Geriatric Characteristics and Mortality According to Surgical Status of Left-Sided Infective Endocarditis for Older Patients Included in the MoISE study: 2013–2020
Characteristic . | All Patients (N = 163) . | Surgical Indication . | P Valueb . | No Surgical Indication (N = 58)a . | P Valuec . | |
---|---|---|---|---|---|---|
Operated On (N = 38)a . | Not Operated On (N = 67)a . | |||||
Usual place of residence | .02 | .02 | ||||
Home without nurse intervention | 127 (79) | 37/38 (97) | 51/65 (78) | 39/58 (67) | ||
Home with nurse intervention | 29 (18) | 1/38 (2.6) | 11/65 (17) | 17/58 (29) | ||
Nursing home | 5 (3.1) | 0/38 (0) | 3/65 (4.6) | 2/58 (3.4) | ||
Missing | 2 | 0/38 | 2/67 | 0/58 | ||
At admission | ||||||
Able to walk unassistedd | 81 (51) | 29/38 (76) | 23/65 (35) | <.001 | 29/56 (52) | .9 |
Activities of daily living score at admissiond | 4 (2–6) | 5 (4–6) | 3 (1–5.5) | .001 | 4 (2–6) | .6 |
Number of medicationsd | 7 (4–8) | 6 (3–8) | 6 (4–8) | .6 | 7 (5–10) | .03 |
Body mass index, kg/m2 | 24.6 (23.3–29.5) | 24.9 (22.5–27.4) | 24.3 (22.8–28.3) | .7 | 24.6 (22.9–27.4) | .9 |
In-hospital death | 51 (31) | 4/38 (11) | 37/67 (55) | <.001 | 10/58 (17) | .004 |
Among those alive at hospital discharge | ||||||
Able to walk unassistedd | 72/110 (65) | 30/34 (88) | 13/28 (43) | <.001 | 29/48 (63) | .7 |
Number of medicationsd | 8 (6–10) | 8 (7–9) | 8 (6–11) | .7 | 8 (6–12) | .7 |
Place of residence | .09 | |||||
Home with same support | 68/107 (64) | 31/34 (91) | 11/28 (39) | <.001 | 26/45 (58) | |
Home with more nurse supporte | 30/107 (28) | 3/34 (8,8) | 15/28 (54) | 12/45 (27) | ||
Admission to nursing home | 9/107 (8.4) | 0/34 (0) | 2/28 (7,1) | 7/45 (16) | ||
Missing | 5 | 0/34 | 2/30 | 3/48 | ||
Death at 1 mo | 39 (24) | 1/38 (2,6) | 30/67 (45) | <.001 | 8/58 (14) | .02 |
Death at 3 mo | 54 (33) | 4/38 (11) | 37/67 (55) | <.001 | 13/58 (22) | .03 |
Death at 6 mo | 57 (35) | 4/38 (11) | 40/67 (60) | <.001 | 13/58 (22) | .02 |
Death at 12 mo | 66 (41) | 6/38 (16) | 44/67 (66) | <.001 | 16/58 (28) | .02 |
Characteristic . | All Patients (N = 163) . | Surgical Indication . | P Valueb . | No Surgical Indication (N = 58)a . | P Valuec . | |
---|---|---|---|---|---|---|
Operated On (N = 38)a . | Not Operated On (N = 67)a . | |||||
Usual place of residence | .02 | .02 | ||||
Home without nurse intervention | 127 (79) | 37/38 (97) | 51/65 (78) | 39/58 (67) | ||
Home with nurse intervention | 29 (18) | 1/38 (2.6) | 11/65 (17) | 17/58 (29) | ||
Nursing home | 5 (3.1) | 0/38 (0) | 3/65 (4.6) | 2/58 (3.4) | ||
Missing | 2 | 0/38 | 2/67 | 0/58 | ||
At admission | ||||||
Able to walk unassistedd | 81 (51) | 29/38 (76) | 23/65 (35) | <.001 | 29/56 (52) | .9 |
Activities of daily living score at admissiond | 4 (2–6) | 5 (4–6) | 3 (1–5.5) | .001 | 4 (2–6) | .6 |
Number of medicationsd | 7 (4–8) | 6 (3–8) | 6 (4–8) | .6 | 7 (5–10) | .03 |
Body mass index, kg/m2 | 24.6 (23.3–29.5) | 24.9 (22.5–27.4) | 24.3 (22.8–28.3) | .7 | 24.6 (22.9–27.4) | .9 |
