Relative Reduction in ILTFU Between Baseline and Intervention Periods by Place of Diagnosis for Subdistricts by Intervention Type
| . | Oct–Dec 2018 . | Jan 2019–Dec 2020 . | Relative Reduction ILTFU (95% CI), % . | P Value 1-Sided T Testa . | |||
|---|---|---|---|---|---|---|---|
| Newly Diagnosed PWTB, No. . | ILTFU, No. (%) (95% CI, %) . | Newly Diagnosed PWTB, No. . | ILTFU, No. (%) (95% CI, %) . | ||||
| Subdistricts implementing the hospital-recording intervention (no intervention in surrounding facilities) | |||||||
| Umdoni (KwaZulu-Natal) | GJ Crookes Hosp | 65 | 23 (35.4) (23.8–47) | 345 | 73 (21.2) (16.8–25.5) | 40.2 (12–59.4) | .0141 |
| Surrounding PHC facilities | 66 | 10 (15.2) (6.5–23.8) | 445 | 62 (13.9) (10.7–17.2) | 8 (−70.2 to 50.3) | .3989 | |
| Region D (Gauteng) | CH Baragwanath Hosp | 169 | 94 (55.6) (48.1–63.1) | 1167 | 746 (63.9) (61.2–66.7) | −14.9 (−32.4 to 0.2) | .9784 |
| Surrounding PHC facilities | 544 | 114 (21.0) (17.5–24.4) | 2932 | 555 (18.9) (17.5–20.3) | 9.7 (−7.5 to 2.1) | .1420 | |
| Tygerberg (Western Cape) | Tygerberg Hospital | 173 | 74 (42.8) (35.4–50.1) | 1132 | 509 (45) (42.1–47.9) | −5.1 (−26.4 to 12.5) | .7053 |
| Surrounding PHC facilities | 588 | 111 (18.9) (15.7–22) | 3963 | 564 (14.2) (13.1–15.3) | 24.6 (9.4–37.3) | .0015 | |
| Subdistricts implementing the alert-and-response patient management intervention | |||||||
| Ray Nkonyeni (KwaZulu-Natal) | Gamalakhe CHC | 59 | 7 (11.9) (3.6–20.1) | 410 | 47 (11.5) (8.4–14.5) | 3.4 (−103.7 to 54.2) | .4648 |
| Surrounding PHC facilities | 137 | 41 (29.9) (22.3–37.6) | 799 | 103 (12.9) (10.6–15.2) | 56.9 (41.1–68.5) | <.0001 | |
| Region E (Gauteng) | Edenvale Hospital | 59 | 43 (72.9) (61.5–84.2) | 409 | 259 (63.3) (58.7–68) | 13.1 (−3.2 to 26.9) | .0668 |
| Surrounding PHC facilities | 149 | 41 (27.5) (20.3–34.7) | 891 | 212 (23.8) (21.0–26.6) | 13.5 (−15.1 to 35) | .1728 | |
| Khayelitsha (Western Cape) | Khayelitsha Hospital | 79 | 22 (27.8) (18.0–37.7) | 808 | 251 (31.1) (27.9–34.3) | −11.6 (−61.4 to 22.9) | .7261 |
| Surrounding PHC facilities | 483 | 89 (18.4) (15.0–21.9) | 3456 | 303 (8.8) (7.8–9.7) | 52.4 (40.9–61.7) | <.0001 | |
| . | Oct–Dec 2018 . | Jan 2019–Dec 2020 . | Relative Reduction ILTFU (95% CI), % . | P Value 1-Sided T Testa . | |||
|---|---|---|---|---|---|---|---|
| Newly Diagnosed PWTB, No. . | ILTFU, No. (%) (95% CI, %) . | Newly Diagnosed PWTB, No. . | ILTFU, No. (%) (95% CI, %) . | ||||
| Subdistricts implementing the hospital-recording intervention (no intervention in surrounding facilities) | |||||||
| Umdoni (KwaZulu-Natal) | GJ Crookes Hosp | 65 | 23 (35.4) (23.8–47) | 345 | 73 (21.2) (16.8–25.5) | 40.2 (12–59.4) | .0141 |
| Surrounding PHC facilities | 66 | 10 (15.2) (6.5–23.8) | 445 | 62 (13.9) (10.7–17.2) | 8 (−70.2 to 50.3) | .3989 | |
| Region D (Gauteng) | CH Baragwanath Hosp | 169 | 94 (55.6) (48.1–63.1) | 1167 | 746 (63.9) (61.2–66.7) | −14.9 (−32.4 to 0.2) | .9784 |
