The number and ASR of incident and DALYs for neonatal disorders in 2019, and changing trends from 1990 to 2019
| . | 2019 . | 1990–2019 . | 2019 . | 1990–2019 . | ||
|---|---|---|---|---|---|---|
| . | Incident cases no. . | ASIR per 100 000 no. (95% UI) . | EAPC no. (95% CI) . | DALYs cases no. . | ASR-DALYs per 100 000 no. (95% UI) . | EAPC no. (95%CI) . |
| Overall | 23 532 231.9 (21 672 528.3–25 701 964.3) | 363.3 (334.6–396.8) | 0 (−0.06 to 0.06) | 185 886 390.1 (160 501 578.5–218 526 197.2) | 2828.3 (2441.6–3329.6) | −1.3 (−1.42 to 1.18) |
| Sex | ||||||
| Female | 10 878 088.4 (9 970 690.3–11 891 471.3) | 347.9 (318.8–380.3) | 0.05 (0 to 0.1) | 80 903 864.6 (70 493 249.1–93 894 238.7) | 2538.6 (2212.3–2954.3) | −1.38 (−1.48 to 1.27) |
| Male | 12 654 143.5 (11 671 263.4–13 791 272.5) | 377.8 (348.5–411.8) | −0.05 (−0.12 to 0.02) | 104 982 525.5 (89 992 179.3–124 058 674.9) | 3098.4 (2651.3–3663.6) | −1.24 (−1.38 to 1.1) |
| Age | ||||||
| <0–6 days | 4 272 672.2 (2 989 705.5–6 179 729.5) | 166 116.7 (116 236.4–240 261) | 0.49 (0.46 to 0.52) | 136 889 316.2 (116 450 062.3–162 669 807.7) | 5 322 103.3 (4 527 448–6 324 419.9) | −1.26 (−1.43 to 1.09) |
| 7–27 days | 1 652 243.5 (815 834.4–2 853 664.3) | 21 608.5 (10 669.7–37 321) | 0.58 (0.5 to 0.65) | 22 579 369.3 (19 087 688.7–26 853 350.5) | 295 299.5 (249 634.3–351 195.8) | −2.37 (−2.48 to 2.27) |
| 28–364 days | 0 | 0 | – | 7 857 828.2 (6 263 541.1–9 739 467.7) | 6453.2 (5143.9–7998.4) | −2.47 (−2.53 to 2.41) |
| 1–4 years | 0 | 0 | – | 2 942 759.6 (2 413 382.4–3 524 298.1) | 554.3 (454.6–663.9) | 0.63 (0.49 to 0.77) |
| 5–9 years | 0 | 0 | – | 1 953 414.4 (1 532 122.1–2 415 866.6) | 298.4 (234–369) | 2.52 (2.33 to 2.71) |
| 10–19 years | 0 | 0 | – | 3 588 557.3 (2 834 483.7–4 397 908) | 284.4 (224.7–348.6) | 2.76 (2.56 to 2.95) |
| 20–54 years | 0 | 0 | – | 8 573 707 (6 801 690.7–10 521 594.4) | 228.5 (181.3–280.4) | 2.7 (2.5 to 2.89) |
| 55+ years | 0 | 0 | – | 1 501 438 (1 177 534.6–1 888 579) | 54.8 (43–68.9) | 2.93 (2.6 to 3.26) |
| Socio-demographic index | ||||||
| High | 1 089 953.2 (1 054 989.2–1 127 074.9) | 219.5 (212.5–227) | 0.21 (0.11 to 0.31) | 3 455 360.4 (3 065 324.4–3 877 433.8) | 553.1 (498.2–613.1) | −1.78 (−1.85 to 1.71) |
| High-middle | 804 064.4 (555 269–1 087 955.6) | 297.9 (264.8–335.5) | 0.15 (0.13 to 0.18) | 8 524 076.6 (7 479 005.4–9 701 687.2) | 953.2 (835.9–1093.7) | −3.18 (−3.31 to 3.05) |
| Middle | 1 875 710.2 (1 290 221.3–2 558 776.4) | 328.5 (293.7–369.2) | 0 (−0.03 to 0.04) | 30 903 196.3 (26 745 267.2–35 818 934.6) | 1707.9 (1475.1–1987.3) | −2.25 (−2.42 to 2.07) |
| Low-middle | 1 591 860.7 (1 132 016.7–2 146 643.7) | 390.8 (361.4–424.6) | −0.31 (−0.37 to 0.25) | 64 958 149.6 (55 797 763.5–75 326 412.4) | 3804 (3265–4414.2) | −1.4 (−1.52 to 1.27) |
| Low | 1 510 719.9 (1 066 565.8–2 075 843.3) | 437.5 (409.1–471.4) | −0.17 (−0.22 to 0.12) | 77 939 747.9 (65 053 240.5–94 676 453.2) | 4386.5 (3671.1–5309.4) | −0.97 (−1.03 to 0.92) |
| GBD region | ||||||
| High-income Asia Pacific | 104 934.3 (101 365.4–108 619.4) | 158.4 (153.1–164) | 0.37 (0.29 to 0.44) | 320 692.9 (269 911–371 914.4) | 284.6 (248.8–322) | −2.28 (−2.43 to 2.14) |
| Central Asia | 223 779.7 (207 893.9–240 250.1) | 247.2 (229.7–265.3) | −0.36 (−0.41 to 0.31) | 1 522 378 (1 308 498.9–1 811 432.9) | 1665.1 (1430.7–1980.6) | −1.55 (−1.94 to 1.15) |
| East Asia | 2 136 197.7 (1 771 248.4–2 569 015) | 287.9 (238.8–345.9) | 0.38 (0.29 to 0.48) | 7 271 957.5 (6 376 403.8–8 313 229.2) | 786.8 (693.8–892.1) | −4.07 (−4.41 to 3.73) |
| South Asia | 66 292 44.7 (6 153 256.4–7 174 365.7) | 413.5 (383.7–447.4) | −0.27 (−0.32 to 0.22) | 71 241 073.2 (61 042 999–83 585 114.3) | 4395.1 (3765.2–5157.6) | −1.12 (−1.24–1) |
| Southeast Asia | 1 757 890.2 (1 535 711.2–2 004 844.2) | 336 (293.5–383.2) | −0.57 (−0.6 to 0.54) | 10 053 228.3 (8 349 665.4–12 031 297.8) | 1858.9 (1542.8–2234.4) | −2.2 (−2.28 to 2.12) |
