Table 3.
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Risk factors associated with conversion to dementia during follow-up.

nHR Conversion (95% CI)PP adjusted (age, sex, ApoE, education)
Age3601.04 (1.01–1.08)0.02070.0020
Sex3600.90 (0.63–1.31)0.59150.2169
BMI3540.99 (0.94–1.04)0.65170.6490
MMSE3540.85 (0.80–0.90)<0.0001<0.0001
APOE43582.57 (1.79–3.68)<0.0001<0.0001
Hippocampal volume2770.50 (0.42–0.60)<0.0001<0.0001
Educational level3590.96 (0.86–1.08)0.48170.6675
Lumipulse pTau1813601.30 (1.21–1.40)<0.0001<0.0001
Simoa pTau1813601.39 (1.26–1.54)<0.0001<0.0001
nHR Conversion (95% CI)PP adjusted (age, sex, ApoE, education)
Age3601.04 (1.01–1.08)0.02070.0020
Sex3600.90 (0.63–1.31)0.59150.2169
BMI3540.99 (0.94–1.04)0.65170.6490
MMSE3540.85 (0.80–0.90)<0.0001<0.0001
APOE43582.57 (1.79–3.68)<0.0001<0.0001
Hippocampal volume2770.50 (0.42–0.60)<0.0001<0.0001
Educational level3590.96 (0.86–1.08)0.48170.6675
Lumipulse pTau1813601.30 (1.21–1.40)<0.0001<0.0001
Simoa pTau1813601.39 (1.26–1.54)<0.0001<0.0001

Cox proportional hazard model of conversion to dementia in follow-up before and after adjustment for age, sex, educational level, and the APOEε4 status.

Abbreviations: HR, hazard ratio for conversion; BMI, body mass index.

Statistically significant P values are shown in bold.

Table 3.
Open in new tab

Risk factors associated with conversion to dementia during follow-up.

nHR Conversion (95% CI)PP adjusted (age, sex, ApoE, education)
Age3601.04 (1.01–1.08)0.02070.0020
Sex3600.90 (0.63–1.31)0.59150.2169
BMI3540.99 (0.94–1.04)0.65170.6490
MMSE3540.85 (0.80–0.90)<0.0001<0.0001
APOE43582.57 (1.79–3.68)<0.0001<0.0001
Hippocampal volume2770.50 (0.42–0.60)<0.0001<0.0001
Educational level3590.96 (0.86–1.08)0.48170.6675
Lumipulse pTau1813601.30 (1.21–1.40)<0.0001<0.0001
Simoa pTau1813601.39 (1.26–1.54)<0.0001<0.0001
nHR Conversion (95% CI)PP adjusted (age, sex, ApoE, education)
Age3601.04 (1.01–1.08)0.02070.0020
Sex3600.90 (0.63–1.31)0.59150.2169
BMI3540.99 (0.94–1.04)0.65170.6490
MMSE3540.85 (0.80–0.90)<0.0001<0.0001
APOE43582.57 (1.79–3.68)<0.0001<0.0001
Hippocampal volume2770.50 (0.42–0.60)<0.0001<0.0001
Educational level3590.96 (0.86–1.08)0.48170.6675
Lumipulse pTau1813601.30 (1.21–1.40)<0.0001<0.0001
Simoa pTau1813601.39 (1.26–1.54)<0.0001<0.0001

Cox proportional hazard model of conversion to dementia in follow-up before and after adjustment for age, sex, educational level, and the APOEε4 status.

Abbreviations: HR, hazard ratio for conversion; BMI, body mass index.

Statistically significant P values are shown in bold.

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