Table 2:

Association between urinary selenium excretion and all-cause mortality in KTR.

Tertiles of urinary selenium excretiona
Tertile 1Tertile 2Tertile 3Urinary selenium excretion, log2
ModelsHR95% CIPHR95% CIPRefHR95% CIP
Crude2.361.70‒3.28<.0011.340.94‒1.91.11Ref0.550.44‒0.70<.001
Model 12.491.76‒3.54<.0011.350.94‒1.93.11Ref0.550.42‒0.71<.001
Model 22.121.45‒3.11<.0011.180.79‒1.75.41Ref0.630.48‒0.84.001
Model 32.181.52‒3.12<.0011.230.86‒1.77.26Ref0.620.48‒0.81<.001
Model 42.461.73‒3.49<.0011.360.94‒1.95.10Ref0.570.44‒0.73<.001
Model 52.471.74‒3.50<.0011.330.93‒1.91.12Ref0.550.43‒0.71<.001
Tertiles of urinary selenium excretiona
Tertile 1Tertile 2Tertile 3Urinary selenium excretion, log2
ModelsHR95% CIPHR95% CIPRefHR95% CIP
Crude2.361.70‒3.28<.0011.340.94‒1.91.11Ref0.550.44‒0.70<.001
Model 12.491.76‒3.54<.0011.350.94‒1.93.11Ref0.550.42‒0.71<.001
Model 22.121.45‒3.11<.0011.180.79‒1.75.41Ref0.630.48‒0.84.001
Model 32.181.52‒3.12<.0011.230.86‒1.77.26Ref0.620.48‒0.81<.001
Model 42.461.73‒3.49<.0011.360.94‒1.95.10Ref0.570.44‒0.73<.001
Model 52.471.74‒3.50<.0011.330.93‒1.91.12Ref0.550.43‒0.71<.001
a

Tertile 1: <16.4 μg/24-h; tertile 2: 16.4‒21.6 μg/24-h; tertile 3: >21.6 μg/24-h. In total, 229 (33%) KTR died (tertile 1: 107, tertile 2: 68, tertile 3: 54). Model 1: adjustment for age, sex and body surface area. Model 2: Model 1 + plasma albumin concentration, and protein, bread, fruit, vegetable and bread intake. Model 3: Model 1 + proteinuria, eGFR and urinary volume. Model 4: Model 1 + pre-emptive transplantation, living donor and time since transplantation. Model 5: Model 1 + calcineurin inhibitor usage, proliferation inhibitor usage and acute rejection treatment.

Table 2:

Association between urinary selenium excretion and all-cause mortality in KTR.

Tertiles of urinary selenium excretiona
Tertile 1Tertile 2Tertile 3Urinary selenium excretion, log2
ModelsHR95% CIPHR95% CIPRefHR95% CIP
Crude2.361.70‒3.28<.0011.340.94‒1.91.11Ref0.550.44‒0.70<.001
Model 12.491.76‒3.54<.0011.350.94‒1.93.11Ref0.550.42‒0.71<.001
Model 22.121.45‒3.11<.0011.180.79‒1.75.41Ref0.630.48‒0.84.001
Model 32.181.52‒3.12<.0011.230.86‒1.77.26Ref0.620.48‒0.81<.001
Model 42.461.73‒3.49<.0011.360.94‒1.95.10Ref0.570.44‒0.73<.001
Model 52.471.74‒3.50<.0011.330.93‒1.91.12Ref0.550.43‒0.71<.001
Tertiles of urinary selenium excretiona
Tertile 1Tertile 2Tertile 3Urinary selenium excretion, log2
ModelsHR95% CIPHR95% CIPRefHR95% CIP
Crude2.361.70‒3.28<.0011.340.94‒1.91.11Ref0.550.44‒0.70<.001
Model 12.491.76‒3.54<.0011.350.94‒1.93.11Ref0.550.42‒0.71<.001
Model 22.121.45‒3.11<.0011.180.79‒1.75.41Ref0.630.48‒0.84.001
Model 32.181.52‒3.12<.0011.230.86‒1.77.26Ref0.620.48‒0.81<.001
Model 42.461.73‒3.49<.0011.360.94‒1.95.10Ref0.570.44‒0.73<.001
Model 52.471.74‒3.50<.0011.330.93‒1.91.12Ref0.550.43‒0.71<.001
a

Tertile 1: <16.4 μg/24-h; tertile 2: 16.4‒21.6 μg/24-h; tertile 3: >21.6 μg/24-h. In total, 229 (33%) KTR died (tertile 1: 107, tertile 2: 68, tertile 3: 54). Model 1: adjustment for age, sex and body surface area. Model 2: Model 1 + plasma albumin concentration, and protein, bread, fruit, vegetable and bread intake. Model 3: Model 1 + proteinuria, eGFR and urinary volume. Model 4: Model 1 + pre-emptive transplantation, living donor and time since transplantation. Model 5: Model 1 + calcineurin inhibitor usage, proliferation inhibitor usage and acute rejection treatment.

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