Table 1: Open in new tab Patient...

	Albumin ≥3 g/dl (N = 173)	Albumin <3 g/dl (N = 56)	P-value
Preoperative recipient characteristics
Male sex	129 (74.6)	38 (67.9)	0.387
Age (years)	55.1 ± 10.8	55.3 ± 11	0.904
BMI (kg/m²)	25.8 ± 4.5	25.4 ± 4.7	0.614
Smoker	45 (26.2)	12 (21.4)	0.594
Diabetes	32 (18.7)	18 (32.1)	0.042
Arterial hypertension	98 (57)	32 (57.1)	>0.999
Pulmonary hypertension	14 (8.1)	7 (12.5)	0.424
Prior cardiothoracic surgery	101 (58.4)	44 (78.6)	0.007
LVAD	78 (45.1)	37 (66.1)	0.009
ICM	73 (42.4)	25 (44.6)	0.877
DCM	81 (47.1)	28 (50)	0.759
ARVC	7 (4.1)	1 (1.8)	0.683
RCM	0 (0)	1 (1.8)	0.246
HCM	3 (1.7)	1 (1.8)	>0.999
Myocarditis	2 (1.2)	0 (0)	>0.999
Preoperative dialysis	10 (5.8)	2 (3.7)	0.736
IMPACT score	8.1 ± 4.7	9.4 ± 4.1	0.096
Albumin (g/dl)	3.9 ± 0.7	3.7 ± 0.7	0.185
MELD score	14.3 ± 7.6	13.7 ± 6.5	0.652
Donor characteristics
Male sex	98 (56.6)	28 (50)	0.441
Age (years)	43.1 ± 12.2	44.3 ± 12.4	0.526
BMI (kg/m²)	26.1 ± 4.9	26.0 ± 3.7	0.945
Cardiopulmonary resuscitation	53 (30.6)	15 (26.8)	0.618
Intraoperative characteristics (min)
Duration of surgery	401 ± 95	490 ± 148	<0.001
Duration of CPB	240 ± 57	294 ± 94	<0.001
Total ischaemia time	212 ± 48	220 ± 51	0.330
PRBC (l)	2.9 ± 2.4	4.9 ± 3.2	<0.001
Platelets (l)	1.0 ± 0.8	1.5 ± 1.1	0.001
FFP (l)	1.5 ± 1.6	1.9 ± 2.3	0.218
Postoperative laboratory values
Creatinine (mg/dl)	1.5 ± 0.8	1.3 ± 0.5	0.230
Bilirubin (mg/dl)	2.6 ± 1.9	2.5 ± 1.3	0.576
INR	1.2 ± 1.9	1.3 ± 2.2	0.280
Albumin (g/dl)	3.5 ± 0.4	2.4 ± 0.4	<0.001
Postoperative characteristics
ECMO	33 (19.2)	28 (50)	<0.001
Renal replacement therapy	90 (57.7)	35 (62.5)	0.635
MELD score	14.6 ± 5.3	14.3 ± 5.1	0.711
Albumin substitution within first 24 h	47 (28.7)	29 (54.7)	0.001
Days in ICU	24 ± 25	25 ± 26	0.677
Duration of mechanical ventilation (hours)	110 ± 167	223 ± 216	0.001
30-day mortality	6 (3.5)	12 (21.4)	<0.001
1-year mortality	18 (10.4)	22 (39.3)	<0.001

Albumin ≥3 g/dl (N = 173)

Albumin <3 g/dl (N = 56)

P-value

Preoperative recipient characteristics

Male sex

129 (74.6)

38 (67.9)

0.387

Age (years)

55.1 ± 10.8

55.3 ± 11

0.904

BMI (kg/m²)

25.8 ± 4.5

25.4 ± 4.7

0.614

Smoker

45 (26.2)

12 (21.4)

0.594

Diabetes

32 (18.7)

18 (32.1)

0.042

Arterial hypertension

98 (57)

32 (57.1)

>0.999

Pulmonary hypertension

14 (8.1)

7 (12.5)

0.424

Prior cardiothoracic surgery

101 (58.4)

44 (78.6)

0.007

LVAD

78 (45.1)

37 (66.1)

0.009

ICM

73 (42.4)

25 (44.6)

0.877

DCM

81 (47.1)

28 (50)

0.759

ARVC

7 (4.1)

1 (1.8)

0.683

RCM

0 (0)

