Table 2.

Statistical analysis of antimicrobial percentage susceptibility (%S) in S. pneumoniae

CLSI %S
Antimicrobial2002–032004–052007–09P valueConclusion
Penicillin (oral)74.767.847.2<0.0001significant decrease in susceptibility
Amoxicillin/clavulanic acid100.098.797.70.116non-significant change in susceptibility
Cefaclor85.378.753.5<0.0001significant decrease in susceptibility
Clarithromycina85.382.761.9<0.0001significant decrease in susceptibility
CLSI %S
Antimicrobial2002–032004–052007–09P valueConclusion
Penicillin (oral)74.767.847.2<0.0001significant decrease in susceptibility
Amoxicillin/clavulanic acid100.098.797.70.116non-significant change in susceptibility
Cefaclor85.378.753.5<0.0001significant decrease in susceptibility
Clarithromycina85.382.761.9<0.0001significant decrease in susceptibility

aClarithromycin data in 2002–03 from Etests incubated in 5% CO2 and ambient atmosphere in 2004–05 and 2007–09, with differing associated breakpoints used as shown in Table 1.

Table 2.

Statistical analysis of antimicrobial percentage susceptibility (%S) in S. pneumoniae

CLSI %S
Antimicrobial2002–032004–052007–09P valueConclusion
Penicillin (oral)74.767.847.2<0.0001significant decrease in susceptibility
Amoxicillin/clavulanic acid100.098.797.70.116non-significant change in susceptibility
Cefaclor85.378.753.5<0.0001significant decrease in susceptibility
Clarithromycina85.382.761.9<0.0001significant decrease in susceptibility
CLSI %S
Antimicrobial2002–032004–052007–09P valueConclusion
Penicillin (oral)74.767.847.2<0.0001significant decrease in susceptibility
Amoxicillin/clavulanic acid100.098.797.70.116non-significant change in susceptibility
Cefaclor85.378.753.5<0.0001significant decrease in susceptibility
Clarithromycina85.382.761.9<0.0001significant decrease in susceptibility

aClarithromycin data in 2002–03 from Etests incubated in 5% CO2 and ambient atmosphere in 2004–05 and 2007–09, with differing associated breakpoints used as shown in Table 1.

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