| Outcome . | Total cohort (N = 2519), n (%) . | Hb <100 g/l (n = 1254), n (%) . | Hb ≥100 g/l (n = 1265), n (%) . | P-value . | Time-averaged Hb <100 g/l (n = 529), n (%) . | Time-averaged Hb ≥100 g/l (n = 1318), n (%) . | P-value . |
|---|---|---|---|---|---|---|---|
| Death | 264 (4.56) | 143 (5.08) | 121 (4.07) | .070 | 55 (4.31) | 65 (1.86) | <.001 |
| Cardiovascular events | 181 (3.13) | 98 (3.48) | 83 (2.79) | .132 | 38 (2.98) | 46 (1.31) | <.001 |
| Infection | 22 (0.38) | 11 (0.39) | 11 (0.37) | .881 | 4 (0.31) | 7 (0.20) | .410 |
| Tumour | 14 (0.24) | 8 (0.28) | 6 (0.20) | .523 | 3 (0.24) | 3 (0.09) | .156 |
| Severe malnutrition | 12 (0.21) | 6 (0.21) | 6 (0.20) | .932 | 3 (0.24) | 2 (0.06) | .074 |
| Multi-organ failure | 7 (0.12) | 5 (0.18) | 2 (0.07) | .231 | 1 (0.08) | 1 (0.03) | .478 |
| Gastrointestinal haemorrhage | 5 (0.09) | 2 (0.07) | 3 (0.10) | .686 | 1 (0.08) | 1 (0.03) | .372 |
| Unknown or miscellaneous | 23 (0.40) | 13 (0.46) | 10 (0.34) | .443 | 5 (0.39) | 5 (0.14) | .071 |
| MACE | 218 (3.77) | 115 (4.08) | 103 (3.47) | .225 | 42 (3.29) | 52 (1.49) | <.001 |
| Stroke | 24 (0.41) | 13 (0.46) | 11 (0.37) | .597 | 4 (0.31) | 4 (0.11) | .127 |
| Unstable angina | 15 (0.26) | 8 (0.28) | 7 (0.24) | .738 | 2 (0.16) | 2 (0.06) | .219 |
| Myocardial infarction | 12 (0.21) | 3 (0.11) | 9 (0.30) | .094 | 0 (0) | 5 (0.14) | .234 |
| Cardiovascular death | 181 (3.13) | 98 (3.48) | 83 (2.79) | .132 | 38 (2.98) | 46 (1.31) | <.001 |
| MACE+ | 397 (6.86) | 217 (7.71) | 180 (6.06) | .012 | 72 (5,65) | 86 (2.46) | <.001 |
| Heart failure | 123 (2.13) | 74 (2.63) | 49 (1.65) | .011 | 17 (1.33) | 20 (0.57) | .005 |
| Stroke | 24 (0.41) | 13 (0.46) | 11 (0.37) | .597 | 4 (0.31) | 4 (0.11) | .127 |
| Unstable angina | 15 (0.26) | 8 (0.28) | 7 (0.24) | .738 | 2 (0.16) | 2 (0.06) | .219 |
| Myocardial infarction | 12 (0.21) | 3 (0.11) | 9 (0.30) | .094 | 0 (0) | 5 (0.14) | .234 |
| All-cause death | 264 (4.56) | 143 (5.08) | 121 (4.07) | .070 | 55 (4.31) | 65 (1.86) | <.001 |
| Hospitalization | 1252 (21.63) | 650 (23.08) | 602 (20.26) | .034 | 230 (18.03) | 448 (12.81) | <.001 |
| Infection | 439 (7.58) | 216 (7.67) | 223 (7.50) | .880 | 57 (10.35) | 124 (3.54) | <.001 |
| Cardiovascular disease | 183 (3.16) | 105 (3.73) | 78 (2.62)x | .023 | 33 (4.47) | 45 (1.29) | <.001 |
| Catheter-related non-infectious complications | 154 (2.66) | 71 (2.52) | 83 (2.79) | .502 | 27 (2.91) | 68 (1.94) | .003 |
| Transfer to HD | 229 (3.96) | 119 (4.23) | 110 (3.70) | .485 | 36 (2.82) | 68 (1.94) | .088 |
| Severe fluid overload | 89 (1.54) | 52 (1.85) | 37 (1.25) | .063 | 18 (1.41) | 30 (0.86) | .119 |
| PD-related infection | 74 (1.28) | 38 (1.35) | 36 (1.21) | .635 | 9 (0.71) | 20 (0.57) | .657 |
