Table 2

TOE vs. CT vs. CMR vs. 3D Echo12–39

ModalityAdvantagesDisadvantages
CT1. Aid identification of paravalvular pathology1. Radiation exposure and not usable in patients with iodine allergy
2. Detailed assessment of valve thickness, calcification, and annular fibrosis
3. For pre-operative evaluation before mitral valve repair and can help predict clinical outcomes
4. CT may be preferable to echo for follow-up imaging after mitral valve repair due to enhanced special resolution and reduced interference from metal artefact
5. Useful in patients with poor echo windows
6. Can identify insufficient coaptation of aortic valve leaflets and pathognomonic central regurgitation
CMR1. Beneficial in assessing the impact of RHD on cardiac function and can be utilized to determine the aetiology of left ventricular dysfunction and aid quantification of regurgitant volumes1. Concurrent cardiac arrhythmias may impact image quality and MR assessment on CMRI
2. CMRI may be utilized in the assessment of MS severity with planimetric MVA measurements2. Expensive modality and not widely available
3. CMRI can demonstrate favourable cardiac remodelling following balloon mitral valvuloplasty
4. CMRI to accurately estimate LV myocardial fibrosis may also be used in the prognostic assessment of morbidity in RHD patients following surgery
5. CMRI allows for detailed assessment and evaluation of regurgitant valves without systematic overestimating
6. Advantage of CMRI over echocardiography is the capability to calculate MR severity regardless of the regurgitant jet shape or direction
Three-dimensional Echocardiography1. More accurate than conventional 2D imaging at assessing suitability for valve surgery1. Expensive
2. Used to assess TR severity and progression pre- and post-mitral valve replacement2. Requires special training
3. The 3D TOE can help clarify the MVA by planimetry where transthoracic images are suboptimal
4. Post-surgical right ventricle assessment is more accurate
TOE1. Can help clarify disease mechanisms or severity where this is unclear1. Uncomfortable for patients not under anaesthetic
2. Helps aid intervention planning including excluding left atrial appendage thrombus prior to percutaneous balloon mitral valvuloplasty in patients with rheumatic mitral stenosis and clarifying suitability for valve repair or replacement2. Not repeatable for regular follow-up
3. TOE has also been used to look at results post for paravalvular leak3. Expensive
4. Useful for evaluation during surgery and is especially useful for minimally invasive surgery
ModalityAdvantagesDisadvantages
CT1. Aid identification of paravalvular pathology1. Radiation exposure and not usable in patients with iodine allergy
2. Detailed assessment of valve thickness, calcification, and annular fibrosis
3. For pre-operative evaluation before mitral valve repair and can help predict clinical outcomes
4. CT may be preferable to echo for follow-up imaging after mitral valve repair due to enhanced special resolution and reduced interference from metal artefact
5. Useful in patients with poor echo windows
6. Can identify insufficient coaptation of aortic valve leaflets and pathognomonic central regurgitation
CMR1. Beneficial in assessing the impact of RHD on cardiac function and can be utilized to determine the aetiology of left ventricular dysfunction and aid quantification of regurgitant volumes1. Concurrent cardiac arrhythmias may impact image quality and MR assessment on CMRI
2. CMRI may be utilized in the assessment of MS severity with planimetric MVA measurements2. Expensive modality and not widely available
3. CMRI can demonstrate favourable cardiac remodelling following balloon mitral valvuloplasty
4. CMRI to accurately estimate LV myocardial fibrosis may also be used in the prognostic assessment of morbidity in RHD patients following surgery
5. CMRI allows for detailed assessment and evaluation of regurgitant valves without systematic overestimating
6. Advantage of CMRI over echocardiography is the capability to calculate MR severity regardless of the regurgitant jet shape or direction
Three-dimensional Echocardiography1. More accurate than conventional 2D imaging at assessing suitability for valve surgery1. Expensive
2. Used to assess TR severity and progression pre- and post-mitral valve replacement2. Requires special training
3. The 3D TOE can help clarify the MVA by planimetry where transthoracic images are suboptimal
4. Post-surgical right ventricle assessment is more accurate
TOE1. Can help clarify disease mechanisms or severity where this is unclear1. Uncomfortable for patients not under anaesthetic
2. Helps aid intervention planning including excluding left atrial appendage thrombus prior to percutaneous balloon mitral valvuloplasty in patients with rheumatic mitral stenosis and clarifying suitability for valve repair or replacement2. Not repeatable for regular follow-up
3. TOE has also been used to look at results post for paravalvular leak3. Expensive
4. Useful for evaluation during surgery and is especially useful for minimally invasive surgery

CMR, cardiac magnetic resonance; CMRI, cardiac magnetic resonance imaging; CT, computed tomography; MR, mitral regurgitation; MS, mitral stenosis; MVA, mitral valve area; RHD, rheumatic heart disease; TOE, transoesophageal echocardiography; TR, tricuspid regurgitation.

