| . | All patients (4600 pts) . | Derivation (4172 pts) . | Validation (428 pts) . | P-value . |
|---|---|---|---|---|
| LVEF, % | 36.0 ± 12.9 | 35.9 ± 12.7 | 37.2 ± 14.0 | .118 |
| LVEDD, mm | 61.5 ± 10.5 | 61.6 ± 10.5 | 61.3 ± 10.5 | .525 |
| LVESD, mm | 49.5 ± 12.2 | 49.6 ± 12.1 | 49.1 ± 12.7 | .392 |
| LVEDV, mL | 175 ± 77 | 175 ± 76 | 173 ± 83 | .204 |
| LVESV, mL | 116 ± 65 | 116 ± 65 | 115 ± 69 | .476 |
| EROAmitral, cm2 | 0.33 ± 0.22 | 0.34 ± 0.23 | 0.29 ± 0.12 | <.001 |
| Vena contracta width, mm | 5.45 ± 3.16 | 5.39 ± 3.22 | 6.37 ± 1.68 | .132 |
| Regurgitant volume, mL | 44.3 ± 21.9 | 44.4 ± 22.8 | 43.6 ± 18.5 | .808 |
| MR grade, % | .343 | |||
| 1+ | 0.2 | 0.2 | 0.0 | |
| 2+ | 5.8 | 5.6 | 8.2 | |
| 3+ | 51.4 | 50.2 | 62.9 | |
| 4+ | 42.6 | 44.0 | 29.0 | |
| LA volume, mL | 118 ± 65 | 113 ± 63 | 146 ± 60 | <.001 |
| sPAP, mmHg | 48.3 ± 15.0 | 48.3 ± 15.0 | 48.3 ± 15.4 | .969 |
| RA area, cm2 | 25.1 ± 9.0 | 24.6 ± 8.6 | 28.4 ± 10.7 | <.001 |
| RVmid diameter, mm | 34.8 ± 8.7 | 35.1 ± 9.0 | 33.3 ± 7.0 | <.001 |
| TAPSE, mm | 17.2 ± 4.7 | 17.3 ± 4.7 | 16.4 ± 4.8 | <.001 |
| TR grade 3+ or 4+, % | 16.7 | 16.0 | 22.1 | .002 |
| RVPA coupling, mm/mmHg | 0.398 ± 0.248 | 0.400 ± 0.256 | 0.382 ± 0.193 | .113 |
| . | All patients (4600 pts) . | Derivation (4172 pts) . | Validation (428 pts) . | P-value . |
|---|---|---|---|---|
| LVEF, % | 36.0 ± 12.9 | 35.9 ± 12.7 | 37.2 ± 14.0 | .118 |
| LVEDD, mm | 61.5 ± 10.5 | 61.6 ± 10.5 | 61.3 ± 10.5 | .525 |
| LVESD, mm | 49.5 ± 12.2 | 49.6 ± 12.1 | 49.1 ± 12.7 | .392 |
| LVEDV, mL | 175 ± 77 | 175 ± 76 | 173 ± 83 | .204 |
| LVESV, mL | 116 ± 65 | 116 ± 65 | 115 ± 69 | .476 |
| EROAmitral, cm2 | 0.33 ± 0.22 | 0.34 ± 0.23 | 0.29 ± 0.12 | <.001 |
| Vena contracta width, mm | 5.45 ± 3.16 | 5.39 ± 3.22 | 6.37 ± 1.68 | .132 |
| Regurgitant volume, mL | 44.3 ± 21.9 | 44.4 ± 22.8 | 43.6 ± 18.5 | .808 |
| MR grade, % | .343 | |||
| 1+ | 0.2 | 0.2 | 0.0 | |
| 2+ | 5.8 | 5.6 | 8.2 | |
| 3+ | 51.4 | 50.2 | 62.9 | |
| 4+ | 42.6 | 44.0 | 29.0 | |
| LA volume, mL | 118 ± 65 | 113 ± 63 | 146 ± 60 | <.001 |
| sPAP, mmHg | 48.3 ± 15.0 | 48.3 ± 15.0 | 48.3 ± 15.4 | .969 |
| RA area, cm2 | 25.1 ± 9.0 | 24.6 ± 8.6 | 28.4 ± 10.7 | <.001 |
| RVmid diameter, mm | 34.8 ± 8.7 | 35.1 ± 9.0 | 33.3 ± 7.0 | <.001 |
| TAPSE, mm | 17.2 ± 4.7 | 17.3 ± 4.7 | 16.4 ± 4.8 | <.001 |
| TR grade 3+ or 4+, % | 16.7 | 16.0 | 22.1 | .002 |
| RVPA coupling, mm/mmHg | 0.398 ± 0.248 | 0.400 ± 0.256 | 0.382 ± 0.193 | .113 |
EROA, effective regurgitant orifice area; LVEDD, left ventricular end-diastolic diameter; LVEF, left ventricular ejection fraction; LVESD, left ventricular end-systolic diameter; LVESV, left ventricular end-systolic volume; LA, left atrial; RA, right atrial, RVmid diameter, mid-ventricular RV diameter; RVPA coupling, right ventricular to pulmonary artery coupling; sPAP, systolic pulmonary artery pressure; TAPSE, tricuspid annular plane systolic excursion; TR, tricuspid regurgitation.
