Table 3.
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Association between several potential determinants explaining the trajectory membership of the four determined trajectories (slow decline, intermediate decline, fast decline and increase)

Potential determinantaOdds ratio (95% CI)
Sex, women
 Slow eGFR declineReference
 Intermediate eGFR decline0.96 (0.77–1.20)
 Fast eGFR decline0.54 (0.38–0.75)*
 Increase/stable1.94 (1.53–2.46)*
Sex, men
 Slow eGFR declineReference
 Intermediate eGFR decline1.03 (0.86–1.25)
 Fast eGFR decline1.86 (1.33–2.60)*
 Increase/stable0.52 (0.41–0.65)*
Hypertension
 Slow eGFR declineReference
 Intermediate eGFR decline2.55 (2.05–3.17)*
 Fast eGFR decline3.38 (2.14–5.35)*
 Increase/stable1.89 (1.51–2.35)*
Diabetes
 Slow eGFR declineReference
 Intermediate eGFR decline1.81 (1.45–2.26)*
 Fast eGFR decline4.65 (3.29–6.58)*
 Increase/stable1.27 (0.95–1.69)
Prevalent CVD
 Slow eGFR declineReference
 Intermediate eGFR decline1.53 (1.16–2.00)*
 Fast eGFR decline1.56 (0.99–2.48)
 Increase/stable1.31 (0.90–1.89)
Potential determinantaOdds ratio (95% CI)
Sex, women
 Slow eGFR declineReference
 Intermediate eGFR decline0.96 (0.77–1.20)
 Fast eGFR decline0.54 (0.38–0.75)*
 Increase/stable1.94 (1.53–2.46)*
Sex, men
 Slow eGFR declineReference
 Intermediate eGFR decline1.03 (0.86–1.25)
 Fast eGFR decline1.86 (1.33–2.60)*
 Increase/stable0.52 (0.41–0.65)*
Hypertension
 Slow eGFR declineReference
 Intermediate eGFR decline2.55 (2.05–3.17)*
 Fast eGFR decline3.38 (2.14–5.35)*
 Increase/stable1.89 (1.51–2.35)*
Diabetes
 Slow eGFR declineReference
 Intermediate eGFR decline1.81 (1.45–2.26)*
 Fast eGFR decline4.65 (3.29–6.58)*
 Increase/stable1.27 (0.95–1.69)
Prevalent CVD
 Slow eGFR declineReference
 Intermediate eGFR decline1.53 (1.16–2.00)*
 Fast eGFR decline1.56 (0.99–2.48)
 Increase/stable1.31 (0.90–1.89)
a

Women compared with men or vice versa; hypertension compared with no hypertension; diabetes compared with no diabetes; prevalent CVD compared with no prevalent CVD.

*

P < 0.05.

CVD, cardiovascular disease; eGFR, estimated glomerular filtration rate.

Table 3.
Open in new tab

Association between several potential determinants explaining the trajectory membership of the four determined trajectories (slow decline, intermediate decline, fast decline and increase)

Potential determinantaOdds ratio (95% CI)
Sex, women
 Slow eGFR declineReference
 Intermediate eGFR decline0.96 (0.77–1.20)
 Fast eGFR decline0.54 (0.38–0.75)*
 Increase/stable1.94 (1.53–2.46)*
Sex, men
 Slow eGFR declineReference
 Intermediate eGFR decline1.03 (0.86–1.25)
 Fast eGFR decline1.86 (1.33–2.60)*
 Increase/stable0.52 (0.41–0.65)*
Hypertension
 Slow eGFR declineReference
 Intermediate eGFR decline2.55 (2.05–3.17)*
 Fast eGFR decline3.38 (2.14–5.35)*
 Increase/stable1.89 (1.51–2.35)*
Diabetes
 Slow eGFR declineReference
 Intermediate eGFR decline1.81 (1.45–2.26)*
 Fast eGFR decline4.65 (3.29–6.58)*
 Increase/stable1.27 (0.95–1.69)
Prevalent CVD
 Slow eGFR declineReference
 Intermediate eGFR decline1.53 (1.16–2.00)*
 Fast eGFR decline1.56 (0.99–2.48)
 Increase/stable1.31 (0.90–1.89)
Potential determinantaOdds ratio (95% CI)
Sex, women
 Slow eGFR declineReference
 Intermediate eGFR decline0.96 (0.77–1.20)
 Fast eGFR decline0.54 (0.38–0.75)*
 Increase/stable1.94 (1.53–2.46)*
Sex, men
 Slow eGFR declineReference
 Intermediate eGFR decline1.03 (0.86–1.25)
 Fast eGFR decline1.86 (1.33–2.60)*
 Increase/stable0.52 (0.41–0.65)*
Hypertension
 Slow eGFR declineReference
 Intermediate eGFR decline2.55 (2.05–3.17)*
 Fast eGFR decline3.38 (2.14–5.35)*
 Increase/stable1.89 (1.51–2.35)*
Diabetes
 Slow eGFR declineReference
 Intermediate eGFR decline1.81 (1.45–2.26)*
 Fast eGFR decline4.65 (3.29–6.58)*
 Increase/stable1.27 (0.95–1.69)
Prevalent CVD
 Slow eGFR declineReference
 Intermediate eGFR decline1.53 (1.16–2.00)*
 Fast eGFR decline1.56 (0.99–2.48)
 Increase/stable1.31 (0.90–1.89)
a

Women compared with men or vice versa; hypertension compared with no hypertension; diabetes compared with no diabetes; prevalent CVD compared with no prevalent CVD.

*

P < 0.05.

CVD, cardiovascular disease; eGFR, estimated glomerular filtration rate.

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