. | All patients (n = 774) . | Patients without SCD end points (n = 728) . | Patients with SCD end points (n = 46) . | P-value . |
---|---|---|---|---|
Left atrial diameter (mm) | 39 ± 8 | 39 ± 8 | 44 ± 9 | < .001 |
LV end-diastolic diameter (mm) | 48 ± 6 | 48 ± 6 | 51 ± 11 | .020 |
Maximal wall thickness (mm) | 21 ± 6 | 21 ± 6 | 25 ± 7 | < .001 |
Maximal wall thickness ≥30 mm | 66 (8.5) | 59 (8.1) | 7 (15.2) | .094 |
LV mass index (g/m2) | 82.3 ± 36.6 | 80.8 ± 34.4 | 106.8 ± 56.3 | .003 |
LV EDV index (mL/m2) | 67.9 ± 20.2 | 66.8 ± 17.1 | 84.7 ± 44.5 | .009 |
LV ESV index (mL/m2) | 23.5 ± 15.7 | 22.4 ± 12.1 | 41.6 ± 39.0 | .002 |
Stroke volume (mL) | 79.8 ± 20.9 | 79.9 ± 20.3 | 78.2 ± 28.7 | .700 |
Cardiac index (L/min/m2) | 3.0 ± .9 | 3.0 ± .8 | 3.2 ± 1.4 | .493 |
LV ejection fraction (%) | 66.5 ± 9.7 | 67.1 ± 8.6 | 56.2 ± 17.3 | < .001 |
LV ejection fraction <50% | 37 (4.8) | 22 (3.0) | 15 (32.6) | < .001 |
LVOT gradient (mmHg) | 36 ± 40 18 [8–64] | 36 ± 40 10 [8–64] | 40 ± 46 10 [7–67] | .563 |
LVOT obstruction, n (%) | 305 (39.4) | 287 (39.4) | 18 (39.1) | .969 |
Moderate to severe MR, n (%) | 129 (16.7) | 118 (16.2) | 11 (23.9) | .174 |
Apical aneurysm | 6 (.8) | 5 (.7) | 1 (2.2) | .265 |
LGE presence, n (%) | 476 (61.5) | 433 (59.5) | 43 (93.5) | < .001 |
LGE (%) | 5.5 ± 7.1 3.8 [0–7.7] | 4.9 ± 6.6 3.2 [0–7.1] | 13.7 ± 9.4 10.4 [6.7–19.6] | < .001 |
0% ≤ LGE < 5% | 457 (59.0) | 452 (58.4) | 5 (10.9) | |
5%≤ LGE < 10% | 192 (24.8) | 175 (24.0) | 17 (37.0) | |
10% ≤ LGE < 15% | 59 (7.6) | 52 (7.1) | 7 (15.2) | |
LGE ≥ 15% | 66 (8.5) | 49 (6.7) | 17 (37.0) |
. | All patients (n = 774) . | Patients without SCD end points (n = 728) . | Patients with SCD end points (n = 46) . | P-value . |
---|---|---|---|---|
Left atrial diameter (mm) | 39 ± 8 | 39 ± 8 | 44 ± 9 | < .001 |
LV end-diastolic diameter (mm) | 48 ± 6 | 48 ± 6 | 51 ± 11 | .020 |
Maximal wall thickness (mm) | 21 ± 6 | 21 ± 6 | 25 ± 7 | < .001 |
Maximal wall thickness ≥30 mm | 66 (8.5) | 59 (8.1) | 7 (15.2) | .094 |
LV mass index (g/m2) | 82.3 ± 36.6 | 80.8 ± 34.4 | 106.8 ± 56.3 | .003 |
LV EDV index (mL/m2) | 67.9 ± 20.2 | 66.8 ± 17.1 | 84.7 ± 44.5 | .009 |
LV ESV index (mL/m2) | 23.5 ± 15.7 | 22.4 ± 12.1 | 41.6 ± 39.0 | .002 |
Stroke volume (mL) | 79.8 ± 20.9 | 79.9 ± 20.3 | 78.2 ± 28.7 | .700 |
Cardiac index (L/min/m2) | 3.0 ± .9 | 3.0 ± .8 | 3.2 ± 1.4 | .493 |