| Surrounding PHC facilities | 544 | 114 (21.0) (17.5–24.4) | 2932 | 555 (18.9) (17.5–20.3) | 9.7 (−7.5 to 2.1) | .1420 | |
| Tygerberg (Western Cape) | Tygerberg Hospital | 173 | 74 (42.8) (35.4–50.1) | 1132 | 509 (45) (42.1–47.9) | −5.1 (−26.4 to 12.5) | .7053 |
| Surrounding PHC facilities | 588 | 111 (18.9) (15.7–22) | 3963 | 564 (14.2) (13.1–15.3) | 24.6 (9.4–37.3) | .0015 | |
| Subdistricts implementing the alert-and-response patient management intervention | |||||||
| Ray Nkonyeni (KwaZulu-Natal) | Gamalakhe CHC | 59 | 7 (11.9) (3.6–20.1) | 410 | 47 (11.5) (8.4–14.5) | 3.4 (−103.7 to 54.2) | .4648 |
| Surrounding PHC facilities | 137 | 41 (29.9) (22.3–37.6) | 799 | 103 (12.9) (10.6–15.2) | 56.9 (41.1–68.5) | <.0001 | |
| Region E (Gauteng) | Edenvale Hospital | 59 | 43 (72.9) (61.5–84.2) | 409 | 259 (63.3) (58.7–68) | 13.1 (−3.2 to 26.9) | .0668 |
| Surrounding PHC facilities | 149 | 41 (27.5) (20.3–34.7) | 891 | 212 (23.8) (21.0–26.6) | 13.5 (−15.1 to 35) | .1728 | |
| Khayelitsha (Western Cape) | Khayelitsha Hospital | 79 | 22 (27.8) (18.0–37.7) | 808 | 251 (31.1) (27.9–34.3) | −11.6 (−61.4 to 22.9) | .7261 |
| Surrounding PHC facilities | 483 | 89 (18.4) (15.0–21.9) | 3456 | 303 (8.8) (7.8–9.7) | 52.4 (40.9–61.7) | <.0001 | |
aOne-sided t test: based on the null hypothesis that the percent ILTFU was not reduced from baseline to intervention.
Abbreviations: ILTFU, initial loss to follow-up; PHC, primary health care; PWTB, person with tuberculosis.
Relative Reduction in ILTFU Between Baseline and Intervention Periods by Place of Diagnosis for Subdistricts by Intervention Type
| . | Oct–Dec 2018 . | Jan 2019–Dec 2020 . | Relative Reduction ILTFU (95% CI), % . | P Value 1-Sided T Testa . | |||
|---|---|---|---|---|---|---|---|
| Newly Diagnosed PWTB, No. . | ILTFU, No. (%) (95% CI, %) . | Newly Diagnosed PWTB, No. . | ILTFU, No. (%) (95% CI, %) . | ||||
| Subdistricts implementing the hospital-recording intervention (no intervention in surrounding facilities) | |||||||
| Umdoni (KwaZulu-Natal) | GJ Crookes Hosp | 65 | 23 (35.4) (23.8–47) | 345 | 73 (21.2) (16.8–25.5) | 40.2 (12–59.4) | .0141 |
| Surrounding PHC facilities | 66 | 10 (15.2) (6.5–23.8) | 445 | 62 (13.9) (10.7–17.2) | 8 (−70.2 to 50.3) | .3989 | |
| Region D (Gauteng) | CH Baragwanath Hosp | 169 | 94 (55.6) (48.1–63.1) | 1167 | 746 (63.9) (61.2–66.7) | −14.9 (−32.4 to 0.2) | .9784 |
| Surrounding PHC facilities | 544 | 114 (21.0) (17.5–24.4) | 2932 | 555 (18.9) (17.5–20.3) | 9.7 (−7.5 to 2.1) | .1420 | |
| Tygerberg (Western Cape) | Tygerberg Hospital | 173 | 74 (42.8) (35.4–50.1) | 1132 | 509 (45) (42.1–47.9) | −5.1 (−26.4 to 12.5) | .7053 |
| Surrounding PHC facilities | 588 | 111 (18.9) (15.7–22) | 3963 | 564 (14.2) (13.1–15.3) | 24.6 (9.4–37.3) | .0015 | |
| Subdistricts implementing the alert-and-response patient management intervention | |||||||
| Ray Nkonyeni (KwaZulu-Natal) | Gamalakhe CHC | 59 | 7 (11.9) (3.6–20.1) | 410 | 47 (11.5) (8.4–14.5) | 3.4 (−103.7 to 54.2) | .4648 |