In-hospital death | 51 (31) | 4/38 (11) | 37/67 (55) | <.001 | 10/58 (17) | .004 |
Among those alive at hospital discharge | ||||||
Able to walk unassistedd | 72/110 (65) | 30/34 (88) | 13/28 (43) | <.001 | 29/48 (63) | .7 |
Number of medicationsd | 8 (6–10) | 8 (7–9) | 8 (6–11) | .7 | 8 (6–12) | .7 |
Place of residence | .09 | |||||
Home with same support | 68/107 (64) | 31/34 (91) | 11/28 (39) | <.001 | 26/45 (58) | |
Home with more nurse supporte | 30/107 (28) | 3/34 (8,8) | 15/28 (54) | 12/45 (27) | ||
Admission to nursing home | 9/107 (8.4) | 0/34 (0) | 2/28 (7,1) | 7/45 (16) | ||
Missing | 5 | 0/34 | 2/30 | 3/48 | ||
Death at 1 mo | 39 (24) | 1/38 (2,6) | 30/67 (45) | <.001 | 8/58 (14) | .02 |
Death at 3 mo | 54 (33) | 4/38 (11) | 37/67 (55) | <.001 | 13/58 (22) | .03 |
Death at 6 mo | 57 (35) | 4/38 (11) | 40/67 (60) | <.001 | 13/58 (22) | .02 |
Death at 12 mo | 66 (41) | 6/38 (16) | 44/67 (66) | <.001 | 16/58 (28) | .02 |
aN (%), median (IQR).
bPearson χ2 test or Fisher exact test between patients with surgical indication operated or not.
cSame tests between patients with and without surgical indication.
dData missing for ability to walk/activities of daily living score (n = 4), number of medications (n = 2), and body mass index (n = 30) at admission and for ability to walk (n = 2) and number of medications (n = 2) at discharge.
eExcluding nurse for outpatient parenteral antibiotic therapy only.
Geriatric Characteristics and Mortality According to Surgical Status of Left-Sided Infective Endocarditis for Older Patients Included in the MoISE study: 2013–2020
Characteristic . | All Patients (N = 163) . | Surgical Indication . | P Valueb . | No Surgical Indication (N = 58)a . | P Valuec . | |
---|---|---|---|---|---|---|
Operated On (N = 38)a . | Not Operated On (N = 67)a . | |||||
Usual place of residence | .02 | .02 | ||||
Home without nurse intervention | 127 (79) | 37/38 (97) | 51/65 (78) | 39/58 (67) | ||
Home with nurse intervention | 29 (18) | 1/38 (2.6) | 11/65 (17) | 17/58 (29) | ||
Nursing home | 5 (3.1) | 0/38 (0) | 3/65 (4.6) | 2/58 (3.4) | ||
Missing | 2 | 0/38 | 2/67 | 0/58 | ||
At admission | ||||||
Able to walk unassistedd | 81 (51) | 29/38 (76) | 23/65 (35) | <.001 | 29/56 (52) | .9 |
Activities of daily living score at admissiond | 4 (2–6) | 5 (4–6) | 3 (1–5.5) | .001 | 4 (2–6) | .6 |
Number of medicationsd | 7 (4–8) | 6 (3–8) | 6 (4–8) | .6 | 7 (5–10) | .03 |
Body mass index, kg/m2 | 24.6 (23.3–29.5) | 24.9 (22.5–27.4) | 24.3 (22.8–28.3) | .7 | 24.6 (22.9–27.4) | .9 |
In-hospital death | 51 (31) | 4/38 (11) | 37/67 (55) | <.001 | 10/58 (17) | .004 |
Among those alive at hospital discharge | ||||||
Able to walk unassistedd | 72/110 (65) | 30/34 (88) | 13/28 (43) | <.001 | 29/48 (63) | .7 |
Number of medicationsd | 8 (6–10) | 8 (7–9) | 8 (6–11) | .7 | 8 (6–12) | .7 |
Place of residence | .09 | |||||
Home with same support | 68/107 (64) | 31/34 (91) | 11/28 (39) | <.001 | 26/45 (58) | |
