Incidence of neonatal adverse outcomes in relation to motor vehicle crashes of various injury severity levels during pregnancy among live-born offspring in Taiwan, 2007–16
Injury severity levels . | Total . | Fetal distress . | Intrauterine hypoxia and birth asphyxia . | Respiratory distress syndrome . | Birth defects . | ||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adverse outcome . | Crude . | Adjusteda . | Adverse outcome . | Crude . | Adjusteda . | Adverse outcome . | Crude . | Adjusteda . | Adverse outcome . | Crude . | Adjusteda . | ||||||||||||||
n . | % . | OR . | 95% CI . | OR . | 95% CI . | n . | % . | OR . | 95% CI . | OR . | 95% CI . | n . | % . | OR . | 95% CI . | OR . | 95% CI . | n . | % . | OR . | 95% CI . | OR . | 95% CI . | ||
Without MVC | 76 015 | 1173 | 1.5 | 1.00 | Reference | 1.00 | Reference | 238 | 0.3 | 1.00 | Reference | 1.00 | Reference | 524 | 0.7 | 1.00 | Reference | 1.00 | Reference | 714 | 0.9 | 1.00 | Reference | 1.00 | Reference |
With MVC during pregnancy | 19 277 | 319 | 1.7 | 1.07 | 0.95–1.22 | 1.05 | 0.93–1.20 | 55 | 0.3 | 0.91 | 0.68–1.22 | 0.92 | 0.68–1.24 | 144 | 0.8 | 1.08 | 0.90–1.31 | 1.05 | 0.86–1.28 | 226 | 1.2 | 1.25 | 1.08–1.45 | 1.21 | 1.04–1.41 |
Without any clinical visit | 5255 | 87 | 1.7 | 1.07 | 0.86–1.34 | 1.09 | 0.87–1.37 | 14 | 0.3 | 0.85 | 0.50–1.46 | 0.84 | 0.49–1.44 | 33 | 0.6 | 0.91 | 0.64–1.30 | 0.87 | 0.60–1.26 | 61 | 1.2 | 1.24 | 0.95–1.61 | 1.17 | 0.89–1.53 |
With clinical visit but no injury | 4507 | 73 | 1.6 | 1.05 | 0.83–1.33 | 1.08 | 0.85–1.38 | 8 | 0.2 | 0.57 | 0.28–1.15 | 0.65 | 0.32–1.32 | 25 | 0.6 | 0.80 | 0.54–1.20 | 0.85 | 0.55–1.30 | 39 | 0.9 | 0.92 | 0.67–1.27 | 0.85 | 0.68–1.32 |
With clinical visit and mild injury | 9274 | 153 | 1.7 | 1.07 | 0.90–1.27 | 1.02 | 0.86–1.22 | 31 | 0.3 | 1.07 | 0.73–1.55 | 1.07 | 0.73–1.56 | 80 | 0.9 | 1.25 | 0.99–1.59 | 1.19 | 0.93–1.53 | 119 | 1.3 | 1.37 | 1.13–1.67 | 1.31 | 1.07–1.60 |
With clinical visit and severe injury | 241 | 6 | 2.5 | 1.63 | 0.72–3.67 | 1.07 | 0.46–2.47 | 2 | 0.8 | 2.67 | 0.66–10.78 | 2.21 | 0.54–9.03 | 6 | 2.5 | 3.68 | 1.63–8.31 | 2.17 | 0.88–5.36 | 7 | 2.9 | 3.16 | 1.48–6.72 | 2.43 | 1.11–5.30 |
P for trend | 0.3417 | 0.0272 | 0.0026 | 0.0023 |
Injury severity levels . | Total . | Fetal distress . | Intrauterine hypoxia and birth asphyxia . | Respiratory distress syndrome . | Birth defects . | ||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adverse outcome . | Crude . | Adjusteda . | Adverse outcome . | Crude . | Adjusteda . | Adverse outcome . | Crude . | Adjusteda . | Adverse outcome . | Crude . | Adjusteda . | ||||||||||||||
n . | % . | OR . | 95% CI . | OR . | 95% CI . | n . | % . | OR . | 95% CI . | OR . | 95% CI . | n . | % . | OR . | 95% CI . | OR . | 95% CI . | n . | % . | OR . | 95% CI . | OR . | 95% CI . | ||
Without MVC | 76 015 | 1173 | 1.5 | 1.00 | Reference | 1.00 | Reference | 238 | 0.3 | 1.00 | Reference | 1.00 | Reference | 524 | 0.7 | 1.00 | Reference | 1.00 | Reference | 714 | 0.9 | 1.00 | Reference | 1.00 | Reference |