| Complications related to increased intra-abdominal pressure | 19 (0.33) | 8 (0.28) | 11 (0.37) | .576 | 1 (0.08) | 8 (0.29) | .281 |
| Socio-economic causes | 14 (0.24) | 4 (0.14) | 10 (0.34) | .134 | 2 (0.16) | 4 (0.11) | .578 |
| Inadequate solute clearance | 13 (0.22) | 4 (0.14) | 9 (0.30) | .210 | 5 (0.39) | 1 (0.03) | .019 |
| Catheter-related non-infectious complications | 12 (0.21) | 8 (0.28) | 4 (0.13) | .227 | 1 (0.08) | 1 (0.03) | .513 |
| Unknown or other | 8 (0.14) | 5 (0.18) | 3 (0.10) | .428 | 0 (0) | 4 (0.11) | .271 |
| First-episode peritonitis | 420 (7.26) | 206 (7.32) | 214 (7.20) | .850 | 31 (2.49) | 111 (3.27) | .106 |
| Outcome . | Total cohort (N = 2519), n (%) . | Hb <100 g/l (n = 1254), n (%) . | Hb ≥100 g/l (n = 1265), n (%) . | P-value . | Time-averaged Hb <100 g/l (n = 529), n (%) . | Time-averaged Hb ≥100 g/l (n = 1318), n (%) . | P-value . |
|---|---|---|---|---|---|---|---|
| Death | 264 (4.56) | 143 (5.08) | 121 (4.07) | .070 | 55 (4.31) | 65 (1.86) | <.001 |
| Cardiovascular events | 181 (3.13) | 98 (3.48) | 83 (2.79) | .132 | 38 (2.98) | 46 (1.31) | <.001 |
| Infection | 22 (0.38) | 11 (0.39) | 11 (0.37) | .881 | 4 (0.31) | 7 (0.20) | .410 |
| Tumour | 14 (0.24) | 8 (0.28) | 6 (0.20) | .523 | 3 (0.24) | 3 (0.09) | .156 |
| Severe malnutrition | 12 (0.21) | 6 (0.21) | 6 (0.20) | .932 | 3 (0.24) | 2 (0.06) | .074 |
| Multi-organ failure | 7 (0.12) | 5 (0.18) | 2 (0.07) | .231 | 1 (0.08) | 1 (0.03) | .478 |
| Gastrointestinal haemorrhage | 5 (0.09) | 2 (0.07) | 3 (0.10) | .686 | 1 (0.08) | 1 (0.03) | .372 |
| Unknown or miscellaneous | 23 (0.40) | 13 (0.46) | 10 (0.34) | .443 | 5 (0.39) | 5 (0.14) | .071 |
| MACE | 218 (3.77) | 115 (4.08) | 103 (3.47) | .225 | 42 (3.29) | 52 (1.49) | <.001 |
| Stroke | 24 (0.41) | 13 (0.46) | 11 (0.37) | .597 | 4 (0.31) | 4 (0.11) | .127 |
| Unstable angina | 15 (0.26) | 8 (0.28) | 7 (0.24) | .738 | 2 (0.16) | 2 (0.06) | .219 |
| Myocardial infarction | 12 (0.21) | 3 (0.11) | 9 (0.30) | .094 | 0 (0) | 5 (0.14) | .234 |
| Cardiovascular death | 181 (3.13) | 98 (3.48) | 83 (2.79) | .132 | 38 (2.98) | 46 (1.31) | <.001 |
| MACE+ | 397 (6.86) | 217 (7.71) | 180 (6.06) | .012 | 72 (5,65) | 86 (2.46) | <.001 |
| Heart failure | 123 (2.13) | 74 (2.63) | 49 (1.65) | .011 | 17 (1.33) | 20 (0.57) | .005 |
| Stroke | 24 (0.41) | 13 (0.46) | 11 (0.37) | .597 | 4 (0.31) | 4 (0.11) | .127 |
| Unstable angina | 15 (0.26) | 8 (0.28) | 7 (0.24) | .738 | 2 (0.16) | 2 (0.06) | .219 |
| Myocardial infarction | 12 (0.21) | 3 (0.11) | 9 (0.30) | .094 | 0 (0) | 5 (0.14) | .234 |
| All-cause death | 264 (4.56) | 143 (5.08) | 121 (4.07) | .070 | 55 (4.31) | 65 (1.86) | <.001 |
| Hospitalization | 1252 (21.63) | 650 (23.08) | 602 (20.26) | .034 | 230 (18.03) | 448 (12.81) | <.001 |
