11 | 84 ± 13 | 87 ± 12 | 0.69 |
| Left chambers | ||||
| LV-EDV index, mean ± SD, mL/m2 | 43 ± 16 | 46 ± 17 | 41 ± 15 | 0.10 |
| LV-ESV index, mean ± SD, mL/m2 | 16 ± 9 | 19 ± 11 | 14 ± 7 | 0.12 |
| LV SV, mean ± SD, mL/m2 | 28 ± 10 | 27 ± 10 | 29 ± 10 | 0.41 |
| LV ejection fraction, mean ± SD, % | 63 ± 9 | 62 ± 10 | 64 ± 9 | 0.20 |
| LV-GLS, mean ± SD, % | −19.5 ± 4 | −17.7 ± 5 | −18.9 ± 4 | 0.10 |
| LA volume, mL/m2, median (IQR) | 57 (37–87) | 70 (37–90) | 53 (36–72) | 0.24 |
| Average E/é, mean ± SD | 10 ± 4 | 10 ± 4 | 10 ± 4 | 0.40 |
| Right ventricle | ||||
| RV-basal diameter, mean ± SD, mm | 44 ± 7 | 47 ± 7 | 43 ± 8 | 0.007 |
| RV-mid diameter, mean ± SD, mm | 35 ± 8 | 37 ± 8 | 34 ± 8 | 0.007 |
| PASP, mean ± SD, mmHg | 39 ± 12 | 40 ± 12 | 39 ± 12 | 0.47 |
| RV end-diastolic area, mean ± SD, cm2 | 22 ± 6 | 25 ± 7 | 20 ± 6 | <0.001 |
| RV end-systolic area, mean ± SD, cm2 | 12 ± 4 | 14 ± 4 | 11 ± 4 | 0.002 |
| RV FAC, mean ± SD,% | 44 ± 13 | 43 ± 16 | 45 ± 8 | 0.41 |
| TAPSE, mean ± SD, mm | 20.6 ± 4 | 20.6 ± 4 | 20.7 ± 4 | 0.97 |
| TAPSE/PASP | 0.58 ± 0.23 | 0.57 ± 0.20 | 0.59 ± 0.25 | 0.42 |
| S′wave TDI, mean ± SD, cm/s | 10.3 ± 2 | 10.1 ± 2 | 10.6 ± 2 | 0.20 |
| TEI index, mean ± SD | 65.6 ± 22 | 67 ± 25 | 64 ± 15 | 0.48 |
| RV-FWLS, mean ± SD, % | −21.3 ± 6 | −16.9 ± 5 | −24 ± 5 | <0.001 |
| RV-GLS, mean ± SD, % | −18.1 ± 5 | −14.6 ± 5 | −20.2 ± 4 | <0.001 |
| STREI index, mean ± SD, % | 55.7 ± 17 | 43.2 ± 13 | 63.3 ± 15 | <0.001 |
| Right atrium | ||||
| RA area, mean ± SD, cm2 | 30 ± 13 | 32 ± 10 | 29 ± 13 | 0.23 |
| RA volume, median (IQR), mL/m2 | 60 (41–83) | 66 (50–98) | 53 (37–79) | 0.001 |
| IVC diameter mean ± SD (mm) | 20 ± 6 | 24 ± 6 | 20 ± 6 | 0.002 |
| Estimated RAP (IVC) | 8 (3–15) | 8 (8–15) | 8 (3–8) | 0.01 |
| RASr, median (IQR), % | 11 (7–16) | 8.7 (6–13) | 13 (10–19) | <0.001 |
| RASct, mean ± SD, % | −1.5 ± 9 | −2.8 ± 8 | −2.7 ± 6.7 | 0.40 |
| Tricuspid regurgitation | ||||
| Tricuspid annulus, mean ± SD, mm | 40 ± 7 | 41 ± 6 | 39 ± 7 | 0.23 |
| TR biplane vena contracta, mean ± SD, mm | 9.5 ± 4 | 10.1 ± 4 | 8 ± 3 | 0.001 |
| ERO, median (IQR), cm2 | 0.47 (0.35–0.67) | 0.54 (0.37–0.73) | 0.42 (0.33–0.58) | 0.001 |
| TR regurgitant volume, median (IQR), mL | 37 (29–51) | 42 (32–55) | 35 (28–43) | 0.006 |
| Variable . | All patients, n = 176 . | Patients with events, n = 67 . | Patients without events, n = 109 . | P-value . |
|---|---|---|---|---|
| Heart rate, mean ± SD, bpm | 70 ± 13 | 70 ± 14 | 69 ± 13 | 0.40 |
| Mean arterial pressure, mean ± SD, mmHg | 86 ± 11 | 84 ± 13 | 87 ± 12 | 0.69 |
| Left chambers | ||||
| LV-EDV index, mean ± SD, mL/m2 | 43 ± 16 | 46 ± 17 | 41 ± 15 | 0.10 |