1 (1.8)

0.246

HCM

3 (1.7)

1 (1.8)

>0.999

Myocarditis

2 (1.2)

0 (0)

>0.999

Preoperative dialysis

10 (5.8)

2 (3.7)

0.736

IMPACT score

8.1 ± 4.7

9.4 ± 4.1

0.096

Albumin (g/dl)

3.9 ± 0.7

3.7 ± 0.7

0.185

MELD score

14.3 ± 7.6

13.7 ± 6.5

0.652

Donor characteristics

Male sex

98 (56.6)

28 (50)

0.441

Age (years)

43.1 ± 12.2

44.3 ± 12.4

0.526

BMI (kg/m²)

26.1 ± 4.9

26.0 ± 3.7

0.945

Cardiopulmonary resuscitation

53 (30.6)

15 (26.8)

0.618

Intraoperative characteristics (min)

Duration of surgery

401 ± 95

490 ± 148

<0.001

Duration of CPB

240 ± 57

294 ± 94

<0.001

Total ischaemia time

212 ± 48

220 ± 51

0.330

PRBC (l)

2.9 ± 2.4

4.9 ± 3.2

<0.001

Platelets (l)

1.0 ± 0.8

1.5 ± 1.1

0.001

FFP (l)

1.5 ± 1.6

1.9 ± 2.3

0.218

Postoperative laboratory values

Creatinine (mg/dl)

1.5 ± 0.8

1.3 ± 0.5

0.230

Bilirubin (mg/dl)

2.6 ± 1.9

2.5 ± 1.3

0.576

INR

1.2 ± 1.9

1.3 ± 2.2

0.280

Albumin (g/dl)

3.5 ± 0.4

2.4 ± 0.4

<0.001

Postoperative characteristics

ECMO

33 (19.2)

28 (50)

<0.001

Renal replacement therapy

90 (57.7)

35 (62.5)

0.635

MELD score

14.6 ± 5.3

14.3 ± 5.1

0.711

Albumin substitution within first 24 h

47 (28.7)

29 (54.7)

0.001

Days in ICU

24 ± 25

25 ± 26

0.677

Duration of mechanical ventilation (hours)

110 ± 167

223 ± 216

0.001

30-day mortality

6 (3.5)

12 (21.4)

<0.001

1-year mortality

18 (10.4)

22 (39.3)

<0.001

	Albumin ≥3 g/dl (N = 173)	Albumin <3 g/dl (N = 56)	P-value
Preoperative recipient characteristics
Male sex	129 (74.6)	38 (67.9)	0.387
Age (years)	55.1 ± 10.8	55.3 ± 11	0.904
BMI (kg/m²)	25.8 ± 4.5	25.4 ± 4.7	0.614
Smoker	45 (26.2)	12 (21.4)	0.594
Diabetes	32 (18.7)	18 (32.1)	0.042
Arterial hypertension	98 (57)	32 (57.1)	>0.999
Pulmonary hypertension	14 (8.1)	7 (12.5)	0.424
Prior cardiothoracic surgery	101 (58.4)	44 (78.6)	0.007
LVAD	78 (45.1)	37 (66.1)	0.009
ICM	73 (42.4)	25 (44.6)	0.877
DCM	81 (47.1)	28 (50)	0.759
ARVC	7 (4.1)	1 (1.8)	0.683
RCM	0 (0)	1 (1.8)	0.246
HCM	3 (1.7)	1 (1.8)	>0.999
Myocarditis	2 (1.2)	0 (0)	>0.999
Preoperative dialysis	10 (5.8)	2 (3.7)	0.736
IMPACT score	8.1 ± 4.7	9.4 ± 4.1	0.096
Albumin (g/dl)	3.9 ± 0.7	3.7 ± 0.7	0.185
MELD score	14.3 ± 7.6	13.7 ± 6.5	0.652
Donor characteristics
Male sex	98 (56.6)	28 (50)	0.441
Age (years)	43.1 ± 12.2	44.3 ± 12.4	0.526
BMI (kg/m²)	26.1 ± 4.9	26.0 ± 3.7	0.945
Cardiopulmonary resuscitation	53 (30.6)	15 (26.8)	0.618
Intraoperative characteristics (min)
Duration of surgery	401 ± 95	490 ± 148	<0.001
Duration of CPB	240 ± 57	294 ± 94	<0.001
Total ischaemia time	212 ± 48	220 ± 51	0.330
PRBC (l)	2.9 ± 2.4	4.9 ± 3.2	<0.001
Platelets (l)	1.0 ± 0.8	1.5 ± 1.1	0.001
FFP (l)	1.5 ± 1.6	1.9 ± 2.3	0.218
Postoperative laboratory values
Creatinine (mg/dl)	1.5 ± 0.8	1.3 ± 0.5	0.230
Bilirubin (mg/dl)	2.6 ± 1.9	2.5 ± 1.3	0.576
INR	1.2 ± 1.9	1.3 ± 2.2	0.280
Albumin (g/dl)	3.5 ± 0.4	2.4 ± 0.4	<0.001
Postoperative characteristics
ECMO	33 (19.2)	28 (50)	<0.001
Renal replacement therapy	90 (57.7)	35 (62.5)	0.635
MELD score	14.6 ± 5.3	14.3 ± 5.1	0.711
Albumin substitution within first 24 h	47 (28.7)	29 (54.7)	0.001
Days in ICU	24 ± 25	25 ± 26	0.677
Duration of mechanical ventilation (hours)	110 ± 167	223 ± 216	0.001
30-day mortality	6 (3.5)	12 (21.4)	<0.001
1-year mortality	18 (10.4)	22 (39.3)	<0.001

