The probability LOGO statistics generated from the liver of Mgmt−/− mice treated with NDMA. The value represents the log-odds binomial probability. The 15-base sequence contexts with G→A mutations fixed at the zero position were extracted from all datasets (4 males and 4 females) and compiled with inter-individual replicate sequences included in analysis
| Position . | Frequency (%) . | Value . |
|---|---|---|
| G at -6 | 23.9 | 4.72 |
| G at -5 | 22.8 | 4.67 |
| G at -4 | 22.6 | 5.86 |
| G at -3 | 22.9 | 4.27 |
| A at -3 | 29.2 | 4.17 |
| A at -2 | 32.8 | 29.44 |
| G at -2 | 24.3 | 23.51 |
| T at -2 | 24.7 | 9.33 |
| G at -1 | 41.6 | 324 |
| A at -1 | 42.5 | 256.46 |
| G at 0 | ||
| A at 1 | 31.4 | 47.10 |
| A at 2 | 31.0 | 26.02 |
| C at 2 | 24.5 | 22.44 |
| A at 3 | 29.4 | 12.99 |
| G at 4 | 23.1 | 13.22 |
| A at 5 | 28.3 | 3.94 |
| G at 5 | 22.8 | 3.76 |
| G at 6 | 24.8 | 20.10 |
| G at 7 | 24.2 | 4.88 |
| Position . | Frequency (%) . | Value . |
|---|---|---|
| G at -6 | 23.9 | 4.72 |
| G at -5 | 22.8 | 4.67 |
| G at -4 | 22.6 | 5.86 |
| G at -3 | 22.9 | 4.27 |
| A at -3 | 29.2 | 4.17 |
| A at -2 | 32.8 | 29.44 |
| G at -2 | 24.3 | 23.51 |
| T at -2 | 24.7 | 9.33 |
| G at -1 | 41.6 | 324 |
| A at -1 | 42.5 | 256.46 |
| G at 0 | ||
| A at 1 | 31.4 | 47.10 |
| A at 2 | 31.0 | 26.02 |
| C at 2 | 24.5 | 22.44 |
| A at 3 | 29.4 | 12.99 |
| G at 4 | 23.1 | 13.22 |
| A at 5 | 28.3 | 3.94 |
| G at 5 | 22.8 | 3.76 |
| G at 6 | 24.8 | 20.10 |
| G at 7 | 24.2 | 4.88 |
The probability LOGO statistics generated from the liver of Mgmt−/− mice treated with NDMA. The value represents the log-odds binomial probability. The 15-base sequence contexts with G→A mutations fixed at the zero position were extracted from all datasets (4 males and 4 females) and compiled with inter-individual replicate sequences included in analysis
| Position . | Frequency (%) . | Value . |
|---|---|---|
| G at -6 | 23.9 | 4.72 |
| G at -5 | 22.8 | 4.67 |
| G at -4 | 22.6 | 5.86 |
| G at -3 | 22.9 | 4.27 |
| A at -3 | 29.2 | 4.17 |
| A at -2 | 32.8 | 29.44 |
| G at -2 | 24.3 | 23.51 |
| T at -2 | 24.7 | 9.33 |
| G at -1 | 41.6 | 324 |
| A at -1 | 42.5 | 256.46 |
| G at 0 | ||
| A at 1 | 31.4 | 47.10 |
| A at 2 | 31.0 | 26.02 |
| C at 2 | 24.5 | 22.44 |
| A at 3 | 29.4 | 12.99 |
| G at 4 | 23.1 | 13.22 |
| A at 5 | 28.3 | 3.94 |
| G at 5 | 22.8 | 3.76 |
| G at 6 | 24.8 | 20.10 |
| G at 7 | 24.2 | 4.88 |
| Position . | Frequency (%) . | Value . |
|---|---|---|
| G at -6 | 23.9 | 4.72 |
| G at -5 | 22.8 | 4.67 |
| G at -4 | 22.6 | 5.86 |
| G at -3 | 22.9 | 4.27 |
| A at -3 | 29.2 | 4.17 |
| A at -2 | 32.8 | 29.44 |
| G at -2 | 24.3 | 23.51 |
| T at -2 | 24.7 | 9.33 |
| G at -1 | 41.6 | 324 |
| A at -1 | 42.5 | 256.46 |
| G at 0 | ||
| A at 1 | 31.4 | 47.10 |
| A at 2 | 31.0 | 26.02 |
| C at 2 | 24.5 | 22.44 |
| A at 3 | 29.4 | 12.99 |
| G at 4 | 23.1 | 13.22 |
| A at 5 | 28.3 | 3.94 |
| G at 5 | 22.8 | 3.76 |
| G at 6 | 24.8 | 20.10 |
| G at 7 | 24.2 | 4.88 |
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