With MVC during pregnancy | 19 277 | 319 | 1.7 | 1.07 | 0.95–1.22 | 1.05 | 0.93–1.20 | 55 | 0.3 | 0.91 | 0.68–1.22 | 0.92 | 0.68–1.24 | 144 | 0.8 | 1.08 | 0.90–1.31 | 1.05 | 0.86–1.28 | 226 | 1.2 | 1.25 | 1.08–1.45 | 1.21 | 1.04–1.41 |
Without any clinical visit | 5255 | 87 | 1.7 | 1.07 | 0.86–1.34 | 1.09 | 0.87–1.37 | 14 | 0.3 | 0.85 | 0.50–1.46 | 0.84 | 0.49–1.44 | 33 | 0.6 | 0.91 | 0.64–1.30 | 0.87 | 0.60–1.26 | 61 | 1.2 | 1.24 | 0.95–1.61 | 1.17 | 0.89–1.53 |
With clinical visit but no injury | 4507 | 73 | 1.6 | 1.05 | 0.83–1.33 | 1.08 | 0.85–1.38 | 8 | 0.2 | 0.57 | 0.28–1.15 | 0.65 | 0.32–1.32 | 25 | 0.6 | 0.80 | 0.54–1.20 | 0.85 | 0.55–1.30 | 39 | 0.9 | 0.92 | 0.67–1.27 | 0.85 | 0.68–1.32 |
With clinical visit and mild injury | 9274 | 153 | 1.7 | 1.07 | 0.90–1.27 | 1.02 | 0.86–1.22 | 31 | 0.3 | 1.07 | 0.73–1.55 | 1.07 | 0.73–1.56 | 80 | 0.9 | 1.25 | 0.99–1.59 | 1.19 | 0.93–1.53 | 119 | 1.3 | 1.37 | 1.13–1.67 | 1.31 | 1.07–1.60 |
With clinical visit and severe injury | 241 | 6 | 2.5 | 1.63 | 0.72–3.67 | 1.07 | 0.46–2.47 | 2 | 0.8 | 2.67 | 0.66–10.78 | 2.21 | 0.54–9.03 | 6 | 2.5 | 3.68 | 1.63–8.31 | 2.17 | 0.88–5.36 | 7 | 2.9 | 3.16 | 1.48–6.72 | 2.43 | 1.11–5.30 |
P for trend | 0.3417 | 0.0272 | 0.0026 | 0.0023 |
OR, odds ratio; MVC, motor vehicle crash.
Adjusted for all variables listed in Table 1.
Incidence of neonatal adverse outcomes in relation to motor vehicle crashes of various injury severity levels during pregnancy among live-born offspring in Taiwan, 2007–16
Injury severity levels . | Total . | Fetal distress . | Intrauterine hypoxia and birth asphyxia . | Respiratory distress syndrome . | Birth defects . | ||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adverse outcome . | Crude . | Adjusteda . | Adverse outcome . | Crude . | Adjusteda . | Adverse outcome . | Crude . | Adjusteda . | Adverse outcome . | Crude . | Adjusteda . | ||||||||||||||
n . | % . | OR . | 95% CI . | OR . | 95% CI . | n . | % . | OR . | 95% CI . | OR . | 95% CI . | n . | % . | OR . | 95% CI . | OR . | 95% CI . | n . | % . | OR . | 95% CI . | OR . | 95% CI . | ||
Without MVC | 76 015 | 1173 | 1.5 | 1.00 | Reference | 1.00 | Reference | 238 | 0.3 | 1.00 | Reference | 1.00 | Reference | 524 | 0.7 | 1.00 | Reference | 1.00 | Reference | 714 | 0.9 | 1.00 | Reference | 1.00 | Reference |
With MVC during pregnancy | 19 277 | 319 | 1.7 | 1.07 | 0.95–1.22 | 1.05 | 0.93–1.20 | 55 | 0.3 | 0.91 | 0.68–1.22 | 0.92 | 0.68–1.24 | 144 | 0.8 | 1.08 | 0.90–1.31 | 1.05 | 0.86–1.28 | 226 | 1.2 | 1.25 | 1.08–1.45 | 1.21 | 1.04–1.41 |
Without any clinical visit | 5255 | 87 | 1.7 | 1.07 | 0.86–1.34 | 1.09 | 0.87–1.37 | 14 | 0.3 | 0.85 | 0.50–1.46 | 0.84 | 0.49–1.44 | 33 | 0.6 | 0.91 | 0.64–1.30 | 0.87 | 0.60–1.26 | 61 | 1.2 | 1.24 | 0.95–1.61 | 1.17 | 0.89–1.53 |