Table 1:

Open in new tab

Patient characteristics by postoperative albumin levels

	Albumin ≥3 g/dl (N = 173)	Albumin <3 g/dl (N = 56)	P-value
Preoperative recipient characteristics
Male sex	129 (74.6)	38 (67.9)	0.387
Age (years)	55.1 ± 10.8	55.3 ± 11	0.904
BMI (kg/m²)	25.8 ± 4.5	25.4 ± 4.7	0.614
Smoker	45 (26.2)	12 (21.4)	0.594
Diabetes	32 (18.7)	18 (32.1)	0.042
Arterial hypertension	98 (57)	32 (57.1)	>0.999
Pulmonary hypertension	14 (8.1)	7 (12.5)	0.424
Prior cardiothoracic surgery	101 (58.4)	44 (78.6)	0.007
LVAD	78 (45.1)	37 (66.1)	0.009
ICM	73 (42.4)	25 (44.6)	0.877
DCM	81 (47.1)	28 (50)	0.759
ARVC	7 (4.1)	1 (1.8)	0.683
RCM	0 (0)	1 (1.8)	0.246
HCM	3 (1.7)	1 (1.8)	>0.999
Myocarditis	2 (1.2)	0 (0)	>0.999
Preoperative dialysis	10 (5.8)	2 (3.7)	0.736
IMPACT score	8.1 ± 4.7	9.4 ± 4.1	0.096
Albumin (g/dl)	3.9 ± 0.7	3.7 ± 0.7	0.185
MELD score	14.3 ± 7.6	13.7 ± 6.5	0.652
Donor characteristics
Male sex	98 (56.6)	28 (50)	0.441
Age (years)	43.1 ± 12.2	44.3 ± 12.4	0.526
BMI (kg/m²)	26.1 ± 4.9	26.0 ± 3.7	0.945
Cardiopulmonary resuscitation	53 (30.6)	15 (26.8)	0.618
Intraoperative characteristics (min)
Duration of surgery	401 ± 95	490 ± 148	<0.001
Duration of CPB	240 ± 57	294 ± 94	<0.001
Total ischaemia time	212 ± 48	220 ± 51	0.330
PRBC (l)	2.9 ± 2.4	4.9 ± 3.2	<0.001
Platelets (l)	1.0 ± 0.8	1.5 ± 1.1	0.001
FFP (l)	1.5 ± 1.6	1.9 ± 2.3	0.218
Postoperative laboratory values
Creatinine (mg/dl)	1.5 ± 0.8	1.3 ± 0.5	0.230
Bilirubin (mg/dl)	2.6 ± 1.9	2.5 ± 1.3	0.576
INR	1.2 ± 1.9	1.3 ± 2.2	0.280
Albumin (g/dl)	3.5 ± 0.4	2.4 ± 0.4	<0.001
Postoperative characteristics
ECMO	33 (19.2)	28 (50)	<0.001
Renal replacement therapy	90 (57.7)	35 (62.5)	0.635
MELD score	14.6 ± 5.3	14.3 ± 5.1	0.711
Albumin substitution within first 24 h	47 (28.7)	29 (54.7)	0.001
Days in ICU	24 ± 25	25 ± 26	0.677
Duration of mechanical ventilation (hours)	110 ± 167	223 ± 216	0.001
30-day mortality	6 (3.5)	12 (21.4)	<0.001
1-year mortality	18 (10.4)	22 (39.3)	<0.001