| Australasia | 30 459.4 (28 790.5–32 063.1) | 172.4 (163–181.5) | 0.18 (0.09 to 0.26) | 94 676.6 (81 362.6–108 214.8) | 455.4 (391.4–519.4) | −1.66 (−1.78 to 1.54) |
| Caribbean | 180 206.4 (169 848–190 650.5) | 461.4 (434.9–488.2) | 0.17 (0.12 to 0.22) | 1 095 456.1 (852 014.7–1 377 661.7) | 2754.1 (2132.6–3472.7) | −0.29 (−0.36 to 0.22) |
| Central Europe | 115 806.4 (108 220.5–124 704.8) | 224.3 (209.7–241.5) | −0.28 (−0.42 to 0.13) | 370 369.5 (314 160.5–432 383.1) | 549.3 (457.9–649.8) | −4.06 (−4.21 to 3.91) |
| Eastern Europe | 336 351 (291 026.9–391 204.6) | 310.1 (268.4–360.7) | −0.34 (−0.38 to 0.3) | 836 030.3 (716 986.9–958 746.2) | 630.7 (539.7–726.8) | −3.67 (−3.88 to 3.45) |
| Western Europe | 365 373.7 (355 654.1–375 560.1) | 176.5 (171.8–181.4) | −0.02 (−0.04–0) | 1 145 158.4 (992 872.6–1 311 287.5) | 426.4 (371.6–483.7) | −1.83 (−1.96 to 1.7) |
| Andean Latin America | 238 243.1 (215 056.2–259 154.6) | 378.8 (341.9–412) | −0.48 (−0.58 to 0.38) | 1 091 231.9 (860 579.1–1 361 890.9) | 1724.2 (1358.4–2154.9) | −2.51 (−2.61 to 2.41) |
| Central Latin America | 785 713.5 (699 016.6–879 676.1) | 372.3 (331.3–416.7) | 0.42 (0.33 to 0.5) | 2 926 331.9 (2 360 704.4–3 546 600.3) | 1340.3 (1073.9–1634.2) | −2.75 (−2.81 to 2.69) |
| Southern Latin America | 78 603.6 (74 432.4–83 455.8) | 169.5 (160.4–179.9) | 0 (−0.04 to 0.03) | 462 939.5 (378 389.2–566 820.7) | 934.3 (758–1151.5) | −2.95 (−3.03 to 2.87) |
| Tropical Latin America | 579 792.4 (523 428.1–652 126.9) | 375.1 (338.7–421.8) | 0.18 (0.14 to 0.23) | 3 292 307.5 (2 722 392–3 928 836.7) | 2013 (1649.4–2431.3) | −2.58 (−2.7 to 2.46) |
| North Africa and Middle East | 2 102 529.7 (2 016 483.5–2 198 106.4) | 361.3 (346.5–377.7) | 0.16 (0.13 to 0.18) | 11 489 912.5 (9 809 947–13 589 112.4) | 1950.8 (1664.1–2310) | −3.02 (−3.08 to 2.96) |
| High-income North America | 536 707.3 (520 574.5–555 108) | 266 (258.1–275.1) | 0.22 (0.06 to 0.37) | 1 725 713.1 (1 552 834.7–1 910 605) | 731.8 (663.9–803.4) | −0.89 (−0.99 to 0.78) |
| Oceania | 51 008.5 (47 734.4–54 574.9) | 259.1 (242.4–277.2) | −0.19 (−0.25 to 0.14) | 468 500.8 (346 400.8–621 679.8) | 2414.7 (1792.7–3194.9) | −0.27 (−0.36 to 0.18) |
| Central Sub-Saharan Africa | 726 892.4 (672 375.2–791 568) | 341.5 (315.8–371.8) | 0.02 (−0.04 to 0.08) | 6 488 410.7 (5 461 238.2–7 787 853) | 3098.5 (2612.9–3713.8) | −1.17 (−1.27 to 1.06) |
| Eastern Sub-Saharan Africa | 2 846 008.8 (2 601 338.8–3 150 784.9) | 422.1 (385.7–467.2) | −0.3 (−0.39 to 0.22) | 25 303 562.7 (20 467 578.7–31 448 404.6) | 3826 (3118.4–4737.9) | −1.04 (−1.12 to 0.96) |
| Southern Sub-Saharan Africa | 318 918.8 (296 475.4–348 024.6) | 400.7 (372.5–437.2) | 0.02 (−0.01 to 0.05) | 2 828 758.7 (2 280 606.2–3 564 928.6) | 3539.9 (2849.5–4464.4) | −0.19 (−0.46 to 0.08) |
| Western Sub-Saharan Africa | 3 387 570.3 (3 156 763–3 678 125.4) | 432.4 (402.9–469.5) | −0.23 (−0.25 to 0.21) | 35 857 700.2 (30 100 630.3–43 307 004.3) | 4640.7 (3904.2–5599.4) | −0.71 (−0.75 to 0.66) |
| Categories of causes | ||||||
| Neonatal preterm birth | 15 217 461.3 (15 111 175.9–15 319 933.8) | 235 (233.3–236.5) | −0.19 (−0.26 to 0.11) | 68 616 784.2 (58 968 980.1–80 042 972.6) | 1037.7 (891.7–1212.3) | −1.82 (−1.9 to 1.74) |
| Neonatal encephalopathy due to birth asphyxia and trauma | 13 786 98.9 (963 701.4–2 024 055.5) | 21.3 (14.9–31.3) | 0.07 (−0.01 to 0.15) | 53 356 613.1 (45 101 595.8–62 832 901.8) | 817 (691.1–964.4) | −1.03 (−1.23 to 0.83) |
| Neonatal sepsis and other neonatal infections | 6310 067 (4506 664.5–8 497 411.2) | 97.4 (69.6–131.2) | 0.46 (0.43 to 0.48) | 24 558 388.9 (20 811 235–29 489 763) | 368.3 (311.7–443.1) | −0.04 (−0.17 to 0.08) |
| Haemolytic disease and other neonatal jaundice | 626 004.7 (468 641.9–826 281.3) | 9.7 (7.2–12.8) | 0.13 (0.03 to 0.23) | 5 423 416.3 (4 620 169.1–6 392 084.5) | 82.1 (69.9–96.9) | −2.53 (−2.71 to 2.34) |
| Other neonatal disorders | – | – | – | 33 931 187.7 (28 467 048.5–40 943 840.9) | 523.3 (439–631.5) | −1.06 (−1.24 to 0.88) |
| . | 2019 . | 1990–2019 . | 2019 . | 1990–2019 . | ||