| Infection | 439 (7.58) | 216 (7.67) | 223 (7.50) | .880 | 57 (10.35) | 124 (3.54) | <.001 |
| Cardiovascular disease | 183 (3.16) | 105 (3.73) | 78 (2.62)x | .023 | 33 (4.47) | 45 (1.29) | <.001 |
| Catheter-related non-infectious complications | 154 (2.66) | 71 (2.52) | 83 (2.79) | .502 | 27 (2.91) | 68 (1.94) | .003 |
| Transfer to HD | 229 (3.96) | 119 (4.23) | 110 (3.70) | .485 | 36 (2.82) | 68 (1.94) | .088 |
| Severe fluid overload | 89 (1.54) | 52 (1.85) | 37 (1.25) | .063 | 18 (1.41) | 30 (0.86) | .119 |
| PD-related infection | 74 (1.28) | 38 (1.35) | 36 (1.21) | .635 | 9 (0.71) | 20 (0.57) | .657 |
| Complications related to increased intra-abdominal pressure | 19 (0.33) | 8 (0.28) | 11 (0.37) | .576 | 1 (0.08) | 8 (0.29) | .281 |
| Socio-economic causes | 14 (0.24) | 4 (0.14) | 10 (0.34) | .134 | 2 (0.16) | 4 (0.11) | .578 |
| Inadequate solute clearance | 13 (0.22) | 4 (0.14) | 9 (0.30) | .210 | 5 (0.39) | 1 (0.03) | .019 |
| Catheter-related non-infectious complications | 12 (0.21) | 8 (0.28) | 4 (0.13) | .227 | 1 (0.08) | 1 (0.03) | .513 |
| Unknown or other | 8 (0.14) | 5 (0.18) | 3 (0.10) | .428 | 0 (0) | 4 (0.11) | .271 |
| First-episode peritonitis | 420 (7.26) | 206 (7.32) | 214 (7.20) | .850 | 31 (2.49) | 111 (3.27) | .106 |
MACE includes myocardial infarction, unstable angina, stroke and cardiovascular deaths.
| Outcome . | Total cohort (N = 2519), n (%) . | Hb <100 g/l (n = 1254), n (%) . | Hb ≥100 g/l (n = 1265), n (%) . | P-value . | Time-averaged Hb <100 g/l (n = 529), n (%) . | Time-averaged Hb ≥100 g/l (n = 1318), n (%) . | P-value . |
|---|---|---|---|---|---|---|---|
| Death | 264 (4.56) | 143 (5.08) | 121 (4.07) | .070 | 55 (4.31) | 65 (1.86) | <.001 |
| Cardiovascular events | 181 (3.13) | 98 (3.48) | 83 (2.79) | .132 | 38 (2.98) | 46 (1.31) | <.001 |
| Infection | 22 (0.38) | 11 (0.39) | 11 (0.37) | .881 | 4 (0.31) | 7 (0.20) | .410 |
| Tumour | 14 (0.24) | 8 (0.28) | 6 (0.20) | .523 | 3 (0.24) | 3 (0.09) | .156 |
| Severe malnutrition | 12 (0.21) | 6 (0.21) | 6 (0.20) | .932 | 3 (0.24) | 2 (0.06) | .074 |
| Multi-organ failure | 7 (0.12) | 5 (0.18) | 2 (0.07) | .231 | 1 (0.08) | 1 (0.03) | .478 |
| Gastrointestinal haemorrhage | 5 (0.09) | 2 (0.07) | 3 (0.10) | .686 | 1 (0.08) | 1 (0.03) | .372 |
| Unknown or miscellaneous | 23 (0.40) | 13 (0.46) | 10 (0.34) | .443 | 5 (0.39) | 5 (0.14) | .071 |
| MACE | 218 (3.77) | 115 (4.08) | 103 (3.47) | .225 | 42 (3.29) | 52 (1.49) | <.001 |
| Stroke | 24 (0.41) | 13 (0.46) | 11 (0.37) | .597 | 4 (0.31) | 4 (0.11) | .127 |
| Unstable angina | 15 (0.26) | 8 (0.28) | 7 (0.24) | .738 | 2 (0.16) | 2 (0.06) | .219 |
| Myocardial infarction | 12 (0.21) | 3 (0.11) | 9 (0.30) | .094 | 0 (0) | 5 (0.14) | .234 |