| LV-ESV index, mean ± SD, mL/m2 | 16 ± 9 | 19 ± 11 | 14 ± 7 | 0.12 |
| LV SV, mean ± SD, mL/m2 | 28 ± 10 | 27 ± 10 | 29 ± 10 | 0.41 |
| LV ejection fraction, mean ± SD, % | 63 ± 9 | 62 ± 10 | 64 ± 9 | 0.20 |
| LV-GLS, mean ± SD, % | −19.5 ± 4 | −17.7 ± 5 | −18.9 ± 4 | 0.10 |
| LA volume, mL/m2, median (IQR) | 57 (37–87) | 70 (37–90) | 53 (36–72) | 0.24 |
| Average E/é, mean ± SD | 10 ± 4 | 10 ± 4 | 10 ± 4 | 0.40 |
| Right ventricle | ||||
| RV-basal diameter, mean ± SD, mm | 44 ± 7 | 47 ± 7 | 43 ± 8 | 0.007 |
| RV-mid diameter, mean ± SD, mm | 35 ± 8 | 37 ± 8 | 34 ± 8 | 0.007 |
| PASP, mean ± SD, mmHg | 39 ± 12 | 40 ± 12 | 39 ± 12 | 0.47 |
| RV end-diastolic area, mean ± SD, cm2 | 22 ± 6 | 25 ± 7 | 20 ± 6 | <0.001 |
| RV end-systolic area, mean ± SD, cm2 | 12 ± 4 | 14 ± 4 | 11 ± 4 | 0.002 |
| RV FAC, mean ± SD,% | 44 ± 13 | 43 ± 16 | 45 ± 8 | 0.41 |
| TAPSE, mean ± SD, mm | 20.6 ± 4 | 20.6 ± 4 | 20.7 ± 4 | 0.97 |
| TAPSE/PASP | 0.58 ± 0.23 | 0.57 ± 0.20 | 0.59 ± 0.25 | 0.42 |
| S′wave TDI, mean ± SD, cm/s | 10.3 ± 2 | 10.1 ± 2 | 10.6 ± 2 | 0.20 |
| TEI index, mean ± SD | 65.6 ± 22 | 67 ± 25 | 64 ± 15 | 0.48 |
| RV-FWLS, mean ± SD, % | −21.3 ± 6 | −16.9 ± 5 | −24 ± 5 | <0.001 |
| RV-GLS, mean ± SD, % | −18.1 ± 5 | −14.6 ± 5 | −20.2 ± 4 | <0.001 |
| STREI index, mean ± SD, % | 55.7 ± 17 | 43.2 ± 13 | 63.3 ± 15 | <0.001 |
| Right atrium | ||||
| RA area, mean ± SD, cm2 | 30 ± 13 | 32 ± 10 | 29 ± 13 | 0.23 |
| RA volume, median (IQR), mL/m2 | 60 (41–83) | 66 (50–98) | 53 (37–79) | 0.001 |
| IVC diameter mean ± SD (mm) | 20 ± 6 | 24 ± 6 | 20 ± 6 | 0.002 |
| Estimated RAP (IVC) | 8 (3–15) | 8 (8–15) | 8 (3–8) | 0.01 |
| RASr, median (IQR), % | 11 (7–16) | 8.7 (6–13) | 13 (10–19) | <0.001 |
| RASct, mean ± SD, % | −1.5 ± 9 | −2.8 ± 8 | −2.7 ± 6.7 | 0.40 |
| Tricuspid regurgitation | ||||
| Tricuspid annulus, mean ± SD, mm | 40 ± 7 | 41 ± 6 | 39 ± 7 | 0.23 |
| TR biplane vena contracta, mean ± SD, mm | 9.5 ± 4 | 10.1 ± 4 | 8 ± 3 | 0.001 |
| ERO, median (IQR), cm2 | 0.47 (0.35–0.67) | 0.54 (0.37–0.73) | 0.42 (0.33–0.58) | 0.001 |
| TR regurgitant volume, median (IQR), mL | 37 (29–51) | 42 (32–55) | 35 (28–43) | 0.006 |
LV, left ventricle; LV-EDV, left ventricle end-diastolic volume; LV-ESV, left ventricle end-systolic volume; LV-SV, left ventricle stroke volume; LV-GLS, left ventricle global longitudinal strain; LA, left atrium; PASP, pulmonary artery systolic pressure; TDI, Tissue Doppler imaging; RV-GLS, right ventricle global longitudinal strain, IVC, Inferior Vena Cava; RAP, right atrial pressure; RASct, right atrial contractile strain.
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