With clinical visit but no injury | 4507 | 73 | 1.6 | 1.05 | 0.83–1.33 | 1.08 | 0.85–1.38 | 8 | 0.2 | 0.57 | 0.28–1.15 | 0.65 | 0.32–1.32 | 25 | 0.6 | 0.80 | 0.54–1.20 | 0.85 | 0.55–1.30 | 39 | 0.9 | 0.92 | 0.67–1.27 | 0.85 | 0.68–1.32 |
With clinical visit and mild injury | 9274 | 153 | 1.7 | 1.07 | 0.90–1.27 | 1.02 | 0.86–1.22 | 31 | 0.3 | 1.07 | 0.73–1.55 | 1.07 | 0.73–1.56 | 80 | 0.9 | 1.25 | 0.99–1.59 | 1.19 | 0.93–1.53 | 119 | 1.3 | 1.37 | 1.13–1.67 | 1.31 | 1.07–1.60 |
With clinical visit and severe injury | 241 | 6 | 2.5 | 1.63 | 0.72–3.67 | 1.07 | 0.46–2.47 | 2 | 0.8 | 2.67 | 0.66–10.78 | 2.21 | 0.54–9.03 | 6 | 2.5 | 3.68 | 1.63–8.31 | 2.17 | 0.88–5.36 | 7 | 2.9 | 3.16 | 1.48–6.72 | 2.43 | 1.11–5.30 |
P for trend | 0.3417 | 0.0272 | 0.0026 | 0.0023 |
Injury severity levels . | Total . | Fetal distress . | Intrauterine hypoxia and birth asphyxia . | Respiratory distress syndrome . | Birth defects . | ||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adverse outcome . | Crude . | Adjusteda . | Adverse outcome . | Crude . | Adjusteda . | Adverse outcome . | Crude . | Adjusteda . | Adverse outcome . | Crude . | Adjusteda . | ||||||||||||||
n . | % . | OR . | 95% CI . | OR . | 95% CI . | n . | % . | OR . | 95% CI . | OR . | 95% CI . | n . | % . | OR . | 95% CI . | OR . | 95% CI . | n . | % . | OR . | 95% CI . | OR . | 95% CI . | ||
Without MVC | 76 015 | 1173 | 1.5 | 1.00 | Reference | 1.00 | Reference | 238 | 0.3 | 1.00 | Reference | 1.00 | Reference | 524 | 0.7 | 1.00 | Reference | 1.00 | Reference | 714 | 0.9 | 1.00 | Reference | 1.00 | Reference |
With MVC during pregnancy | 19 277 | 319 | 1.7 | 1.07 | 0.95–1.22 | 1.05 | 0.93–1.20 | 55 | 0.3 | 0.91 | 0.68–1.22 | 0.92 | 0.68–1.24 | 144 | 0.8 | 1.08 | 0.90–1.31 | 1.05 | 0.86–1.28 | 226 | 1.2 | 1.25 | 1.08–1.45 | 1.21 | 1.04–1.41 |
Without any clinical visit | 5255 | 87 | 1.7 | 1.07 | 0.86–1.34 | 1.09 | 0.87–1.37 | 14 | 0.3 | 0.85 | 0.50–1.46 | 0.84 | 0.49–1.44 | 33 | 0.6 | 0.91 | 0.64–1.30 | 0.87 | 0.60–1.26 | 61 | 1.2 | 1.24 | 0.95–1.61 | 1.17 | 0.89–1.53 |
With clinical visit but no injury | 4507 | 73 | 1.6 | 1.05 | 0.83–1.33 | 1.08 | 0.85–1.38 | 8 | 0.2 | 0.57 | 0.28–1.15 | 0.65 | 0.32–1.32 | 25 | 0.6 | 0.80 | 0.54–1.20 | 0.85 | 0.55–1.30 | 39 | 0.9 | 0.92 | 0.67–1.27 | 0.85 | 0.68–1.32 |
With clinical visit and mild injury | 9274 | 153 | 1.7 | 1.07 | 0.90–1.27 | 1.02 | 0.86–1.22 | 31 | 0.3 | 1.07 | 0.73–1.55 | 1.07 | 0.73–1.56 | 80 | 0.9 | 1.25 | 0.99–1.59 | 1.19 | 0.93–1.53 | 119 | 1.3 | 1.37 | 1.13–1.67 | 1.31 | 1.07–1.60 |
With clinical visit and severe injury | 241 | 6 | 2.5 | 1.63 | 0.72–3.67 | 1.07 | 0.46–2.47 | 2 | 0.8 | 2.67 | 0.66–10.78 | 2.21 | 0.54–9.03 | 6 | 2.5 | 3.68 | 1.63–8.31 | 2.17 | 0.88–5.36 | 7 | 2.9 | 3.16 | 1.48–6.72 | 2.43 | 1.11–5.30 |
P for trend | 0.3417 | 0.0272 | 0.0026 | 0.0023 |
OR, odds ratio; MVC, motor vehicle crash.
Adjusted for all variables listed in Table 1.
This PDF is available to Subscribers Only
View Article Abstract & Purchase OptionsFor full access to this pdf, sign in to an existing account, or purchase an annual subscription.