|---|---|---|---|---|---|---|
| . | Incident cases no. . | ASIR per 100 000 no. (95% UI) . | EAPC no. (95% CI) . | DALYs cases no. . | ASR-DALYs per 100 000 no. (95% UI) . | EAPC no. (95%CI) . |
| Overall | 23 532 231.9 (21 672 528.3–25 701 964.3) | 363.3 (334.6–396.8) | 0 (−0.06 to 0.06) | 185 886 390.1 (160 501 578.5–218 526 197.2) | 2828.3 (2441.6–3329.6) | −1.3 (−1.42 to 1.18) |
| Sex | ||||||
| Female | 10 878 088.4 (9 970 690.3–11 891 471.3) | 347.9 (318.8–380.3) | 0.05 (0 to 0.1) | 80 903 864.6 (70 493 249.1–93 894 238.7) | 2538.6 (2212.3–2954.3) | −1.38 (−1.48 to 1.27) |
| Male | 12 654 143.5 (11 671 263.4–13 791 272.5) | 377.8 (348.5–411.8) | −0.05 (−0.12 to 0.02) | 104 982 525.5 (89 992 179.3–124 058 674.9) | 3098.4 (2651.3–3663.6) | −1.24 (−1.38 to 1.1) |
| Age | ||||||
| <0–6 days | 4 272 672.2 (2 989 705.5–6 179 729.5) | 166 116.7 (116 236.4–240 261) | 0.49 (0.46 to 0.52) | 136 889 316.2 (116 450 062.3–162 669 807.7) | 5 322 103.3 (4 527 448–6 324 419.9) | −1.26 (−1.43 to 1.09) |
| 7–27 days | 1 652 243.5 (815 834.4–2 853 664.3) | 21 608.5 (10 669.7–37 321) | 0.58 (0.5 to 0.65) | 22 579 369.3 (19 087 688.7–26 853 350.5) | 295 299.5 (249 634.3–351 195.8) | −2.37 (−2.48 to 2.27) |
| 28–364 days | 0 | 0 | – | 7 857 828.2 (6 263 541.1–9 739 467.7) | 6453.2 (5143.9–7998.4) | −2.47 (−2.53 to 2.41) |
| 1–4 years | 0 | 0 | – | 2 942 759.6 (2 413 382.4–3 524 298.1) | 554.3 (454.6–663.9) | 0.63 (0.49 to 0.77) |
| 5–9 years | 0 | 0 | – | 1 953 414.4 (1 532 122.1–2 415 866.6) | 298.4 (234–369) | 2.52 (2.33 to 2.71) |
| 10–19 years | 0 | 0 | – | 3 588 557.3 (2 834 483.7–4 397 908) | 284.4 (224.7–348.6) | 2.76 (2.56 to 2.95) |
| 20–54 years | 0 | 0 | – | 8 573 707 (6 801 690.7–10 521 594.4) | 228.5 (181.3–280.4) | 2.7 (2.5 to 2.89) |
| 55+ years | 0 | 0 | – | 1 501 438 (1 177 534.6–1 888 579) | 54.8 (43–68.9) | 2.93 (2.6 to 3.26) |
| Socio-demographic index | ||||||
| High | 1 089 953.2 (1 054 989.2–1 127 074.9) | 219.5 (212.5–227) | 0.21 (0.11 to 0.31) | 3 455 360.4 (3 065 324.4–3 877 433.8) | 553.1 (498.2–613.1) | −1.78 (−1.85 to 1.71) |
| High-middle | 804 064.4 (555 269–1 087 955.6) | 297.9 (264.8–335.5) | 0.15 (0.13 to 0.18) | 8 524 076.6 (7 479 005.4–9 701 687.2) | 953.2 (835.9–1093.7) | −3.18 (−3.31 to 3.05) |
| Middle | 1 875 710.2 (1 290 221.3–2 558 776.4) | 328.5 (293.7–369.2) | 0 (−0.03 to 0.04) | 30 903 196.3 (26 745 267.2–35 818 934.6) | 1707.9 (1475.1–1987.3) | −2.25 (−2.42 to 2.07) |
| Low-middle | 1 591 860.7 (1 132 016.7–2 146 643.7) | 390.8 (361.4–424.6) | −0.31 (−0.37 to 0.25) | 64 958 149.6 (55 797 763.5–75 326 412.4) | 3804 (3265–4414.2) | −1.4 (−1.52 to 1.27) |
| Low | 1 510 719.9 (1 066 565.8–2 075 843.3) | 437.5 (409.1–471.4) | −0.17 (−0.22 to 0.12) | 77 939 747.9 (65 053 240.5–94 676 453.2) | 4386.5 (3671.1–5309.4) | −0.97 (−1.03 to 0.92) |
| GBD region | ||||||
| High-income Asia Pacific | 104 934.3 (101 365.4–108 619.4) | 158.4 (153.1–164) | 0.37 (0.29 to 0.44) | 320 692.9 (269 911–371 914.4) | 284.6 (248.8–322) | −2.28 (−2.43 to 2.14) |
| Central Asia | 223 779.7 (207 893.9–240 250.1) | 247.2 (229.7–265.3) | −0.36 (−0.41 to 0.31) | 1 522 378 (1 308 498.9–1 811 432.9) | 1665.1 (1430.7–1980.6) | −1.55 (−1.94 to 1.15) |
| East Asia | 2 136 197.7 (1 771 248.4–2 569 015) | 287.9 (238.8–345.9) | 0.38 (0.29 to 0.48) | 7 271 957.5 (6 376 403.8–8 313 229.2) | 786.8 (693.8–892.1) | −4.07 (−4.41 to 3.73) |
| South Asia | 66 292 44.7 (6 153 256.4–7 174 365.7) | 413.5 (383.7–447.4) | −0.27 (−0.32 to 0.22) | 71 241 073.2 (61 042 999–83 585 114.3) | 4395.1 (3765.2–5157.6) | −1.12 (−1.24–1) |
| Southeast Asia | 1 757 890.2 (1 535 711.2–2 004 844.2) | 336 (293.5–383.2) | −0.57 (−0.6 to 0.54) | 10 053 228.3 (8 349 665.4–12 031 297.8) | 1858.9 (1542.8–2234.4) | −2.2 (−2.28 to 2.12) |
| Australasia | 30 459.4 (28 790.5–32 063.1) | 172.4 (163–181.5) | 0.18 (0.09 to 0.26) | 94 676.6 (81 362.6–108 214.8) | 455.4 (391.4–519.4) | −1.66 (−1.78 to 1.54) |
