Table 3.

Odds Ratios Obtained With Unadjusted and Adjusted Logistic Regression Assessing the Relationship of Variables to In-Hospital Death

VariableUnadjusted Regression ModelAdjusted Regression Model
OR (95% CI)P ValueOR (95% CI)P Value
Age (in years)1.0 (1.0–1.0).041.01 (.99–1.04).3
Male sex0.89 (.55–1.4).630.57 (.33–1.00).05
Diabetes1.3 (.80–2.2).29
Liver disease1.5 (.82–2.7).19
Chronic kidney disease1.1 (.6–1.8).85
Cancer1.7 (1.0–2.7).05
Solid tumor0.89 (.47–1.7).720.91 (.40–2.08).83
Hematologic cancer2.5 (1.4–4.6)<.014.48 (2.13–9.41)<.001
Immunosuppression1.4 (.83–2.2).23
ANC <500/µL2.4 (1.2–4.9).02
Charlson comorbidity index1.1 (1.0–1.2).041.14 (.99–1.30).06
Infection source
 Abdominal0.8 (.47–1.3).39
 Urinary tract0.58 (.3–1.1).09
 Central catheter0.42 (.13–1.4).15
 Respiratory tract8.1 (3.9–16.9)<.0015.35 (2.23–12.79)<.001
 Unidentified0.92 (.52–1.7).79
Antibiotic resistant
 Ceftriaxone2.1 (1.2–3.5).01
 Cefepime3.8 (1.9–7.7)<.001
  Piperacillin-tazobactam2.9 (1.5–5.5).00
 Aminoglycoside1.9 (.93–3.9).08
 Fluoroquinolone1.4 (.76–2.4).29
 MDR1.7 (.94–3.1).08
Delay of ≥4 h to antibiotic treatment1.5 (.9–2.4).12
Incorrect 1st antibiotic3.8 (1.9–7.7)<.0015.22 (2.21–12.37)<.001
ID consultation0.83 (.51–1.3).44
Hospital-acquired infection2.8 (1.7–4.5)<.001
ICU admission4.72 (2.86–7.79)<.0015.06 (2.82–9.07)<.001
VariableUnadjusted Regression ModelAdjusted Regression Model
OR (95% CI)P ValueOR (95% CI)P Value
Age (in years)1.0 (1.0–1.0).041.01 (.99–1.04).3
Male sex0.89 (.55–1.4).630.57 (.33–1.00).05
Diabetes1.3 (.80–2.2).29
Liver disease1.5 (.82–2.7).19
Chronic kidney disease1.1 (.6–1.8).85
Cancer1.7 (1.0–2.7).05
Solid tumor0.89 (.47–1.7).720.91 (.40–2.08).83
Hematologic cancer2.5 (1.4–4.6)<.014.48 (2.13–9.41)<.001
Immunosuppression1.4 (.83–2.2).23
ANC <500/µL2.4 (1.2–4.9).02
Charlson comorbidity index1.1 (1.0–1.2).041.14 (.99–1.30).06
Infection source
 Abdominal0.8 (.47–1.3).39
 Urinary tract0.58 (.3–1.1).09
 Central catheter0.42 (.13–1.4).15
 Respiratory tract8.1 (3.9–16.9)<.0015.35 (2.23–12.79)<.001
 Unidentified0.92 (.52–1.7).79
Antibiotic resistant
 Ceftriaxone2.1 (1.2–3.5).01
 Cefepime3.8 (1.9–7.7)<.001
  Piperacillin-tazobactam2.9 (1.5–5.5).00
 Aminoglycoside1.9 (.93–3.9).08
 Fluoroquinolone1.4 (.76–2.4).29
 MDR1.7 (.94–3.1).08
Delay of ≥4 h to antibiotic treatment1.5 (.9–2.4).12
Incorrect 1st antibiotic3.8 (1.9–7.7)<.0015.22 (2.21–12.37)<.001
ID consultation0.83 (.51–1.3).44
Hospital-acquired infection2.8 (1.7–4.5)<.001
ICU admission4.72 (2.86–7.79)<.0015.06 (2.82–9.07)<.001

Abbreviations: ANC, absolute neutrophil count; CI, confidence interval; ICU, intensive care unit; ID, infectious diseases; MDR, multidrug resistance; OR, odds ratio.