| Surrounding PHC facilities | 137 | 41 (29.9) (22.3–37.6) | 799 | 103 (12.9) (10.6–15.2) | 56.9 (41.1–68.5) | <.0001 | |
| Region E (Gauteng) | Edenvale Hospital | 59 | 43 (72.9) (61.5–84.2) | 409 | 259 (63.3) (58.7–68) | 13.1 (−3.2 to 26.9) | .0668 |
| Surrounding PHC facilities | 149 | 41 (27.5) (20.3–34.7) | 891 | 212 (23.8) (21.0–26.6) | 13.5 (−15.1 to 35) | .1728 | |
| Khayelitsha (Western Cape) | Khayelitsha Hospital | 79 | 22 (27.8) (18.0–37.7) | 808 | 251 (31.1) (27.9–34.3) | −11.6 (−61.4 to 22.9) | .7261 |
| Surrounding PHC facilities | 483 | 89 (18.4) (15.0–21.9) | 3456 | 303 (8.8) (7.8–9.7) | 52.4 (40.9–61.7) | <.0001 | |
| . | Oct–Dec 2018 . | Jan 2019–Dec 2020 . | Relative Reduction ILTFU (95% CI), % . | P Value 1-Sided T Testa . | |||
|---|---|---|---|---|---|---|---|
| Newly Diagnosed PWTB, No. . | ILTFU, No. (%) (95% CI, %) . | Newly Diagnosed PWTB, No. . | ILTFU, No. (%) (95% CI, %) . | ||||
| Subdistricts implementing the hospital-recording intervention (no intervention in surrounding facilities) | |||||||
| Umdoni (KwaZulu-Natal) | GJ Crookes Hosp | 65 | 23 (35.4) (23.8–47) | 345 | 73 (21.2) (16.8–25.5) | 40.2 (12–59.4) | .0141 |
| Surrounding PHC facilities | 66 | 10 (15.2) (6.5–23.8) | 445 | 62 (13.9) (10.7–17.2) | 8 (−70.2 to 50.3) | .3989 | |
| Region D (Gauteng) | CH Baragwanath Hosp | 169 | 94 (55.6) (48.1–63.1) | 1167 | 746 (63.9) (61.2–66.7) | −14.9 (−32.4 to 0.2) | .9784 |
| Surrounding PHC facilities | 544 | 114 (21.0) (17.5–24.4) | 2932 | 555 (18.9) (17.5–20.3) | 9.7 (−7.5 to 2.1) | .1420 | |
| Tygerberg (Western Cape) | Tygerberg Hospital | 173 | 74 (42.8) (35.4–50.1) | 1132 | 509 (45) (42.1–47.9) | −5.1 (−26.4 to 12.5) | .7053 |
| Surrounding PHC facilities | 588 | 111 (18.9) (15.7–22) | 3963 | 564 (14.2) (13.1–15.3) | 24.6 (9.4–37.3) | .0015 | |
| Subdistricts implementing the alert-and-response patient management intervention | |||||||
| Ray Nkonyeni (KwaZulu-Natal) | Gamalakhe CHC | 59 | 7 (11.9) (3.6–20.1) | 410 | 47 (11.5) (8.4–14.5) | 3.4 (−103.7 to 54.2) | .4648 |
| Surrounding PHC facilities | 137 | 41 (29.9) (22.3–37.6) | 799 | 103 (12.9) (10.6–15.2) | 56.9 (41.1–68.5) | <.0001 | |
| Region E (Gauteng) | Edenvale Hospital | 59 | 43 (72.9) (61.5–84.2) | 409 | 259 (63.3) (58.7–68) | 13.1 (−3.2 to 26.9) | .0668 |
| Surrounding PHC facilities | 149 | 41 (27.5) (20.3–34.7) | 891 | 212 (23.8) (21.0–26.6) | 13.5 (−15.1 to 35) | .1728 | |
| Khayelitsha (Western Cape) | Khayelitsha Hospital | 79 | 22 (27.8) (18.0–37.7) | 808 | 251 (31.1) (27.9–34.3) | −11.6 (−61.4 to 22.9) | .7261 |
| Surrounding PHC facilities | 483 | 89 (18.4) (15.0–21.9) | 3456 | 303 (8.8) (7.8–9.7) | 52.4 (40.9–61.7) | <.0001 | |
aOne-sided t test: based on the null hypothesis that the percent ILTFU was not reduced from baseline to intervention.
Abbreviations: ILTFU, initial loss to follow-up; PHC, primary health care; PWTB, person with tuberculosis.
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