Multivariable Logistic Regression Analysis in the Propensity Score Matched Sample (n = 480): The Predictor Effects on the Prevalence of Morphometric Vertebral Fractures
| Multivariable analysis | ||
| Characteristic | OR (95% CI) | pa |
| Age | 1.09 (1.05–1.13) | <.001 |
| Previous fractures | <.001 | |
| No | 1 | |
| Yes | 4.47 (2.65–7.63) | |
| Total hip BMD, (g/cm2) | 0.18 (0.02–2.11) | .17 |
| AI group | .18 | |
| AI naïve | 1 | |
| AI treated | 0.59 (0.27–1.26) | |
| Body composition | .43 | |
| Group A: LBM− and FBM− | 1 | |
| Group B: LBM− and FBM+ | 0.45 (0.13–1.32) | |
| Group C: LBM+ and FBM− | 0.42 (0.12–1.26) | |
| Group D: LBM+ and FBM+ | 0.45 (0.19–1.05) | |
| AI group * body composition | .003 | |
| AI naïve/Group A | 1 | |
| AI treated/Group B | 11.72 (2.68–57.29) | |
| AI treated/Group C | 6.79 (1.52–33.14) | |
| AI treated/Group D | 2.2 (0.71–6.98) |
| Multivariable analysis | ||
| Characteristic | OR (95% CI) | pa |
| Age | 1.09 (1.05–1.13) | <.001 |
| Previous fractures | <.001 | |
| No | 1 | |
| Yes | 4.47 (2.65–7.63) | |
| Total hip BMD, (g/cm2) | 0.18 (0.02–2.11) | .17 |
| AI group | .18 | |
| AI naïve | 1 | |
| AI treated | 0.59 (0.27–1.26) | |
| Body composition | .43 | |
| Group A: LBM− and FBM− | 1 | |
| Group B: LBM− and FBM+ | 0.45 (0.13–1.32) | |
| Group C: LBM+ and FBM− | 0.42 (0.12–1.26) | |
| Group D: LBM+ and FBM+ | 0.45 (0.19–1.05) | |
| AI group * body composition | .003 | |
| AI naïve/Group A | 1 | |
| AI treated/Group B | 11.72 (2.68–57.29) | |
| AI treated/Group C | 6.79 (1.52–33.14) | |
| AI treated/Group D | 2.2 (0.71–6.98) |
Results are expressed as odds ratio (OR) with 95% confidence interval (95% CI).
AI = aromatase inhibitor; BMD = bone mineral density; FBM− = fat body mass < median value; FBM+ = fat body mass ≥ median value; LMB− = lean body mass < median value; LBM+ = lean body mass ≥ median value.
Likelihood ratio p value adjusted for multiple comparisons.
Multivariable Logistic Regression Analysis in the Propensity Score Matched Sample (n = 480): The Predictor Effects on the Prevalence of Morphometric Vertebral Fractures
| Multivariable analysis | ||
| Characteristic | OR (95% CI) | pa |
| Age | 1.09 (1.05–1.13) | <.001 |
| Previous fractures | <.001 | |
| No | 1 | |
| Yes | 4.47 (2.65–7.63) | |
| Total hip BMD, (g/cm2) | 0.18 (0.02–2.11) | .17 |
| AI group | .18 | |
| AI naïve | 1 | |
| AI treated | 0.59 (0.27–1.26) | |
| Body composition | .43 | |
| Group A: LBM− and FBM− | 1 | |
| Group B: LBM− and FBM+ | 0.45 (0.13–1.32) | |
| Group C: LBM+ and FBM− | 0.42 (0.12–1.26) | |
| Group D: LBM+ and FBM+ | 0.45 (0.19–1.05) | |
| AI group * body composition | .003 | |
| AI naïve/Group A | 1 | |
| AI treated/Group B | 11.72 (2.68–57.29) | |
| AI treated/Group C | 6.79 (1.52–33.14) | |
| AI treated/Group D | 2.2 (0.71–6.98) |
| Multivariable analysis | ||
| Characteristic | OR (95% CI) | pa |
| Age | 1.09 (1.05–1.13) | <.001 |
| Previous fractures | <.001 | |
| No | 1 | |
| Yes | 4.47 (2.65–7.63) | |
| Total hip BMD, (g/cm2) | 0.18 (0.02–2.11) | .17 |
| AI group | .18 | |
| AI naïve | 1 | |
| AI treated | 0.59 (0.27–1.26) | |
| Body composition | .43 | |
| Group A: LBM− and FBM− | 1 | |
| Group B: LBM− and FBM+ | 0.45 (0.13–1.32) | |
| Group C: LBM+ and FBM− | 0.42 (0.12–1.26) | |
| Group D: LBM+ and FBM+ | 0.45 (0.19–1.05) | |
| AI group * body composition | .003 | |
| AI naïve/Group A | 1 | |
| AI treated/Group B | 11.72 (2.68–57.29) | |
| AI treated/Group C | 6.79 (1.52–33.14) | |
| AI treated/Group D | 2.2 (0.71–6.98) |
Results are expressed as odds ratio (OR) with 95% confidence interval (95% CI).
AI = aromatase inhibitor; BMD = bone mineral density; FBM− = fat body mass < median value; FBM+ = fat body mass ≥ median value; LMB− = lean body mass < median value; LBM+ = lean body mass ≥ median value.
Likelihood ratio p value adjusted for multiple comparisons.
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