Table 2

TOE vs. CT vs. CMR vs. 3D Echo12–39

ModalityAdvantagesDisadvantages
CT1. Aid identification of paravalvular pathology1. Radiation exposure and not usable in patients with iodine allergy
2. Detailed assessment of valve thickness, calcification, and annular fibrosis
3. For pre-operative evaluation before mitral valve repair and can help predict clinical outcomes
4. CT may be preferable to echo for follow-up imaging after mitral valve repair due to enhanced special resolution and reduced interference from metal artefact
5. Useful in patients with poor echo windows
6. Can identify insufficient coaptation of aortic valve leaflets and pathognomonic central regurgitation
CMR1. Beneficial in assessing the impact of RHD on cardiac function and can be utilized to determine the aetiology of left ventricular dysfunction and aid quantification of regurgitant volumes1. Concurrent cardiac arrhythmias may impact image quality and MR assessment on CMRI
2. CMRI may be utilized in the assessment of MS severity with planimetric MVA measurements2. Expensive modality and not widely available
3. CMRI can demonstrate favourable cardiac remodelling following balloon mitral valvuloplasty
4. CMRI to accurately estimate LV myocardial fibrosis may also be used in the prognostic assessment of morbidity in RHD patients following surgery
5. CMRI allows for detailed assessment and evaluation of regurgitant valves without systematic overestimating
6. Advantage of CMRI over echocardiography is the capability to calculate MR severity regardless of the regurgitant jet shape or direction
Three-dimensional Echocardiography1. More accurate than conventional 2D imaging at assessing suitability for valve surgery1. Expensive
2. Used to assess TR severity and progression pre- and post-mitral valve replacement2. Requires special training
3. The 3D TOE can help clarify the MVA by planimetry where transthoracic images are suboptimal
4. Post-surgical right ventricle assessment is more accurate
TOE1. Can help clarify disease mechanisms or severity where this is unclear1. Uncomfortable for patients not under anaesthetic
2. Helps aid intervention planning including excluding left atrial appendage thrombus prior to percutaneous balloon mitral valvuloplasty in patients with rheumatic mitral stenosis and clarifying suitability for valve repair or replacement2. Not repeatable for regular follow-up
3. TOE has also been used to look at results post for paravalvular leak3. Expensive
4. Useful for evaluation during surgery and is especially useful for minimally invasive surgery
ModalityAdvantagesDisadvantages
CT1. Aid identification of paravalvular pathology1. Radiation exposure and not usable in patients with iodine allergy
2. Detailed assessment of valve thickness, calcification, and annular fibrosis
3. For pre-operative evaluation before mitral valve repair and can help predict clinical outcomes
4. CT may be preferable to echo for follow-up imaging after mitral valve repair due to enhanced special resolution and reduced interference from metal artefact
5. Useful in patients with poor echo windows
6. Can identify insufficient coaptation of aortic valve leaflets and pathognomonic central regurgitation
CMR1. Beneficial in assessing the impact of RHD on cardiac function and can be utilized to determine the aetiology of left ventricular dysfunction and aid quantification of regurgitant volumes1. Concurrent cardiac arrhythmias may impact image quality and MR assessment on CMRI
2. CMRI may be utilized in the assessment of MS severity with planimetric MVA measurements2. Expensive modality and not widely available
3. CMRI can demonstrate favourable cardiac remodelling following balloon mitral valvuloplasty
4. CMRI to accurately estimate LV myocardial fibrosis may also be used in the prognostic assessment of morbidity in RHD patients following surgery
5. CMRI allows for detailed assessment and evaluation of regurgitant valves without systematic overestimating
6. Advantage of CMRI over echocardiography is the capability to calculate MR severity regardless of the regurgitant jet shape or direction
Three-dimensional Echocardiography1. More accurate than conventional 2D imaging at assessing suitability for valve surgery1. Expensive
2. Used to assess TR severity and progression pre- and post-mitral valve replacement2. Requires special training
3. The 3D TOE can help clarify the MVA by planimetry where transthoracic images are suboptimal
4. Post-surgical right ventricle assessment is more accurate
TOE1. Can help clarify disease mechanisms or severity where this is unclear1. Uncomfortable for patients not under anaesthetic
2. Helps aid intervention planning including excluding left atrial appendage thrombus prior to percutaneous balloon mitral valvuloplasty in patients with rheumatic mitral stenosis and clarifying suitability for valve repair or replacement2. Not repeatable for regular follow-up
3. TOE has also been used to look at results post for paravalvular leak3. Expensive
4. Useful for evaluation during surgery and is especially useful for minimally invasive surgery

CMR, cardiac magnetic resonance; CMRI, cardiac magnetic resonance imaging; CT, computed tomography; MR, mitral regurgitation; MS, mitral stenosis; MVA, mitral valve area; RHD, rheumatic heart disease; TOE, transoesophageal echocardiography; TR, tricuspid regurgitation.

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