Table 3 Open in new tab Cox proportional...

	Model 1^a	Model 2^b	Model 3^c	Model 4^d
Natural FMP
Black	1.09	0.97–1.22	0.131	1.05	0.94–1.18	0.367	1.11	1.01–1.21	0.023	1.15	1.04–1.27	0.008
Chinese	1.08	0.92–1.28	0.336	1.04	0.88–1.23	0.634	1.03	0.89–1.17	0.342	1.02	0.87–1.16	0.411
Hispanic	1.27	1.03–1.57	0.026	1.25	1.01–1.54	0.037	1.19	1.04–1.34	0.012	1.18	0.97–1.38	0.062
Japanese	1.02	0.88–1.19	0.793	0.95	0.81–1.11	0.498	0.97	0.83–1.10	0.690	0.97	0.83–1.10	0.683
Surgical FMP
White				1.25	1.03–1.52	0.025	1.34	1.15–1.53	0.002	1.58	1.24–1.93	0.005
Black				2.59	2.10–3.19	0.000	2.41	2.20–2.63	0.000	3.02	2.58–3.45	0.000
Chinese^e				0.94	0.52–1.70	0.827	0.97	0.39–1.55	0.542	1.57	0.71–2.43	0.151
Hispanic^e				1.83	1.10–3.06	0.021	2.07	1.60–2.55	0.001	2.63	2.02–3.23	0.001
Japanese^e				1.88	1.11–3.20	0.019	1.27	0.77–1.77	0.176	1.43	0.99–1.87	0.055

Model 1^a

Model 2^b

Model 3^c

Model 4^d

Unadjusted for selection (n_events = 1804)

Incorporating FMP type (n_events = 2059)

+ Imputed for right censoring (n_events = 3302)

+ Adjusted for left truncation (n_events = 3302)

Racial group × FMP type (ref: White, natural FMP)

Hazard ratio

95% CI

Hazard ratio

95% CI

Hazard ratio

95% CI

Hazard ratio

95% CI

Natural FMP

Black

1.09

0.97–1.22

0.131

1.05

0.94–1.18

0.367

1.11

1.01–1.21

0.023

1.15

1.04–1.27

0.008

Chinese

1.08

0.92–1.28

0.336

1.04

0.88–1.23

0.634

1.03

0.89–1.17

0.342

1.02

0.87–1.16

0.411

Hispanic

1.27

1.03–1.57

0.026

1.25

1.01–1.54

0.037

1.19

1.04–1.34

0.012

1.18

0.97–1.38

0.062

Japanese

1.02

0.88–1.19

0.793

0.95

0.81–1.11

0.498

0.97

0.83–1.10

0.690

0.97

0.83–1.10

0.683

Surgical FMP

White

1.25

1.03–1.52

0.025

1.34

1.15–1.53

0.002

1.58

1.24–1.93

0.005

Black

2.59

2.10–3.19

0.000

2.41

2.20–2.63

0.000

3.02

2.58–3.45

0.000

Chinese^e

0.94

0.52–1.70

0.827

0.97

0.39–1.55

0.542

1.57

0.71–2.43

0.151

Hispanic^e

1.83

1.10–3.06

0.021

2.07

1.60–2.55

0.001

2.63

2.02–3.23

0.001

Japanese^e

1.88

1.11–3.20

0.019

1.27

0.77–1.77

0.176

1.43

0.99–1.87

0.055

	Model 1^a	Model 2^b	Model 3^c	Model 4^d
Natural FMP
Black	1.09	0.97–1.22	0.131	1.05	0.94–1.18	0.367	1.11	1.01–1.21	0.023	1.15	1.04–1.27	0.008
Chinese	1.08	0.92–1.28	0.336	1.04	0.88–1.23	0.634	1.03	0.89–1.17	0.342	1.02	0.87–1.16	0.411
Hispanic	1.27	1.03–1.57	0.026	1.25	1.01–1.54	0.037	1.19	1.04–1.34	0.012	1.18	0.97–1.38	0.062
Japanese	1.02	0.88–1.19	0.793	0.95	0.81–1.11	0.498	0.97	0.83–1.10	0.690	0.97	0.83–1.10	0.683
Surgical FMP
White				1.25	1.03–1.52	0.025	1.34	1.15–1.53	0.002	1.58	1.24–1.93	0.005
Black				2.59	2.10–3.19	0.000	2.41	2.20–2.63	0.000	3.02	2.58–3.45	0.000
Chinese^e				0.94	0.52–1.70	0.827	0.97	0.39–1.55	0.542	1.57	0.71–2.43	0.151
Hispanic^e				1.83	1.10–3.06	0.021	2.07	1.60–2.55	0.001	2.63	2.02–3.23	0.001
Japanese^e				1.88	1.11–3.20	0.019	1.27	0.77–1.77	0.176	1.43	0.99–1.87	0.055