Home with more nurse supporte | 30/107 (28) | 3/34 (8,8) | 15/28 (54) | 12/45 (27) | ||
Admission to nursing home | 9/107 (8.4) | 0/34 (0) | 2/28 (7,1) | 7/45 (16) | ||
Missing | 5 | 0/34 | 2/30 | 3/48 | ||
Death at 1 mo | 39 (24) | 1/38 (2,6) | 30/67 (45) | <.001 | 8/58 (14) | .02 |
Death at 3 mo | 54 (33) | 4/38 (11) | 37/67 (55) | <.001 | 13/58 (22) | .03 |
Death at 6 mo | 57 (35) | 4/38 (11) | 40/67 (60) | <.001 | 13/58 (22) | .02 |
Death at 12 mo | 66 (41) | 6/38 (16) | 44/67 (66) | <.001 | 16/58 (28) | .02 |
Characteristic . | All Patients (N = 163) . | Surgical Indication . | P Valueb . | No Surgical Indication (N = 58)a . | P Valuec . | |
---|---|---|---|---|---|---|
Operated On (N = 38)a . | Not Operated On (N = 67)a . | |||||
Usual place of residence | .02 | .02 | ||||
Home without nurse intervention | 127 (79) | 37/38 (97) | 51/65 (78) | 39/58 (67) | ||
Home with nurse intervention | 29 (18) | 1/38 (2.6) | 11/65 (17) | 17/58 (29) | ||
Nursing home | 5 (3.1) | 0/38 (0) | 3/65 (4.6) | 2/58 (3.4) | ||
Missing | 2 | 0/38 | 2/67 | 0/58 | ||
At admission | ||||||
Able to walk unassistedd | 81 (51) | 29/38 (76) | 23/65 (35) | <.001 | 29/56 (52) | .9 |
Activities of daily living score at admissiond | 4 (2–6) | 5 (4–6) | 3 (1–5.5) | .001 | 4 (2–6) | .6 |
Number of medicationsd | 7 (4–8) | 6 (3–8) | 6 (4–8) | .6 | 7 (5–10) | .03 |
Body mass index, kg/m2 | 24.6 (23.3–29.5) | 24.9 (22.5–27.4) | 24.3 (22.8–28.3) | .7 | 24.6 (22.9–27.4) | .9 |
In-hospital death | 51 (31) | 4/38 (11) | 37/67 (55) | <.001 | 10/58 (17) | .004 |
Among those alive at hospital discharge | ||||||
Able to walk unassistedd | 72/110 (65) | 30/34 (88) | 13/28 (43) | <.001 | 29/48 (63) | .7 |
Number of medicationsd | 8 (6–10) | 8 (7–9) | 8 (6–11) | .7 | 8 (6–12) | .7 |
Place of residence | .09 | |||||
Home with same support | 68/107 (64) | 31/34 (91) | 11/28 (39) | <.001 | 26/45 (58) | |
Home with more nurse supporte | 30/107 (28) | 3/34 (8,8) | 15/28 (54) | 12/45 (27) | ||
Admission to nursing home | 9/107 (8.4) | 0/34 (0) | 2/28 (7,1) | 7/45 (16) | ||
Missing | 5 | 0/34 | 2/30 | 3/48 | ||
Death at 1 mo | 39 (24) | 1/38 (2,6) | 30/67 (45) | <.001 | 8/58 (14) | .02 |
Death at 3 mo | 54 (33) | 4/38 (11) | 37/67 (55) | <.001 | 13/58 (22) | .03 |
Death at 6 mo | 57 (35) | 4/38 (11) | 40/67 (60) | <.001 | 13/58 (22) | .02 |
Death at 12 mo | 66 (41) | 6/38 (16) | 44/67 (66) | <.001 | 16/58 (28) | .02 |
aN (%), median (IQR).
bPearson χ2 test or Fisher exact test between patients with surgical indication operated or not.
cSame tests between patients with and without surgical indication.
dData missing for ability to walk/activities of daily living score (n = 4), number of medications (n = 2), and body mass index (n = 30) at admission and for ability to walk (n = 2) and number of medications (n = 2) at discharge.
eExcluding nurse for outpatient parenteral antibiotic therapy only.
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