| Caribbean | 180 206.4 (169 848–190 650.5) | 461.4 (434.9–488.2) | 0.17 (0.12 to 0.22) | 1 095 456.1 (852 014.7–1 377 661.7) | 2754.1 (2132.6–3472.7) | −0.29 (−0.36 to 0.22) |
| Central Europe | 115 806.4 (108 220.5–124 704.8) | 224.3 (209.7–241.5) | −0.28 (−0.42 to 0.13) | 370 369.5 (314 160.5–432 383.1) | 549.3 (457.9–649.8) | −4.06 (−4.21 to 3.91) |
| Eastern Europe | 336 351 (291 026.9–391 204.6) | 310.1 (268.4–360.7) | −0.34 (−0.38 to 0.3) | 836 030.3 (716 986.9–958 746.2) | 630.7 (539.7–726.8) | −3.67 (−3.88 to 3.45) |
| Western Europe | 365 373.7 (355 654.1–375 560.1) | 176.5 (171.8–181.4) | −0.02 (−0.04–0) | 1 145 158.4 (992 872.6–1 311 287.5) | 426.4 (371.6–483.7) | −1.83 (−1.96 to 1.7) |
| Andean Latin America | 238 243.1 (215 056.2–259 154.6) | 378.8 (341.9–412) | −0.48 (−0.58 to 0.38) | 1 091 231.9 (860 579.1–1 361 890.9) | 1724.2 (1358.4–2154.9) | −2.51 (−2.61 to 2.41) |
| Central Latin America | 785 713.5 (699 016.6–879 676.1) | 372.3 (331.3–416.7) | 0.42 (0.33 to 0.5) | 2 926 331.9 (2 360 704.4–3 546 600.3) | 1340.3 (1073.9–1634.2) | −2.75 (−2.81 to 2.69) |
| Southern Latin America | 78 603.6 (74 432.4–83 455.8) | 169.5 (160.4–179.9) | 0 (−0.04 to 0.03) | 462 939.5 (378 389.2–566 820.7) | 934.3 (758–1151.5) | −2.95 (−3.03 to 2.87) |
| Tropical Latin America | 579 792.4 (523 428.1–652 126.9) | 375.1 (338.7–421.8) | 0.18 (0.14 to 0.23) | 3 292 307.5 (2 722 392–3 928 836.7) | 2013 (1649.4–2431.3) | −2.58 (−2.7 to 2.46) |
| North Africa and Middle East | 2 102 529.7 (2 016 483.5–2 198 106.4) | 361.3 (346.5–377.7) | 0.16 (0.13 to 0.18) | 11 489 912.5 (9 809 947–13 589 112.4) | 1950.8 (1664.1–2310) | −3.02 (−3.08 to 2.96) |
| High-income North America | 536 707.3 (520 574.5–555 108) | 266 (258.1–275.1) | 0.22 (0.06 to 0.37) | 1 725 713.1 (1 552 834.7–1 910 605) | 731.8 (663.9–803.4) | −0.89 (−0.99 to 0.78) |
| Oceania | 51 008.5 (47 734.4–54 574.9) | 259.1 (242.4–277.2) | −0.19 (−0.25 to 0.14) | 468 500.8 (346 400.8–621 679.8) | 2414.7 (1792.7–3194.9) | −0.27 (−0.36 to 0.18) |
| Central Sub-Saharan Africa | 726 892.4 (672 375.2–791 568) | 341.5 (315.8–371.8) | 0.02 (−0.04 to 0.08) | 6 488 410.7 (5 461 238.2–7 787 853) | 3098.5 (2612.9–3713.8) | −1.17 (−1.27 to 1.06) |
| Eastern Sub-Saharan Africa | 2 846 008.8 (2 601 338.8–3 150 784.9) | 422.1 (385.7–467.2) | −0.3 (−0.39 to 0.22) | 25 303 562.7 (20 467 578.7–31 448 404.6) | 3826 (3118.4–4737.9) | −1.04 (−1.12 to 0.96) |
| Southern Sub-Saharan Africa | 318 918.8 (296 475.4–348 024.6) | 400.7 (372.5–437.2) | 0.02 (−0.01 to 0.05) | 2 828 758.7 (2 280 606.2–3 564 928.6) | 3539.9 (2849.5–4464.4) | −0.19 (−0.46 to 0.08) |
| Western Sub-Saharan Africa | 3 387 570.3 (3 156 763–3 678 125.4) | 432.4 (402.9–469.5) | −0.23 (−0.25 to 0.21) | 35 857 700.2 (30 100 630.3–43 307 004.3) | 4640.7 (3904.2–5599.4) | −0.71 (−0.75 to 0.66) |
| Categories of causes | ||||||
| Neonatal preterm birth | 15 217 461.3 (15 111 175.9–15 319 933.8) | 235 (233.3–236.5) | −0.19 (−0.26 to 0.11) | 68 616 784.2 (58 968 980.1–80 042 972.6) | 1037.7 (891.7–1212.3) | −1.82 (−1.9 to 1.74) |
| Neonatal encephalopathy due to birth asphyxia and trauma | 13 786 98.9 (963 701.4–2 024 055.5) | 21.3 (14.9–31.3) | 0.07 (−0.01 to 0.15) | 53 356 613.1 (45 101 595.8–62 832 901.8) | 817 (691.1–964.4) | −1.03 (−1.23 to 0.83) |
| Neonatal sepsis and other neonatal infections | 6310 067 (4506 664.5–8 497 411.2) | 97.4 (69.6–131.2) | 0.46 (0.43 to 0.48) | 24 558 388.9 (20 811 235–29 489 763) | 368.3 (311.7–443.1) | −0.04 (−0.17 to 0.08) |
| Haemolytic disease and other neonatal jaundice | 626 004.7 (468 641.9–826 281.3) | 9.7 (7.2–12.8) | 0.13 (0.03 to 0.23) | 5 423 416.3 (4 620 169.1–6 392 084.5) | 82.1 (69.9–96.9) | −2.53 (−2.71 to 2.34) |
| Other neonatal disorders | – | – | – | 33 931 187.7 (28 467 048.5–40 943 840.9) | 523.3 (439–631.5) | −1.06 (−1.24 to 0.88) |
ASIR, age-standardized incidence rate; DALYs, disability-adjusted life-years; ASR, age-standardized rate; EAPC, estimated annual percentage change; UI, uncertainty interval; CI, confidence interval.
