EQ-5D-3L cut-offs that yielded statistically significant separation between belimumab 10 mg/kg and placebo at week 52
| Health state . | EQ-5D-3L cut-off . | OR . | 95% CI . | P-value . |
|---|---|---|---|---|
| 11111 | 100.00 | 1.471 | 1.109, 1.955 | 0.008 |
| 11211 | 86.03 | 1.456 | 1.102, 1.927 | 0.008 |
| 21111 | 85.40 | 1.451 | 1.100, 1.917 | 0.009 |
| 11112 | 84.38 | 1.423 | 1.095, 1.851 | 0.008 |
| 21211 | 84.32 | 1.380 | 1.064, 1.791 | 0.015 |
| 11212 | 83.30 | 1.372 | 1.061, 1.778 | 0.016 |
| 11121 | 82.71 | 1.280 | 1.009, 1.623 | 0.042 |
| 21112 | 82.67 | 1.279 | 1.009, 1.623 | 0.042 |
| 11221 | 81.63 | 1.287 | 1.017, 1.630 | 0.036 |
| Health state . | EQ-5D-3L cut-off . | OR . | 95% CI . | P-value . |
|---|---|---|---|---|
| 11111 | 100.00 | 1.471 | 1.109, 1.955 | 0.008 |
| 11211 | 86.03 | 1.456 | 1.102, 1.927 | 0.008 |
| 21111 | 85.40 | 1.451 | 1.100, 1.917 | 0.009 |
| 11112 | 84.38 | 1.423 | 1.095, 1.851 | 0.008 |
| 21211 | 84.32 | 1.380 | 1.064, 1.791 | 0.015 |
| 11212 | 83.30 | 1.372 | 1.061, 1.778 | 0.016 |
| 11121 | 82.71 | 1.280 | 1.009, 1.623 | 0.042 |
| 21112 | 82.67 | 1.279 | 1.009, 1.623 | 0.042 |
| 11221 | 81.63 | 1.287 | 1.017, 1.630 | 0.036 |
EQ-5D index scores are multiplied by 100. The health states corresponding to the cut-offs are based on the US value set [20]. The numbers represent the level of each dimension of the EQ-5D-3L, in the order in which they are stated in the questionnaire (i.e. mobility, self-care, usual activities, pain/discomfort, anxiety/depression). No problems: level 1; some problems: level 2; extreme problems: level 3. Statistically significant P-values are in bold. EQ-5D-3L: three-level version of the EuroQol 5-Dimensions; OR: odds ratio.
EQ-5D-3L cut-offs that yielded statistically significant separation between belimumab 10 mg/kg and placebo at week 52
| Health state . | EQ-5D-3L cut-off . | OR . | 95% CI . | P-value . |
|---|---|---|---|---|
| 11111 | 100.00 | 1.471 | 1.109, 1.955 | 0.008 |
| 11211 | 86.03 | 1.456 | 1.102, 1.927 | 0.008 |
| 21111 | 85.40 | 1.451 | 1.100, 1.917 | 0.009 |
| 11112 | 84.38 | 1.423 | 1.095, 1.851 | 0.008 |
| 21211 | 84.32 | 1.380 | 1.064, 1.791 | 0.015 |
| 11212 | 83.30 | 1.372 | 1.061, 1.778 | 0.016 |
| 11121 | 82.71 | 1.280 | 1.009, 1.623 | 0.042 |
| 21112 | 82.67 | 1.279 | 1.009, 1.623 | 0.042 |
| 11221 | 81.63 | 1.287 | 1.017, 1.630 | 0.036 |
| Health state . | EQ-5D-3L cut-off . | OR . | 95% CI . | P-value . |
|---|---|---|---|---|
| 11111 | 100.00 | 1.471 | 1.109, 1.955 | 0.008 |
| 11211 | 86.03 | 1.456 | 1.102, 1.927 | 0.008 |
| 21111 | 85.40 | 1.451 | 1.100, 1.917 | 0.009 |
| 11112 | 84.38 | 1.423 | 1.095, 1.851 | 0.008 |
| 21211 | 84.32 | 1.380 | 1.064, 1.791 | 0.015 |
| 11212 | 83.30 | 1.372 | 1.061, 1.778 | 0.016 |
| 11121 | 82.71 | 1.280 | 1.009, 1.623 | 0.042 |
| 21112 | 82.67 | 1.279 | 1.009, 1.623 | 0.042 |
| 11221 | 81.63 | 1.287 | 1.017, 1.630 | 0.036 |
EQ-5D index scores are multiplied by 100. The health states corresponding to the cut-offs are based on the US value set [20]. The numbers represent the level of each dimension of the EQ-5D-3L, in the order in which they are stated in the questionnaire (i.e. mobility, self-care, usual activities, pain/discomfort, anxiety/depression). No problems: level 1; some problems: level 2; extreme problems: level 3. Statistically significant P-values are in bold. EQ-5D-3L: three-level version of the EuroQol 5-Dimensions; OR: odds ratio.
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