Table 3

Open in new tab

Cox proportional hazard models for age at final menstrual period (FMP) accounting for successive selection mechanisms

	Model 1^a			Model 2^b			Model 3^c			Model 4^d
	Unadjusted for selection (n_events = 1804)			Incorporating FMP type (n_events = 2059)			+ Imputed for right censoring (n_events = 3302)			+ Adjusted for left truncation (n_events = 3302)
Racial group × FMP type (ref: White, natural FMP)	Hazard ratio	95% CI	P	Hazard ratio	95% CI	P	Hazard ratio	95% CI	P	Hazard ratio	95% CI	P
Natural FMP
Black	1.09	0.97–1.22	0.131	1.05	0.94–1.18	0.367	1.11	1.01–1.21	0.023	1.15	1.04–1.27	0.008
Chinese	1.08	0.92–1.28	0.336	1.04	0.88–1.23	0.634	1.03	0.89–1.17	0.342	1.02	0.87–1.16	0.411
Hispanic	1.27	1.03–1.57	0.026	1.25	1.01–1.54	0.037	1.19	1.04–1.34	0.012	1.18	0.97–1.38	0.062
Japanese	1.02	0.88–1.19	0.793	0.95	0.81–1.11	0.498	0.97	0.83–1.10	0.690	0.97	0.83–1.10	0.683
Surgical FMP
White				1.25	1.03–1.52	0.025	1.34	1.15–1.53	0.002	1.58	1.24–1.93	0.005
Black				2.59	2.10–3.19	0.000	2.41	2.20–2.63	0.000	3.02	2.58–3.45	0.000
Chinese^e				0.94	0.52–1.70	0.827	0.97	0.39–1.55	0.542	1.57	0.71–2.43	0.151
Hispanic^e				1.83	1.10–3.06	0.021	2.07	1.60–2.55	0.001	2.63	2.02–3.23	0.001
Japanese^e				1.88	1.11–3.20	0.019	1.27	0.77–1.77	0.176	1.43	0.99–1.87	0.055

	Model 1^a			Model 2^b			Model 3^c			Model 4^d
	Unadjusted for selection (n_events = 1804)			Incorporating FMP type (n_events = 2059)			+ Imputed for right censoring (n_events = 3302)			+ Adjusted for left truncation (n_events = 3302)
Racial group × FMP type (ref: White, natural FMP)	Hazard ratio	95% CI	P	Hazard ratio	95% CI	P	Hazard ratio	95% CI	P	Hazard ratio	95% CI	P
Natural FMP
Black	1.09	0.97–1.22	0.131	1.05	0.94–1.18	0.367	1.11	1.01–1.21	0.023	1.15	1.04–1.27	0.008
Chinese	1.08	0.92–1.28	0.336	1.04	0.88–1.23	0.634	1.03	0.89–1.17	0.342	1.02	0.87–1.16	0.411
Hispanic	1.27	1.03–1.57	0.026	1.25	1.01–1.54	0.037	1.19	1.04–1.34	0.012	1.18	0.97–1.38	0.062
Japanese	1.02	0.88–1.19	0.793	0.95	0.81–1.11	0.498	0.97	0.83–1.10	0.690	0.97	0.83–1.10	0.683
Surgical FMP
White				1.25	1.03–1.52	0.025	1.34	1.15–1.53	0.002	1.58	1.24–1.93	0.005
Black				2.59	2.10–3.19	0.000	2.41	2.20–2.63	0.000	3.02	2.58–3.45	0.000
Chinese^e				0.94	0.52–1.70	0.827	0.97	0.39–1.55	0.542	1.57	0.71–2.43	0.151
Hispanic^e				1.83	1.10–3.06	0.021	2.07	1.60–2.55	0.001	2.63	2.02–3.23	0.001
Japanese^e				1.88	1.11–3.20	0.019	1.27	0.77–1.77	0.176	1.43	0.99–1.87	0.055

Each subsequent model has the ‘corrected’ features of the last with additional corrections, denoted by + sign.

Model 1: right censored for any missing FMPs and for observed surgical FMPs.

Model 2: only censors for unobserved FMPs and includes in observed surgical FMPs by incorporating an interaction term between racial/ethnic group and FMP type.

Model 3: additionally imputes data pooled across 10 imputed sets removing any right censoring on FMP.

Model 4: additionally incorporates inverse probability weights for left truncation.

Chinese (n = 13), Hispanic (n = 39), Japanese (n = 16), all other groups >90 observations.

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