Estimated Overall Risk of Recurrence and Relative Risk by HIV Status Under 5 Strategies for Handling Post-treatment Deaths
| . | Adjusted for Missing FU . | Not Adjusted for Missing FU . | ||
|---|---|---|---|---|
| Strategy . | Overall Risk per 1000a . | Relative Riska,b . | Overall Risk Per 1000a . | Relative Riska,b . |
| Observed recurrence | 7.4 (3.3–12.8) | 1.2 (0.0–5.1) | 8.0 (3.3–13.6) | 1.3 (0.0–5.1) |
| Hypothetical recurrence | 7.6 (3.3–13.0) | 1.2 (0.0–4.8) | 8.1 (3.3–13.8) | 1.3 (0.0–4.8) |
| Observed composite/any | 25.5 (15.3–38.1) | 0.6 (0.1–1.7) | 21.7 (14.2–29.9) | 0.8 (0.1–2.1) |
| Observed composite/probable | 11.7 (6.4–18.2) | 0.7 (0.0–2.7) | 12.9 (7.1–19.6) | 0.7 (0.0–2.6) |
| Observed composite/explicit | 8.6 (4.1–14.4) | 1.0 (0.0–3.8) | 9.6 (4.8–15.8) | 1.0 (0.0–3.7) |
| . | Adjusted for Missing FU . | Not Adjusted for Missing FU . | ||
|---|---|---|---|---|
| Strategy . | Overall Risk per 1000a . | Relative Riska,b . | Overall Risk Per 1000a . | Relative Riska,b . |
| Observed recurrence | 7.4 (3.3–12.8) | 1.2 (0.0–5.1) | 8.0 (3.3–13.6) | 1.3 (0.0–5.1) |
| Hypothetical recurrence | 7.6 (3.3–13.0) | 1.2 (0.0–4.8) | 8.1 (3.3–13.8) | 1.3 (0.0–4.8) |
| Observed composite/any | 25.5 (15.3–38.1) | 0.6 (0.1–1.7) | 21.7 (14.2–29.9) | 0.8 (0.1–2.1) |
| Observed composite/probable | 11.7 (6.4–18.2) | 0.7 (0.0–2.7) | 12.9 (7.1–19.6) | 0.7 (0.0–2.6) |
| Observed composite/explicit | 8.6 (4.1–14.4) | 1.0 (0.0–3.8) | 9.6 (4.8–15.8) | 1.0 (0.0–3.7) |
Abbreviations: FU, follow-up; HIV, human immunodeficiency virus.
a95% credible intervals are constructed as the 2.5th and 97.5th percentiles of the 1000 bootstrap sample estimates.
bRelative risk is comparing the risk of outcome among people with HIV (numerator) and this risk among people without HIV (denominator).
Estimated Overall Risk of Recurrence and Relative Risk by HIV Status Under 5 Strategies for Handling Post-treatment Deaths
| . | Adjusted for Missing FU . | Not Adjusted for Missing FU . | ||
|---|---|---|---|---|
| Strategy . | Overall Risk per 1000a . | Relative Riska,b . | Overall Risk Per 1000a . | Relative Riska,b . |
| Observed recurrence | 7.4 (3.3–12.8) | 1.2 (0.0–5.1) | 8.0 (3.3–13.6) | 1.3 (0.0–5.1) |
| Hypothetical recurrence | 7.6 (3.3–13.0) | 1.2 (0.0–4.8) | 8.1 (3.3–13.8) | 1.3 (0.0–4.8) |
| Observed composite/any | 25.5 (15.3–38.1) | 0.6 (0.1–1.7) | 21.7 (14.2–29.9) | 0.8 (0.1–2.1) |
| Observed composite/probable | 11.7 (6.4–18.2) | 0.7 (0.0–2.7) | 12.9 (7.1–19.6) | 0.7 (0.0–2.6) |
| Observed composite/explicit | 8.6 (4.1–14.4) | 1.0 (0.0–3.8) | 9.6 (4.8–15.8) | 1.0 (0.0–3.7) |
| . | Adjusted for Missing FU . | Not Adjusted for Missing FU . | ||
|---|---|---|---|---|
| Strategy . | Overall Risk per 1000a . | Relative Riska,b . | Overall Risk Per 1000a . | Relative Riska,b . |
| Observed recurrence | 7.4 (3.3–12.8) | 1.2 (0.0–5.1) | 8.0 (3.3–13.6) | 1.3 (0.0–5.1) |
| Hypothetical recurrence | 7.6 (3.3–13.0) | 1.2 (0.0–4.8) | 8.1 (3.3–13.8) | 1.3 (0.0–4.8) |
| Observed composite/any | 25.5 (15.3–38.1) | 0.6 (0.1–1.7) | 21.7 (14.2–29.9) | 0.8 (0.1–2.1) |
| Observed composite/probable | 11.7 (6.4–18.2) | 0.7 (0.0–2.7) | 12.9 (7.1–19.6) | 0.7 (0.0–2.6) |
| Observed composite/explicit | 8.6 (4.1–14.4) | 1.0 (0.0–3.8) | 9.6 (4.8–15.8) | 1.0 (0.0–3.7) |
Abbreviations: FU, follow-up; HIV, human immunodeficiency virus.
a95% credible intervals are constructed as the 2.5th and 97.5th percentiles of the 1000 bootstrap sample estimates.
bRelative risk is comparing the risk of outcome among people with HIV (numerator) and this risk among people without HIV (denominator).
This PDF is available to Subscribers Only
View Article Abstract & Purchase OptionsFor full access to this pdf, sign in to an existing account, or purchase an annual subscription.