LV ejection fraction (%) | 66.5 ± 9.7 | 67.1 ± 8.6 | 56.2 ± 17.3 | < .001 |
LV ejection fraction <50% | 37 (4.8) | 22 (3.0) | 15 (32.6) | < .001 |
LVOT gradient (mmHg) | 36 ± 40 18 [8–64] | 36 ± 40 10 [8–64] | 40 ± 46 10 [7–67] | .563 |
LVOT obstruction, n (%) | 305 (39.4) | 287 (39.4) | 18 (39.1) | .969 |
Moderate to severe MR, n (%) | 129 (16.7) | 118 (16.2) | 11 (23.9) | .174 |
Apical aneurysm | 6 (.8) | 5 (.7) | 1 (2.2) | .265 |
LGE presence, n (%) | 476 (61.5) | 433 (59.5) | 43 (93.5) | < .001 |
LGE (%) | 5.5 ± 7.1 3.8 [0–7.7] | 4.9 ± 6.6 3.2 [0–7.1] | 13.7 ± 9.4 10.4 [6.7–19.6] | < .001 |
0% ≤ LGE < 5% | 457 (59.0) | 452 (58.4) | 5 (10.9) | |
5%≤ LGE < 10% | 192 (24.8) | 175 (24.0) | 17 (37.0) | |
10% ≤ LGE < 15% | 59 (7.6) | 52 (7.1) | 7 (15.2) | |
LGE ≥ 15% | 66 (8.5) | 49 (6.7) | 17 (37.0) |
Values are represented as n (%), mean ± standard deviation, or median (inter-quartile range). Bold values indicate statistical significance.
LV, left ventricular; EDV, end-diastolic volume; ESV, end-systolic volume; LVOT, left ventricular outflow tract; MR, mitral regurgitation; LGE, late gadolinium enhancement.
. | All patients (n = 774) . | Patients without SCD end points (n = 728) . | Patients with SCD end points (n = 46) . | P-value . |
---|---|---|---|---|
Left atrial diameter (mm) | 39 ± 8 | 39 ± 8 | 44 ± 9 | < .001 |
LV end-diastolic diameter (mm) | 48 ± 6 | 48 ± 6 | 51 ± 11 | .020 |
Maximal wall thickness (mm) | 21 ± 6 | 21 ± 6 | 25 ± 7 | < .001 |
Maximal wall thickness ≥30 mm | 66 (8.5) | 59 (8.1) | 7 (15.2) | .094 |
LV mass index (g/m2) | 82.3 ± 36.6 | 80.8 ± 34.4 | 106.8 ± 56.3 | .003 |
LV EDV index (mL/m2) | 67.9 ± 20.2 | 66.8 ± 17.1 | 84.7 ± 44.5 | .009 |
LV ESV index (mL/m2) | 23.5 ± 15.7 | 22.4 ± 12.1 | 41.6 ± 39.0 | .002 |
Stroke volume (mL) | 79.8 ± 20.9 | 79.9 ± 20.3 | 78.2 ± 28.7 | .700 |
Cardiac index (L/min/m2) | 3.0 ± .9 | 3.0 ± .8 | 3.2 ± 1.4 | .493 |
LV ejection fraction (%) | 66.5 ± 9.7 | 67.1 ± 8.6 | 56.2 ± 17.3 | < .001 |
LV ejection fraction <50% | 37 (4.8) | 22 (3.0) | 15 (32.6) | < .001 |
LVOT gradient (mmHg) | 36 ± 40 18 [8–64] | 36 ± 40 10 [8–64] | 40 ± 46 10 [7–67] | .563 |
LVOT obstruction, n (%) | 305 (39.4) | 287 (39.4) | 18 (39.1) | .969 |
Moderate to severe MR, n (%) | 129 (16.7) | 118 (16.2) | 11 (23.9) | .174 |
Apical aneurysm | 6 (.8) | 5 (.7) | 1 (2.2) | .265 |
