Subgroup analyses of skeletal and body composition parameters in controls vs POI women according to ethnicities.
| Parameters . | Control . | Caucasian POI . | p-value* . | Non-Caucasian POI . | p-value! . | Asian POI . | p-value# . | |
|---|---|---|---|---|---|---|---|---|
| BMD (g/cm2) | Spine | 1.23 (1.16, 1.34) | 1.13 (1.03, 1.23) | <.001 | 1.08 (0.98, 1.160) | <.001 | 1.02 (0.95, 1.10) | <.001 |
| FN | 1.03 ± 0.12 | 0.98 ± 0.17 | .039 | 0.92 ± 0.16 | .003 | 0.87 ± 0.15 | <.001 | |
| Total hip | 1.05 ± 0.12 | 0.99 ± 0.17 | .018 | 0.92 ± 0.13 | <.001 | 0.88 ± 0.11 | <.001 | |
| Body composition | ALMI (kg/m2) | 7.01 (6.46, 7.56) | 6.38 (5.76, 6.91) | <.001 | 5.72 (5.38, 6.30) | <.001 | 5.67 (5.38, 6.21) | <.001 |
| TFMI (kg/m2) | 9.33 (7.24, 13.79) | 10.81 (8.04, 14.09) | .122 | 9.96 (7.78, 11.76) | .91 | 7.92 (5.59, 9.80) | .15 | |
| Parameters . | Control . | Caucasian POI . | p-value* . | Non-Caucasian POI . | p-value! . | Asian POI . | p-value# . | |
|---|---|---|---|---|---|---|---|---|
| BMD (g/cm2) | Spine | 1.23 (1.16, 1.34) | 1.13 (1.03, 1.23) | <.001 | 1.08 (0.98, 1.160) | <.001 | 1.02 (0.95, 1.10) | <.001 |
| FN | 1.03 ± 0.12 | 0.98 ± 0.17 | .039 | 0.92 ± 0.16 | .003 | 0.87 ± 0.15 | <.001 | |
| Total hip | 1.05 ± 0.12 | 0.99 ± 0.17 | .018 | 0.92 ± 0.13 | <.001 | 0.88 ± 0.11 | <.001 | |
| Body composition | ALMI (kg/m2) | 7.01 (6.46, 7.56) | 6.38 (5.76, 6.91) | <.001 | 5.72 (5.38, 6.30) | <.001 | 5.67 (5.38, 6.21) | <.001 |
| TFMI (kg/m2) | 9.33 (7.24, 13.79) | 10.81 (8.04, 14.09) | .122 | 9.96 (7.78, 11.76) | .91 | 7.92 (5.59, 9.80) | .15 | |
Abbreviations: POI, premature ovarian insufficiency; BMD, bone mineral density; FN, femoral neck; ALMI, appendicular lean mass index; TFMI, total fat mass index. Bold values suggest significant p-value values.p-value*, level of significance between control, and Caucasian POI group; p-value!, level of significance between control and non-Caucasian POI and p-value#, level of significance between control and Asian POI groups.
Subgroup analyses of skeletal and body composition parameters in controls vs POI women according to ethnicities.
| Parameters . | Control . | Caucasian POI . | p-value* . | Non-Caucasian POI . | p-value! . | Asian POI . | p-value# . | |
|---|---|---|---|---|---|---|---|---|
| BMD (g/cm2) | Spine | 1.23 (1.16, 1.34) | 1.13 (1.03, 1.23) | <.001 | 1.08 (0.98, 1.160) | <.001 | 1.02 (0.95, 1.10) | <.001 |
| FN | 1.03 ± 0.12 | 0.98 ± 0.17 | .039 | 0.92 ± 0.16 | .003 | 0.87 ± 0.15 | <.001 | |
| Total hip | 1.05 ± 0.12 | 0.99 ± 0.17 | .018 | 0.92 ± 0.13 | <.001 | 0.88 ± 0.11 | <.001 | |
| Body composition | ALMI (kg/m2) | 7.01 (6.46, 7.56) | 6.38 (5.76, 6.91) | <.001 | 5.72 (5.38, 6.30) | <.001 | 5.67 (5.38, 6.21) | <.001 |
| TFMI (kg/m2) | 9.33 (7.24, 13.79) | 10.81 (8.04, 14.09) | .122 | 9.96 (7.78, 11.76) | .91 | 7.92 (5.59, 9.80) | .15 | |
| Parameters . | Control . | Caucasian POI . | p-value* . | Non-Caucasian POI . | p-value! . | Asian POI . | p-value# . | |
|---|---|---|---|---|---|---|---|---|
| BMD (g/cm2) | Spine | 1.23 (1.16, 1.34) | 1.13 (1.03, 1.23) | <.001 | 1.08 (0.98, 1.160) | <.001 | 1.02 (0.95, 1.10) | <.001 |
| FN | 1.03 ± 0.12 | 0.98 ± 0.17 | .039 | 0.92 ± 0.16 | .003 | 0.87 ± 0.15 | <.001 | |
| Total hip | 1.05 ± 0.12 | 0.99 ± 0.17 | .018 | 0.92 ± 0.13 | <.001 | 0.88 ± 0.11 | <.001 | |
| Body composition | ALMI (kg/m2) | 7.01 (6.46, 7.56) | 6.38 (5.76, 6.91) | <.001 | 5.72 (5.38, 6.30) | <.001 | 5.67 (5.38, 6.21) | <.001 |
| TFMI (kg/m2) | 9.33 (7.24, 13.79) | 10.81 (8.04, 14.09) | .122 | 9.96 (7.78, 11.76) | .91 | 7.92 (5.59, 9.80) | .15 | |
Abbreviations: POI, premature ovarian insufficiency; BMD, bone mineral density; FN, femoral neck; ALMI, appendicular lean mass index; TFMI, total fat mass index. Bold values suggest significant p-value values.p-value*, level of significance between control, and Caucasian POI group; p-value!, level of significance between control and non-Caucasian POI and p-value#, level of significance between control and Asian POI groups.
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