| . | All patients (4600 pts) . | Derivation (4172 pts) . | Validation (428 pts) . | P-value . |
|---|---|---|---|---|
| LVEF, % | 36.0 ± 12.9 | 35.9 ± 12.7 | 37.2 ± 14.0 | .118 |
| LVEDD, mm | 61.5 ± 10.5 | 61.6 ± 10.5 | 61.3 ± 10.5 | .525 |
| LVESD, mm | 49.5 ± 12.2 | 49.6 ± 12.1 | 49.1 ± 12.7 | .392 |
| LVEDV, mL | 175 ± 77 | 175 ± 76 | 173 ± 83 | .204 |
| LVESV, mL | 116 ± 65 | 116 ± 65 | 115 ± 69 | .476 |
| EROAmitral, cm2 | 0.33 ± 0.22 | 0.34 ± 0.23 | 0.29 ± 0.12 | <.001 |
| Vena contracta width, mm | 5.45 ± 3.16 | 5.39 ± 3.22 | 6.37 ± 1.68 | .132 |
| Regurgitant volume, mL | 44.3 ± 21.9 | 44.4 ± 22.8 | 43.6 ± 18.5 | .808 |
| MR grade, % | .343 | |||
| 1+ | 0.2 | 0.2 | 0.0 | |
| 2+ | 5.8 | 5.6 | 8.2 | |
| 3+ | 51.4 | 50.2 | 62.9 | |
| 4+ | 42.6 | 44.0 | 29.0 | |
| LA volume, mL | 118 ± 65 | 113 ± 63 | 146 ± 60 | <.001 |
| sPAP, mmHg | 48.3 ± 15.0 | 48.3 ± 15.0 | 48.3 ± 15.4 | .969 |
| RA area, cm2 | 25.1 ± 9.0 | 24.6 ± 8.6 | 28.4 ± 10.7 | <.001 |
| RVmid diameter, mm | 34.8 ± 8.7 | 35.1 ± 9.0 | 33.3 ± 7.0 | <.001 |
| TAPSE, mm | 17.2 ± 4.7 | 17.3 ± 4.7 | 16.4 ± 4.8 | <.001 |
| TR grade 3+ or 4+, % | 16.7 | 16.0 | 22.1 | .002 |
| RVPA coupling, mm/mmHg | 0.398 ± 0.248 | 0.400 ± 0.256 | 0.382 ± 0.193 | .113 |
| . | All patients (4600 pts) . | Derivation (4172 pts) . | Validation (428 pts) . | P-value . |
|---|---|---|---|---|
| LVEF, % | 36.0 ± 12.9 | 35.9 ± 12.7 | 37.2 ± 14.0 | .118 |
| LVEDD, mm | 61.5 ± 10.5 | 61.6 ± 10.5 | 61.3 ± 10.5 | .525 |
| LVESD, mm | 49.5 ± 12.2 | 49.6 ± 12.1 | 49.1 ± 12.7 | .392 |
| LVEDV, mL | 175 ± 77 | 175 ± 76 | 173 ± 83 | .204 |
| LVESV, mL | 116 ± 65 | 116 ± 65 | 115 ± 69 | .476 |
| EROAmitral, cm2 | 0.33 ± 0.22 | 0.34 ± 0.23 | 0.29 ± 0.12 | <.001 |
| Vena contracta width, mm | 5.45 ± 3.16 | 5.39 ± 3.22 | 6.37 ± 1.68 | .132 |
| Regurgitant volume, mL | 44.3 ± 21.9 | 44.4 ± 22.8 | 43.6 ± 18.5 | .808 |
| MR grade, % | .343 | |||
| 1+ | 0.2 | 0.2 | 0.0 | |
| 2+ | 5.8 | 5.6 | 8.2 | |
| 3+ | 51.4 | 50.2 | 62.9 | |
| 4+ | 42.6 | 44.0 | 29.0 | |
| LA volume, mL | 118 ± 65 | 113 ± 63 | 146 ± 60 | <.001 |
| sPAP, mmHg | 48.3 ± 15.0 | 48.3 ± 15.0 | 48.3 ± 15.4 | .969 |
| RA area, cm2 | 25.1 ± 9.0 | 24.6 ± 8.6 | 28.4 ± 10.7 | <.001 |
| RVmid diameter, mm | 34.8 ± 8.7 | 35.1 ± 9.0 | 33.3 ± 7.0 | <.001 |
| TAPSE, mm | 17.2 ± 4.7 | 17.3 ± 4.7 | 16.4 ± 4.8 | <.001 |
| TR grade 3+ or 4+, % | 16.7 | 16.0 | 22.1 | .002 |
| RVPA coupling, mm/mmHg | 0.398 ± 0.248 | 0.400 ± 0.256 | 0.382 ± 0.193 | .113 |
EROA, effective regurgitant orifice area; LVEDD, left ventricular end-diastolic diameter; LVEF, left ventricular ejection fraction; LVESD, left ventricular end-systolic diameter; LVESV, left ventricular end-systolic volume; LA, left atrial; RA, right atrial, RVmid diameter, mid-ventricular RV diameter; RVPA coupling, right ventricular to pulmonary artery coupling; sPAP, systolic pulmonary artery pressure; TAPSE, tricuspid annular plane systolic excursion; TR, tricuspid regurgitation.
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