The number and ASR of incident and DALYs for neonatal disorders in 2019, and changing trends from 1990 to 2019
| . | 2019 . | 1990–2019 . | 2019 . | 1990–2019 . | ||
|---|---|---|---|---|---|---|
| . | Incident cases no. . | ASIR per 100 000 no. (95% UI) . | EAPC no. (95% CI) . | DALYs cases no. . | ASR-DALYs per 100 000 no. (95% UI) . | EAPC no. (95%CI) . |
| Overall | 23 532 231.9 (21 672 528.3–25 701 964.3) | 363.3 (334.6–396.8) | 0 (−0.06 to 0.06) | 185 886 390.1 (160 501 578.5–218 526 197.2) | 2828.3 (2441.6–3329.6) | −1.3 (−1.42 to 1.18) |
| Sex | ||||||
| Female | 10 878 088.4 (9 970 690.3–11 891 471.3) | 347.9 (318.8–380.3) | 0.05 (0 to 0.1) | 80 903 864.6 (70 493 249.1–93 894 238.7) | 2538.6 (2212.3–2954.3) | −1.38 (−1.48 to 1.27) |
| Male | 12 654 143.5 (11 671 263.4–13 791 272.5) | 377.8 (348.5–411.8) | −0.05 (−0.12 to 0.02) | 104 982 525.5 (89 992 179.3–124 058 674.9) | 3098.4 (2651.3–3663.6) | −1.24 (−1.38 to 1.1) |
| Age | ||||||
| <0–6 days | 4 272 672.2 (2 989 705.5–6 179 729.5) | 166 116.7 (116 236.4–240 261) | 0.49 (0.46 to 0.52) | 136 889 316.2 (116 450 062.3–162 669 807.7) | 5 322 103.3 (4 527 448–6 324 419.9) | −1.26 (−1.43 to 1.09) |
| 7–27 days | 1 652 243.5 (815 834.4–2 853 664.3) | 21 608.5 (10 669.7–37 321) | 0.58 (0.5 to 0.65) | 22 579 369.3 (19 087 688.7–26 853 350.5) | 295 299.5 (249 634.3–351 195.8) | −2.37 (−2.48 to 2.27) |
| 28–364 days | 0 | 0 | – | 7 857 828.2 (6 263 541.1–9 739 467.7) | 6453.2 (5143.9–7998.4) | −2.47 (−2.53 to 2.41) |
| 1–4 years | 0 | 0 | – | 2 942 759.6 (2 413 382.4–3 524 298.1) | 554.3 (454.6–663.9) | 0.63 (0.49 to 0.77) |
| 5–9 years | 0 | 0 | – | 1 953 414.4 (1 532 122.1–2 415 866.6) | 298.4 (234–369) | 2.52 (2.33 to 2.71) |
| 10–19 years | 0 | 0 | – | 3 588 557.3 (2 834 483.7–4 397 908) | 284.4 (224.7–348.6) | 2.76 (2.56 to 2.95) |
| 20–54 years | 0 | 0 | – | 8 573 707 (6 801 690.7–10 521 594.4) | 228.5 (181.3–280.4) | 2.7 (2.5 to 2.89) |
| 55+ years | 0 | 0 | – | 1 501 438 (1 177 534.6–1 888 579) | 54.8 (43–68.9) | 2.93 (2.6 to 3.26) |
| Socio-demographic index | ||||||
| High | 1 089 953.2 (1 054 989.2–1 127 074.9) | 219.5 (212.5–227) | 0.21 (0.11 to 0.31) | 3 455 360.4 (3 065 324.4–3 877 433.8) | 553.1 (498.2–613.1) | −1.78 (−1.85 to 1.71) |
| High-middle | 804 064.4 (555 269–1 087 955.6) | 297.9 (264.8–335.5) | 0.15 (0.13 to 0.18) | 8 524 076.6 (7 479 005.4–9 701 687.2) | 953.2 (835.9–1093.7) | −3.18 (−3.31 to 3.05) |
| Middle | 1 875 710.2 (1 290 221.3–2 558 776.4) | 328.5 (293.7–369.2) | 0 (−0.03 to 0.04) | 30 903 196.3 (26 745 267.2–35 818 934.6) | 1707.9 (1475.1–1987.3) | −2.25 (−2.42 to 2.07) |
| Low-middle | 1 591 860.7 (1 132 016.7–2 146 643.7) | 390.8 (361.4–424.6) | −0.31 (−0.37 to 0.25) | 64 958 149.6 (55 797 763.5–75 326 412.4) | 3804 (3265–4414.2) | −1.4 (−1.52 to 1.27) |
| Low | 1 510 719.9 (1 066 565.8–2 075 843.3) | 437.5 (409.1–471.4) | −0.17 (−0.22 to 0.12) | 77 939 747.9 (65 053 240.5–94 676 453.2) | 4386.5 (3671.1–5309.4) | −0.97 (−1.03 to 0.92) |
| GBD region | ||||||
| High-income Asia Pacific | 104 934.3 (101 365.4–108 619.4) | 158.4 (153.1–164) | 0.37 (0.29 to 0.44) | 320 692.9 (269 911–371 914.4) | 284.6 (248.8–322) | −2.28 (−2.43 to 2.14) |
| Central Asia | 223 779.7 (207 893.9–240 250.1) | 247.2 (229.7–265.3) | −0.36 (−0.41 to 0.31) | 1 522 378 (1 308 498.9–1 811 432.9) | 1665.1 (1430.7–1980.6) | −1.55 (−1.94 to 1.15) |
| East Asia | 2 136 197.7 (1 771 248.4–2 569 015) | 287.9 (238.8–345.9) | 0.38 (0.29 to 0.48) | 7 271 957.5 (6 376 403.8–8 313 229.2) | 786.8 (693.8–892.1) | −4.07 (−4.41 to 3.73) |
| South Asia | 66 292 44.7 (6 153 256.4–7 174 365.7) | 413.5 (383.7–447.4) | −0.27 (−0.32 to 0.22) | 71 241 073.2 (61 042 999–83 585 114.3) | 4395.1 (3765.2–5157.6) | −1.12 (−1.24–1) |
| Southeast Asia | 1 757 890.2 (1 535 711.2–2 004 844.2) | 336 (293.5–383.2) | −0.57 (−0.6 to 0.54) | 10 053 228.3 (8 349 665.4–12 031 297.8) | 1858.9 (1542.8–2234.4) | −2.2 (−2.28 to 2.12) |