Table 3.

Odds Ratios Obtained With Unadjusted and Adjusted Logistic Regression Assessing the Relationship of Variables to In-Hospital Death

VariableUnadjusted Regression ModelAdjusted Regression Model
OR (95% CI)P ValueOR (95% CI)P Value
Age (in years)1.0 (1.0–1.0).041.01 (.99–1.04).3
Male sex0.89 (.55–1.4).630.57 (.33–1.00).05
Diabetes1.3 (.80–2.2).29
Liver disease1.5 (.82–2.7).19
Chronic kidney disease1.1 (.6–1.8).85
Cancer1.7 (1.0–2.7).05
Solid tumor0.89 (.47–1.7).720.91 (.40–2.08).83
Hematologic cancer2.5 (1.4–4.6)<.014.48 (2.13–9.41)<.001
Immunosuppression1.4 (.83–2.2).23
ANC <500/µL2.4 (1.2–4.9).02
Charlson comorbidity index1.1 (1.0–1.2).041.14 (.99–1.30).06
Infection source
 Abdominal0.8 (.47–1.3).39
 Urinary tract0.58 (.3–1.1).09
 Central catheter0.42 (.13–1.4).15
 Respiratory tract8.1 (3.9–16.9)<.0015.35 (2.23–12.79)<.001
 Unidentified0.92 (.52–1.7).79
Antibiotic resistant
 Ceftriaxone2.1 (1.2–3.5).01
 Cefepime3.8 (1.9–7.7)<.001
  Piperacillin-tazobactam2.9 (1.5–5.5).00
 Aminoglycoside1.9 (.93–3.9).08
 Fluoroquinolone1.4 (.76–2.4).29
 MDR1.7 (.94–3.1).08
Delay of ≥4 h to antibiotic treatment1.5 (.9–2.4).12
Incorrect 1st antibiotic3.8 (1.9–7.7)<.0015.22 (2.21–12.37)<.001
ID consultation0.83 (.51–1.3).44
Hospital-acquired infection2.8 (1.7–4.5)<.001
ICU admission4.72 (2.86–7.79)<.0015.06 (2.82–9.07)<.001
VariableUnadjusted Regression ModelAdjusted Regression Model
OR (95% CI)P ValueOR (95% CI)P Value
Age (in years)1.0 (1.0–1.0).041.01 (.99–1.04).3
Male sex0.89 (.55–1.4).630.57 (.33–1.00).05
Diabetes1.3 (.80–2.2).29
Liver disease1.5 (.82–2.7).19
Chronic kidney disease1.1 (.6–1.8).85
Cancer1.7 (1.0–2.7).05
Solid tumor0.89 (.47–1.7).720.91 (.40–2.08).83
Hematologic cancer2.5 (1.4–4.6)<.014.48 (2.13–9.41)<.001
Immunosuppression1.4 (.83–2.2).23
ANC <500/µL2.4 (1.2–4.9).02
Charlson comorbidity index1.1 (1.0–1.2).041.14 (.99–1.30).06
Infection source
 Abdominal0.8 (.47–1.3).39
 Urinary tract0.58 (.3–1.1).09
 Central catheter0.42 (.13–1.4).15
 Respiratory tract8.1 (3.9–16.9)<.0015.35 (2.23–12.79)<.001
 Unidentified0.92 (.52–1.7).79
Antibiotic resistant
 Ceftriaxone2.1 (1.2–3.5).01
 Cefepime3.8 (1.9–7.7)<.001
  Piperacillin-tazobactam2.9 (1.5–5.5).00
 Aminoglycoside1.9 (.93–3.9).08
 Fluoroquinolone1.4 (.76–2.4).29
 MDR1.7 (.94–3.1).08
Delay of ≥4 h to antibiotic treatment1.5 (.9–2.4).12
Incorrect 1st antibiotic3.8 (1.9–7.7)<.0015.22 (2.21–12.37)<.001
ID consultation0.83 (.51–1.3).44
Hospital-acquired infection2.8 (1.7–4.5)<.001
ICU admission4.72 (2.86–7.79)<.0015.06 (2.82–9.07)<.001

Abbreviations: ANC, absolute neutrophil count; CI, confidence interval; ICU, intensive care unit; ID, infectious diseases; MDR, multidrug resistance; OR, odds ratio.

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