Table 3.

Risk Factors Associated With Infectious Disease Syndromes Impacting Daily Activities

ID Syndrome Impacting Daily Activities (n = 471)Univariate OR (95% CI)Multivariate OR (95% CI)P Value
Age, y4711.01 (0.99–1.02)
Male gender4111.1 (0.8–1.5)
Race
 Caucasian (ref)386
 Black/other850.8 (0.6–0.99)
Type of travel
 Temporary duty assignment (ref)84
 Deployment2723.5 (2.7–4.7)1.7 (1.2–2.4).006
 Exercise1151.1 (0.8–1.4)0.5 (0.3–0.8).004
Travel duration >6 wk3873.2 (2.5–4.2)2.2 (1.6–3.1)<.001
Geographic regiona
 US Southern Command (SOUTHCOM) (ref)45
 US Indo-Pacific Command (INDOPACOM)1570.7 (0.4–0.96)1.8 (1.1–3.1).021
 US Africa command (AFRICOM)1410.7 (0.5–1.1)1.6 (1.0–2.6).032
 US Central Command (CENTCOM)952.1 (1.3–3.3)2.5 (1.5–4.1)<.001
 US European Command (EUCOM)151.2 (0.6–2.3)1.7 (0.8–3.9).169
 Multiple geographic regions181.6 (0.8–3.1)1.8 (0.9–3.7).125
Hotel without air conditioning, tent, or dormitory/barracks4011.4 (1.0–1.9)
Environmental exposures—wading in fresh water, rodent exposure, working in abandoned buildings or an animal slaughter areab2382.0 (1.6–2.5)1.5 (1.1–1.9).004
Partial compliance or noncompliance with malaria chemoprophylaxisc1531.4 (1.1–1.8)
Close contact with localsd3301.3 (1.1–1.7)1.7 (1.3–2.1)<.001
Inability to wash or sanitize hands before meals1271.8 (1.4–2.3)1.6 (1.2–2.1).001
Consuming food from street vendors2122.4 (1.9–3.0)1.8 (1.4–2.4)<.001
ID Syndrome Impacting Daily Activities (n = 471)Univariate OR (95% CI)Multivariate OR (95% CI)P Value
Age, y4711.01 (0.99–1.02)
Male gender4111.1 (0.8–1.5)
Race
 Caucasian (ref)386
 Black/other850.8 (0.6–0.99)
Type of travel
 Temporary duty assignment (ref)84
 Deployment2723.5 (2.7–4.7)1.7 (1.2–2.4).006
 Exercise1151.1 (0.8–1.4)0.5 (0.3–0.8).004
Travel duration >6 wk3873.2 (2.5–4.2)2.2 (1.6–3.1)<.001
Geographic regiona
 US Southern Command (SOUTHCOM) (ref)45
 US Indo-Pacific Command (INDOPACOM)1570.7 (0.4–0.96)1.8 (1.1–3.1).021
 US Africa command (AFRICOM)1410.7 (0.5–1.1)1.6 (1.0–2.6).032
 US Central Command (CENTCOM)952.1 (1.3–3.3)2.5 (1.5–4.1)<.001
 US European Command (EUCOM)151.2 (0.6–2.3)1.7 (0.8–3.9).169
 Multiple geographic regions181.6 (0.8–3.1)1.8 (0.9–3.7).125
Hotel without air conditioning, tent, or dormitory/barracks4011.4 (1.0–1.9)
Environmental exposures—wading in fresh water, rodent exposure, working in abandoned buildings or an animal slaughter areab2382.0 (1.6–2.5)1.5 (1.1–1.9).004
Partial compliance or noncompliance with malaria chemoprophylaxisc1531.4 (1.1–1.8)
Close contact with localsd3301.3 (1.1–1.7)1.7 (1.3–2.1)<.001
Inability to wash or sanitize hands before meals1271.8 (1.4–2.3)1.6 (1.2–2.1).001
Consuming food from street vendors2122.4 (1.9–3.0)1.8 (1.4–2.4)<.001

Abbreviations: ID, infectious diseases; OR, odds ratio.

a

Geographic regions were based on the United States Department of Defense areas of responsibility for command and control of US military forces.

b

Abstracted from post-travel survey: “Did you have any exposure to rats including old, abandoned buildings or working in an animal slaughter area?” and “Did you have contact with fresh water from lakes, streams, or rivers (wading/bathing/swimming/etc.)? Do not include swimming pools.”

c

Travel to malaria-endemic region and malaria chemoprophylaxis prescription abstracted from predeployment visit. Dosing frequency and adherence with malaria prophylaxis abstracted from post-travel survey. Partial or noncompliance defined as missing any doses of a weekly antimalarial or >2 doses of a daily antimalarial.

d

Abstracted from post-travel survey; definition provided: “being within approximately 6 feet (2 meters) or within the room or care area for a prolonged period of time (eg, healthcare personnel, household members) or having direct contact with secretions.”