| Australasia | 30 459.4 (28 790.5–32 063.1) | 172.4 (163–181.5) | 0.18 (0.09 to 0.26) | 94 676.6 (81 362.6–108 214.8) | 455.4 (391.4–519.4) | −1.66 (−1.78 to 1.54) |
| Caribbean | 180 206.4 (169 848–190 650.5) | 461.4 (434.9–488.2) | 0.17 (0.12 to 0.22) | 1 095 456.1 (852 014.7–1 377 661.7) | 2754.1 (2132.6–3472.7) | −0.29 (−0.36 to 0.22) |
| Central Europe | 115 806.4 (108 220.5–124 704.8) | 224.3 (209.7–241.5) | −0.28 (−0.42 to 0.13) | 370 369.5 (314 160.5–432 383.1) | 549.3 (457.9–649.8) | −4.06 (−4.21 to 3.91) |
| Eastern Europe | 336 351 (291 026.9–391 204.6) | 310.1 (268.4–360.7) | −0.34 (−0.38 to 0.3) | 836 030.3 (716 986.9–958 746.2) | 630.7 (539.7–726.8) | −3.67 (−3.88 to 3.45) |
| Western Europe | 365 373.7 (355 654.1–375 560.1) | 176.5 (171.8–181.4) | −0.02 (−0.04–0) | 1 145 158.4 (992 872.6–1 311 287.5) | 426.4 (371.6–483.7) | −1.83 (−1.96 to 1.7) |
| Andean Latin America | 238 243.1 (215 056.2–259 154.6) | 378.8 (341.9–412) | −0.48 (−0.58 to 0.38) | 1 091 231.9 (860 579.1–1 361 890.9) | 1724.2 (1358.4–2154.9) | −2.51 (−2.61 to 2.41) |
| Central Latin America | 785 713.5 (699 016.6–879 676.1) | 372.3 (331.3–416.7) | 0.42 (0.33 to 0.5) | 2 926 331.9 (2 360 704.4–3 546 600.3) | 1340.3 (1073.9–1634.2) | −2.75 (−2.81 to 2.69) |
| Southern Latin America | 78 603.6 (74 432.4–83 455.8) | 169.5 (160.4–179.9) | 0 (−0.04 to 0.03) | 462 939.5 (378 389.2–566 820.7) | 934.3 (758–1151.5) | −2.95 (−3.03 to 2.87) |
| Tropical Latin America | 579 792.4 (523 428.1–652 126.9) | 375.1 (338.7–421.8) | 0.18 (0.14 to 0.23) | 3 292 307.5 (2 722 392–3 928 836.7) | 2013 (1649.4–2431.3) | −2.58 (−2.7 to 2.46) |
| North Africa and Middle East | 2 102 529.7 (2 016 483.5–2 198 106.4) | 361.3 (346.5–377.7) | 0.16 (0.13 to 0.18) | 11 489 912.5 (9 809 947–13 589 112.4) | 1950.8 (1664.1–2310) | −3.02 (−3.08 to 2.96) |
| High-income North America | 536 707.3 (520 574.5–555 108) | 266 (258.1–275.1) | 0.22 (0.06 to 0.37) | 1 725 713.1 (1 552 834.7–1 910 605) | 731.8 (663.9–803.4) | −0.89 (−0.99 to 0.78) |
| Oceania | 51 008.5 (47 734.4–54 574.9) | 259.1 (242.4–277.2) | −0.19 (−0.25 to 0.14) | 468 500.8 (346 400.8–621 679.8) | 2414.7 (1792.7–3194.9) | −0.27 (−0.36 to 0.18) |
| Central Sub-Saharan Africa | 726 892.4 (672 375.2–791 568) | 341.5 (315.8–371.8) | 0.02 (−0.04 to 0.08) | 6 488 410.7 (5 461 238.2–7 787 853) | 3098.5 (2612.9–3713.8) | −1.17 (−1.27 to 1.06) |
| Eastern Sub-Saharan Africa | 2 846 008.8 (2 601 338.8–3 150 784.9) | 422.1 (385.7–467.2) | −0.3 (−0.39 to 0.22) | 25 303 562.7 (20 467 578.7–31 448 404.6) | 3826 (3118.4–4737.9) | −1.04 (−1.12 to 0.96) |
| Southern Sub-Saharan Africa | 318 918.8 (296 475.4–348 024.6) | 400.7 (372.5–437.2) | 0.02 (−0.01 to 0.05) | 2 828 758.7 (2 280 606.2–3 564 928.6) | 3539.9 (2849.5–4464.4) | −0.19 (−0.46 to 0.08) |
| Western Sub-Saharan Africa | 3 387 570.3 (3 156 763–3 678 125.4) | 432.4 (402.9–469.5) | −0.23 (−0.25 to 0.21) | 35 857 700.2 (30 100 630.3–43 307 004.3) | 4640.7 (3904.2–5599.4) | −0.71 (−0.75 to 0.66) |
| Categories of causes | ||||||
| Neonatal preterm birth | 15 217 461.3 (15 111 175.9–15 319 933.8) | 235 (233.3–236.5) | −0.19 (−0.26 to 0.11) | 68 616 784.2 (58 968 980.1–80 042 972.6) | 1037.7 (891.7–1212.3) | −1.82 (−1.9 to 1.74) |
| Neonatal encephalopathy due to birth asphyxia and trauma | 13 786 98.9 (963 701.4–2 024 055.5) | 21.3 (14.9–31.3) | 0.07 (−0.01 to 0.15) | 53 356 613.1 (45 101 595.8–62 832 901.8) | 817 (691.1–964.4) | −1.03 (−1.23 to 0.83) |
| Neonatal sepsis and other neonatal infections | 6310 067 (4506 664.5–8 497 411.2) | 97.4 (69.6–131.2) | 0.46 (0.43 to 0.48) | 24 558 388.9 (20 811 235–29 489 763) | 368.3 (311.7–443.1) | −0.04 (−0.17 to 0.08) |
| Haemolytic disease and other neonatal jaundice | 626 004.7 (468 641.9–826 281.3) | 9.7 (7.2–12.8) | 0.13 (0.03 to 0.23) | 5 423 416.3 (4 620 169.1–6 392 084.5) | 82.1 (69.9–96.9) | −2.53 (−2.71 to 2.34) |
| Other neonatal disorders | – | – | – | 33 931 187.7 (28 467 048.5–40 943 840.9) | 523.3 (439–631.5) | −1.06 (−1.24 to 0.88) |
| . | 2019 . | 1990–2019 . | 2019 . | 1990–2019 . | ||
|---|---|---|---|---|---|---|
