Angiographic, physiological, and imaging characteristics of the included vessels
| Vascular territory | n = 334 |
| Right coronary artery | 93 (28) |
| Left anterior descending artery | 127 (38) |
| Circumflex artery | 114 (34) |
| Anatomical lesion characteristics | |
| Lesion length (mm) | 16.3 (10.5–26.2) |
| Diameter stenosis (%) | 41 ± 14 |
| Intermediate lesions | 258 (77) |
| Area stenosis (%) | 56 ± 18 |
| Minimal lumen diameter (mm) | 1.7 ± 0.5 |
| Invasive physiology characteristics | |
| QFR | 0.92 (0.80–0.98) |
| QFR ≤0.80 | 85 (25) |
| FFR | 0.90 (0.82–0.96) |
| FFR ≤0.80 | 72 (22) |
| Grey zone FFR (≥0.75 and ≤0.85) | 78 (23) |
| PET (n = 329) | |
| Hyperaemic MBF (mL/min/g) | 2.79 ± 0.98 |
| Indicative of ischaemia | 127 (38) |
| SPECT (n = 325) | |
| SDS | 0 (0–1) |
| Perfusion defect percentage | 0 (0–5) |
| Normal scan | 162 (51) |
| Fixed perfusion defect | 57 (18) |
| Reversible perfusion defect | 55 (17) |
| Mixed perfusion defect | 51 (16) |
| Indicative of ischaemia | 106 (33) |
| CMR (LGE n = 328 and perfusion n = 306) | |
| LGE score | 0 (0–1) |
| MI | 76 (23) |
| Perfusion defect score | 0 (0–3) |
| Perfusion defect percentage | 0 (0–13) |
| Indicative of ischaemia | 64 (21) |
| Vascular territory | n = 334 |
| Right coronary artery | 93 (28) |
| Left anterior descending artery | 127 (38) |
| Circumflex artery | 114 (34) |
| Anatomical lesion characteristics | |
| Lesion length (mm) | 16.3 (10.5–26.2) |
| Diameter stenosis (%) | 41 ± 14 |
| Intermediate lesions | 258 (77) |
| Area stenosis (%) | 56 ± 18 |
| Minimal lumen diameter (mm) | 1.7 ± 0.5 |
| Invasive physiology characteristics | |
| QFR | 0.92 (0.80–0.98) |
| QFR ≤0.80 | 85 (25) |
| FFR | 0.90 (0.82–0.96) |
| FFR ≤0.80 | 72 (22) |
| Grey zone FFR (≥0.75 and ≤0.85) | 78 (23) |
| PET (n = 329) | |
| Hyperaemic MBF (mL/min/g) | 2.79 ± 0.98 |
| Indicative of ischaemia | 127 (38) |
| SPECT (n = 325) | |
| SDS | 0 (0–1) |
| Perfusion defect percentage | 0 (0–5) |
| Normal scan | 162 (51) |
| Fixed perfusion defect | 57 (18) |
| Reversible perfusion defect | 55 (17) |
| Mixed perfusion defect | 51 (16) |
| Indicative of ischaemia | 106 (33) |
| CMR (LGE n = 328 and perfusion n = 306) | |
| LGE score | 0 (0–1) |
| MI | 76 (23) |
| Perfusion defect score | 0 (0–3) |
| Perfusion defect percentage | 0 (0–13) |
| Indicative of ischaemia | 64 (21) |
Values are presented as mean ± SD, median (inter-quartile range), or absolute numbers (%).
Angiographic, physiological, and imaging characteristics of the included vessels
| Vascular territory | n = 334 |
| Right coronary artery | 93 (28) |
| Left anterior descending artery | 127 (38) |
| Circumflex artery | 114 (34) |
| Anatomical lesion characteristics | |
| Lesion length (mm) | 16.3 (10.5–26.2) |
| Diameter stenosis (%) | 41 ± 14 |
| Intermediate lesions | 258 (77) |
| Area stenosis (%) | 56 ± 18 |
| Minimal lumen diameter (mm) | 1.7 ± 0.5 |
| Invasive physiology characteristics | |
| QFR | 0.92 (0.80–0.98) |
| QFR ≤0.80 | 85 (25) |
| FFR | 0.90 (0.82–0.96) |
| FFR ≤0.80 | 72 (22) |
| Grey zone FFR (≥0.75 and ≤0.85) | 78 (23) |
| PET (n = 329) | |
| Hyperaemic MBF (mL/min/g) | 2.79 ± 0.98 |
| Indicative of ischaemia | 127 (38) |
| SPECT (n = 325) | |
| SDS | 0 (0–1) |
| Perfusion defect percentage | 0 (0–5) |
| Normal scan | 162 (51) |
| Fixed perfusion defect | 57 (18) |
| Reversible perfusion defect | 55 (17) |
| Mixed perfusion defect | 51 (16) |
| Indicative of ischaemia | 106 (33) |
| CMR (LGE n = 328 and perfusion n = 306) | |
| LGE score | 0 (0–1) |
| MI | 76 (23) |
| Perfusion defect score | 0 (0–3) |
| Perfusion defect percentage | 0 (0–13) |
| Indicative of ischaemia | 64 (21) |
| Vascular territory | n = 334 |
| Right coronary artery | 93 (28) |
| Left anterior descending artery | 127 (38) |
| Circumflex artery | 114 (34) |
| Anatomical lesion characteristics | |
| Lesion length (mm) | 16.3 (10.5–26.2) |
| Diameter stenosis (%) | 41 ± 14 |
| Intermediate lesions | 258 (77) |
| Area stenosis (%) | 56 ± 18 |
| Minimal lumen diameter (mm) | 1.7 ± 0.5 |
| Invasive physiology characteristics | |
| QFR | 0.92 (0.80–0.98) |
| QFR ≤0.80 | 85 (25) |
| FFR | 0.90 (0.82–0.96) |
| FFR ≤0.80 | 72 (22) |
| Grey zone FFR (≥0.75 and ≤0.85) | 78 (23) |
| PET (n = 329) | |
| Hyperaemic MBF (mL/min/g) | 2.79 ± 0.98 |
| Indicative of ischaemia | 127 (38) |
| SPECT (n = 325) | |
| SDS | 0 (0–1) |
| Perfusion defect percentage | 0 (0–5) |
| Normal scan | 162 (51) |
| Fixed perfusion defect | 57 (18) |
| Reversible perfusion defect | 55 (17) |
| Mixed perfusion defect | 51 (16) |
| Indicative of ischaemia | 106 (33) |
| CMR (LGE n = 328 and perfusion n = 306) | |
| LGE score | 0 (0–1) |
| MI | 76 (23) |
| Perfusion defect score | 0 (0–3) |
| Perfusion defect percentage | 0 (0–13) |
| Indicative of ischaemia | 64 (21) |
Values are presented as mean ± SD, median (inter-quartile range), or absolute numbers (%).
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