| Cardiovascular death | 181 (3.13) | 98 (3.48) | 83 (2.79) | .132 | 38 (2.98) | 46 (1.31) | <.001 |
| MACE+ | 397 (6.86) | 217 (7.71) | 180 (6.06) | .012 | 72 (5,65) | 86 (2.46) | <.001 |
| Heart failure | 123 (2.13) | 74 (2.63) | 49 (1.65) | .011 | 17 (1.33) | 20 (0.57) | .005 |
| Stroke | 24 (0.41) | 13 (0.46) | 11 (0.37) | .597 | 4 (0.31) | 4 (0.11) | .127 |
| Unstable angina | 15 (0.26) | 8 (0.28) | 7 (0.24) | .738 | 2 (0.16) | 2 (0.06) | .219 |
| Myocardial infarction | 12 (0.21) | 3 (0.11) | 9 (0.30) | .094 | 0 (0) | 5 (0.14) | .234 |
| All-cause death | 264 (4.56) | 143 (5.08) | 121 (4.07) | .070 | 55 (4.31) | 65 (1.86) | <.001 |
| Hospitalization | 1252 (21.63) | 650 (23.08) | 602 (20.26) | .034 | 230 (18.03) | 448 (12.81) | <.001 |
| Infection | 439 (7.58) | 216 (7.67) | 223 (7.50) | .880 | 57 (10.35) | 124 (3.54) | <.001 |
| Cardiovascular disease | 183 (3.16) | 105 (3.73) | 78 (2.62)x | .023 | 33 (4.47) | 45 (1.29) | <.001 |
| Catheter-related non-infectious complications | 154 (2.66) | 71 (2.52) | 83 (2.79) | .502 | 27 (2.91) | 68 (1.94) | .003 |
| Transfer to HD | 229 (3.96) | 119 (4.23) | 110 (3.70) | .485 | 36 (2.82) | 68 (1.94) | .088 |
| Severe fluid overload | 89 (1.54) | 52 (1.85) | 37 (1.25) | .063 | 18 (1.41) | 30 (0.86) | .119 |
| PD-related infection | 74 (1.28) | 38 (1.35) | 36 (1.21) | .635 | 9 (0.71) | 20 (0.57) | .657 |
| Complications related to increased intra-abdominal pressure | 19 (0.33) | 8 (0.28) | 11 (0.37) | .576 | 1 (0.08) | 8 (0.29) | .281 |
| Socio-economic causes | 14 (0.24) | 4 (0.14) | 10 (0.34) | .134 | 2 (0.16) | 4 (0.11) | .578 |
| Inadequate solute clearance | 13 (0.22) | 4 (0.14) | 9 (0.30) | .210 | 5 (0.39) | 1 (0.03) | .019 |
| Catheter-related non-infectious complications | 12 (0.21) | 8 (0.28) | 4 (0.13) | .227 | 1 (0.08) | 1 (0.03) | .513 |
| Unknown or other | 8 (0.14) | 5 (0.18) | 3 (0.10) | .428 | 0 (0) | 4 (0.11) | .271 |
| First-episode peritonitis | 420 (7.26) | 206 (7.32) | 214 (7.20) | .850 | 31 (2.49) | 111 (3.27) | .106 |
| Outcome . | Total cohort (N = 2519), n (%) . | Hb <100 g/l (n = 1254), n (%) . | Hb ≥100 g/l (n = 1265), n (%) . | P-value . | Time-averaged Hb <100 g/l (n = 529), n (%) . | Time-averaged Hb ≥100 g/l (n = 1318), n (%) . | P-value . |
|---|---|---|---|---|---|---|---|
| Death | 264 (4.56) | 143 (5.08) | 121 (4.07) | .070 | 55 (4.31) | 65 (1.86) | <.001 |
| Cardiovascular events | 181 (3.13) | 98 (3.48) | 83 (2.79) | .132 | 38 (2.98) | 46 (1.31) | <.001 |
| Infection | 22 (0.38) | 11 (0.39) | 11 (0.37) | .881 | 4 (0.31) | 7 (0.20) | .410 |
| Tumour | 14 (0.24) | 8 (0.28) | 6 (0.20) | .523 | 3 (0.24) | 3 (0.09) | .156 |
| Severe malnutrition | 12 (0.21) | 6 (0.21) | 6 (0.20) | .932 | 3 (0.24) | 2 (0.06) | .074 |
| Multi-organ failure | 7 (0.12) | 5 (0.18) | 2 (0.07) | .231 | 1 (0.08) | 1 (0.03) | .478 |