| . | Incident cases no. . | ASIR per 100 000 no. (95% UI) . | EAPC no. (95% CI) . | DALYs cases no. . | ASR-DALYs per 100 000 no. (95% UI) . | EAPC no. (95%CI) . |
| Overall | 23 532 231.9 (21 672 528.3–25 701 964.3) | 363.3 (334.6–396.8) | 0 (−0.06 to 0.06) | 185 886 390.1 (160 501 578.5–218 526 197.2) | 2828.3 (2441.6–3329.6) | −1.3 (−1.42 to 1.18) |
| Sex | ||||||
| Female | 10 878 088.4 (9 970 690.3–11 891 471.3) | 347.9 (318.8–380.3) | 0.05 (0 to 0.1) | 80 903 864.6 (70 493 249.1–93 894 238.7) | 2538.6 (2212.3–2954.3) | −1.38 (−1.48 to 1.27) |
| Male | 12 654 143.5 (11 671 263.4–13 791 272.5) | 377.8 (348.5–411.8) | −0.05 (−0.12 to 0.02) | 104 982 525.5 (89 992 179.3–124 058 674.9) | 3098.4 (2651.3–3663.6) | −1.24 (−1.38 to 1.1) |
| Age | ||||||
| <0–6 days | 4 272 672.2 (2 989 705.5–6 179 729.5) | 166 116.7 (116 236.4–240 261) | 0.49 (0.46 to 0.52) | 136 889 316.2 (116 450 062.3–162 669 807.7) | 5 322 103.3 (4 527 448–6 324 419.9) | −1.26 (−1.43 to 1.09) |
| 7–27 days | 1 652 243.5 (815 834.4–2 853 664.3) | 21 608.5 (10 669.7–37 321) | 0.58 (0.5 to 0.65) | 22 579 369.3 (19 087 688.7–26 853 350.5) | 295 299.5 (249 634.3–351 195.8) | −2.37 (−2.48 to 2.27) |
| 28–364 days | 0 | 0 | – | 7 857 828.2 (6 263 541.1–9 739 467.7) | 6453.2 (5143.9–7998.4) | −2.47 (−2.53 to 2.41) |
| 1–4 years | 0 | 0 | – | 2 942 759.6 (2 413 382.4–3 524 298.1) | 554.3 (454.6–663.9) | 0.63 (0.49 to 0.77) |
| 5–9 years | 0 | 0 | – | 1 953 414.4 (1 532 122.1–2 415 866.6) | 298.4 (234–369) | 2.52 (2.33 to 2.71) |
| 10–19 years | 0 | 0 | – | 3 588 557.3 (2 834 483.7–4 397 908) | 284.4 (224.7–348.6) | 2.76 (2.56 to 2.95) |
| 20–54 years | 0 | 0 | – | 8 573 707 (6 801 690.7–10 521 594.4) | 228.5 (181.3–280.4) | 2.7 (2.5 to 2.89) |
| 55+ years | 0 | 0 | – | 1 501 438 (1 177 534.6–1 888 579) | 54.8 (43–68.9) | 2.93 (2.6 to 3.26) |
| Socio-demographic index | ||||||
| High | 1 089 953.2 (1 054 989.2–1 127 074.9) | 219.5 (212.5–227) | 0.21 (0.11 to 0.31) | 3 455 360.4 (3 065 324.4–3 877 433.8) | 553.1 (498.2–613.1) | −1.78 (−1.85 to 1.71) |
| High-middle | 804 064.4 (555 269–1 087 955.6) | 297.9 (264.8–335.5) | 0.15 (0.13 to 0.18) | 8 524 076.6 (7 479 005.4–9 701 687.2) | 953.2 (835.9–1093.7) | −3.18 (−3.31 to 3.05) |
| Middle | 1 875 710.2 (1 290 221.3–2 558 776.4) | 328.5 (293.7–369.2) | 0 (−0.03 to 0.04) | 30 903 196.3 (26 745 267.2–35 818 934.6) | 1707.9 (1475.1–1987.3) | −2.25 (−2.42 to 2.07) |
| Low-middle | 1 591 860.7 (1 132 016.7–2 146 643.7) | 390.8 (361.4–424.6) | −0.31 (−0.37 to 0.25) | 64 958 149.6 (55 797 763.5–75 326 412.4) | 3804 (3265–4414.2) | −1.4 (−1.52 to 1.27) |
| Low | 1 510 719.9 (1 066 565.8–2 075 843.3) | 437.5 (409.1–471.4) | −0.17 (−0.22 to 0.12) | 77 939 747.9 (65 053 240.5–94 676 453.2) | 4386.5 (3671.1–5309.4) | −0.97 (−1.03 to 0.92) |
| GBD region | ||||||
| High-income Asia Pacific | 104 934.3 (101 365.4–108 619.4) | 158.4 (153.1–164) | 0.37 (0.29 to 0.44) | 320 692.9 (269 911–371 914.4) | 284.6 (248.8–322) | −2.28 (−2.43 to 2.14) |
| Central Asia | 223 779.7 (207 893.9–240 250.1) | 247.2 (229.7–265.3) | −0.36 (−0.41 to 0.31) | 1 522 378 (1 308 498.9–1 811 432.9) | 1665.1 (1430.7–1980.6) | −1.55 (−1.94 to 1.15) |
| East Asia | 2 136 197.7 (1 771 248.4–2 569 015) | 287.9 (238.8–345.9) | 0.38 (0.29 to 0.48) | 7 271 957.5 (6 376 403.8–8 313 229.2) | 786.8 (693.8–892.1) | −4.07 (−4.41 to 3.73) |
| South Asia | 66 292 44.7 (6 153 256.4–7 174 365.7) | 413.5 (383.7–447.4) | −0.27 (−0.32 to 0.22) | 71 241 073.2 (61 042 999–83 585 114.3) | 4395.1 (3765.2–5157.6) | −1.12 (−1.24–1) |
| Southeast Asia | 1 757 890.2 (1 535 711.2–2 004 844.2) | 336 (293.5–383.2) | −0.57 (−0.6 to 0.54) | 10 053 228.3 (8 349 665.4–12 031 297.8) | 1858.9 (1542.8–2234.4) | −2.2 (−2.28 to 2.12) |
| Australasia | 30 459.4 (28 790.5–32 063.1) | 172.4 (163–181.5) | 0.18 (0.09 to 0.26) | 94 676.6 (81 362.6–108 214.8) | 455.4 (391.4–519.4) | −1.66 (−1.78 to 1.54) |
| Caribbean | 180 206.4 (169 848–190 650.5) | 461.4 (434.9–488.2) | 0.17 (0.12 to 0.22) | 1 095 456.1 (852 014.7–1 377 661.7) | 2754.1 (2132.6–3472.7) | −0.29 (−0.36 to 0.22) |