	Albumin ≥3 g/dl (N = 173)	Albumin <3 g/dl (N = 56)	P-value
Preoperative recipient characteristics
Male sex	129 (74.6)	38 (67.9)	0.387
Age (years)	55.1 ± 10.8	55.3 ± 11	0.904
BMI (kg/m²)	25.8 ± 4.5	25.4 ± 4.7	0.614
Smoker	45 (26.2)	12 (21.4)	0.594
Diabetes	32 (18.7)	18 (32.1)	0.042
Arterial hypertension	98 (57)	32 (57.1)	>0.999
Pulmonary hypertension	14 (8.1)	7 (12.5)	0.424
Prior cardiothoracic surgery	101 (58.4)	44 (78.6)	0.007
LVAD	78 (45.1)	37 (66.1)	0.009
ICM	73 (42.4)	25 (44.6)	0.877
DCM	81 (47.1)	28 (50)	0.759
ARVC	7 (4.1)	1 (1.8)	0.683
RCM	0 (0)	1 (1.8)	0.246
HCM	3 (1.7)	1 (1.8)	>0.999
Myocarditis	2 (1.2)	0 (0)	>0.999
Preoperative dialysis	10 (5.8)	2 (3.7)	0.736
IMPACT score	8.1 ± 4.7	9.4 ± 4.1	0.096
Albumin (g/dl)	3.9 ± 0.7	3.7 ± 0.7	0.185
MELD score	14.3 ± 7.6	13.7 ± 6.5	0.652
Donor characteristics
Male sex	98 (56.6)	28 (50)	0.441
Age (years)	43.1 ± 12.2	44.3 ± 12.4	0.526
BMI (kg/m²)	26.1 ± 4.9	26.0 ± 3.7	0.945
Cardiopulmonary resuscitation	53 (30.6)	15 (26.8)	0.618
Intraoperative characteristics (min)
Duration of surgery	401 ± 95	490 ± 148	<0.001
Duration of CPB	240 ± 57	294 ± 94	<0.001
Total ischaemia time	212 ± 48	220 ± 51	0.330
PRBC (l)	2.9 ± 2.4	4.9 ± 3.2	<0.001
Platelets (l)	1.0 ± 0.8	1.5 ± 1.1	0.001
FFP (l)	1.5 ± 1.6	1.9 ± 2.3	0.218
Postoperative laboratory values
Creatinine (mg/dl)	1.5 ± 0.8	1.3 ± 0.5	0.230
Bilirubin (mg/dl)	2.6 ± 1.9	2.5 ± 1.3	0.576
INR	1.2 ± 1.9	1.3 ± 2.2	0.280
Albumin (g/dl)	3.5 ± 0.4	2.4 ± 0.4	<0.001
Postoperative characteristics
ECMO	33 (19.2)	28 (50)	<0.001
Renal replacement therapy	90 (57.7)	35 (62.5)	0.635
MELD score	14.6 ± 5.3	14.3 ± 5.1	0.711
Albumin substitution within first 24 h	47 (28.7)	29 (54.7)	0.001
Days in ICU	24 ± 25	25 ± 26	0.677
Duration of mechanical ventilation (hours)	110 ± 167	223 ± 216	0.001
30-day mortality	6 (3.5)	12 (21.4)	<0.001
1-year mortality	18 (10.4)	22 (39.3)	<0.001

ARVC, arrhythmogenic right ventricular cardiomyopathy; BMI, body mass index; CPB, cardiopulmonary bypass; DCM, dilative cardiomyopathy; ECMO; extracorporeal membrane oxygenation; FFP, fresh frozen plasma; HCM, hypertrophic cardiomyopathy; ICM, ischaemic cardiomyopathy; IMPACT, risk index for mortality prediction after cardiac transplantation; ICU, intensive care unit; INR, international normalized ratio; LVAD, left ventricular assist device; MELD, model for end-stage liver disease; PRBC, packed red blood cells; RCM, restrictive cardiomyopathy [11].

Significant results are marked in bold.

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