| Gastrointestinal haemorrhage | 5 (0.09) | 2 (0.07) | 3 (0.10) | .686 | 1 (0.08) | 1 (0.03) | .372 |
| Unknown or miscellaneous | 23 (0.40) | 13 (0.46) | 10 (0.34) | .443 | 5 (0.39) | 5 (0.14) | .071 |
| MACE | 218 (3.77) | 115 (4.08) | 103 (3.47) | .225 | 42 (3.29) | 52 (1.49) | <.001 |
| Stroke | 24 (0.41) | 13 (0.46) | 11 (0.37) | .597 | 4 (0.31) | 4 (0.11) | .127 |
| Unstable angina | 15 (0.26) | 8 (0.28) | 7 (0.24) | .738 | 2 (0.16) | 2 (0.06) | .219 |
| Myocardial infarction | 12 (0.21) | 3 (0.11) | 9 (0.30) | .094 | 0 (0) | 5 (0.14) | .234 |
| Cardiovascular death | 181 (3.13) | 98 (3.48) | 83 (2.79) | .132 | 38 (2.98) | 46 (1.31) | <.001 |
| MACE+ | 397 (6.86) | 217 (7.71) | 180 (6.06) | .012 | 72 (5,65) | 86 (2.46) | <.001 |
| Heart failure | 123 (2.13) | 74 (2.63) | 49 (1.65) | .011 | 17 (1.33) | 20 (0.57) | .005 |
| Stroke | 24 (0.41) | 13 (0.46) | 11 (0.37) | .597 | 4 (0.31) | 4 (0.11) | .127 |
| Unstable angina | 15 (0.26) | 8 (0.28) | 7 (0.24) | .738 | 2 (0.16) | 2 (0.06) | .219 |
| Myocardial infarction | 12 (0.21) | 3 (0.11) | 9 (0.30) | .094 | 0 (0) | 5 (0.14) | .234 |
| All-cause death | 264 (4.56) | 143 (5.08) | 121 (4.07) | .070 | 55 (4.31) | 65 (1.86) | <.001 |
| Hospitalization | 1252 (21.63) | 650 (23.08) | 602 (20.26) | .034 | 230 (18.03) | 448 (12.81) | <.001 |
| Infection | 439 (7.58) | 216 (7.67) | 223 (7.50) | .880 | 57 (10.35) | 124 (3.54) | <.001 |
| Cardiovascular disease | 183 (3.16) | 105 (3.73) | 78 (2.62)x | .023 | 33 (4.47) | 45 (1.29) | <.001 |
| Catheter-related non-infectious complications | 154 (2.66) | 71 (2.52) | 83 (2.79) | .502 | 27 (2.91) | 68 (1.94) | .003 |
| Transfer to HD | 229 (3.96) | 119 (4.23) | 110 (3.70) | .485 | 36 (2.82) | 68 (1.94) | .088 |
| Severe fluid overload | 89 (1.54) | 52 (1.85) | 37 (1.25) | .063 | 18 (1.41) | 30 (0.86) | .119 |
| PD-related infection | 74 (1.28) | 38 (1.35) | 36 (1.21) | .635 | 9 (0.71) | 20 (0.57) | .657 |
| Complications related to increased intra-abdominal pressure | 19 (0.33) | 8 (0.28) | 11 (0.37) | .576 | 1 (0.08) | 8 (0.29) | .281 |
| Socio-economic causes | 14 (0.24) | 4 (0.14) | 10 (0.34) | .134 | 2 (0.16) | 4 (0.11) | .578 |
| Inadequate solute clearance | 13 (0.22) | 4 (0.14) | 9 (0.30) | .210 | 5 (0.39) | 1 (0.03) | .019 |
| Catheter-related non-infectious complications | 12 (0.21) | 8 (0.28) | 4 (0.13) | .227 | 1 (0.08) | 1 (0.03) | .513 |
| Unknown or other | 8 (0.14) | 5 (0.18) | 3 (0.10) | .428 | 0 (0) | 4 (0.11) | .271 |
| First-episode peritonitis | 420 (7.26) | 206 (7.32) | 214 (7.20) | .850 | 31 (2.49) | 111 (3.27) | .106 |
MACE includes myocardial infarction, unstable angina, stroke and cardiovascular deaths.
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