| Central Europe | 115 806.4 (108 220.5–124 704.8) | 224.3 (209.7–241.5) | −0.28 (−0.42 to 0.13) | 370 369.5 (314 160.5–432 383.1) | 549.3 (457.9–649.8) | −4.06 (−4.21 to 3.91) |
| Eastern Europe | 336 351 (291 026.9–391 204.6) | 310.1 (268.4–360.7) | −0.34 (−0.38 to 0.3) | 836 030.3 (716 986.9–958 746.2) | 630.7 (539.7–726.8) | −3.67 (−3.88 to 3.45) |
| Western Europe | 365 373.7 (355 654.1–375 560.1) | 176.5 (171.8–181.4) | −0.02 (−0.04–0) | 1 145 158.4 (992 872.6–1 311 287.5) | 426.4 (371.6–483.7) | −1.83 (−1.96 to 1.7) |
| Andean Latin America | 238 243.1 (215 056.2–259 154.6) | 378.8 (341.9–412) | −0.48 (−0.58 to 0.38) | 1 091 231.9 (860 579.1–1 361 890.9) | 1724.2 (1358.4–2154.9) | −2.51 (−2.61 to 2.41) |
| Central Latin America | 785 713.5 (699 016.6–879 676.1) | 372.3 (331.3–416.7) | 0.42 (0.33 to 0.5) | 2 926 331.9 (2 360 704.4–3 546 600.3) | 1340.3 (1073.9–1634.2) | −2.75 (−2.81 to 2.69) |
| Southern Latin America | 78 603.6 (74 432.4–83 455.8) | 169.5 (160.4–179.9) | 0 (−0.04 to 0.03) | 462 939.5 (378 389.2–566 820.7) | 934.3 (758–1151.5) | −2.95 (−3.03 to 2.87) |
| Tropical Latin America | 579 792.4 (523 428.1–652 126.9) | 375.1 (338.7–421.8) | 0.18 (0.14 to 0.23) | 3 292 307.5 (2 722 392–3 928 836.7) | 2013 (1649.4–2431.3) | −2.58 (−2.7 to 2.46) |
| North Africa and Middle East | 2 102 529.7 (2 016 483.5–2 198 106.4) | 361.3 (346.5–377.7) | 0.16 (0.13 to 0.18) | 11 489 912.5 (9 809 947–13 589 112.4) | 1950.8 (1664.1–2310) | −3.02 (−3.08 to 2.96) |
| High-income North America | 536 707.3 (520 574.5–555 108) | 266 (258.1–275.1) | 0.22 (0.06 to 0.37) | 1 725 713.1 (1 552 834.7–1 910 605) | 731.8 (663.9–803.4) | −0.89 (−0.99 to 0.78) |
| Oceania | 51 008.5 (47 734.4–54 574.9) | 259.1 (242.4–277.2) | −0.19 (−0.25 to 0.14) | 468 500.8 (346 400.8–621 679.8) | 2414.7 (1792.7–3194.9) | −0.27 (−0.36 to 0.18) |
| Central Sub-Saharan Africa | 726 892.4 (672 375.2–791 568) | 341.5 (315.8–371.8) | 0.02 (−0.04 to 0.08) | 6 488 410.7 (5 461 238.2–7 787 853) | 3098.5 (2612.9–3713.8) | −1.17 (−1.27 to 1.06) |
| Eastern Sub-Saharan Africa | 2 846 008.8 (2 601 338.8–3 150 784.9) | 422.1 (385.7–467.2) | −0.3 (−0.39 to 0.22) | 25 303 562.7 (20 467 578.7–31 448 404.6) | 3826 (3118.4–4737.9) | −1.04 (−1.12 to 0.96) |
| Southern Sub-Saharan Africa | 318 918.8 (296 475.4–348 024.6) | 400.7 (372.5–437.2) | 0.02 (−0.01 to 0.05) | 2 828 758.7 (2 280 606.2–3 564 928.6) | 3539.9 (2849.5–4464.4) | −0.19 (−0.46 to 0.08) |
| Western Sub-Saharan Africa | 3 387 570.3 (3 156 763–3 678 125.4) | 432.4 (402.9–469.5) | −0.23 (−0.25 to 0.21) | 35 857 700.2 (30 100 630.3–43 307 004.3) | 4640.7 (3904.2–5599.4) | −0.71 (−0.75 to 0.66) |
| Categories of causes | ||||||
| Neonatal preterm birth | 15 217 461.3 (15 111 175.9–15 319 933.8) | 235 (233.3–236.5) | −0.19 (−0.26 to 0.11) | 68 616 784.2 (58 968 980.1–80 042 972.6) | 1037.7 (891.7–1212.3) | −1.82 (−1.9 to 1.74) |
| Neonatal encephalopathy due to birth asphyxia and trauma | 13 786 98.9 (963 701.4–2 024 055.5) | 21.3 (14.9–31.3) | 0.07 (−0.01 to 0.15) | 53 356 613.1 (45 101 595.8–62 832 901.8) | 817 (691.1–964.4) | −1.03 (−1.23 to 0.83) |
| Neonatal sepsis and other neonatal infections | 6310 067 (4506 664.5–8 497 411.2) | 97.4 (69.6–131.2) | 0.46 (0.43 to 0.48) | 24 558 388.9 (20 811 235–29 489 763) | 368.3 (311.7–443.1) | −0.04 (−0.17 to 0.08) |
| Haemolytic disease and other neonatal jaundice | 626 004.7 (468 641.9–826 281.3) | 9.7 (7.2–12.8) | 0.13 (0.03 to 0.23) | 5 423 416.3 (4 620 169.1–6 392 084.5) | 82.1 (69.9–96.9) | −2.53 (−2.71 to 2.34) |
| Other neonatal disorders | – | – | – | 33 931 187.7 (28 467 048.5–40 943 840.9) | 523.3 (439–631.5) | −1.06 (−1.24 to 0.88) |
ASIR, age-standardized incidence rate; DALYs, disability-adjusted life-years; ASR, age-standardized rate; EAPC, estimated annual percentage change; UI, uncertainty interval; CI, confidence interval.
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