LGE presence, n (%) | 476 (61.5) | 433 (59.5) | 43 (93.5) | < .001 |
LGE (%) | 5.5 ± 7.1 3.8 [0–7.7] | 4.9 ± 6.6 3.2 [0–7.1] | 13.7 ± 9.4 10.4 [6.7–19.6] | < .001 |
0% ≤ LGE < 5% | 457 (59.0) | 452 (58.4) | 5 (10.9) | |
5%≤ LGE < 10% | 192 (24.8) | 175 (24.0) | 17 (37.0) | |
10% ≤ LGE < 15% | 59 (7.6) | 52 (7.1) | 7 (15.2) | |
LGE ≥ 15% | 66 (8.5) | 49 (6.7) | 17 (37.0) |
. | All patients (n = 774) . | Patients without SCD end points (n = 728) . | Patients with SCD end points (n = 46) . | P-value . |
---|---|---|---|---|
Left atrial diameter (mm) | 39 ± 8 | 39 ± 8 | 44 ± 9 | < .001 |
LV end-diastolic diameter (mm) | 48 ± 6 | 48 ± 6 | 51 ± 11 | .020 |
Maximal wall thickness (mm) | 21 ± 6 | 21 ± 6 | 25 ± 7 | < .001 |
Maximal wall thickness ≥30 mm | 66 (8.5) | 59 (8.1) | 7 (15.2) | .094 |
LV mass index (g/m2) | 82.3 ± 36.6 | 80.8 ± 34.4 | 106.8 ± 56.3 | .003 |
LV EDV index (mL/m2) | 67.9 ± 20.2 | 66.8 ± 17.1 | 84.7 ± 44.5 | .009 |
LV ESV index (mL/m2) | 23.5 ± 15.7 | 22.4 ± 12.1 | 41.6 ± 39.0 | .002 |
Stroke volume (mL) | 79.8 ± 20.9 | 79.9 ± 20.3 | 78.2 ± 28.7 | .700 |
Cardiac index (L/min/m2) | 3.0 ± .9 | 3.0 ± .8 | 3.2 ± 1.4 | .493 |
LV ejection fraction (%) | 66.5 ± 9.7 | 67.1 ± 8.6 | 56.2 ± 17.3 | < .001 |
LV ejection fraction <50% | 37 (4.8) | 22 (3.0) | 15 (32.6) | < .001 |
LVOT gradient (mmHg) | 36 ± 40 18 [8–64] | 36 ± 40 10 [8–64] | 40 ± 46 10 [7–67] | .563 |
LVOT obstruction, n (%) | 305 (39.4) | 287 (39.4) | 18 (39.1) | .969 |
Moderate to severe MR, n (%) | 129 (16.7) | 118 (16.2) | 11 (23.9) | .174 |
Apical aneurysm | 6 (.8) | 5 (.7) | 1 (2.2) | .265 |
LGE presence, n (%) | 476 (61.5) | 433 (59.5) | 43 (93.5) | < .001 |
LGE (%) | 5.5 ± 7.1 3.8 [0–7.7] | 4.9 ± 6.6 3.2 [0–7.1] | 13.7 ± 9.4 10.4 [6.7–19.6] | < .001 |
0% ≤ LGE < 5% | 457 (59.0) | 452 (58.4) | 5 (10.9) | |
5%≤ LGE < 10% | 192 (24.8) | 175 (24.0) | 17 (37.0) | |
10% ≤ LGE < 15% | 59 (7.6) | 52 (7.1) | 7 (15.2) | |
LGE ≥ 15% | 66 (8.5) | 49 (6.7) | 17 (37.0) |
Values are represented as n (%), mean ± standard deviation, or median (inter-quartile range). Bold values indicate statistical significance.
LV, left ventricular; EDV, end-diastolic volume; ESV, end-systolic volume; LVOT, left ventricular outflow tract; MR, mitral regurgitation; LGE, late gadolinium enhancement.
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