Table 3.

Risk Factors Associated With Infectious Disease Syndromes Impacting Daily Activities

ID Syndrome Impacting Daily Activities (n = 471)Univariate OR (95% CI)Multivariate OR (95% CI)P Value
Age, y4711.01 (0.99–1.02)
Male gender4111.1 (0.8–1.5)
Race
 Caucasian (ref)386
 Black/other850.8 (0.6–0.99)
Type of travel
 Temporary duty assignment (ref)84
 Deployment2723.5 (2.7–4.7)1.7 (1.2–2.4).006
 Exercise1151.1 (0.8–1.4)0.5 (0.3–0.8).004
Travel duration >6 wk3873.2 (2.5–4.2)2.2 (1.6–3.1)<.001
Geographic regiona
 US Southern Command (SOUTHCOM) (ref)45
 US Indo-Pacific Command (INDOPACOM)1570.7 (0.4–0.96)1.8 (1.1–3.1).021
 US Africa command (AFRICOM)1410.7 (0.5–1.1)1.6 (1.0–2.6).032
 US Central Command (CENTCOM)952.1 (1.3–3.3)2.5 (1.5–4.1)<.001
 US European Command (EUCOM)151.2 (0.6–2.3)1.7 (0.8–3.9).169
 Multiple geographic regions181.6 (0.8–3.1)1.8 (0.9–3.7).125
Hotel without air conditioning, tent, or dormitory/barracks4011.4 (1.0–1.9)
Environmental exposures—wading in fresh water, rodent exposure, working in abandoned buildings or an animal slaughter areab2382.0 (1.6–2.5)1.5 (1.1–1.9).004
Partial compliance or noncompliance with malaria chemoprophylaxisc1531.4 (1.1–1.8)
Close contact with localsd3301.3 (1.1–1.7)1.7 (1.3–2.1)<.001
Inability to wash or sanitize hands before meals1271.8 (1.4–2.3)1.6 (1.2–2.1).001
Consuming food from street vendors2122.4 (1.9–3.0)1.8 (1.4–2.4)<.001
ID Syndrome Impacting Daily Activities (n = 471)Univariate OR (95% CI)Multivariate OR (95% CI)P Value
Age, y4711.01 (0.99–1.02)
Male gender4111.1 (0.8–1.5)
Race
 Caucasian (ref)386
 Black/other850.8 (0.6–0.99)
Type of travel
 Temporary duty assignment (ref)84
 Deployment2723.5 (2.7–4.7)1.7 (1.2–2.4).006
 Exercise1151.1 (0.8–1.4)0.5 (0.3–0.8).004
Travel duration >6 wk3873.2 (2.5–4.2)2.2 (1.6–3.1)<.001
Geographic regiona
 US Southern Command (SOUTHCOM) (ref)45
 US Indo-Pacific Command (INDOPACOM)1570.7 (0.4–0.96)1.8 (1.1–3.1).021
 US Africa command (AFRICOM)1410.7 (0.5–1.1)1.6 (1.0–2.6).032
 US Central Command (CENTCOM)952.1 (1.3–3.3)2.5 (1.5–4.1)<.001
 US European Command (EUCOM)151.2 (0.6–2.3)1.7 (0.8–3.9).169
 Multiple geographic regions181.6 (0.8–3.1)1.8 (0.9–3.7).125
Hotel without air conditioning, tent, or dormitory/barracks4011.4 (1.0–1.9)
Environmental exposures—wading in fresh water, rodent exposure, working in abandoned buildings or an animal slaughter areab2382.0 (1.6–2.5)1.5 (1.1–1.9).004
Partial compliance or noncompliance with malaria chemoprophylaxisc1531.4 (1.1–1.8)
Close contact with localsd3301.3 (1.1–1.7)1.7 (1.3–2.1)<.001
Inability to wash or sanitize hands before meals1271.8 (1.4–2.3)1.6 (1.2–2.1).001
Consuming food from street vendors2122.4 (1.9–3.0)1.8 (1.4–2.4)<.001

Abbreviations: ID, infectious diseases; OR, odds ratio.

a

Geographic regions were based on the United States Department of Defense areas of responsibility for command and control of US military forces.

b

Abstracted from post-travel survey: “Did you have any exposure to rats including old, abandoned buildings or working in an animal slaughter area?” and “Did you have contact with fresh water from lakes, streams, or rivers (wading/bathing/swimming/etc.)? Do not include swimming pools.”

c

Travel to malaria-endemic region and malaria chemoprophylaxis prescription abstracted from predeployment visit. Dosing frequency and adherence with malaria prophylaxis abstracted from post-travel survey. Partial or noncompliance defined as missing any doses of a weekly antimalarial or >2 doses of a daily antimalarial.

d

Abstracted from post-travel survey; definition provided: “being within approximately 6 feet (2 meters) or within the room or care area for a prolonged period of time (eg, healthcare personnel, household members) or having direct contact with secretions.”

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